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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for OTX2_CRX

Z-value: 0.67

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 OTX2
CRX
ENSG00000105392.11 CRX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX2hg19_v2_chr14_-_57277163_57277168-0.772.5e-02Click!
CRXhg19_v2_chr19_+_48325097_48325211-0.294.8e-01Click!

Activity profile of OTX2_CRX motif

Sorted Z-values of OTX2_CRX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_+_70378852 0.52 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
 SULF1
 sulfatase 1
chr12_+_6949964 0.49 ENST00000541978.1
ENST00000435982.2
 GNB3
 guanine nucleotide binding protein (G protein), beta polypeptide 3
chr5_-_41510725 0.42 ENST00000328457.3
 PLCXD3
 phosphatidylinositol-specific phospholipase C, X domain containing 3
chr5_-_41510656 0.42 ENST00000377801.3
 PLCXD3
 phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_-_2027639 0.32 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
 CACNA2D4
 calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr1_+_114522049 0.29 ENST00000369551.1
ENST00000320334.4
 OLFML3
 olfactomedin-like 3
chr12_-_91576561 0.29 ENST00000547568.2
ENST00000552962.1
 DCN
 decorin
chr12_-_91576429 0.29 ENST00000552145.1
ENST00000546745.1
 DCN
 decorin
chr12_-_91576750 0.28 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
 DCN
 decorin
chr1_+_159141397 0.25 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3
 cell adhesion molecule 3
chrX_+_69488174 0.25 ENST00000480877.2
ENST00000307959.8
 ARR3
 arrestin 3, retinal (X-arrestin)
chr9_-_95244781 0.24 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
 ASPN
 asporin
chr2_+_128175997 0.23 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
 PROC
 protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_120770581 0.23 ENST00000263713.5
 EPB41L5
 erythrocyte membrane protein band 4.1 like 5
chr2_-_175711133 0.23 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chr1_-_165414414 0.22 ENST00000359842.5
 RXRG
 retinoid X receptor, gamma
chrX_-_101771645 0.21 ENST00000289373.4
 TMSB15A
 thymosin beta 15a
chr18_-_70532906 0.20 ENST00000299430.2
ENST00000397929.1
 NETO1
 neuropilin (NRP) and tolloid (TLL)-like 1
chr12_+_7941989 0.20 ENST00000229307.4
 NANOG
 Nanog homeobox
chr7_-_128415844 0.19 ENST00000249389.2
 OPN1SW
 opsin 1 (cone pigments), short-wave-sensitive
chr6_-_42690312 0.19 ENST00000230381.5
 PRPH2
 peripherin 2 (retinal degeneration, slow)
chr5_+_145718587 0.19 ENST00000230732.4
 POU4F3
 POU class 4 homeobox 3
chr5_-_88178964 0.18 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
 MEF2C
 myocyte enhancer factor 2C
chr5_-_88179017 0.18 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
 MEF2C
 myocyte enhancer factor 2C
chr19_+_2476116 0.16 ENST00000215631.4
ENST00000587345.1
 GADD45B
 growth arrest and DNA-damage-inducible, beta
chr2_+_120770645 0.16 ENST00000443902.2
 EPB41L5
 erythrocyte membrane protein band 4.1 like 5
chr2_-_175499294 0.16 ENST00000392547.2
 WIPF1
 WAS/WASL interacting protein family, member 1
chr11_-_8680383 0.16 ENST00000299550.6
 TRIM66
 tripartite motif containing 66
chr5_-_149324306 0.15 ENST00000255266.5
 PDE6A
 phosphodiesterase 6A, cGMP-specific, rod, alpha
chr17_-_46690839 0.15 ENST00000498634.2
 HOXB8
 homeobox B8
chr11_-_111794446 0.15 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr3_+_141105705 0.15 ENST00000513258.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr19_-_51538148 0.14 ENST00000319590.4
ENST00000250351.4
 KLK12
 kallikrein-related peptidase 12
chr19_-_51538118 0.14 ENST00000529888.1
 KLK12
 kallikrein-related peptidase 12
chr11_-_111783595 0.14 ENST00000528628.1
 CRYAB
 crystallin, alpha B
chr1_+_159409512 0.14 ENST00000423932.3
 OR10J1
 olfactory receptor, family 10, subfamily J, member 1
chr3_-_54962100 0.13 ENST00000273286.5
 LRTM1
 leucine-rich repeats and transmembrane domains 1
chr17_-_9808887 0.13 ENST00000226193.5
 RCVRN
 recoverin
chr8_-_25281747 0.13 ENST00000421054.2
 GNRH1
 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr16_-_31076332 0.12 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
 ZNF668
 zinc finger protein 668
chrX_+_69488155 0.12 ENST00000374495.3
 ARR3
 arrestin 3, retinal (X-arrestin)
chr16_+_58010339 0.12 ENST00000290871.5
ENST00000441824.2
 TEPP
 testis, prostate and placenta expressed
chr1_+_144989309 0.12 ENST00000596396.1
 AL590452.1
 Uncharacterized protein
chr6_-_31697563 0.11 ENST00000375789.2
ENST00000416410.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr14_-_101034407 0.11 ENST00000443071.2
ENST00000557378.1
 BEGAIN
 brain-enriched guanylate kinase-associated
chr9_-_20622478 0.11 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr3_+_69915385 0.11 ENST00000314589.5
 MITF
 microphthalmia-associated transcription factor
chr13_-_33780133 0.11 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr9_+_18474098 0.11 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
 ADAMTSL1
 ADAMTS-like 1
chr1_+_164528866 0.11 ENST00000420696.2
 PBX1
 pre-B-cell leukemia homeobox 1
chr16_-_31076273 0.11 ENST00000426488.2
 ZNF668
 zinc finger protein 668
chr1_+_18957500 0.10 ENST00000375375.3
 PAX7
 paired box 7
chr2_-_119605253 0.10 ENST00000295206.6
 EN1
 engrailed homeobox 1
chr1_-_241799232 0.10 ENST00000366553.1
 CHML
 choroideremia-like (Rab escort protein 2)
chr6_-_31697255 0.10 ENST00000436437.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr7_-_97881429 0.09 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
 TECPR1
 tectonin beta-propeller repeat containing 1
chr10_+_95848824 0.09 ENST00000371385.3
ENST00000371375.1
 PLCE1
 phospholipase C, epsilon 1
chr3_-_179692042 0.09 ENST00000468741.1
 PEX5L
 peroxisomal biogenesis factor 5-like
chr17_-_48207157 0.09 ENST00000330175.4
ENST00000503131.1
 SAMD14
 sterile alpha motif domain containing 14
chr1_+_11751748 0.09 ENST00000294485.5
 DRAXIN
 dorsal inhibitory axon guidance protein
chr3_-_190580404 0.09 ENST00000442080.1
 GMNC
 geminin coiled-coil domain containing
chr9_-_13279563 0.09 ENST00000541718.1
 MPDZ
 multiple PDZ domain protein
chr5_+_5140436 0.08 ENST00000511368.1
ENST00000274181.7
 ADAMTS16
 ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr7_+_90338712 0.08 ENST00000265741.3
ENST00000406263.1
 CDK14
 cyclin-dependent kinase 14
chrX_+_79675965 0.08 ENST00000308293.5
 FAM46D
 family with sequence similarity 46, member D
chr1_+_207277590 0.08 ENST00000367070.3
 C4BPA
 complement component 4 binding protein, alpha
chr15_+_33603147 0.08 ENST00000415757.3
ENST00000389232.4
 RYR3
 ryanodine receptor 3
chr3_+_63953415 0.08 ENST00000484332.1
 ATXN7
 ataxin 7
chr5_-_149669192 0.08 ENST00000398376.3
 CAMK2A
 calcium/calmodulin-dependent protein kinase II alpha
chr17_-_4689649 0.08 ENST00000441199.2
ENST00000416307.2
 VMO1
 vitelline membrane outer layer 1 homolog (chicken)
chr10_-_62761188 0.08 ENST00000357917.4
 RHOBTB1
 Rho-related BTB domain containing 1
chr14_-_67981870 0.07 ENST00000555994.1
 TMEM229B
 transmembrane protein 229B
chr1_+_164529004 0.07 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
 PBX1
 pre-B-cell leukemia homeobox 1
chr6_-_111804905 0.07 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr7_-_128171123 0.07 ENST00000608477.1
 RP11-212P7.2
 RP11-212P7.2
chr12_-_13248705 0.07 ENST00000396310.2
 GSG1
 germ cell associated 1
chr10_+_103986085 0.07 ENST00000370005.3
 ELOVL3
 ELOVL fatty acid elongase 3
chrX_+_15767971 0.07 ENST00000479740.1
ENST00000454127.2
 CA5B
 carbonic anhydrase VB, mitochondrial
chr9_-_13279589 0.07 ENST00000319217.7
 MPDZ
 multiple PDZ domain protein
chr14_-_22005018 0.07 ENST00000546363.1
 SALL2
 spalt-like transcription factor 2
chr10_+_24528108 0.07 ENST00000438429.1
 KIAA1217
 KIAA1217
chr12_-_13248732 0.07 ENST00000396302.3
 GSG1
 germ cell associated 1
chr10_-_104178857 0.07 ENST00000020673.5
 PSD
 pleckstrin and Sec7 domain containing
chr11_+_61522844 0.06 ENST00000265460.5
 MYRF
 myelin regulatory factor
chr6_+_155537771 0.06 ENST00000275246.7
 TIAM2
 T-cell lymphoma invasion and metastasis 2
chr12_-_13248562 0.06 ENST00000457134.2
ENST00000537302.1
 GSG1
 germ cell associated 1
chr7_-_100171270 0.06 ENST00000538735.1
 SAP25
 Sin3A-associated protein, 25kDa
chr19_-_44124019 0.06 ENST00000300811.3
 ZNF428
 zinc finger protein 428
chr4_+_70894130 0.06 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
 HTN3
 histatin 3
chr12_+_133757995 0.06 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
 ZNF268
 zinc finger protein 268
chr5_-_95768973 0.06 ENST00000311106.3
 PCSK1
 proprotein convertase subtilisin/kexin type 1
chr11_+_20044096 0.06 ENST00000533917.1
 NAV2
 neuron navigator 2
chr1_+_169079823 0.06 ENST00000367813.3
 ATP1B1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
chr20_-_31124186 0.06 ENST00000375678.3
 C20orf112
 chromosome 20 open reading frame 112
chr3_+_129247479 0.06 ENST00000296271.3
 RHO
 rhodopsin
chr2_+_201170703 0.06 ENST00000358677.5
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr19_+_11457175 0.06 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
 CCDC159
 coiled-coil domain containing 159
chr12_-_90049828 0.06 ENST00000261173.2
ENST00000348959.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr2_+_219472488 0.05 ENST00000450993.2
 PLCD4
 phospholipase C, delta 4
chr9_+_75229616 0.05 ENST00000340019.3
 TMC1
 transmembrane channel-like 1
chr19_-_59066452 0.05 ENST00000312547.2
 CHMP2A
 charged multivesicular body protein 2A
chr5_-_150138061 0.05 ENST00000521533.1
ENST00000424236.1
 DCTN4
 dynactin 4 (p62)
chr12_-_90049878 0.05 ENST00000359142.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr9_+_18474204 0.05 ENST00000276935.6
 ADAMTSL1
 ADAMTS-like 1
chr11_-_128712362 0.05 ENST00000392664.2
 KCNJ1
 potassium inwardly-rectifying channel, subfamily J, member 1
chr19_-_10121144 0.05 ENST00000264828.3
 COL5A3
 collagen, type V, alpha 3
chr12_+_40787194 0.05 ENST00000425730.2
ENST00000454784.4
 MUC19
 mucin 19, oligomeric
chr10_-_49482907 0.05 ENST00000374201.3
ENST00000407470.4
 FRMPD2
 FERM and PDZ domain containing 2
chr14_+_88471468 0.05 ENST00000267549.3
 GPR65
 G protein-coupled receptor 65
chr3_-_50605077 0.05 ENST00000426034.1
ENST00000441239.1
 C3orf18
 chromosome 3 open reading frame 18
chr5_+_133451254 0.05 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
chr13_-_49975632 0.05 ENST00000457041.1
ENST00000355854.4
 CAB39L
 calcium binding protein 39-like
chr10_+_18240834 0.05 ENST00000377371.3
ENST00000539911.1
 SLC39A12
 solute carrier family 39 (zinc transporter), member 12
chr17_-_14683517 0.05 ENST00000379640.1
 AC005863.1
 AC005863.1
chr12_-_53171128 0.05 ENST00000332411.2
 KRT76
 keratin 76
chr3_-_149095652 0.05 ENST00000305366.3
 TM4SF1
 transmembrane 4 L six family member 1
chr15_-_31453359 0.05 ENST00000542188.1
 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
chr4_+_129730947 0.05 ENST00000452328.2
ENST00000504089.1
 PHF17
 jade family PHD finger 1
chr6_-_9933500 0.05 ENST00000492169.1
 OFCC1
 orofacial cleft 1 candidate 1
chr1_-_117664317 0.05 ENST00000256649.4
ENST00000369464.3
ENST00000485032.1
 TRIM45
 tripartite motif containing 45
chr4_+_154125565 0.05 ENST00000338700.5
 TRIM2
 tripartite motif containing 2
chr11_+_72975559 0.05 ENST00000349767.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_-_50605150 0.04 ENST00000357203.3
 C3orf18
 chromosome 3 open reading frame 18
chr5_+_173316341 0.04 ENST00000520867.1
ENST00000334035.5
 CPEB4
 cytoplasmic polyadenylation element binding protein 4
chr14_+_23846328 0.04 ENST00000382809.2
 CMTM5
 CKLF-like MARVEL transmembrane domain containing 5
chr22_-_38380543 0.04 ENST00000396884.2
 SOX10
 SRY (sex determining region Y)-box 10
chr1_+_20396649 0.04 ENST00000375108.3
 PLA2G5
 phospholipase A2, group V
chr20_+_4702548 0.04 ENST00000305817.2
 PRND
 prion protein 2 (dublet)
chr2_-_121223697 0.04 ENST00000593290.1
 FLJ14816
 long intergenic non-protein coding RNA 1101
chr11_+_72975524 0.04 ENST00000540342.1
ENST00000542092.1
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr15_+_58430368 0.04 ENST00000558772.1
ENST00000219919.4
 AQP9
 aquaporin 9
chr11_+_72975578 0.04 ENST00000393592.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr9_+_82188077 0.04 ENST00000425506.1
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_146082633 0.04 ENST00000605317.1
ENST00000604938.1
ENST00000339388.5
 NBPF11
 neuroblastoma breakpoint family, member 11
chr19_-_44123734 0.04 ENST00000598676.1
 ZNF428
 zinc finger protein 428
chr9_+_17134980 0.04 ENST00000380647.3
 CNTLN
 centlein, centrosomal protein
chr11_-_67290867 0.04 ENST00000353903.5
ENST00000294288.4
 CABP2
 calcium binding protein 2
chr8_-_10512569 0.04 ENST00000382483.3
 RP1L1
 retinitis pigmentosa 1-like 1
chr3_-_186262166 0.04 ENST00000307944.5
 CRYGS
 crystallin, gamma S
chr19_+_46001697 0.04 ENST00000451287.2
ENST00000324688.4
 PPM1N
 protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr10_+_18240753 0.04 ENST00000377369.2
 SLC39A12
 solute carrier family 39 (zinc transporter), member 12
chr11_+_67222818 0.04 ENST00000325656.5
 CABP4
 calcium binding protein 4
chr3_+_191046810 0.04 ENST00000392455.3
ENST00000392456.3
 CCDC50
 coiled-coil domain containing 50
chr10_+_18240814 0.04 ENST00000377374.4
 SLC39A12
 solute carrier family 39 (zinc transporter), member 12
chr7_+_28452130 0.04 ENST00000357727.2
 CREB5
 cAMP responsive element binding protein 5
chr4_+_129730779 0.04 ENST00000226319.6
 PHF17
 jade family PHD finger 1
chr1_+_151682909 0.04 ENST00000326413.3
ENST00000442233.2
 RIIAD1
AL589765.1
 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr10_+_134150835 0.04 ENST00000432555.2
 LRRC27
 leucine rich repeat containing 27
chr1_-_173174681 0.04 ENST00000367718.1
 TNFSF4
 tumor necrosis factor (ligand) superfamily, member 4
chr2_+_170366203 0.04 ENST00000284669.1
 KLHL41
 kelch-like family member 41
chr11_-_30608413 0.04 ENST00000528686.1
 MPPED2
 metallophosphoesterase domain containing 2
chr12_-_7848364 0.04 ENST00000329913.3
 GDF3
 growth differentiation factor 3
chr5_+_161494521 0.04 ENST00000356592.3
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr6_+_54173227 0.04 ENST00000259782.4
ENST00000370864.3
 TINAG
 tubulointerstitial nephritis antigen
chr18_+_29769978 0.03 ENST00000269202.6
ENST00000581447.1
 MEP1B
 meprin A, beta
chr10_-_65028817 0.03 ENST00000542921.1
 JMJD1C
 jumonji domain containing 1C
chr6_+_111580508 0.03 ENST00000368847.4
 KIAA1919
 KIAA1919
chr15_+_58430567 0.03 ENST00000536493.1
 AQP9
 aquaporin 9
chr3_-_137851220 0.03 ENST00000236709.3
 A4GNT
 alpha-1,4-N-acetylglucosaminyltransferase
chr8_-_114449112 0.03 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
 CSMD3
 CUB and Sushi multiple domains 3
chr15_-_74495188 0.03 ENST00000563965.1
ENST00000395105.4
 STRA6
 stimulated by retinoic acid 6
chr10_-_65028938 0.03 ENST00000402544.1
 JMJD1C
 jumonji domain containing 1C
chr9_+_34179003 0.03 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
 UBAP1
 ubiquitin associated protein 1
chrX_+_153409678 0.03 ENST00000369951.4
 OPN1LW
 opsin 1 (cone pigments), long-wave-sensitive
chr15_+_54901540 0.03 ENST00000539562.2
 UNC13C
 unc-13 homolog C (C. elegans)
chr1_-_53608249 0.03 ENST00000371494.4
 SLC1A7
 solute carrier family 1 (glutamate transporter), member 7
chr1_-_102312517 0.03 ENST00000338858.5
 OLFM3
 olfactomedin 3
chr17_-_39661849 0.03 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
 KRT13
 keratin 13
chr3_-_9291063 0.03 ENST00000383836.3
 SRGAP3
 SLIT-ROBO Rho GTPase activating protein 3
chrM_+_9207 0.03 ENST00000362079.2
 MT-CO3
 mitochondrially encoded cytochrome c oxidase III
chr21_-_35016231 0.03 ENST00000438788.1
 CRYZL1
 crystallin, zeta (quinone reductase)-like 1
chrX_+_100645812 0.03 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
 RPL36A
RPL36A-HNRNPH2
 ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr13_+_36050881 0.03 ENST00000537702.1
 NBEA
 neurobeachin
chr13_+_31191920 0.03 ENST00000255304.4
 USPL1
 ubiquitin specific peptidase like 1
chr19_-_51537982 0.03 ENST00000525263.1
 KLK12
 kallikrein-related peptidase 12
chr17_-_55822653 0.03 ENST00000299415.2
 AC007431.1
 coiled-coil domain containing 182
chr15_+_96869165 0.03 ENST00000421109.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr3_-_170626418 0.03 ENST00000474096.1
ENST00000295822.2
 EIF5A2
 eukaryotic translation initiation factor 5A2
chr1_+_26644441 0.03 ENST00000374213.2
 CD52
 CD52 molecule
chr5_+_63461642 0.03 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
 RNF180
 ring finger protein 180
chr1_-_151965048 0.02 ENST00000368809.1
 S100A10
 S100 calcium binding protein A10
chr10_-_48390973 0.02 ENST00000224600.4
 RBP3
 retinol binding protein 3, interstitial
chr16_-_58004992 0.02 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
 CNGB1
 cyclic nucleotide gated channel beta 1
chr5_+_161494770 0.02 ENST00000414552.2
ENST00000361925.4
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr19_+_18208603 0.02 ENST00000262811.6
 MAST3
 microtubule associated serine/threonine kinase 3
chr15_-_31453157 0.02 ENST00000559177.1
ENST00000558445.1
 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
chr19_-_48547294 0.02 ENST00000293255.2
 CABP5
 calcium binding protein 5
chrX_+_100646190 0.02 ENST00000471855.1
 RPL36A
 ribosomal protein L36a
chr15_+_79603404 0.02 ENST00000299705.5
 TMED3
 transmembrane emp24 protein transport domain containing 3
chr4_+_129730839 0.02 ENST00000511647.1
 PHF17
 jade family PHD finger 1
chr13_-_62001982 0.02 ENST00000409186.1
 PCDH20
 protocadherin 20
chr2_+_183943464 0.02 ENST00000354221.4
 DUSP19
 dual specificity phosphatase 19
chr1_+_202431859 0.02 ENST00000391959.3
ENST00000367270.4
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr10_-_94003003 0.02 ENST00000412050.4
 CPEB3
 cytoplasmic polyadenylation element binding protein 3
chr20_-_34330129 0.02 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
 RBM39
 RNA binding motif protein 39
chr3_+_130650738 0.02 ENST00000504612.1
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr22_-_41258074 0.02 ENST00000307221.4
 DNAJB7
 DnaJ (Hsp40) homolog, subfamily B, member 7
chr1_+_87380299 0.02 ENST00000370551.4
ENST00000370550.5
 HS2ST1
 heparan sulfate 2-O-sulfotransferase 1
chr2_-_30144432 0.02 ENST00000389048.3
 ALK
 anaplastic lymphoma receptor tyrosine kinase
chr6_-_139613269 0.02 ENST00000358430.3
 TXLNB
 taxilin beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.0 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins