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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NFATC2_NFATC3

Z-value: 1.12

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
ENSG00000101096.15 NFATC2
ENSG00000072736.14 NFATC3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC2hg19_v2_chr20_-_50179368_50179392-0.629.8e-02Click!
NFATC3hg19_v2_chr16_+_68119764_681198680.492.2e-01Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_209602771 3.09 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr1_+_209602609 2.56 ENST00000458250.1
MIR205HG
MIR205 host gene (non-protein coding)
chr18_+_29027696 2.48 ENST00000257189.4
DSG3
desmoglein 3
chr15_+_43885252 2.04 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43985084 1.98 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr5_+_140186647 1.81 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr5_+_140254884 1.81 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr7_-_41742697 1.69 ENST00000242208.4
INHBA
inhibin, beta A
chr6_-_136788001 1.52 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr1_+_44401479 1.48 ENST00000438616.3
ARTN
artemin
chr5_+_140220769 1.45 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr6_+_150464155 1.32 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr2_-_216003127 1.30 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr4_-_11431389 1.30 ENST00000002596.5
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_+_46640750 1.22 ENST00000372003.1
TSPAN1
tetraspanin 1
chr5_+_140207536 1.18 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr5_+_140248518 1.16 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr14_+_65171315 1.16 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr5_+_140261703 1.10 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr18_-_47376197 1.08 ENST00000592688.1
MYO5B
myosin VB
chr5_+_140213815 1.08 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr11_+_128563652 1.05 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr18_-_24129367 1.04 ENST00000408011.3
KCTD1
potassium channel tetramerization domain containing 1
chr3_-_56809685 1.04 ENST00000413728.2
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr20_+_58179582 1.00 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr5_+_66124590 0.99 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr10_-_116444371 0.93 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chrX_-_15683147 0.93 ENST00000380342.3
TMEM27
transmembrane protein 27
chr11_-_72492878 0.90 ENST00000535054.1
ENST00000545082.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr20_+_44637526 0.85 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr18_+_61442629 0.84 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr5_+_167718604 0.83 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr11_-_72492903 0.80 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr18_-_24237339 0.80 ENST00000580191.1
KCTD1
potassium channel tetramerization domain containing 1
chr1_-_207206092 0.79 ENST00000359470.5
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr6_+_106534192 0.79 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr17_-_56492989 0.76 ENST00000583753.1
RNF43
ring finger protein 43
chr14_+_65171099 0.76 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_+_15246501 0.74 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr8_-_95274536 0.74 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr6_+_106546808 0.71 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr5_+_140165876 0.70 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr2_+_198570081 0.69 ENST00000282276.6
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr14_-_61748550 0.69 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr1_+_44398943 0.69 ENST00000372359.5
ENST00000414809.3
ARTN
artemin
chr17_+_16120512 0.68 ENST00000581006.1
ENST00000584797.1
ENST00000498772.2
ENST00000225609.5
ENST00000395844.4
ENST00000477745.1
PIGL
phosphatidylinositol glycan anchor biosynthesis, class L
chr8_-_15095832 0.68 ENST00000382080.1
SGCZ
sarcoglycan, zeta
chr12_-_50616122 0.67 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr5_+_140180635 0.67 ENST00000522353.2
ENST00000532566.2
PCDHA3
protocadherin alpha 3
chr5_-_78808617 0.65 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chrX_+_105937068 0.64 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr15_+_43985725 0.63 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr14_-_23623577 0.63 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr10_+_47746929 0.62 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr4_+_100737954 0.59 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr7_-_25702669 0.58 ENST00000446840.1
AC003090.1
AC003090.1
chr14_+_61789382 0.57 ENST00000555082.1
PRKCH
protein kinase C, eta
chr12_-_6484715 0.57 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr12_-_50616382 0.56 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr8_+_98900132 0.54 ENST00000520016.1
MATN2
matrilin 2
chr3_+_140981456 0.53 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr6_-_11779403 0.53 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr8_+_128748466 0.53 ENST00000524013.1
ENST00000520751.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr7_-_156803329 0.52 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr1_-_160990886 0.52 ENST00000537746.1
F11R
F11 receptor
chr5_+_140201183 0.51 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr1_+_82266053 0.51 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr5_+_140174429 0.51 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
PCDHA2
protocadherin alpha 2
chr18_+_55888767 0.51 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_-_113594279 0.49 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr11_-_88070920 0.47 ENST00000524463.1
ENST00000227266.5
CTSC
cathepsin C
chr11_-_88070896 0.46 ENST00000529974.1
ENST00000527018.1
CTSC
cathepsin C
chr2_-_165424973 0.46 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chrX_-_133792480 0.46 ENST00000359237.4
PLAC1
placenta-specific 1
chr6_-_11779840 0.45 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr2_+_162272605 0.44 ENST00000389554.3
TBR1
T-box, brain, 1
chr17_+_74372662 0.43 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr17_-_46657473 0.43 ENST00000332503.5
HOXB4
homeobox B4
chr15_+_45722727 0.43 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr18_-_53089723 0.43 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr2_-_74667612 0.42 ENST00000305557.5
ENST00000233330.6
RTKN
rhotekin
chr7_-_71868354 0.41 ENST00000412588.1
CALN1
calneuron 1
chr17_-_39093672 0.41 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr13_-_86373536 0.41 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr6_-_11779174 0.40 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_+_156117149 0.40 ENST00000435124.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_-_20256965 0.40 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr3_+_111718173 0.40 ENST00000494932.1
TAGLN3
transgelin 3
chr14_+_32546274 0.39 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr12_-_52828147 0.39 ENST00000252245.5
KRT75
keratin 75
chr19_-_55881741 0.39 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr20_-_14318248 0.38 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr12_+_83080659 0.38 ENST00000321196.3
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr7_-_121944491 0.38 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr15_-_52587945 0.38 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C
myosin VC
chr6_-_47010061 0.37 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr4_-_153274078 0.36 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_-_54779511 0.35 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr13_-_46716969 0.35 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_323689 0.35 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr8_-_17555164 0.34 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr4_-_72649763 0.34 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr4_+_71200681 0.34 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chr4_-_71532339 0.34 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr7_+_140373619 0.33 ENST00000483369.1
ADCK2
aarF domain containing kinase 2
chr1_+_247579451 0.33 ENST00000391828.3
ENST00000366497.2
NLRP3
NLR family, pyrin domain containing 3
chr18_-_52989217 0.33 ENST00000570287.2
TCF4
transcription factor 4
chr20_+_55204351 0.33 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr17_-_39274606 0.33 ENST00000391413.2
KRTAP4-11
keratin associated protein 4-11
chr18_-_53070913 0.33 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr10_+_111967345 0.32 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr4_-_100356291 0.32 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr14_+_32546145 0.32 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr5_+_135394840 0.32 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr13_+_97928395 0.32 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr6_+_43739697 0.31 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chrX_-_117107542 0.31 ENST00000371878.1
KLHL13
kelch-like family member 13
chr9_+_125376948 0.31 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr1_+_24646002 0.31 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr19_+_41281416 0.31 ENST00000597140.1
MIA
melanoma inhibitory activity
chr1_-_156675535 0.31 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr13_+_97874574 0.31 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr19_-_49567124 0.31 ENST00000301411.3
NTF4
neurotrophin 4
chr12_-_71031220 0.30 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_-_124839648 0.30 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr12_-_71031185 0.30 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chrX_+_56259316 0.30 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr17_+_30814707 0.30 ENST00000584792.1
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr6_-_13487784 0.30 ENST00000379287.3
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr17_+_38334242 0.30 ENST00000436615.3
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr9_+_115913222 0.29 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr2_+_42104692 0.29 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chrX_-_117107680 0.29 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chr22_-_39640756 0.29 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr5_-_77844974 0.29 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr17_-_46688334 0.29 ENST00000239165.7
HOXB7
homeobox B7
chr4_-_22444733 0.28 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr8_+_86121448 0.27 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr4_+_69313145 0.27 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr12_-_24103954 0.27 ENST00000441133.2
ENST00000545921.1
SOX5
SRY (sex determining region Y)-box 5
chr19_+_41281282 0.27 ENST00000263369.3
MIA
melanoma inhibitory activity
chr10_+_118305435 0.27 ENST00000369221.2
PNLIP
pancreatic lipase
chr18_-_52989525 0.27 ENST00000457482.3
TCF4
transcription factor 4
chr20_+_1875110 0.27 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr3_-_27763803 0.27 ENST00000449599.1
EOMES
eomesodermin
chr18_-_53069419 0.27 ENST00000570177.2
TCF4
transcription factor 4
chr4_+_155665123 0.27 ENST00000336356.3
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr1_-_156675368 0.26 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr1_-_183559693 0.26 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr14_-_21562648 0.26 ENST00000555270.1
ZNF219
zinc finger protein 219
chr3_-_141747950 0.26 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr18_-_67872891 0.26 ENST00000454359.1
ENST00000437017.1
RTTN
rotatin
chr1_+_100503643 0.26 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr11_+_55578854 0.26 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr1_+_24645807 0.25 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_153538011 0.25 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr17_-_74528128 0.25 ENST00000590175.1
CYGB
cytoglobin
chr1_+_24645865 0.25 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr9_-_117692697 0.25 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr11_+_34654011 0.25 ENST00000531794.1
EHF
ets homologous factor
chr10_+_71561630 0.25 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr8_+_80523321 0.25 ENST00000518111.1
STMN2
stathmin-like 2
chr5_+_38845960 0.25 ENST00000502536.1
OSMR
oncostatin M receptor
chr18_-_53068911 0.25 ENST00000537856.3
TCF4
transcription factor 4
chr12_-_109747023 0.25 ENST00000355216.1
ENST00000299162.5
FOXN4
forkhead box N4
chr18_-_53257027 0.25 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr9_+_103204553 0.25 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr3_-_27764190 0.25 ENST00000537516.1
EOMES
eomesodermin
chr19_+_41281060 0.24 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr11_-_57089671 0.24 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr17_+_55162453 0.24 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr12_+_11802753 0.24 ENST00000396373.4
ETV6
ets variant 6
chr17_-_7197881 0.24 ENST00000007699.5
YBX2
Y box binding protein 2
chr1_-_153521597 0.23 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr13_-_41240717 0.23 ENST00000379561.5
FOXO1
forkhead box O1
chr1_-_41131326 0.23 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr17_-_17740325 0.23 ENST00000338854.5
SREBF1
sterol regulatory element binding transcription factor 1
chr4_-_153303658 0.23 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_+_9482551 0.23 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143
zinc finger protein 143
chr3_+_193853927 0.23 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr8_-_17533838 0.23 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr8_-_95449155 0.23 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr6_-_13487825 0.22 ENST00000603223.1
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_-_226926864 0.22 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr10_-_105615164 0.22 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chrY_-_2655644 0.22 ENST00000525526.2
ENST00000534739.2
ENST00000383070.1
SRY
sex determining region Y
chr6_-_47009996 0.22 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr4_-_123377880 0.22 ENST00000226730.4
IL2
interleukin 2
chr8_-_91095099 0.22 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr1_+_145413268 0.22 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chr14_+_75536280 0.22 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr1_+_174846570 0.22 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_184079382 0.22 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
CLCN2
chloride channel, voltage-sensitive 2
chr8_-_28243590 0.21 ENST00000523095.1
ENST00000522795.1
ZNF395
zinc finger protein 395
chr19_+_13134772 0.21 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr13_+_80055284 0.21 ENST00000218652.7
NDFIP2
Nedd4 family interacting protein 2
chr11_-_75062829 0.21 ENST00000393505.4
ARRB1
arrestin, beta 1
chrX_+_105192423 0.21 ENST00000540278.1
NRK
Nik related kinase
chr4_-_143226979 0.21 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr13_+_80055581 0.21 ENST00000487865.1
NDFIP2
Nedd4 family interacting protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 2.2 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.3 1.3 GO:0035627 ceramide transport(GO:0035627)
0.3 1.5 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.3 2.6 GO:0006600 creatine metabolic process(GO:0006600)
0.2 0.5 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 0.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.5 GO:0090094 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.2 0.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 0.7 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.6 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 1.7 GO:0032782 bile acid secretion(GO:0032782)
0.1 1.1 GO:0032439 endosome localization(GO:0032439)
0.1 0.6 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.4 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 0.3 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.9 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.2 GO:2000974 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.5 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.3 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.4 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.3 GO:0021622 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 13.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.6 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.6 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.1 0.2 GO:0070997 neuron death(GO:0070997)
0.1 0.2 GO:0050777 negative regulation of immune response(GO:0050777)
0.1 0.2 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.2 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 1.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.8 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0007619 courtship behavior(GO:0007619)
0.0 0.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.2 GO:2000020 positive regulation of male gonad development(GO:2000020)
0.0 0.3 GO:0050890 cognition(GO:0050890)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.7 GO:0015695 organic cation transport(GO:0015695)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.3 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.9 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.0 GO:0042704 uterine wall breakdown(GO:0042704)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0046479 ganglioside catabolic process(GO:0006689) glycosphingolipid catabolic process(GO:0046479)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:1902722 positive regulation of prolactin secretion(GO:1902722)
0.0 0.0 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 1.6 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.0 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.3 GO:0051023 regulation of immunoglobulin secretion(GO:0051023)
0.0 0.0 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.0 GO:2000319 regulation of T-helper 17 cell differentiation(GO:2000319)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:2000909 negative regulation of cytokine secretion involved in immune response(GO:0002740) regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 1.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.2 GO:0045179 apical cortex(GO:0045179)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.5 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.0 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.6 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.0 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 2.6 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.3 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 2.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.7 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 1.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.4 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.1 GO:0045159 myosin II binding(GO:0045159)
0.1 0.3 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.9 GO:0031404 chloride ion binding(GO:0031404)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 2.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 2.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway