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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NR2E3

Z-value: 1.45

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Transcription factors associated with NR2E3

Gene Symbol Gene ID Gene Info
NR2E3
ENSG00000031544.10 NR2E3

Activity profile of NR2E3 motif

Sorted Z-values of NR2E3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_60337684 3.65 ENST00000267484.5
 RTN1
 reticulon 1
chr13_+_102104980 3.43 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr13_+_102104952 3.09 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr7_+_94023873 2.30 ENST00000297268.6
 COL1A2
 collagen, type I, alpha 2
chr12_-_91539918 2.09 ENST00000548218.1
 DCN
 decorin
chr2_+_33359646 1.82 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr10_-_93392811 1.80 ENST00000238994.5
 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
chr2_+_33359687 1.79 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr2_-_145277569 1.70 ENST00000303660.4
 ZEB2
 zinc finger E-box binding homeobox 2
chr3_-_195310802 1.67 ENST00000421243.1
ENST00000453131.1
 APOD
 apolipoprotein D
chr2_-_145277640 1.67 ENST00000539609.3
 ZEB2
 zinc finger E-box binding homeobox 2
chr5_-_138210977 1.60 ENST00000274711.6
ENST00000521094.2
 LRRTM2
 leucine rich repeat transmembrane neuronal 2
chr14_-_61124977 1.51 ENST00000554986.1
 SIX1
 SIX homeobox 1
chr12_+_32655048 1.47 ENST00000427716.2
ENST00000266482.3
 FGD4
 FYVE, RhoGEF and PH domain containing 4
chr3_+_69915385 1.40 ENST00000314589.5
 MITF
 microphthalmia-associated transcription factor
chr13_+_76378357 1.35 ENST00000489941.2
ENST00000525373.1
 LMO7
 LIM domain 7
chr13_+_76334498 1.33 ENST00000534657.1
 LMO7
 LIM domain 7
chr9_-_95244781 1.31 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
 ASPN
 asporin
chr3_+_141043050 1.27 ENST00000509842.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr5_-_20575959 1.23 ENST00000507958.1
 CDH18
 cadherin 18, type 2
chr14_+_101297740 1.22 ENST00000555928.1
 MEG3
 maternally expressed 3 (non-protein coding)
chr2_-_202563414 1.22 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
 MPP4
 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr14_+_74035763 1.17 ENST00000238651.5
 ACOT2
 acyl-CoA thioesterase 2
chr5_-_150537279 1.15 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
 ANXA6
 annexin A6
chr2_+_152214098 1.13 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr10_+_31610064 1.12 ENST00000446923.2
ENST00000559476.1
 ZEB1
 zinc finger E-box binding homeobox 1
chr13_-_33780133 1.11 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr2_-_145278475 1.09 ENST00000558170.2
 ZEB2
 zinc finger E-box binding homeobox 2
chr9_+_91605778 1.09 ENST00000375851.2
ENST00000375850.3
ENST00000334490.5
 C9orf47
 chromosome 9 open reading frame 47
chr13_+_76334795 1.04 ENST00000526202.1
ENST00000465261.2
 LMO7
 LIM domain 7
chr3_+_141105235 1.04 ENST00000503809.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr14_+_74004051 1.02 ENST00000557556.1
 ACOT1
 acyl-CoA thioesterase 1
chr3_+_141105705 1.00 ENST00000513258.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr10_-_14372870 0.99 ENST00000357447.2
 FRMD4A
 FERM domain containing 4A
chr14_+_74003818 0.90 ENST00000311148.4
 ACOT1
 acyl-CoA thioesterase 1
chr1_+_215256467 0.87 ENST00000391894.2
ENST00000444842.2
 KCNK2
 potassium channel, subfamily K, member 2
chr3_-_156534754 0.86 ENST00000472943.1
ENST00000473352.1
 LINC00886
 long intergenic non-protein coding RNA 886
chr5_+_110559784 0.83 ENST00000282356.4
 CAMK4
 calcium/calmodulin-dependent protein kinase IV
chr16_+_86612112 0.80 ENST00000320241.3
 FOXL1
 forkhead box L1
chr12_+_53443963 0.79 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_61330931 0.75 ENST00000371191.1
 NFIA
 nuclear factor I/A
chr5_-_75919217 0.74 ENST00000504899.1
 F2RL2
 coagulation factor II (thrombin) receptor-like 2
chr13_+_76362974 0.73 ENST00000497947.2
 LMO7
 LIM domain 7
chr8_+_38677850 0.72 ENST00000518809.1
ENST00000520611.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr13_+_76334567 0.72 ENST00000321797.8
 LMO7
 LIM domain 7
chr5_+_110559603 0.71 ENST00000512453.1
 CAMK4
 calcium/calmodulin-dependent protein kinase IV
chr20_-_30310336 0.71 ENST00000434194.1
ENST00000376062.2
 BCL2L1
 BCL2-like 1
chr12_+_56661461 0.71 ENST00000546544.1
ENST00000553234.1
 COQ10A
 coenzyme Q10 homolog A (S. cerevisiae)
chr17_+_1633755 0.70 ENST00000545662.1
 WDR81
 WD repeat domain 81
chr2_-_175712270 0.68 ENST00000295497.7
ENST00000444394.1
 CHN1
 chimerin 1
chr1_+_221051699 0.68 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr1_+_65775204 0.67 ENST00000371069.4
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_76870126 0.67 ENST00000586057.1
 TIMP2
 TIMP metallopeptidase inhibitor 2
chr16_+_2039946 0.66 ENST00000248121.2
ENST00000568896.1
 SYNGR3
 synaptogyrin 3
chr2_-_3584430 0.66 ENST00000438482.1
ENST00000422961.1
 AC108488.4
 AC108488.4
chr17_+_68165657 0.64 ENST00000243457.3
 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
chr7_+_120702819 0.63 ENST00000423795.1
 CPED1
 cadherin-like and PC-esterase domain containing 1
chr12_+_51785057 0.62 ENST00000535225.2
 SLC4A8
 solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr1_+_61547405 0.62 ENST00000371189.4
 NFIA
 nuclear factor I/A
chr2_-_207082748 0.61 ENST00000407325.2
ENST00000411719.1
 GPR1
 G protein-coupled receptor 1
chr1_+_164528866 0.59 ENST00000420696.2
 PBX1
 pre-B-cell leukemia homeobox 1
chr1_+_156084461 0.58 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
 LMNA
 lamin A/C
chrX_+_102883887 0.58 ENST00000372625.3
ENST00000372624.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr18_-_57364588 0.57 ENST00000439986.4
 CCBE1
 collagen and calcium binding EGF domains 1
chr7_+_120629653 0.57 ENST00000450913.2
ENST00000340646.5
 CPED1
 cadherin-like and PC-esterase domain containing 1
chr2_+_172950227 0.56 ENST00000341900.6
 DLX1
 distal-less homeobox 1
chrX_-_106959631 0.56 ENST00000486554.1
ENST00000372390.4
 TSC22D3
 TSC22 domain family, member 3
chr4_-_2264015 0.55 ENST00000337190.2
 MXD4
 MAX dimerization protein 4
chr5_-_150473127 0.55 ENST00000521001.1
 TNIP1
 TNFAIP3 interacting protein 1
chr9_+_33795533 0.54 ENST00000379405.3
 PRSS3
 protease, serine, 3
chr1_-_102312517 0.54 ENST00000338858.5
 OLFM3
 olfactomedin 3
chr4_+_160188889 0.53 ENST00000264431.4
 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
chr5_-_137368708 0.53 ENST00000033079.3
 FAM13B
 family with sequence similarity 13, member B
chr12_+_79258444 0.53 ENST00000261205.4
 SYT1
 synaptotagmin I
chr12_+_56661033 0.52 ENST00000433805.2
 COQ10A
 coenzyme Q10 homolog A (S. cerevisiae)
chr2_-_65593784 0.52 ENST00000443619.2
 SPRED2
 sprouty-related, EVH1 domain containing 2
chr3_-_58563094 0.50 ENST00000464064.1
 FAM107A
 family with sequence similarity 107, member A
chr1_-_150780757 0.49 ENST00000271651.3
 CTSK
 cathepsin K
chr14_+_22615942 0.49 ENST00000390457.2
 TRAV27
 T cell receptor alpha variable 27
chr5_-_90679145 0.48 ENST00000265138.3
 ARRDC3
 arrestin domain containing 3
chr14_+_78870030 0.47 ENST00000553631.1
ENST00000554719.1
 NRXN3
 neurexin 3
chr7_-_7782204 0.47 ENST00000418534.2
 AC007161.5
 AC007161.5
chr6_-_152639479 0.46 ENST00000356820.4
 SYNE1
 spectrin repeat containing, nuclear envelope 1
chr20_-_45981138 0.46 ENST00000446994.2
 ZMYND8
 zinc finger, MYND-type containing 8
chr9_-_21482312 0.45 ENST00000448696.3
 IFNE
 interferon, epsilon
chr12_+_79258547 0.44 ENST00000457153.2
 SYT1
 synaptotagmin I
chr18_+_7754957 0.44 ENST00000400053.4
 PTPRM
 protein tyrosine phosphatase, receptor type, M
chrX_-_65259914 0.43 ENST00000374737.4
ENST00000455586.2
 VSIG4
 V-set and immunoglobulin domain containing 4
chr1_-_179834311 0.43 ENST00000553856.1
 IFRG15
 Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr17_-_64188177 0.43 ENST00000535342.2
 CEP112
 centrosomal protein 112kDa
chrX_+_54835493 0.43 ENST00000396224.1
 MAGED2
 melanoma antigen family D, 2
chr5_+_140734570 0.43 ENST00000571252.1
 PCDHGA4
 protocadherin gamma subfamily A, 4
chr15_+_43803143 0.43 ENST00000382031.1
 MAP1A
 microtubule-associated protein 1A
chr19_-_9546177 0.42 ENST00000592292.1
ENST00000588221.1
 ZNF266
 zinc finger protein 266
chr4_+_174089904 0.41 ENST00000265000.4
 GALNT7
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr2_-_224467093 0.41 ENST00000305409.2
 SCG2
 secretogranin II
chr5_+_140571902 0.41 ENST00000239446.4
 PCDHB10
 protocadherin beta 10
chr11_+_65266507 0.41 ENST00000544868.1
 MALAT1
 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr14_+_73525265 0.41 ENST00000525161.1
 RBM25
 RNA binding motif protein 25
chr1_-_204183071 0.40 ENST00000308302.3
 GOLT1A
 golgi transport 1A
chr1_-_17307173 0.40 ENST00000438542.1
ENST00000375535.3
 MFAP2
 microfibrillar-associated protein 2
chr19_-_9546227 0.39 ENST00000361451.2
ENST00000361151.1
 ZNF266
 zinc finger protein 266
chr19_-_31840438 0.39 ENST00000240587.4
 TSHZ3
 teashirt zinc finger homeobox 3
chr7_+_90338712 0.39 ENST00000265741.3
ENST00000406263.1
 CDK14
 cyclin-dependent kinase 14
chr17_-_76713100 0.38 ENST00000585509.1
 CYTH1
 cytohesin 1
chr19_-_51336443 0.38 ENST00000598673.1
 KLK15
 kallikrein-related peptidase 15
chr1_-_153599426 0.37 ENST00000392622.1
 S100A13
 S100 calcium binding protein A13
chr22_-_36013368 0.36 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
 MB
 myoglobin
chrX_-_39956656 0.36 ENST00000397354.3
ENST00000378444.4
 BCOR
 BCL6 corepressor
chr11_-_47600549 0.36 ENST00000430070.2
 KBTBD4
 kelch repeat and BTB (POZ) domain containing 4
chr11_-_47600320 0.36 ENST00000525720.1
ENST00000531067.1
ENST00000533290.1
ENST00000529499.1
ENST00000529946.1
ENST00000526005.1
ENST00000395288.2
ENST00000534239.1
 KBTBD4
 kelch repeat and BTB (POZ) domain containing 4
chr5_+_137774706 0.36 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
 REEP2
 receptor accessory protein 2
chr7_-_72739575 0.36 ENST00000453152.1
 TRIM50
 tripartite motif containing 50
chr15_+_65914260 0.36 ENST00000261892.6
ENST00000339868.6
 SLC24A1
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr19_-_37697976 0.36 ENST00000588873.1
 CTC-454I21.3
 Uncharacterized protein; Zinc finger protein 585B
chr4_+_170581213 0.35 ENST00000507875.1
 CLCN3
 chloride channel, voltage-sensitive 3
chrX_-_65259900 0.35 ENST00000412866.2
 VSIG4
 V-set and immunoglobulin domain containing 4
chr8_-_72987810 0.35 ENST00000262209.4
 TRPA1
 transient receptor potential cation channel, subfamily A, member 1
chr11_+_111807863 0.34 ENST00000440460.2
 DIXDC1
 DIX domain containing 1
chr16_+_222846 0.34 ENST00000251595.6
ENST00000397806.1
 HBA2
 hemoglobin, alpha 2
chr21_+_17792672 0.34 ENST00000602620.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr5_+_180682720 0.33 ENST00000599439.1
 AC008443.1
 CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr5_+_140710061 0.33 ENST00000517417.1
ENST00000378105.3
 PCDHGA1
 protocadherin gamma subfamily A, 1
chr12_+_49740700 0.33 ENST00000549441.2
ENST00000395069.3
 DNAJC22
 DnaJ (Hsp40) homolog, subfamily C, member 22
chr11_-_6426635 0.33 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
 APBB1
 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr1_+_164529004 0.32 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
 PBX1
 pre-B-cell leukemia homeobox 1
chr7_+_142457315 0.32 ENST00000486171.1
ENST00000311737.7
 PRSS1
 protease, serine, 1 (trypsin 1)
chr5_+_140718396 0.32 ENST00000394576.2
 PCDHGA2
 protocadherin gamma subfamily A, 2
chr21_-_35016231 0.31 ENST00000438788.1
 CRYZL1
 crystallin, zeta (quinone reductase)-like 1
chr20_+_43538692 0.31 ENST00000217074.4
ENST00000255136.3
 PABPC1L
 poly(A) binding protein, cytoplasmic 1-like
chr3_-_73673991 0.31 ENST00000308537.4
ENST00000263666.4
 PDZRN3
 PDZ domain containing ring finger 3
chr4_-_6711558 0.31 ENST00000320848.6
 MRFAP1L1
 Morf4 family associated protein 1-like 1
chr18_+_66465302 0.31 ENST00000360242.5
ENST00000358653.5
 CCDC102B
 coiled-coil domain containing 102B
chr15_+_54305101 0.31 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
 UNC13C
 unc-13 homolog C (C. elegans)
chr1_+_61547894 0.30 ENST00000403491.3
 NFIA
 nuclear factor I/A
chr2_-_20101385 0.30 ENST00000431392.1
 TTC32
 tetratricopeptide repeat domain 32
chr1_-_95391315 0.30 ENST00000545882.1
ENST00000415017.1
 CNN3
 calponin 3, acidic
chr3_-_185826855 0.30 ENST00000306376.5
 ETV5
 ets variant 5
chr21_+_27011584 0.30 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
 JAM2
 junctional adhesion molecule 2
chr1_+_153190053 0.30 ENST00000368744.3
 PRR9
 proline rich 9
chr1_+_10271674 0.29 ENST00000377086.1
 KIF1B
 kinesin family member 1B
chr3_-_46904946 0.29 ENST00000292327.4
 MYL3
 myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_-_144995074 0.29 ENST00000534536.1
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr3_-_46904918 0.29 ENST00000395869.1
 MYL3
 myosin, light chain 3, alkali; ventricular, skeletal, slow
chr4_+_114214125 0.29 ENST00000509550.1
 ANK2
 ankyrin 2, neuronal
chr4_+_189060573 0.29 ENST00000332517.3
 TRIML1
 tripartite motif family-like 1
chr13_-_45010939 0.29 ENST00000261489.2
 TSC22D1
 TSC22 domain family, member 1
chr11_-_82745238 0.28 ENST00000531021.1
 RAB30
 RAB30, member RAS oncogene family
chr3_-_186262166 0.28 ENST00000307944.5
 CRYGS
 crystallin, gamma S
chr6_+_74405501 0.28 ENST00000437994.2
ENST00000422508.2
 CD109
 CD109 molecule
chr5_+_59783540 0.28 ENST00000515734.2
 PART1
 prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_43291220 0.28 ENST00000372514.3
 ERMAP
 erythroblast membrane-associated protein (Scianna blood group)
chr5_+_76248538 0.28 ENST00000274368.4
 CRHBP
 corticotropin releasing hormone binding protein
chr7_+_90339169 0.28 ENST00000436577.2
 CDK14
 cyclin-dependent kinase 14
chr17_-_36413133 0.28 ENST00000523089.1
ENST00000312412.4
ENST00000520237.1
 RP11-1407O15.2
 TBC1 domain family member 3
chr20_-_56286479 0.28 ENST00000265626.4
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chr7_+_106809406 0.28 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
 HBP1
 HMG-box transcription factor 1
chr16_-_30905263 0.27 ENST00000572628.1
 BCL7C
 B-cell CLL/lymphoma 7C
chr13_+_76378407 0.27 ENST00000447038.1
 LMO7
 LIM domain 7
chr3_-_138312971 0.27 ENST00000485115.1
ENST00000484888.1
ENST00000468900.1
ENST00000542237.1
ENST00000481834.1
 CEP70
 centrosomal protein 70kDa
chr5_+_102455853 0.27 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
 PPIP5K2
 diphosphoinositol pentakisphosphate kinase 2
chr2_+_166095898 0.27 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
 SCN2A
 sodium channel, voltage-gated, type II, alpha subunit
chr14_+_31494672 0.27 ENST00000542754.2
ENST00000313566.6
 AP4S1
 adaptor-related protein complex 4, sigma 1 subunit
chr11_-_33913708 0.27 ENST00000257818.2
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr1_-_153599732 0.27 ENST00000392623.1
 S100A13
 S100 calcium binding protein A13
chr19_-_40596767 0.26 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
 ZNF780A
 zinc finger protein 780A
chr16_+_31404624 0.26 ENST00000389202.2
 ITGAD
 integrin, alpha D
chr14_+_31494841 0.26 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
 AP4S1
 adaptor-related protein complex 4, sigma 1 subunit
chrX_-_48858630 0.26 ENST00000376425.3
ENST00000376444.3
 GRIPAP1
 GRIP1 associated protein 1
chr16_+_66878282 0.26 ENST00000338437.2
 CA7
 carbonic anhydrase VII
chr11_+_30252549 0.26 ENST00000254122.3
ENST00000417547.1
 FSHB
 follicle stimulating hormone, beta polypeptide
chr2_-_216257849 0.26 ENST00000456923.1
 FN1
 fibronectin 1
chr5_+_161275320 0.25 ENST00000437025.2
 GABRA1
 gamma-aminobutyric acid (GABA) A receptor, alpha 1
chrX_-_48858667 0.25 ENST00000376423.4
ENST00000376441.1
 GRIPAP1
 GRIP1 associated protein 1
chr13_-_103053946 0.25 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr1_+_32645645 0.25 ENST00000373609.1
 TXLNA
 taxilin alpha
chr8_+_36641842 0.25 ENST00000523973.1
ENST00000399881.3
 KCNU1
 potassium channel, subfamily U, member 1
chrX_+_36065053 0.25 ENST00000313548.4
 CHDC2
 calponin homology domain containing 2
chr1_+_43282782 0.24 ENST00000372517.2
 ERMAP
 erythroblast membrane-associated protein (Scianna blood group)
chr19_+_47421933 0.24 ENST00000404338.3
 ARHGAP35
 Rho GTPase activating protein 35
chr5_+_59783941 0.24 ENST00000506884.1
ENST00000504876.2
 PART1
 prostate androgen-regulated transcript 1 (non-protein coding)
chr11_+_66406149 0.24 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
 RBM4
 RNA binding motif protein 4
chr6_+_69942298 0.24 ENST00000238918.8
 BAI3
 brain-specific angiogenesis inhibitor 3
chr15_+_76629064 0.24 ENST00000290759.4
 ISL2
 ISL LIM homeobox 2
chr12_+_103981044 0.23 ENST00000388887.2
 STAB2
 stabilin 2
chrX_-_107682702 0.23 ENST00000372216.4
 COL4A6
 collagen, type IV, alpha 6
chr15_+_65914347 0.23 ENST00000544319.2
 SLC24A1
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr2_+_106682103 0.23 ENST00000238044.3
 C2orf40
 chromosome 2 open reading frame 40
chr5_+_102201430 0.23 ENST00000438793.3
ENST00000346918.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr5_+_102201687 0.23 ENST00000304400.7
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr16_+_29819372 0.23 ENST00000568544.1
ENST00000569978.1
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr8_+_77318769 0.23 ENST00000518732.1
 RP11-706J10.1
 long intergenic non-protein coding RNA 1111
chr11_+_65479702 0.22 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
 KAT5
 K(lysine) acetyltransferase 5
chr17_-_40575535 0.22 ENST00000357037.5
 PTRF
 polymerase I and transcript release factor
chr5_+_161274685 0.22 ENST00000428797.2
 GABRA1
 gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_152943122 0.22 ENST00000328051.2
 SPRR4
 small proline-rich protein 4
chr6_-_131291572 0.22 ENST00000529208.1
 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
chr1_-_43282906 0.22 ENST00000372521.4
 CCDC23
 coiled-coil domain containing 23
chr1_-_47131521 0.22 ENST00000542495.1
ENST00000532925.1
 ATPAF1
 ATP synthase mitochondrial F1 complex assembly factor 1
chr5_+_102201509 0.22 ENST00000348126.2
ENST00000379787.4
 PAM
 peptidylglycine alpha-amidating monooxygenase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.6 1.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.4 1.5 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.4 3.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 0.9 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 0.9 GO:0018032 protein amidation(GO:0018032)
0.2 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.6 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 1.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.5 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.5 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.8 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.2 1.5 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.1 1.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 2.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.6 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 1.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.6 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.5 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1 0.5 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.3 GO:1904647 response to rotenone(GO:1904647)
0.1 3.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.4 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.5 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.6 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0050968 thermoception(GO:0050955) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.2 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.3 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 1.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.0 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 1.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.3 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.2 GO:0042113 B cell activation(GO:0042113)
0.0 0.2 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.8 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.6 GO:0009642 response to light intensity(GO:0009642)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 1.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.3 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.1 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.1 GO:0071383 steroid hormone mediated signaling pathway(GO:0043401) cellular response to steroid hormone stimulus(GO:0071383)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.8 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 4.6 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 2.6 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0044305 calyx of Held(GO:0044305)
0.2 1.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 2.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 4.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 2.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 4.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.1 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0050436 microfibril binding(GO:0050436)
0.2 3.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 0.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 1.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 2.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 1.2 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 5.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 3.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 1.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 4.7 GO:0005518 collagen binding(GO:0005518)
0.0 1.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 2.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.0 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 5.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics