Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
NFATC4 Links Ensembl NCBI GeneCards UniProt	ENSG00000100968.9	NFATC4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NFATC4	hg19_v2_chr14_+_24837226_24837547	0.25	5.4e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr13_+_102104980	3.49	ENST00000545560.2	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr14_-_92413353	2.58	ENST00000556154.1	FBLN5	fibulin 5
chr1_-_57045228	2.41	ENST00000371250.3	PPAP2B	phosphatidic acid phosphatase type 2B
chr2_-_190044480	2.34	ENST00000374866.3	COL5A2	collagen, type V, alpha 2
chr1_+_163038565	2.34	ENST00000421743.2	RGS4	regulator of G-protein signaling 4
chr14_-_30396948	2.22	ENST00000331968.5	PRKD1	protein kinase D1
chr2_+_189839046	2.03	ENST00000304636.3 ENST00000317840.5	COL3A1	collagen, type III, alpha 1
chr8_-_120685608	1.91	ENST00000427067.2	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_+_152214098	1.78	ENST00000243347.3	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr14_-_30396802	1.71	ENST00000415220.2	PRKD1	protein kinase D1
chr2_-_238322800	1.63	ENST00000392004.3 ENST00000433762.1 ENST00000347401.3 ENST00000353578.4 ENST00000346358.4 ENST00000392003.2	COL6A3	collagen, type VI, alpha 3
chr2_-_238323007	1.60	ENST00000295550.4	COL6A3	collagen, type VI, alpha 3
chr2_-_238322770	1.60	ENST00000472056.1	COL6A3	collagen, type VI, alpha 3
chr12_-_47219733	1.50	ENST00000547477.1 ENST00000447411.1 ENST00000266579.4	SLC38A4	solute carrier family 38, member 4
chr8_+_17434689	1.50	ENST00000398074.3	PDGFRL	platelet-derived growth factor receptor-like
chr6_-_152639479	1.30	ENST00000356820.4	SYNE1	spectrin repeat containing, nuclear envelope 1
chrX_+_86772787	1.25	ENST00000373114.4	KLHL4	kelch-like family member 4
chr13_-_33859819	1.21	ENST00000336934.5	STARD13	StAR-related lipid transfer (START) domain containing 13
chr1_+_162602244	1.18	ENST00000367922.3 ENST00000367921.3	DDR2	discoidin domain receptor tyrosine kinase 2
chr12_-_56106060	1.14	ENST00000452168.2	ITGA7	integrin, alpha 7
chr1_+_164528866	1.13	ENST00000420696.2	PBX1	pre-B-cell leukemia homeobox 1
chr6_-_167275991	1.12	ENST00000510118.1	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr5_-_124081008	1.09	ENST00000306315.5	ZNF608	zinc finger protein 608
chr6_-_167276033	1.09	ENST00000503859.1 ENST00000506565.1	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr3_+_69812877	1.07	ENST00000457080.1 ENST00000328528.6	MITF	microphthalmia-associated transcription factor
chr8_+_70404996	1.05	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr7_+_20687017	1.04	ENST00000258738.6	ABCB5	ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr8_-_13372253	1.03	ENST00000316609.5	DLC1	deleted in liver cancer 1
chr2_-_179343268	0.99	ENST00000424785.2	FKBP7	FK506 binding protein 7
chrX_+_86772707	0.98	ENST00000373119.4	KLHL4	kelch-like family member 4
chr8_-_57123815	0.97	ENST00000316981.3 ENST00000423799.2 ENST00000429357.2	PLAG1	pleiomorphic adenoma gene 1
chr2_-_179343226	0.94	ENST00000434643.2	FKBP7	FK506 binding protein 7
chr20_+_12989596	0.93	ENST00000434210.1 ENST00000399002.2	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chr14_+_21156915	0.92	ENST00000397990.4 ENST00000555597.1	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr1_+_78470530	0.92	ENST00000370763.5	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_+_82767284	0.88	ENST00000265077.3	VCAN	versican
chr4_-_70626314	0.88	ENST00000510821.1	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr12_+_51318513	0.81	ENST00000332160.4	METTL7A	methyltransferase like 7A
chr10_-_62704005	0.80	ENST00000337910.5	RHOBTB1	Rho-related BTB domain containing 1
chr1_-_145470383	0.80	ENST00000369314.1 ENST00000369313.3	POLR3GL	polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr14_-_89883412	0.79	ENST00000557258.1	FOXN3	forkhead box N3
chr11_+_19799327	0.77	ENST00000540292.1	NAV2	neuron navigator 2
chr7_-_19157248	0.76	ENST00000242261.5	TWIST1	twist family bHLH transcription factor 1
chr4_-_1670632	0.76	ENST00000461064.1	FAM53A	family with sequence similarity 53, member A
chr14_+_29236269	0.73	ENST00000313071.4	FOXG1	forkhead box G1
chrX_+_22056165	0.73	ENST00000535894.1	PHEX	phosphate regulating endopeptidase homolog, X-linked
chr20_+_33292068	0.72	ENST00000374810.3 ENST00000374809.2 ENST00000451665.1	TP53INP2	tumor protein p53 inducible nuclear protein 2
chr1_+_164529004	0.71	ENST00000559240.1 ENST00000367897.1 ENST00000540236.1 ENST00000401534.1	PBX1	pre-B-cell leukemia homeobox 1
chr3_+_154797428	0.70	ENST00000460393.1	MME	membrane metallo-endopeptidase
chr3_-_112329110	0.69	ENST00000479368.1	CCDC80	coiled-coil domain containing 80
chr7_+_18535854	0.68	ENST00000401921.1	HDAC9	histone deacetylase 9
chr4_-_107957454	0.68	ENST00000285311.3	DKK2	dickkopf WNT signaling pathway inhibitor 2
chr14_+_29234870	0.67	ENST00000382535.3	FOXG1	forkhead box G1
chr3_-_18480260	0.67	ENST00000454909.2	SATB1	SATB homeobox 1
chr11_-_96076334	0.66	ENST00000524717.1	MAML2	mastermind-like 2 (Drosophila)
chr2_-_175712270	0.66	ENST00000295497.7 ENST00000444394.1	CHN1	chimerin 1
chr18_+_66465302	0.65	ENST00000360242.5 ENST00000358653.5	CCDC102B	coiled-coil domain containing 102B
chr1_+_36789335	0.65	ENST00000373137.2	RP11-268J15.5	RP11-268J15.5
chrX_+_9431324	0.64	ENST00000407597.2 ENST00000424279.1 ENST00000536365.1 ENST00000441088.1 ENST00000380961.1 ENST00000415293.1	TBL1X	transducin (beta)-like 1X-linked
chr10_-_33623564	0.64	ENST00000374875.1 ENST00000374822.4	NRP1	neuropilin 1
chr2_+_23608064	0.64	ENST00000486442.1	KLHL29	kelch-like family member 29
chr7_-_92777606	0.63	ENST00000437805.1 ENST00000446959.1 ENST00000439952.1 ENST00000414791.1 ENST00000446033.1 ENST00000411955.1 ENST00000318238.4	SAMD9L	sterile alpha motif domain containing 9-like
chr16_+_2039946	0.62	ENST00000248121.2 ENST00000568896.1	SYNGR3	synaptogyrin 3
chr9_+_92219919	0.62	ENST00000252506.6 ENST00000375769.1	GADD45G	growth arrest and DNA-damage-inducible, gamma
chr1_-_85870177	0.62	ENST00000542148.1	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr1_+_79115503	0.59	ENST00000370747.4 ENST00000438486.1 ENST00000545124.1	IFI44	interferon-induced protein 44
chr11_+_65190245	0.57	ENST00000499732.1 ENST00000501122.2 ENST00000601801.1	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr2_-_101767715	0.55	ENST00000376840.4 ENST00000409318.1	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr3_+_46618727	0.55	ENST00000296145.5	TDGF1	teratocarcinoma-derived growth factor 1
chr16_-_73093597	0.55	ENST00000397992.5	ZFHX3	zinc finger homeobox 3
chr11_+_77532155	0.54	ENST00000532481.1 ENST00000526415.1 ENST00000393427.2 ENST00000527134.1 ENST00000304716.8	AAMDC	adipogenesis associated, Mth938 domain containing
chr3_-_114790179	0.54	ENST00000462705.1	ZBTB20	zinc finger and BTB domain containing 20
chr11_+_77532233	0.53	ENST00000525409.1	AAMDC	adipogenesis associated, Mth938 domain containing
chr2_+_201994569	0.53	ENST00000457277.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr15_+_62853562	0.52	ENST00000561311.1	TLN2	talin 2
chr2_+_201994042	0.52	ENST00000417748.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr1_-_155881156	0.52	ENST00000539040.1 ENST00000368323.3	RIT1	Ras-like without CAAX 1
chr7_+_120628731	0.50	ENST00000310396.5	CPED1	cadherin-like and PC-esterase domain containing 1
chr18_-_60987220	0.50	ENST00000398117.1	BCL2	B-cell CLL/lymphoma 2
chr6_-_53530474	0.50	ENST00000370905.3	KLHL31	kelch-like family member 31
chr2_+_27301435	0.50	ENST00000380320.4	EMILIN1	elastin microfibril interfacer 1
chr20_+_18125727	0.49	ENST00000489634.2	CSRP2BP	CSRP2 binding protein
chr14_-_74551096	0.48	ENST00000350259.4	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr1_-_150780757	0.47	ENST00000271651.3	CTSK	cathepsin K
chr6_-_24489842	0.47	ENST00000230036.1	GPLD1	glycosylphosphatidylinositol specific phospholipase D1
chr6_+_155537771	0.46	ENST00000275246.7	TIAM2	T-cell lymphoma invasion and metastasis 2
chr19_+_30863271	0.45	ENST00000355537.3	ZNF536	zinc finger protein 536
chr20_+_33464238	0.45	ENST00000360596.2	ACSS2	acyl-CoA synthetase short-chain family member 2
chr19_-_36909528	0.44	ENST00000392161.3 ENST00000392171.1	ZFP82	ZFP82 zinc finger protein
chr16_-_2260834	0.44	ENST00000562360.1 ENST00000566018.1	BRICD5	BRICHOS domain containing 5
chr6_-_15586238	0.44	ENST00000462989.2	DTNBP1	dystrobrevin binding protein 1
chr12_+_12938541	0.44	ENST00000356591.4	APOLD1	apolipoprotein L domain containing 1
chr20_-_30310693	0.43	ENST00000307677.4 ENST00000420653.1	BCL2L1	BCL2-like 1
chr10_-_33623310	0.43	ENST00000395995.1 ENST00000374823.5 ENST00000374821.5 ENST00000374816.3	NRP1	neuropilin 1
chr3_+_148545586	0.43	ENST00000282957.4 ENST00000468341.1	CPB1	carboxypeptidase B1 (tissue)
chr3_-_114035026	0.43	ENST00000570269.1	RP11-553L6.5	RP11-553L6.5
chr14_-_75593708	0.43	ENST00000557673.1 ENST00000238616.5	NEK9	NIMA-related kinase 9
chr1_-_146082633	0.42	ENST00000605317.1 ENST00000604938.1 ENST00000339388.5	NBPF11	neuroblastoma breakpoint family, member 11
chr5_-_177423243	0.41	ENST00000308304.2	PROP1	PROP paired-like homeobox 1
chr15_-_91475747	0.41	ENST00000330334.3 ENST00000559898.1 ENST00000394272.3	HDDC3	HD domain containing 3
chr18_-_3247084	0.41	ENST00000609924.1	RP13-270P17.3	RP13-270P17.3
chr11_+_27015628	0.41	ENST00000318627.2	FIBIN	fin bud initiation factor homolog (zebrafish)
chr20_-_45985464	0.40	ENST00000458360.2 ENST00000262975.4	ZMYND8	zinc finger, MYND-type containing 8
chr20_-_45061695	0.40	ENST00000445496.2	ELMO2	engulfment and cell motility 2
chr3_-_73673991	0.40	ENST00000308537.4 ENST00000263666.4	PDZRN3	PDZ domain containing ring finger 3
chr20_-_45985414	0.39	ENST00000461685.1 ENST00000372023.3 ENST00000540497.1 ENST00000435836.1 ENST00000471951.2 ENST00000352431.2 ENST00000396281.4 ENST00000355972.4 ENST00000360911.3	ZMYND8	zinc finger, MYND-type containing 8
chr15_-_37393406	0.39	ENST00000338564.5 ENST00000558313.1 ENST00000340545.5	MEIS2	Meis homeobox 2
chr7_+_138943265	0.39	ENST00000483726.1	UBN2	ubinuclein 2
chr14_+_88471468	0.38	ENST00000267549.3	GPR65	G protein-coupled receptor 65
chr8_-_25281747	0.38	ENST00000421054.2	GNRH1	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr20_-_45985172	0.38	ENST00000536340.1	ZMYND8	zinc finger, MYND-type containing 8
chr7_-_14942283	0.38	ENST00000402815.1	DGKB	diacylglycerol kinase, beta 90kDa
chrX_-_134478012	0.37	ENST00000370766.3	ZNF75D	zinc finger protein 75D
chr12_+_56511943	0.37	ENST00000257940.2 ENST00000552345.1 ENST00000551880.1 ENST00000546903.1 ENST00000551790.1	ZC3H10 ESYT1	zinc finger CCCH-type containing 10 extended synaptotagmin-like protein 1
chr15_+_32933866	0.37	ENST00000300175.4 ENST00000413748.2 ENST00000494364.1 ENST00000497208.1	SCG5	secretogranin V (7B2 protein)
chr14_+_88852059	0.37	ENST00000045347.7	SPATA7	spermatogenesis associated 7
chr9_+_104161123	0.37	ENST00000374861.3 ENST00000339664.2 ENST00000259395.4	ZNF189	zinc finger protein 189
chr15_-_77712477	0.36	ENST00000560626.2	PEAK1	pseudopodium-enriched atypical kinase 1
chrX_-_77041685	0.36	ENST00000373344.5 ENST00000395603.3	ATRX	alpha thalassemia/mental retardation syndrome X-linked
chr14_-_74551172	0.36	ENST00000553458.1	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr10_+_81838792	0.35	ENST00000372273.3	TMEM254	transmembrane protein 254
chrX_+_134166333	0.35	ENST00000257013.7	FAM127A	family with sequence similarity 127, member A
chr19_-_53606604	0.35	ENST00000599056.1 ENST00000599247.1 ENST00000355147.5 ENST00000429604.1 ENST00000418871.1 ENST00000599637.1	ZNF160	zinc finger protein 160
chr13_+_112721913	0.34	ENST00000330949.1	SOX1	SRY (sex determining region Y)-box 1
chrX_+_10124977	0.34	ENST00000380833.4	CLCN4	chloride channel, voltage-sensitive 4
chr12_-_90049828	0.33	ENST00000261173.2 ENST00000348959.3	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr1_-_113162040	0.33	ENST00000358039.4 ENST00000369668.2	ST7L	suppression of tumorigenicity 7 like
chr13_+_114462193	0.33	ENST00000375353.3	TMEM255B	transmembrane protein 255B
chr20_+_57466357	0.33	ENST00000371095.3 ENST00000371085.3 ENST00000354359.7 ENST00000265620.7	GNAS	GNAS complex locus
chr5_+_15500280	0.32	ENST00000504595.1	FBXL7	F-box and leucine-rich repeat protein 7
chr12_-_90049878	0.32	ENST00000359142.3	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr12_-_59314246	0.32	ENST00000320743.3	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
chr17_+_52978185	0.31	ENST00000572405.1 ENST00000572158.1 ENST00000540336.1 ENST00000572298.1 ENST00000536554.1 ENST00000575333.1 ENST00000570499.1 ENST00000572576.1	TOM1L1	target of myb1 (chicken)-like 1
chr1_+_99127265	0.31	ENST00000306121.3	SNX7	sorting nexin 7
chr4_+_26322185	0.31	ENST00000361572.6	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr17_+_76311791	0.31	ENST00000586321.1	AC061992.2	AC061992.2
chr5_-_42811986	0.31	ENST00000511224.1 ENST00000507920.1 ENST00000510965.1	SEPP1	selenoprotein P, plasma, 1
chr11_-_62474803	0.30	ENST00000533982.1 ENST00000360796.5	BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr9_-_113342160	0.30	ENST00000401783.2 ENST00000374461.1	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr5_+_43603229	0.30	ENST00000344920.4 ENST00000512996.2	NNT	nicotinamide nucleotide transhydrogenase
chr1_-_157670528	0.29	ENST00000368186.5 ENST00000496769.1	FCRL3	Fc receptor-like 3
chr6_+_64346386	0.29	ENST00000509330.1	PHF3	PHD finger protein 3
chr16_-_47493041	0.29	ENST00000565940.2	ITFG1	integrin alpha FG-GAP repeat containing 1
chr4_-_114900831	0.29	ENST00000315366.7	ARSJ	arylsulfatase family, member J
chr8_-_19459993	0.29	ENST00000454498.2 ENST00000520003.1	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr5_+_154238149	0.29	ENST00000519430.1 ENST00000520671.1 ENST00000521583.1 ENST00000518028.1 ENST00000519404.1 ENST00000519394.1 ENST00000518775.1	CNOT8	CCR4-NOT transcription complex, subunit 8
chr7_-_120498357	0.29	ENST00000415871.1 ENST00000222747.3 ENST00000430985.1	TSPAN12	tetraspanin 12
chr10_+_81838411	0.28	ENST00000372281.3 ENST00000372277.3 ENST00000372275.1 ENST00000372274.1	TMEM254	transmembrane protein 254
chr19_+_37095719	0.28	ENST00000423582.1	ZNF382	zinc finger protein 382
chr3_-_121740969	0.28	ENST00000393631.1 ENST00000273691.3 ENST00000344209.5	ILDR1	immunoglobulin-like domain containing receptor 1
chr5_+_118812237	0.28	ENST00000513628.1	HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4
chr11_-_47600320	0.28	ENST00000525720.1 ENST00000531067.1 ENST00000533290.1 ENST00000529499.1 ENST00000529946.1 ENST00000526005.1 ENST00000395288.2 ENST00000534239.1	KBTBD4	kelch repeat and BTB (POZ) domain containing 4
chr19_+_41856816	0.28	ENST00000539627.1	TMEM91	transmembrane protein 91
chr3_+_63953415	0.28	ENST00000484332.1	ATXN7	ataxin 7
chr6_-_43276535	0.27	ENST00000372569.3 ENST00000274990.4	CRIP3	cysteine-rich protein 3
chr1_+_146373546	0.27	ENST00000446760.2	NBPF12	neuroblastoma breakpoint family, member 12
chr2_+_204192942	0.27	ENST00000295851.5 ENST00000261017.5	ABI2	abl-interactor 2
chr2_+_201994208	0.27	ENST00000440180.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr12_-_58329888	0.27	ENST00000546580.1	RP11-620J15.3	RP11-620J15.3
chr12_-_71551652	0.27	ENST00000546561.1	TSPAN8	tetraspanin 8
chr9_-_13165457	0.27	ENST00000542239.1 ENST00000538841.1 ENST00000433359.2	MPDZ	multiple PDZ domain protein
chr5_+_43602750	0.26	ENST00000505678.2 ENST00000512422.1 ENST00000264663.5	NNT	nicotinamide nucleotide transhydrogenase
chr5_+_118812294	0.26	ENST00000509514.1	HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4
chr17_-_5389477	0.26	ENST00000572834.1 ENST00000570848.1 ENST00000571971.1 ENST00000158771.4	DERL2	derlin 2
chr19_+_16059818	0.26	ENST00000322107.1	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr11_-_124981475	0.26	ENST00000532156.1 ENST00000532407.1 ENST00000279968.4 ENST00000527766.1 ENST00000529583.1 ENST00000524373.1 ENST00000527271.1 ENST00000526175.1 ENST00000529609.1 ENST00000533273.1 ENST00000531909.1 ENST00000529530.1	TMEM218	transmembrane protein 218
chr7_-_26904317	0.26	ENST00000345317.2	SKAP2	src kinase associated phosphoprotein 2
chr19_+_39759154	0.26	ENST00000331982.5	IFNL2	interferon, lambda 2
chr5_+_72112470	0.26	ENST00000447967.2 ENST00000523768.1	TNPO1	transportin 1
chr4_-_52883786	0.25	ENST00000343457.3	LRRC66	leucine rich repeat containing 66
chr6_+_132873832	0.25	ENST00000275200.1	TAAR8	trace amine associated receptor 8
chr11_-_12030629	0.25	ENST00000396505.2	DKK3	dickkopf WNT signaling pathway inhibitor 3
chr11_-_47600549	0.25	ENST00000430070.2	KBTBD4	kelch repeat and BTB (POZ) domain containing 4
chr1_-_155177677	0.25	ENST00000368378.3 ENST00000541990.1 ENST00000457183.2	THBS3	thrombospondin 3
chrX_-_13835147	0.25	ENST00000493677.1 ENST00000355135.2	GPM6B	glycoprotein M6B
chr1_+_151512775	0.25	ENST00000368849.3 ENST00000392712.3 ENST00000353024.3 ENST00000368848.2 ENST00000538902.1	TUFT1	tuftelin 1
chr16_-_54963026	0.25	ENST00000560208.1 ENST00000557792.1	CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chrX_+_102631844	0.25	ENST00000372634.1 ENST00000299872.7	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr11_-_33757950	0.25	ENST00000533403.1 ENST00000528700.1 ENST00000527577.1 ENST00000395850.3 ENST00000351554.3	CD59	CD59 molecule, complement regulatory protein
chr12_-_49582978	0.25	ENST00000301071.7	TUBA1A	tubulin, alpha 1a
chr5_-_133510456	0.25	ENST00000520417.1	SKP1	S-phase kinase-associated protein 1
chr1_+_99127225	0.24	ENST00000370189.5 ENST00000529992.1	SNX7	sorting nexin 7
chr16_-_18887627	0.24	ENST00000563235.1	SMG1	SMG1 phosphatidylinositol 3-kinase-related kinase
chr3_+_108321623	0.24	ENST00000497905.1 ENST00000463306.1	DZIP3	DAZ interacting zinc finger protein 3
chr1_+_52521797	0.24	ENST00000313334.8	BTF3L4	basic transcription factor 3-like 4
chr17_+_53343577	0.24	ENST00000573945.1	HLF	hepatic leukemia factor
chr11_-_67141090	0.24	ENST00000312438.7	CLCF1	cardiotrophin-like cytokine factor 1
chr15_+_65914260	0.24	ENST00000261892.6 ENST00000339868.6	SLC24A1	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr2_-_97405775	0.23	ENST00000264963.4 ENST00000537039.1 ENST00000377079.4 ENST00000426463.2 ENST00000534882.1	LMAN2L	lectin, mannose-binding 2-like
chr1_-_113161730	0.23	ENST00000544629.1 ENST00000543570.1 ENST00000360743.4 ENST00000490067.1 ENST00000343210.7 ENST00000369666.1	ST7L	suppression of tumorigenicity 7 like
chr5_-_88178964	0.23	ENST00000513252.1 ENST00000508569.1 ENST00000510942.1 ENST00000506554.1	MEF2C	myocyte enhancer factor 2C
chr6_-_146057144	0.23	ENST00000367519.3	EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr6_+_6588902	0.23	ENST00000230568.4	LY86	lymphocyte antigen 86
chr17_-_58603568	0.23	ENST00000083182.3	APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr1_-_169599353	0.23	ENST00000367793.2 ENST00000367794.2 ENST00000367792.2 ENST00000367791.2 ENST00000367788.2	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)
chr10_-_7453445	0.22	ENST00000379713.3 ENST00000397167.1 ENST00000397160.3	SFMBT2	Scm-like with four mbt domains 2
chr19_+_36132631	0.22	ENST00000379026.2 ENST00000379023.4 ENST00000402764.2 ENST00000479824.1	ETV2	ets variant 2
chr1_-_68698197	0.22	ENST00000370973.2 ENST00000370971.1	WLS	wntless Wnt ligand secretion mediator
chr3_-_98241713	0.22	ENST00000502288.1 ENST00000512147.1 ENST00000510541.1 ENST00000503621.1 ENST00000511081.1	CLDND1	claudin domain containing 1
chr15_+_75498739	0.22	ENST00000565074.1	C15orf39	chromosome 15 open reading frame 39

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.6	3.9	GO:0089700	protein kinase D signaling(GO:0089700)
0.3	1.1	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
0.3	0.8	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2	1.1	GO:0038190	vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2	0.8	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2	1.9	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2	1.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.2	1.0	GO:0048749	compound eye development(GO:0048749)
0.2	2.6	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	1.2	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2	0.5	GO:1901297	positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2	0.9	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:0043366	beta selection(GO:0043366)
0.1	0.7	GO:1904383	response to sodium phosphate(GO:1904383)
0.1	0.7	GO:0046449	creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.1	0.5	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	1.3	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	1.3	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.5	GO:0032848	negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1	0.5	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1	1.8	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.6	GO:0006740	NADPH regeneration(GO:0006740)
0.1	0.5	GO:0019542	acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1	0.4	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	0.7	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.1	GO:0042223	positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.1	0.3	GO:2000777	positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1	0.8	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.4	GO:1990637	response to prolactin(GO:1990637)
0.1	0.5	GO:0036111	very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1	0.4	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	0.3	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	1.2	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.4	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.1	0.7	GO:1990034	cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1	0.3	GO:1905229	cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.1	0.5	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	1.0	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.2	GO:0046416	D-amino acid metabolic process(GO:0046416)
0.1	0.3	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1	1.5	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1	0.5	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.5	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.3	GO:0002251	organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.1	1.8	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	0.3	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.3	GO:1902613	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1	0.7	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.2	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.1	4.8	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.6	GO:0010265	SCF complex assembly(GO:0010265)
0.1	0.6	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.2	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.1	0.4	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	1.0	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.1	1.4	GO:0030728	ovulation(GO:0030728)
0.0	0.2	GO:1904647	response to rotenone(GO:1904647)
0.0	0.2	GO:0036309	protein localization to M-band(GO:0036309)
0.0	2.0	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:1901895	positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0	0.6	GO:1900038	negative regulation of cellular response to hypoxia(GO:1900038)
0.0	0.0	GO:0007521	muscle cell fate determination(GO:0007521)
0.0	0.2	GO:0007418	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.3	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.2	GO:0009609	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0	0.8	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.5	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	1.9	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.6	GO:0007265	Ras protein signal transduction(GO:0007265)
0.0	0.2	GO:0060048	cardiac muscle contraction(GO:0060048)
0.0	0.4	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.9	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.0	0.9	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.2	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0	0.5	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.4	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.2	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.1	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.6	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.2	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	0.1	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.0	0.1	GO:0014040	positive regulation of Schwann cell differentiation(GO:0014040)
0.0	0.4	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	1.2	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.3	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.4	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.6	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.2	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.1	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0	0.4	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.4	GO:0001956	positive regulation of neurotransmitter secretion(GO:0001956)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.2	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.3	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.6	GO:0060004	reflex(GO:0060004)
0.0	0.2	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.1	GO:0035701	immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701)
0.0	0.2	GO:0046874	quinolinate metabolic process(GO:0046874) pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.7	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.8	GO:0032259	methylation(GO:0032259)
0.0	0.0	GO:2000532	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of metanephric mesenchymal cell migration(GO:2000589)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.4	GO:0009642	response to light intensity(GO:0009642)
0.0	0.1	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	0.0	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.2	GO:0070269	pyroptosis(GO:0070269)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.3	GO:0072189	ureter development(GO:0072189)
0.0	0.5	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	1.2	GO:0034113	heterotypic cell-cell adhesion(GO:0034113)
0.0	0.3	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.0	0.9	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.3	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.5	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.1	GO:0003096	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0	0.4	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.3	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.6	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.0	0.1	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090100)
0.0	0.3	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.3	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.9	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.0	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.1	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.6	GO:0021762	substantia nigra development(GO:0021762)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0005588	collagen type V trimer(GO:0005588)
0.3	4.8	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	3.2	GO:0071953	elastic fiber(GO:0071953)
0.2	2.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	0.9	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	0.4	GO:0031933	telomeric heterochromatin(GO:0031933)
0.1	0.9	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.5	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	4.1	GO:0000421	autophagosome membrane(GO:0000421)
0.1	1.0	GO:0097443	sorting endosome(GO:0097443)
0.1	0.2	GO:0097058	CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1	1.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.5	GO:0036021	endolysosome lumen(GO:0036021)
0.1	1.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1	1.5	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.4	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.6	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0071159	NF-kappaB complex(GO:0071159)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	2.0	GO:0008305	integrin complex(GO:0008305)
0.0	0.2	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.1	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	3.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.3	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	2.6	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.7	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.8	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.6	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.3	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0008091	spectrin(GO:0008091)
0.0	0.3	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.0	0.2	GO:0097413	Lewy body(GO:0097413)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0	0.4	GO:0046930	pore complex(GO:0046930)
0.0	0.4	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.2	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.2	GO:0032009	early phagosome(GO:0032009)
0.0	1.0	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	1.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.6	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.5	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.2	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.9	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4	1.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	1.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2	0.6	GO:0016652	NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2	0.9	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2	1.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	2.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	0.5	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2	1.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	3.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.9	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	1.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.3	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1	0.3	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.1	0.7	GO:0003713	transcription coactivator activity(GO:0003713)
0.1	0.3	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.1	0.3	GO:0030626	U12 snRNA binding(GO:0030626)
0.1	0.5	GO:0044594	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1	0.4	GO:0015616	DNA translocase activity(GO:0015616)
0.1	0.5	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.6	GO:0016403	dimethylargininase activity(GO:0016403)
0.1	0.9	GO:0051434	BH3 domain binding(GO:0051434)
0.1	2.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	2.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.4	GO:0042806	fucose binding(GO:0042806)
0.1	1.9	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.2	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.1	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	0.7	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	0.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.5	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.2	GO:0004743	pyruvate kinase activity(GO:0004743)
0.0	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.3	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	0.3	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.3	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.5	GO:0000150	recombinase activity(GO:0000150)
0.0	0.4	GO:0042731	PH domain binding(GO:0042731)
0.0	0.2	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0	1.3	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.2	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.5	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.9	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	5.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	1.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	3.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	1.0	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0033265	choline binding(GO:0033265)
0.0	0.5	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.0	1.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.4	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	1.8	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.0	0.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.8	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.2	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.0	2.1	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.9	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.4	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0035473	lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0047708	biotinidase activity(GO:0047708)
0.0	0.7	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	2.6	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.8	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.2	GO:0005537	mannose binding(GO:0005537)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.8	GO:0003924	GTPase activity(GO:0003924)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	1.3	GO:0004222	metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.2	NABA COLLAGENS	Genes encoding collagen proteins
0.1	4.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	1.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.5	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	1.8	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	1.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	4.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	1.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.7	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.4	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.5	PID ARF6 PATHWAY	Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	9.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	2.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.7	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	2.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	1.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.8	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	1.0	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	3.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis