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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NHLH1

Z-value: 1.09

Motif logo

Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
ENSG00000171786.5 NHLH1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg19_v2_chr1_+_160336851_160336868-0.403.3e-01Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_39274606 2.88 ENST00000391413.2
KRTAP4-11
keratin associated protein 4-11
chr12_-_52887034 2.11 ENST00000330722.6
KRT6A
keratin 6A
chr17_-_39280419 2.07 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr12_-_52867569 1.64 ENST00000252250.6
KRT6C
keratin 6C
chr5_+_52776228 1.57 ENST00000256759.3
FST
follistatin
chr5_+_52776449 1.54 ENST00000396947.3
FST
follistatin
chr20_+_58179582 1.52 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr16_+_23847267 1.47 ENST00000321728.7
PRKCB
protein kinase C, beta
chr16_+_22825475 1.41 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr5_+_167181917 1.31 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr6_+_30848557 1.30 ENST00000460944.2
ENST00000324771.8
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_+_150464155 1.27 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr1_-_38273840 1.26 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr8_-_125740514 1.11 ENST00000325064.5
ENST00000518547.1
MTSS1
metastasis suppressor 1
chr16_+_68771128 1.10 ENST00000261769.5
ENST00000422392.2
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr20_+_20348740 1.08 ENST00000310227.1
INSM1
insulinoma-associated 1
chr2_-_31360887 1.01 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr9_-_23825956 0.98 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr20_+_44637526 0.95 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr5_-_1882858 0.93 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr22_+_40390930 0.89 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr8_+_86376081 0.86 ENST00000285379.5
CA2
carbonic anhydrase II
chr1_+_13910479 0.84 ENST00000509009.1
PDPN
podoplanin
chr11_+_394196 0.82 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr17_-_34122596 0.81 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr14_-_61748550 0.80 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr19_+_38755203 0.79 ENST00000587090.1
ENST00000454580.3
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_45281118 0.78 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr12_-_67072714 0.77 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
GRIP1
glutamate receptor interacting protein 1
chr22_+_45098067 0.77 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
PRR5
PRR5-ARHGAP8
proline rich 5 (renal)
PRR5-ARHGAP8 readthrough
chr4_-_80994210 0.76 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr2_+_69001913 0.75 ENST00000409030.3
ENST00000409220.1
ARHGAP25
Rho GTPase activating protein 25
chr19_+_38755042 0.74 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr2_-_96811170 0.72 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr1_-_209979465 0.71 ENST00000542854.1
IRF6
interferon regulatory factor 6
chr2_+_198570081 0.70 ENST00000282276.6
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr8_+_24771265 0.69 ENST00000518131.1
ENST00000437366.2
NEFM
neurofilament, medium polypeptide
chr20_-_14318248 0.68 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr8_+_24772455 0.67 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr1_+_13910194 0.65 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr17_-_31204124 0.65 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
MYO1D
myosin ID
chr12_+_122064673 0.64 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr1_+_60280458 0.63 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chr4_+_75310851 0.63 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr4_+_75311019 0.62 ENST00000502307.1
AREG
amphiregulin
chr1_+_3388181 0.62 ENST00000418137.1
ENST00000413250.2
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr16_+_57673207 0.62 ENST00000564783.1
ENST00000564729.1
ENST00000565976.1
ENST00000566508.1
ENST00000544297.1
GPR56
G protein-coupled receptor 56
chr7_+_20370300 0.61 ENST00000537992.1
ITGB8
integrin, beta 8
chr4_+_89299994 0.59 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr1_-_209979375 0.58 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr15_+_74833518 0.58 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr16_+_67465016 0.57 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr14_-_54423529 0.57 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr9_-_23826298 0.56 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr12_-_54779511 0.56 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr1_+_156254070 0.54 ENST00000405535.2
ENST00000456810.1
TMEM79
transmembrane protein 79
chr22_-_37882395 0.54 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_89299885 0.53 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr11_-_17035943 0.52 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr7_+_128784712 0.51 ENST00000289407.4
TSPAN33
tetraspanin 33
chr15_+_40650408 0.51 ENST00000267889.3
DISP2
dispatched homolog 2 (Drosophila)
chr1_+_233749739 0.50 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr22_+_45072925 0.49 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr22_+_45072958 0.48 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr16_+_3014217 0.48 ENST00000572045.1
KREMEN2
kringle containing transmembrane protein 2
chr2_+_196521845 0.48 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_-_39306054 0.48 ENST00000343246.4
KRTAP4-5
keratin associated protein 4-5
chr6_+_30851840 0.48 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_-_235405168 0.48 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr9_-_126030817 0.48 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP
spermatid perinuclear RNA binding protein
chr4_-_139163491 0.47 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_+_122459757 0.46 ENST00000261822.4
BCL7A
B-cell CLL/lymphoma 7A
chrX_-_84634737 0.46 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr17_+_47653178 0.46 ENST00000328741.5
NXPH3
neurexophilin 3
chr5_+_56111361 0.44 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr1_-_6662919 0.44 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr16_+_23847339 0.43 ENST00000303531.7
PRKCB
protein kinase C, beta
chr12_-_95044309 0.43 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chrX_-_117250740 0.43 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
KLHL13
kelch-like family member 13
chr8_-_144897549 0.43 ENST00000356994.2
ENST00000320476.3
SCRIB
scribbled planar cell polarity protein
chr17_+_80693427 0.42 ENST00000300784.7
FN3K
fructosamine 3 kinase
chr1_+_955448 0.42 ENST00000379370.2
AGRN
agrin
chr17_-_17109579 0.42 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr17_+_55162453 0.42 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr17_-_39254391 0.40 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr17_-_39324424 0.40 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr8_-_38008783 0.40 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr8_-_144897138 0.40 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr17_+_73512594 0.40 ENST00000333213.6
TSEN54
TSEN54 tRNA splicing endonuclease subunit
chr12_+_7055767 0.39 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr8_+_98788003 0.39 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr12_+_110152033 0.39 ENST00000538780.1
FAM222A
family with sequence similarity 222, member A
chr16_+_3014269 0.39 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
KREMEN2
kringle containing transmembrane protein 2
chr5_-_16936340 0.39 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr8_+_98788057 0.38 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr1_+_156124162 0.38 ENST00000368282.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_-_73511559 0.38 ENST00000521871.1
FBXO41
F-box protein 41
chr2_-_72375167 0.37 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr6_-_30712313 0.36 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr9_-_117880477 0.36 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC
tenascin C
chr17_-_39296739 0.35 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr4_-_80994619 0.35 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr1_+_65210772 0.35 ENST00000371072.4
ENST00000294428.3
RAVER2
ribonucleoprotein, PTB-binding 2
chr12_+_122064398 0.35 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr3_-_45187843 0.35 ENST00000296129.1
ENST00000425231.2
CDCP1
CUB domain containing protein 1
chr19_-_38743878 0.35 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr14_+_23842018 0.34 ENST00000397242.2
ENST00000329715.2
IL25
interleukin 25
chr9_+_101569944 0.34 ENST00000375011.3
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr6_+_4776580 0.34 ENST00000397588.3
CDYL
chromodomain protein, Y-like
chr2_+_48541776 0.34 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr4_+_154387480 0.33 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr3_-_33700933 0.33 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr8_+_128748308 0.32 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr12_+_50017327 0.32 ENST00000261897.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr1_+_15272271 0.32 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr7_+_150811705 0.31 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr2_+_196521458 0.31 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr12_+_7055631 0.31 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_+_161692449 0.30 ENST00000367946.3
ENST00000367945.1
ENST00000336830.5
ENST00000367944.3
ENST00000392158.1
FCRLB
Fc receptor-like B
chr4_-_80994471 0.30 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr1_+_90286562 0.29 ENST00000525774.1
ENST00000337338.5
LRRC8D
leucine rich repeat containing 8 family, member D
chr19_+_17858509 0.29 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr1_+_90287480 0.29 ENST00000394593.3
LRRC8D
leucine rich repeat containing 8 family, member D
chr1_+_32538492 0.29 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr1_+_33207381 0.29 ENST00000401073.2
KIAA1522
KIAA1522
chr19_-_17445613 0.29 ENST00000159087.4
ANO8
anoctamin 8
chr2_+_231577532 0.28 ENST00000258418.5
CAB39
calcium binding protein 39
chr12_+_50017184 0.28 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr16_-_90085824 0.28 ENST00000002501.6
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr11_+_66886717 0.28 ENST00000398645.2
KDM2A
lysine (K)-specific demethylase 2A
chr1_+_20915409 0.28 ENST00000375071.3
CDA
cytidine deaminase
chr20_+_49348081 0.27 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr10_+_71211212 0.27 ENST00000373290.2
TSPAN15
tetraspanin 15
chr2_+_65663812 0.26 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr4_+_30723003 0.26 ENST00000543491.1
PCDH7
protocadherin 7
chr1_+_32538520 0.26 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr16_+_2867164 0.26 ENST00000455114.1
ENST00000450020.3
PRSS21
protease, serine, 21 (testisin)
chr1_-_226496898 0.26 ENST00000481685.1
LIN9
lin-9 homolog (C. elegans)
chr18_+_43914159 0.26 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr2_+_103236004 0.26 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr6_-_43337180 0.25 ENST00000318149.3
ENST00000361428.2
ZNF318
zinc finger protein 318
chr1_+_27022839 0.25 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr7_-_138720763 0.25 ENST00000275766.1
ZC3HAV1L
zinc finger CCCH-type, antiviral 1-like
chr2_+_131100423 0.24 ENST00000409935.1
ENST00000409649.1
ENST00000428740.1
IMP4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr2_+_131100710 0.24 ENST00000452955.1
IMP4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr16_+_69373661 0.24 ENST00000254941.6
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr14_-_100070363 0.24 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr14_+_70346125 0.24 ENST00000361956.3
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr1_-_19536744 0.24 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr7_-_25702669 0.24 ENST00000446840.1
AC003090.1
AC003090.1
chr22_-_24989014 0.24 ENST00000318753.8
FAM211B
family with sequence similarity 211, member B
chr19_-_55954230 0.24 ENST00000376325.4
SHISA7
shisa family member 7
chr12_+_57984965 0.24 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr2_+_191045656 0.24 ENST00000443551.2
C2orf88
chromosome 2 open reading frame 88
chr2_+_128403439 0.23 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr19_+_17858547 0.23 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCHO1
FCH domain only 1
chr9_-_34376851 0.23 ENST00000297625.7
KIAA1161
KIAA1161
chr15_-_34629922 0.23 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr10_+_123923105 0.23 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr10_+_123922941 0.23 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr14_-_24732403 0.23 ENST00000206765.6
TGM1
transglutaminase 1
chr13_+_34392185 0.23 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr21_+_34442439 0.23 ENST00000382348.1
ENST00000333063.5
OLIG1
oligodendrocyte transcription factor 1
chr18_-_28742813 0.23 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr16_+_69373323 0.23 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr22_-_37823468 0.23 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr19_+_38810447 0.23 ENST00000263372.3
KCNK6
potassium channel, subfamily K, member 6
chr10_+_123923205 0.22 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr6_-_43543702 0.22 ENST00000265351.7
XPO5
exportin 5
chr15_+_50474412 0.22 ENST00000380902.4
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr11_-_65374430 0.22 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr1_+_27022485 0.22 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr15_+_50474385 0.22 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr7_-_138666053 0.22 ENST00000440172.1
ENST00000422774.1
KIAA1549
KIAA1549
chrX_-_84634708 0.22 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr7_-_148725733 0.22 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr1_-_177134024 0.22 ENST00000367654.3
ASTN1
astrotactin 1
chr19_-_17559376 0.22 ENST00000341130.5
TMEM221
transmembrane protein 221
chr16_+_1756162 0.21 ENST00000250894.4
ENST00000356010.5
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr16_+_75033210 0.21 ENST00000566250.1
ENST00000567962.1
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr12_-_86650045 0.21 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_+_75074385 0.21 ENST00000220003.9
CSK
c-src tyrosine kinase
chr17_-_56565736 0.21 ENST00000323777.3
HSF5
heat shock transcription factor family member 5
chrX_-_153285395 0.21 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr12_+_27932803 0.21 ENST00000381271.2
KLHL42
kelch-like family member 42
chr6_+_159290917 0.21 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr10_-_101380121 0.21 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr7_-_128045984 0.20 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr13_-_42535214 0.20 ENST00000379310.3
ENST00000281496.6
VWA8
von Willebrand factor A domain containing 8
chrX_-_153285251 0.20 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr14_-_24732368 0.20 ENST00000544573.1
TGM1
transglutaminase 1
chr7_-_767249 0.20 ENST00000403562.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr3_+_124303539 0.20 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr1_+_28918712 0.20 ENST00000373826.3
RAB42
RAB42, member RAS oncogene family
chr2_+_191045562 0.20 ENST00000340623.4
C2orf88
chromosome 2 open reading frame 88
chr6_-_33756867 0.20 ENST00000293760.5
LEMD2
LEM domain containing 2
chr15_-_53082178 0.20 ENST00000305901.5
ONECUT1
one cut homeobox 1
chr16_+_22217577 0.20 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr8_+_142138799 0.20 ENST00000518668.1
DENND3
DENN/MADD domain containing 3
chr15_+_75074410 0.19 ENST00000439220.2
CSK
c-src tyrosine kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.5 2.1 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.5 1.5 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.5 1.4 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.4 1.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.3 3.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.5 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 0.9 GO:0042938 dipeptide transport(GO:0042938)
0.3 0.8 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.2 0.8 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.6 GO:0061151 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.1 GO:0030035 microspike assembly(GO:0030035)
0.2 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 0.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 0.5 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.2 1.1 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.2 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.2 1.3 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.4 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.9 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.4 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.1 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) negative regulation of neuromuscular junction development(GO:1904397)
0.1 1.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.6 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.4 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.5 GO:0042335 cuticle development(GO:0042335)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.2 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 1.3 GO:0097264 self proteolysis(GO:0097264)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.4 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.7 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.3 GO:0009624 response to nematode(GO:0009624)
0.1 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.2 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.2 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 6.4 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.2 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.3 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 1.3 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.6 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 1.3 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0001525 angiogenesis(GO:0001525)
0.0 0.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.0 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.0 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124) regulation of GTP binding(GO:1904424)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.6 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 10.2 GO:0045095 keratin filament(GO:0045095)
0.1 1.1 GO:0016342 catenin complex(GO:0016342)
0.1 0.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 1.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.2 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.1 GO:0070820 tertiary granule(GO:0070820) tertiary granule membrane(GO:0070821)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 2.0 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 1.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.4 1.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 2.2 GO:0048185 activin binding(GO:0048185)
0.1 1.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.9 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0070700 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 1.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.0 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.8 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB