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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for OLIG3_NEUROD2_NEUROG2

Z-value: 0.99

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Transcription factors associated with OLIG3_NEUROD2_NEUROG2

Gene Symbol Gene ID Gene Info
ENSG00000177468.5 OLIG3
ENSG00000171532.4 NEUROD2
ENSG00000178403.3 NEUROG2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NEUROG2hg19_v2_chr4_-_113437328_1134373370.714.9e-02Click!
NEUROD2hg19_v2_chr17_-_37764128_37764258-0.667.5e-02Click!
OLIG3hg19_v2_chr6_-_137815524_137815537-0.472.4e-01Click!

Activity profile of OLIG3_NEUROD2_NEUROG2 motif

Sorted Z-values of OLIG3_NEUROD2_NEUROG2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG3_NEUROD2_NEUROG2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_91573132 3.61 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr5_-_111312622 3.46 ENST00000395634.3
NREP
neuronal regeneration related protein
chr12_-_91573316 2.64 ENST00000393155.1
DCN
decorin
chr12_-_91546926 2.29 ENST00000550758.1
DCN
decorin
chr2_-_188378368 2.28 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_189839046 1.74 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr3_-_195310802 1.66 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr5_-_75919253 1.36 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr2_-_158345462 1.19 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr8_-_93029865 1.17 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_108714412 0.97 ENST00000412676.1
ENST00000550573.1
CMKLR1
chemokine-like receptor 1
chr9_+_18474098 0.93 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr1_-_186344802 0.90 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr12_-_91573249 0.86 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr16_+_53133070 0.83 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr20_+_34802295 0.83 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr15_-_63448973 0.76 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr15_-_98417780 0.73 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr7_-_97881429 0.73 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr13_+_49551020 0.72 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr5_-_75919217 0.70 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr2_+_210444748 0.70 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr6_+_73076432 0.69 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr9_-_95244781 0.68 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr16_+_21716284 0.68 ENST00000388957.3
OTOA
otoancorin
chr4_+_160188889 0.67 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr3_+_69928256 0.67 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr14_-_75079026 0.65 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr6_-_31648150 0.61 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr2_-_163099885 0.61 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr1_+_104293028 0.60 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr2_+_33359646 0.59 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_33359687 0.58 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr2_-_175462934 0.58 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr4_-_89619386 0.56 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr11_+_113930291 0.56 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr2_-_163100045 0.55 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr3_-_114477962 0.55 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_182545603 0.55 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr3_-_114477787 0.54 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_46459675 0.54 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chr2_+_108994466 0.52 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr9_+_90112117 0.52 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr14_-_53417732 0.50 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr17_-_53809473 0.49 ENST00000575734.1
TMEM100
transmembrane protein 100
chr3_-_18480260 0.48 ENST00000454909.2
SATB1
SATB homeobox 1
chr15_-_55700216 0.45 ENST00000569205.1
CCPG1
cell cycle progression 1
chr2_+_108994633 0.45 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chrX_+_70798261 0.43 ENST00000373696.3
ACRC
acidic repeat containing
chr4_+_114214125 0.42 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr1_+_89990431 0.42 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr1_+_95975672 0.42 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr7_+_90893783 0.41 ENST00000287934.2
FZD1
frizzled family receptor 1
chr3_-_178984759 0.41 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr5_-_137674000 0.40 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr6_+_3000195 0.39 ENST00000338130.2
NQO2
NAD(P)H dehydrogenase, quinone 2
chr22_+_44319619 0.38 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr11_-_63376013 0.38 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr3_+_141043050 0.37 ENST00000509842.1
ZBTB38
zinc finger and BTB domain containing 38
chr6_+_3000218 0.37 ENST00000380441.1
ENST00000380455.4
ENST00000380454.4
NQO2
NAD(P)H dehydrogenase, quinone 2
chr6_+_3000057 0.35 ENST00000397717.2
NQO2
NAD(P)H dehydrogenase, quinone 2
chr5_-_171433579 0.35 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr10_+_85954377 0.35 ENST00000332904.3
ENST00000372117.3
CDHR1
cadherin-related family member 1
chr15_+_62853562 0.34 ENST00000561311.1
TLN2
talin 2
chr1_-_144994909 0.34 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr5_+_140571902 0.34 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr4_-_159094194 0.34 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr16_-_66583701 0.34 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2
thymidine kinase 2, mitochondrial
chr18_-_10748498 0.33 ENST00000579949.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr11_-_134123142 0.33 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chrX_-_19140677 0.33 ENST00000357544.3
ENST00000379869.3
ENST00000360279.4
ENST00000379873.2
ENST00000379878.3
ENST00000354791.3
ENST00000379876.1
GPR64
G protein-coupled receptor 64
chr5_+_135496675 0.33 ENST00000507637.1
SMAD5
SMAD family member 5
chr12_+_26126681 0.33 ENST00000542865.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr3_+_185300391 0.33 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr1_-_232598163 0.32 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr10_-_31288398 0.32 ENST00000538351.2
ZNF438
zinc finger protein 438
chr12_+_55248289 0.32 ENST00000308796.6
MUCL1
mucin-like 1
chr10_-_49812997 0.31 ENST00000417912.2
ARHGAP22
Rho GTPase activating protein 22
chr7_+_134430212 0.31 ENST00000436461.2
CALD1
caldesmon 1
chr6_-_52859046 0.31 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr17_-_28618867 0.31 ENST00000394819.3
ENST00000577623.1
BLMH
bleomycin hydrolase
chr11_+_134123389 0.30 ENST00000281182.4
ENST00000537423.1
ENST00000543332.1
ENST00000374752.4
ACAD8
acyl-CoA dehydrogenase family, member 8
chr4_-_171011084 0.30 ENST00000337664.4
AADAT
aminoadipate aminotransferase
chr19_-_37019562 0.29 ENST00000523638.1
ZNF260
zinc finger protein 260
chr3_+_148457585 0.29 ENST00000402260.1
AGTR1
angiotensin II receptor, type 1
chr19_+_18208603 0.29 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr17_+_66511540 0.29 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_-_150736962 0.28 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
RP11-526A4.1
chr15_-_55700522 0.28 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr19_+_14551066 0.28 ENST00000342216.4
PKN1
protein kinase N1
chrX_-_13835147 0.28 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr5_-_171433819 0.28 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr17_-_8770956 0.28 ENST00000311434.9
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr16_-_4896205 0.27 ENST00000589389.1
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr9_-_123239632 0.27 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr13_-_114312501 0.26 ENST00000335288.4
ATP4B
ATPase, H+/K+ exchanging, beta polypeptide
chr15_+_74466012 0.26 ENST00000249842.3
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr8_-_23315190 0.25 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr9_+_18474163 0.25 ENST00000380566.4
ADAMTSL1
ADAMTS-like 1
chr21_+_37507210 0.24 ENST00000290354.5
CBR3
carbonyl reductase 3
chrX_-_13835461 0.24 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr14_-_106539557 0.24 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr13_+_28519343 0.24 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr10_-_49813090 0.24 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr11_+_75428857 0.24 ENST00000198801.5
MOGAT2
monoacylglycerol O-acyltransferase 2
chr1_-_111970353 0.23 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa
chrX_+_69509927 0.23 ENST00000374403.3
KIF4A
kinesin family member 4A
chr2_-_79313973 0.23 ENST00000454188.1
REG1B
regenerating islet-derived 1 beta
chr2_-_152830441 0.23 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr20_-_34117447 0.23 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173
chromosome 20 open reading frame 173
chr4_+_71457970 0.22 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr5_+_157158205 0.22 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr1_-_144995074 0.22 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_145076186 0.21 ENST00000369348.3
PDE4DIP
phosphodiesterase 4D interacting protein
chrX_+_47444613 0.21 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr9_-_130635741 0.21 ENST00000223836.10
AK1
adenylate kinase 1
chr1_+_145883868 0.21 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr2_-_154335300 0.21 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr2_+_54342574 0.21 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chr1_+_12524965 0.20 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chrX_+_152082969 0.20 ENST00000535861.1
ENST00000539731.1
ENST00000449285.2
ENST00000318504.7
ENST00000324823.6
ENST00000370268.4
ENST00000370270.2
ZNF185
zinc finger protein 185 (LIM domain)
chr7_+_148287657 0.20 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr15_-_90358048 0.20 ENST00000300060.6
ENST00000560137.1
ANPEP
alanyl (membrane) aminopeptidase
chr12_+_133657461 0.20 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140
zinc finger protein 140
chr14_+_22217447 0.20 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr12_-_11002063 0.20 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr10_-_38265517 0.19 ENST00000302609.7
ZNF25
zinc finger protein 25
chr9_+_2029019 0.19 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_12035878 0.19 ENST00000254321.5
ENST00000538752.1
ENST00000590798.1
ZNF700
ZNF763
ZNF763
zinc finger protein 700
zinc finger protein 763
Uncharacterized protein; Zinc finger protein 763
chr5_+_140753444 0.19 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr4_+_74718906 0.19 ENST00000226524.3
PF4V1
platelet factor 4 variant 1
chr12_+_117348742 0.19 ENST00000309909.5
ENST00000455858.2
FBXW8
F-box and WD repeat domain containing 8
chr6_-_74363803 0.19 ENST00000355773.5
SLC17A5
solute carrier family 17 (acidic sugar transporter), member 5
chr1_+_144215387 0.19 ENST00000421555.2
NBPF8
neuroblastoma breakpoint family, member 8
chr17_-_7145475 0.19 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr5_+_148737562 0.19 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr15_-_50557863 0.19 ENST00000543581.1
HDC
histidine decarboxylase
chr14_-_23904861 0.19 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr21_-_43786634 0.19 ENST00000291527.2
TFF1
trefoil factor 1
chr2_+_136499179 0.19 ENST00000272638.9
UBXN4
UBX domain protein 4
chr17_-_15168624 0.19 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr19_-_21512202 0.18 ENST00000356929.3
ZNF708
zinc finger protein 708
chr20_-_32031680 0.18 ENST00000217381.2
SNTA1
syntrophin, alpha 1
chr16_+_28889703 0.18 ENST00000357084.3
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr18_+_32455201 0.18 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr7_-_38403077 0.18 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr6_+_151561085 0.18 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr10_-_28571015 0.18 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr9_-_73029540 0.18 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr17_+_60758814 0.17 ENST00000579432.1
ENST00000446119.2
MRC2
mannose receptor, C type 2
chr9_-_127703333 0.17 ENST00000373555.4
GOLGA1
golgin A1
chr1_+_225600404 0.17 ENST00000366845.2
AC092811.1
AC092811.1
chr20_-_45061695 0.17 ENST00000445496.2
ELMO2
engulfment and cell motility 2
chr19_+_8478154 0.17 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr9_-_104357277 0.17 ENST00000374806.1
PPP3R2
protein phosphatase 3, regulatory subunit B, beta
chr11_-_66104237 0.17 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr10_+_92980517 0.16 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr19_-_39368887 0.16 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr11_-_110167352 0.16 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr14_-_94984181 0.16 ENST00000341228.2
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr1_-_241799232 0.16 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr19_+_44764031 0.16 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
ZNF233
zinc finger protein 233
chr19_+_12273866 0.16 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136
zinc finger protein 136
chr2_+_223162866 0.16 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr3_-_105588231 0.16 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr2_+_201994042 0.15 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_+_112810878 0.15 ENST00000434623.2
ENST00000374525.1
AKAP2
A kinase (PRKA) anchor protein 2
chr3_+_48507621 0.15 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr12_+_52643077 0.15 ENST00000553310.2
ENST00000544024.1
KRT86
keratin 86
chr16_+_28889801 0.15 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_-_26743546 0.15 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr17_+_77681075 0.15 ENST00000397549.2
CTD-2116F7.1
CTD-2116F7.1
chr20_-_35274548 0.15 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr18_-_56296182 0.15 ENST00000361673.3
ALPK2
alpha-kinase 2
chr21_+_17566643 0.15 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr12_+_56862301 0.15 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chr17_-_58469687 0.15 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr12_+_10124001 0.15 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr1_-_146054494 0.15 ENST00000401009.2
NBPF11
neuroblastoma breakpoint family, member 11
chr5_-_114632307 0.14 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr10_+_180405 0.14 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr1_+_22351977 0.14 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr3_-_53916202 0.14 ENST00000335754.3
ACTR8
ARP8 actin-related protein 8 homolog (yeast)
chr6_+_29427548 0.14 ENST00000377132.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr4_-_74088800 0.14 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr11_+_120107344 0.14 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr2_+_178257372 0.13 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chrX_+_120181457 0.13 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr6_-_33714667 0.13 ENST00000293756.4
IP6K3
inositol hexakisphosphate kinase 3
chr11_-_88796803 0.13 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr1_-_95392635 0.13 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr16_+_53088885 0.13 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr12_+_54393880 0.13 ENST00000303450.4
HOXC9
homeobox C9
chr2_+_74781828 0.13 ENST00000340004.6
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chrX_+_118108601 0.13 ENST00000371628.3
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr17_-_19281203 0.13 ENST00000487415.2
B9D1
B9 protein domain 1
chr14_+_95047725 0.13 ENST00000554760.1
ENST00000554866.1
ENST00000329597.7
ENST00000556775.1
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr21_+_31768348 0.13 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr14_+_95047744 0.13 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr19_-_10445399 0.13 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.6 9.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6 1.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.9 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.3 2.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.5 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.2 0.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 2.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.3 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.3 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 1.0 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 1.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 1.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 1.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.0 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.0 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.1 0.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0044297 cell body(GO:0044297)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.6 GO:0043234 protein complex(GO:0043234)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 1.5 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.1 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.2 1.1 GO:0050436 microfibril binding(GO:0050436)
0.1 0.7 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 9.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.3 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.3 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 1.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.8 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 2.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism