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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NR1I3

Z-value: 0.63

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
ENSG00000143257.7 NR1I3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161207986_1612080000.611.1e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_44401479 1.27 ENST00000438616.3
ARTN
artemin
chr6_+_36097992 1.17 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr15_+_43885252 1.01 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr14_+_21525981 1.00 ENST00000308227.2
RNASE8
ribonuclease, RNase A family, 8
chr15_+_43985084 0.98 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr1_+_153330322 0.97 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr13_-_20806440 0.96 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
GJB6
gap junction protein, beta 6, 30kDa
chr1_+_15250596 0.68 ENST00000361144.5
KAZN
kazrin, periplakin interacting protein
chr1_-_205290865 0.56 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr12_-_54779511 0.51 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr3_-_116163830 0.35 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr14_-_22005062 0.32 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr2_-_69180083 0.32 ENST00000328895.4
GKN2
gastrokine 2
chr1_-_23886285 0.28 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr14_+_22977587 0.27 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr2_-_69098566 0.26 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr2_-_69180012 0.25 ENST00000481498.1
GKN2
gastrokine 2
chr17_-_34270668 0.22 ENST00000293274.4
LYZL6
lysozyme-like 6
chr17_-_34270697 0.22 ENST00000585556.1
LYZL6
lysozyme-like 6
chr3_-_71802760 0.21 ENST00000295612.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr16_+_577697 0.21 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr11_+_63137251 0.18 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr19_-_49140609 0.17 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_44306590 0.16 ENST00000377950.3
LYPD5
LY6/PLAUR domain containing 5
chr11_-_59950519 0.16 ENST00000528851.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr7_-_31380502 0.15 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr14_-_22005018 0.15 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr20_+_57766075 0.15 ENST00000371030.2
ZNF831
zinc finger protein 831
chr9_+_5450503 0.14 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chrX_+_69674943 0.14 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr8_-_109799793 0.13 ENST00000297459.3
TMEM74
transmembrane protein 74
chr4_-_82136114 0.13 ENST00000395578.1
ENST00000418486.2
PRKG2
protein kinase, cGMP-dependent, type II
chr11_-_57089671 0.11 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr16_-_75018968 0.11 ENST00000262144.6
WDR59
WD repeat domain 59
chr10_-_50396425 0.11 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr18_-_19283649 0.11 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr20_-_44007014 0.11 ENST00000372726.3
ENST00000537995.1
TP53TG5
TP53 target 5
chr14_-_77787198 0.11 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr16_-_4465886 0.10 ENST00000539968.1
CORO7
coronin 7
chr3_-_116164306 0.10 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr11_+_105480740 0.10 ENST00000393125.2
GRIA4
glutamate receptor, ionotropic, AMPA 4
chr20_-_45142154 0.10 ENST00000347606.4
ENST00000457685.2
ZNF334
zinc finger protein 334
chrX_+_128872998 0.09 ENST00000371106.3
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr12_-_53729525 0.09 ENST00000303846.3
SP7
Sp7 transcription factor
chr3_+_122103014 0.09 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr12_-_118810688 0.08 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr18_-_19284724 0.08 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr19_+_676385 0.08 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chrX_-_110655391 0.08 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr6_+_32407619 0.08 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr9_+_37486005 0.08 ENST00000377792.3
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr6_-_43496605 0.07 ENST00000455285.2
XPO5
exportin 5
chr18_-_33077556 0.07 ENST00000589273.1
ENST00000586489.1
INO80C
INO80 complex subunit C
chr12_+_100594557 0.07 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr3_-_50396978 0.06 ENST00000266025.3
TMEM115
transmembrane protein 115
chr6_-_31509714 0.06 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chrX_-_15619076 0.06 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr2_+_220462560 0.06 ENST00000456909.1
ENST00000295641.10
STK11IP
serine/threonine kinase 11 interacting protein
chr6_+_33422343 0.06 ENST00000395064.2
ZBTB9
zinc finger and BTB domain containing 9
chr6_-_34113856 0.05 ENST00000538487.2
GRM4
glutamate receptor, metabotropic 4
chr13_-_95131923 0.05 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr8_-_53626974 0.05 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr6_+_71276596 0.05 ENST00000370474.3
C6orf57
chromosome 6 open reading frame 57
chr1_+_43803475 0.05 ENST00000372470.3
ENST00000413998.2
MPL
myeloproliferative leukemia virus oncogene
chr16_-_66968055 0.04 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr2_-_86790593 0.04 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr16_+_30710462 0.04 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr7_-_99381798 0.04 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr1_+_113217043 0.04 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_57320437 0.04 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr14_+_77787227 0.03 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr19_-_49140692 0.03 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr1_-_33336414 0.03 ENST00000373471.3
ENST00000609187.1
FNDC5
fibronectin type III domain containing 5
chr7_-_99381884 0.03 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr16_-_16317321 0.03 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr2_+_177015950 0.03 ENST00000306324.3
HOXD4
homeobox D4
chr17_-_62502639 0.02 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr6_+_108487245 0.02 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr2_-_128642434 0.02 ENST00000393001.1
AMMECR1L
AMMECR1-like
chr3_-_58419537 0.02 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr19_-_46296011 0.02 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr15_+_85523671 0.02 ENST00000310298.4
ENST00000557957.1
PDE8A
phosphodiesterase 8A
chr10_+_88414338 0.02 ENST00000241891.5
ENST00000443292.1
OPN4
opsin 4
chr16_+_67906919 0.02 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr19_+_58919992 0.02 ENST00000306910.4
ENST00000598901.1
ENST00000593920.1
ENST00000596281.1
ZNF584
zinc finger protein 584
chr1_-_151119087 0.01 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr19_+_12203069 0.01 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr6_+_96969672 0.01 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr16_-_66968265 0.00 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr10_-_50396407 0.00 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr13_-_21635631 0.00 ENST00000382592.4
LATS2
large tumor suppressor kinase 2
chr7_+_101460882 0.00 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr9_-_80646374 0.00 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 1.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.2 1.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.5 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.0 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.3 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.1 GO:0036378 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 1.0 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0030903 notochord development(GO:0030903)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression