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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NKX2-2

Z-value: 0.61

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Transcription factors associated with NKX2-2

Gene Symbol Gene ID Gene Info
NKX2-2
ENSG00000125820.5 NKX2-2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-2hg19_v2_chr20_-_21494654_214946780.196.5e-01Click!

Activity profile of NKX2-2 motif

Sorted Z-values of NKX2-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_78769549 0.62 ENST00000370758.1
 PTGFR
 prostaglandin F receptor (FP)
chr21_+_25801041 0.62 ENST00000453784.2
ENST00000423581.1
 AP000476.1
 AP000476.1
chr8_+_97597148 0.61 ENST00000521590.1
 SDC2
 syndecan 2
chr4_-_156787425 0.60 ENST00000537611.2
 ASIC5
 acid-sensing (proton-gated) ion channel family member 5
chr5_+_82767583 0.56 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
 VCAN
 versican
chr5_+_82767487 0.54 ENST00000343200.5
ENST00000342785.4
 VCAN
 versican
chr13_+_102104980 0.54 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr8_-_122653630 0.53 ENST00000303924.4
 HAS2
 hyaluronan synthase 2
chr13_+_102104952 0.50 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr2_-_238323007 0.47 ENST00000295550.4
 COL6A3
 collagen, type VI, alpha 3
chr6_+_151561085 0.42 ENST00000402676.2
 AKAP12
 A kinase (PRKA) anchor protein 12
chr2_+_152214098 0.42 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr13_-_67802549 0.40 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr17_-_67138015 0.39 ENST00000284425.2
ENST00000590645.1
 ABCA6
 ATP-binding cassette, sub-family A (ABC1), member 6
chr8_+_77593448 0.36 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr17_-_29641104 0.29 ENST00000577894.1
ENST00000330927.4
 EVI2B
 ecotropic viral integration site 2B
chr8_+_77593474 0.27 ENST00000455469.2
ENST00000050961.6
 ZFHX4
 zinc finger homeobox 4
chr4_-_99578789 0.27 ENST00000511651.1
ENST00000505184.1
 TSPAN5
 tetraspanin 5
chr16_+_53241854 0.27 ENST00000565803.1
 CHD9
 chromodomain helicase DNA binding protein 9
chrX_+_100743031 0.26 ENST00000423738.3
 ARMCX4
 armadillo repeat containing, X-linked 4
chr3_+_142838091 0.26 ENST00000309575.3
 CHST2
 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr2_-_214014959 0.25 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
 IKZF2
 IKAROS family zinc finger 2 (Helios)
chrM_+_12331 0.25 ENST00000361567.2
 MT-ND5
 mitochondrially encoded NADH dehydrogenase 5
chr5_-_150521192 0.24 ENST00000523714.1
ENST00000521749.1
 ANXA6
 annexin A6
chr9_-_21482312 0.23 ENST00000448696.3
 IFNE
 interferon, epsilon
chrX_-_70474377 0.21 ENST00000373978.1
ENST00000373981.1
 ZMYM3
 zinc finger, MYM-type 3
chr9_-_20622478 0.20 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr17_-_29641084 0.20 ENST00000544462.1
 EVI2B
 ecotropic viral integration site 2B
chr2_+_152266604 0.20 ENST00000430328.2
 RIF1
 RAP1 interacting factor homolog (yeast)
chr4_+_114214125 0.20 ENST00000509550.1
 ANK2
 ankyrin 2, neuronal
chr12_-_120315074 0.20 ENST00000261833.7
ENST00000392521.2
 CIT
 citron (rho-interacting, serine/threonine kinase 21)
chr10_+_89420706 0.20 ENST00000427144.2
 PAPSS2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_-_145275228 0.19 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr13_+_50570019 0.19 ENST00000442421.1
 TRIM13
 tripartite motif containing 13
chr1_+_211433275 0.19 ENST00000367005.4
 RCOR3
 REST corepressor 3
chr1_-_227505289 0.19 ENST00000366765.3
 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
chr4_-_99578776 0.19 ENST00000515287.1
 TSPAN5
 tetraspanin 5
chr1_+_162602244 0.19 ENST00000367922.3
ENST00000367921.3
 DDR2
 discoidin domain receptor tyrosine kinase 2
chr6_+_151561506 0.18 ENST00000253332.1
 AKAP12
 A kinase (PRKA) anchor protein 12
chr1_+_104293028 0.18 ENST00000370079.3
 AMY1C
 amylase, alpha 1C (salivary)
chr18_-_70532906 0.17 ENST00000299430.2
ENST00000397929.1
 NETO1
 neuropilin (NRP) and tolloid (TLL)-like 1
chr4_+_124320665 0.17 ENST00000394339.2
 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr5_-_78281603 0.17 ENST00000264914.4
 ARSB
 arylsulfatase B
chr15_-_52944231 0.16 ENST00000546305.2
 FAM214A
 family with sequence similarity 214, member A
chr6_+_28249299 0.16 ENST00000405948.2
 PGBD1
 piggyBac transposable element derived 1
chr6_+_28249332 0.16 ENST00000259883.3
 PGBD1
 piggyBac transposable element derived 1
chr12_-_49582978 0.15 ENST00000301071.7
 TUBA1A
 tubulin, alpha 1a
chr13_+_111766897 0.15 ENST00000317133.5
 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_104159999 0.15 ENST00000414303.2
ENST00000423678.1
 AMY2A
 amylase, alpha 2A (pancreatic)
chr3_+_189507460 0.15 ENST00000434928.1
 TP63
 tumor protein p63
chr12_-_10978957 0.15 ENST00000240619.2
 TAS2R10
 taste receptor, type 2, member 10
chr3_+_63953415 0.14 ENST00000484332.1
 ATXN7
 ataxin 7
chr5_+_140602904 0.14 ENST00000515856.2
ENST00000239449.4
 PCDHB14
 protocadherin beta 14
chr1_-_159880159 0.14 ENST00000599780.1
 AL590560.1
 HCG1995379; Uncharacterized protein
chr9_+_37667978 0.14 ENST00000539465.1
 FRMPD1
 FERM and PDZ domain containing 1
chrX_-_70473957 0.14 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
 ZMYM3
 zinc finger, MYM-type 3
chr4_+_113739244 0.14 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
 ANK2
 ankyrin 2, neuronal
chr14_-_82000140 0.14 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
 SEL1L
 sel-1 suppressor of lin-12-like (C. elegans)
chr12_-_102591604 0.13 ENST00000329406.4
 PMCH
 pro-melanin-concentrating hormone
chr15_-_56209306 0.13 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr17_+_42264322 0.13 ENST00000446571.3
ENST00000357984.3
ENST00000538716.2
 TMUB2
 transmembrane and ubiquitin-like domain containing 2
chr4_-_119759795 0.13 ENST00000419654.2
 SEC24D
 SEC24 family member D
chr12_+_52056548 0.13 ENST00000545061.1
ENST00000355133.3
 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
chr20_+_30102231 0.13 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
 HM13
 histocompatibility (minor) 13
chr7_-_92855762 0.12 ENST00000453812.2
ENST00000394468.2
 HEPACAM2
 HEPACAM family member 2
chr2_-_40739501 0.12 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
chr11_-_124981475 0.12 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
 TMEM218
 transmembrane protein 218
chr3_-_150920979 0.12 ENST00000309180.5
ENST00000480322.1
 GPR171
 G protein-coupled receptor 171
chr11_+_65266507 0.12 ENST00000544868.1
 MALAT1
 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr9_+_99690592 0.12 ENST00000354649.3
 NUTM2G
 NUT family member 2G
chr8_-_133772794 0.12 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
 TMEM71
 transmembrane protein 71
chr16_+_22501658 0.11 ENST00000415833.2
 NPIPB5
 nuclear pore complex interacting protein family, member B5
chr17_-_8059638 0.11 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
 PER1
 period circadian clock 1
chrX_-_70474499 0.11 ENST00000353904.2
 ZMYM3
 zinc finger, MYM-type 3
chr13_-_107220455 0.11 ENST00000400198.3
 ARGLU1
 arginine and glutamate rich 1
chrX_-_30326445 0.11 ENST00000378963.1
 NR0B1
 nuclear receptor subfamily 0, group B, member 1
chr10_+_124670121 0.11 ENST00000368894.1
 FAM24A
 family with sequence similarity 24, member A
chr15_-_60690163 0.11 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
 ANXA2
 annexin A2
chr3_-_122134882 0.11 ENST00000330689.4
 WDR5B
 WD repeat domain 5B
chr8_-_62559366 0.10 ENST00000522919.1
 ASPH
 aspartate beta-hydroxylase
chr17_-_2966901 0.10 ENST00000575751.1
 OR1D5
 olfactory receptor, family 1, subfamily D, member 5
chr7_+_150065278 0.10 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
 REPIN1
 replication initiator 1
chr9_-_139361503 0.10 ENST00000453963.1
 SEC16A
 SEC16 homolog A (S. cerevisiae)
chr11_+_94277017 0.10 ENST00000358752.2
 FUT4
 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr5_-_58335281 0.10 ENST00000358923.6
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr4_+_36283213 0.10 ENST00000357504.3
 DTHD1
 death domain containing 1
chr5_+_140800638 0.10 ENST00000398587.2
ENST00000518882.1
 PCDHGA11
 protocadherin gamma subfamily A, 11
chrX_+_47092314 0.10 ENST00000218348.3
 USP11
 ubiquitin specific peptidase 11
chr15_-_56757329 0.10 ENST00000260453.3
 MNS1
 meiosis-specific nuclear structural 1
chr6_-_116833500 0.10 ENST00000356128.4
 TRAPPC3L
 trafficking protein particle complex 3-like
chr2_+_170655322 0.09 ENST00000260956.4
ENST00000417292.1
 SSB
 Sjogren syndrome antigen B (autoantigen La)
chr19_-_39881669 0.09 ENST00000221266.7
 PAF1
 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr22_-_24093267 0.09 ENST00000341976.3
 ZNF70
 zinc finger protein 70
chr17_+_48823896 0.09 ENST00000511974.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr11_+_93479588 0.09 ENST00000526335.1
 C11orf54
 chromosome 11 open reading frame 54
chr7_-_102715263 0.09 ENST00000379305.3
 FBXL13
 F-box and leucine-rich repeat protein 13
chr15_+_69365265 0.09 ENST00000415504.1
 LINC00277
 long intergenic non-protein coding RNA 277
chr2_+_152266392 0.09 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
 RIF1
 RAP1 interacting factor homolog (yeast)
chrX_+_34960907 0.09 ENST00000329357.5
 FAM47B
 family with sequence similarity 47, member B
chr12_+_109826524 0.09 ENST00000431443.2
 MYO1H
 myosin IH
chr15_+_65843130 0.09 ENST00000569894.1
 PTPLAD1
 protein tyrosine phosphatase-like A domain containing 1
chr10_+_13203543 0.09 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
 MCM10
 minichromosome maintenance complex component 10
chr2_+_201994569 0.09 ENST00000457277.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chrX_+_83116142 0.09 ENST00000329312.4
 CYLC1
 cylicin, basic protein of sperm head cytoskeleton 1
chr1_-_54405773 0.09 ENST00000371376.1
 HSPB11
 heat shock protein family B (small), member 11
chr11_-_77850629 0.09 ENST00000376156.3
ENST00000525870.1
ENST00000530454.1
ENST00000525755.1
ENST00000527099.1
ENST00000525761.1
ENST00000299626.5
 ALG8
 ALG8, alpha-1,3-glucosyltransferase
chr5_+_108083517 0.09 ENST00000281092.4
ENST00000536402.1
 FER
 fer (fps/fes related) tyrosine kinase
chrX_-_19817869 0.09 ENST00000379698.4
 SH3KBP1
 SH3-domain kinase binding protein 1
chr8_+_71485681 0.08 ENST00000391684.1
 AC120194.1
 AC120194.1
chr2_+_189157498 0.08 ENST00000359135.3
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr6_-_27440460 0.08 ENST00000377419.1
 ZNF184
 zinc finger protein 184
chrX_+_36053908 0.08 ENST00000378660.2
 CHDC2
 calponin homology domain containing 2
chr7_-_120497178 0.08 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
 TSPAN12
 tetraspanin 12
chr5_-_110848189 0.08 ENST00000296632.3
ENST00000512160.1
ENST00000509887.1
 STARD4
 StAR-related lipid transfer (START) domain containing 4
chr3_-_33686925 0.08 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
 CLASP2
 cytoplasmic linker associated protein 2
chr19_-_44174305 0.08 ENST00000601723.1
ENST00000339082.3
 PLAUR
 plasminogen activator, urokinase receptor
chr9_+_71819927 0.08 ENST00000535702.1
 TJP2
 tight junction protein 2
chr9_-_15510287 0.08 ENST00000397519.2
 PSIP1
 PC4 and SFRS1 interacting protein 1
chr7_-_102715172 0.07 ENST00000456695.1
ENST00000455112.2
ENST00000440067.1
 FBXL13
 F-box and leucine-rich repeat protein 13
chr3_-_69101461 0.07 ENST00000543976.1
 TMF1
 TATA element modulatory factor 1
chr2_+_189157536 0.07 ENST00000409580.1
ENST00000409637.3
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr10_-_27529486 0.07 ENST00000375888.1
 ACBD5
 acyl-CoA binding domain containing 5
chrX_-_70474910 0.07 ENST00000373988.1
ENST00000373998.1
 ZMYM3
 zinc finger, MYM-type 3
chr20_+_56964169 0.07 ENST00000475243.1
 VAPB
 VAMP (vesicle-associated membrane protein)-associated protein B and C
chr5_-_11588907 0.07 ENST00000513598.1
ENST00000503622.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr20_+_18488137 0.07 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
 SEC23B
 Sec23 homolog B (S. cerevisiae)
chrX_+_115567767 0.07 ENST00000371900.4
 SLC6A14
 solute carrier family 6 (amino acid transporter), member 14
chr9_+_71820057 0.07 ENST00000539225.1
 TJP2
 tight junction protein 2
chr1_-_115238207 0.07 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
 AMPD1
 adenosine monophosphate deaminase 1
chr14_-_50154921 0.07 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
 POLE2
 polymerase (DNA directed), epsilon 2, accessory subunit
chr4_+_88720698 0.07 ENST00000226284.5
 IBSP
 integrin-binding sialoprotein
chr3_+_159943362 0.07 ENST00000326474.3
 C3orf80
 chromosome 3 open reading frame 80
chr20_-_13765526 0.07 ENST00000202816.1
 ESF1
 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr5_+_135394840 0.07 ENST00000503087.1
 TGFBI
 transforming growth factor, beta-induced, 68kDa
chr4_+_56719782 0.06 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
 EXOC1
 exocyst complex component 1
chr13_-_61989655 0.06 ENST00000409204.4
 PCDH20
 protocadherin 20
chr12_-_71551652 0.06 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr2_+_201994208 0.06 ENST00000440180.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr5_+_56205878 0.06 ENST00000423328.1
 SETD9
 SET domain containing 9
chr19_-_14889349 0.06 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
 EMR2
 egf-like module containing, mucin-like, hormone receptor-like 2
chr17_-_43339474 0.06 ENST00000331780.4
 SPATA32
 spermatogenesis associated 32
chr1_+_158901329 0.06 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
 PYHIN1
 pyrin and HIN domain family, member 1
chr1_-_169429690 0.06 ENST00000445428.1
 RP1-206D15.3
 RP1-206D15.3
chr7_+_93535817 0.06 ENST00000248572.5
 GNGT1
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr10_+_63808970 0.06 ENST00000309334.5
 ARID5B
 AT rich interactive domain 5B (MRF1-like)
chr2_-_24270217 0.06 ENST00000295148.4
ENST00000406895.3
 C2orf44
 chromosome 2 open reading frame 44
chr1_+_104068312 0.06 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
 RNPC3
 RNA-binding region (RNP1, RRM) containing 3
chrM_+_4431 0.06 ENST00000361453.3
 MT-ND2
 mitochondrially encoded NADH dehydrogenase 2
chr12_-_111926342 0.06 ENST00000389154.3
 ATXN2
 ataxin 2
chr11_+_22689648 0.06 ENST00000278187.3
 GAS2
 growth arrest-specific 2
chr2_-_163008903 0.06 ENST00000418842.2
ENST00000375497.3
 GCG
 glucagon
chr2_-_55276320 0.05 ENST00000357376.3
 RTN4
 reticulon 4
chr12_-_4488872 0.05 ENST00000237837.1
 FGF23
 fibroblast growth factor 23
chr14_+_94547628 0.05 ENST00000555523.1
 IFI27L1
 interferon, alpha-inducible protein 27-like 1
chr14_+_94547675 0.05 ENST00000393115.3
ENST00000554166.1
ENST00000556381.1
ENST00000553664.1
ENST00000555341.1
ENST00000557218.1
ENST00000554544.1
ENST00000557066.1
 IFI27L1
 interferon, alpha-inducible protein 27-like 1
chr5_+_148206156 0.05 ENST00000305988.4
 ADRB2
 adrenoceptor beta 2, surface
chr9_-_39239171 0.05 ENST00000358144.2
 CNTNAP3
 contactin associated protein-like 3
chr7_+_32535060 0.05 ENST00000318709.4
ENST00000409301.1
ENST00000404479.1
 AVL9
 AVL9 homolog (S. cerevisiase)
chr9_+_37753795 0.05 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
 TRMT10B
 tRNA methyltransferase 10 homolog B (S. cerevisiae)
chr22_+_42086547 0.05 ENST00000402966.1
 C22orf46
 chromosome 22 open reading frame 46
chr16_+_30212378 0.05 ENST00000569485.1
 SULT1A3
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_-_202936394 0.05 ENST00000367249.4
 CYB5R1
 cytochrome b5 reductase 1
chr6_+_55039050 0.05 ENST00000370862.3
 HCRTR2
 hypocretin (orexin) receptor 2
chr19_-_17366257 0.05 ENST00000594059.1
 AC010646.3
 Uncharacterized protein
chr21_+_30968360 0.05 ENST00000333765.4
 GRIK1-AS2
 GRIK1 antisense RNA 2
chr7_-_99149715 0.05 ENST00000449309.1
 FAM200A
 family with sequence similarity 200, member A
chr5_-_148033726 0.05 ENST00000354217.2
ENST00000314512.6
ENST00000362016.2
 HTR4
 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr19_-_44174330 0.05 ENST00000340093.3
 PLAUR
 plasminogen activator, urokinase receptor
chr15_+_54305101 0.05 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
 UNC13C
 unc-13 homolog C (C. elegans)
chr17_-_15469590 0.05 ENST00000312127.2
 CDRT1
 CMT duplicated region transcript 1; Uncharacterized protein
chr9_-_97356075 0.05 ENST00000375337.3
 FBP2
 fructose-1,6-bisphosphatase 2
chr6_-_150067632 0.05 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
 NUP43
 nucleoporin 43kDa
chr1_-_213188772 0.04 ENST00000544555.1
 ANGEL2
 angel homolog 2 (Drosophila)
chr4_+_158493642 0.04 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
 RP11-364P22.1
 RP11-364P22.1
chr17_+_48823975 0.04 ENST00000513969.1
ENST00000503728.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr2_+_113299990 0.04 ENST00000537335.1
ENST00000417433.2
 POLR1B
 polymerase (RNA) I polypeptide B, 128kDa
chr5_-_139937895 0.04 ENST00000336283.6
 SRA1
 steroid receptor RNA activator 1
chr5_-_98262240 0.04 ENST00000284049.3
 CHD1
 chromodomain helicase DNA binding protein 1
chr9_+_125132803 0.04 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_+_183770835 0.04 ENST00000318351.1
 HTR3C
 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
chr5_-_148033693 0.04 ENST00000377888.3
ENST00000360693.3
 HTR4
 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr6_+_152130240 0.04 ENST00000427531.2
 ESR1
 estrogen receptor 1
chr6_+_158957431 0.04 ENST00000367090.3
 TMEM181
 transmembrane protein 181
chr8_+_11660120 0.04 ENST00000220584.4
 FDFT1
 farnesyl-diphosphate farnesyltransferase 1
chr10_+_13628933 0.04 ENST00000417658.1
ENST00000320054.4
 PRPF18
 pre-mRNA processing factor 18
chrX_-_19988382 0.04 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
 CXorf23
 chromosome X open reading frame 23
chr13_-_33112899 0.04 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
 N4BP2L2
 NEDD4 binding protein 2-like 2
chr2_+_79347577 0.04 ENST00000233735.1
 REG1A
 regenerating islet-derived 1 alpha
chr6_-_26027480 0.04 ENST00000377364.3
 HIST1H4B
 histone cluster 1, H4b
chr12_-_68696652 0.04 ENST00000539972.1
 MDM1
 Mdm1 nuclear protein homolog (mouse)
chr7_+_72742178 0.04 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
 FKBP6
 FK506 binding protein 6, 36kDa
chr1_+_84630053 0.04 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr5_-_11589131 0.04 ENST00000511377.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr20_-_41818373 0.04 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
 PTPRT
 protein tyrosine phosphatase, receptor type, T
chr3_-_69101413 0.04 ENST00000398559.2
 TMF1
 TATA element modulatory factor 1
chr4_+_41937131 0.04 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
 TMEM33
 transmembrane protein 33
chr10_-_14504093 0.04 ENST00000493380.1
ENST00000475141.2
 FRMD4A
 FERM domain containing 4A
chrX_-_39186610 0.04 ENST00000429281.1
ENST00000448597.1
 RP11-265P11.2
 RP11-265P11.2
chr14_-_77495007 0.04 ENST00000238647.3
 IRF2BPL
 interferon regulatory factor 2 binding protein-like
chr8_+_11666649 0.04 ENST00000528643.1
ENST00000525777.1
 FDFT1
 farnesyl-diphosphate farnesyltransferase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.6 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.3 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 1.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.1 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.1 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.4 GO:0030728 ovulation(GO:0030728)
0.0 0.0 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0097450 astrocyte end-foot(GO:0097450)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.2 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0016160 amylase activity(GO:0016160)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis