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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PAX1_PAX9

Z-value: 0.31

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Transcription factors associated with PAX1_PAX9

Gene Symbol Gene ID Gene Info
ENSG00000125813.9 PAX1
ENSG00000198807.8 PAX9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX9hg19_v2_chr14_+_37126765_371267990.442.8e-01Click!
PAX1hg19_v2_chr20_+_21686290_216863110.304.7e-01Click!

Activity profile of PAX1_PAX9 motif

Sorted Z-values of PAX1_PAX9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX1_PAX9

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_123747979 0.41 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr4_+_123747834 0.35 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr5_-_133747589 0.22 ENST00000458198.2
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr8_+_84824920 0.21 ENST00000523678.1
RP11-120I21.2
RP11-120I21.2
chr5_-_133747551 0.17 ENST00000395009.3
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr2_-_207629997 0.15 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chrX_-_153707545 0.14 ENST00000357360.4
LAGE3
L antigen family, member 3
chr7_-_19157248 0.14 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chrX_-_153707246 0.14 ENST00000407062.1
LAGE3
L antigen family, member 3
chr1_-_162838551 0.14 ENST00000367910.1
ENST00000367912.2
ENST00000367911.2
C1orf110
chromosome 1 open reading frame 110
chr19_-_40791211 0.12 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr8_-_121824374 0.11 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr2_+_119699864 0.10 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr8_-_125384927 0.10 ENST00000297632.6
TMEM65
transmembrane protein 65
chr2_-_207630033 0.09 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr5_+_133842243 0.08 ENST00000515627.2
AC005355.2
AC005355.2
chr19_-_18995029 0.08 ENST00000596048.1
CERS1
ceramide synthase 1
chr7_-_144533074 0.08 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr2_-_175712270 0.08 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr9_+_33795533 0.07 ENST00000379405.3
PRSS3
protease, serine, 3
chr9_+_33750667 0.07 ENST00000457896.1
ENST00000342836.4
ENST00000429677.3
PRSS3
protease, serine, 3
chr1_+_26759295 0.07 ENST00000430232.1
DHDDS
dehydrodolichyl diphosphate synthase
chr10_-_99393208 0.07 ENST00000307450.6
MORN4
MORN repeat containing 4
chr9_+_33750515 0.07 ENST00000361005.5
PRSS3
protease, serine, 3
chr13_+_98086445 0.06 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr5_+_72251857 0.06 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
FCHO2
FCH domain only 2
chr20_-_17641097 0.06 ENST00000246043.4
RRBP1
ribosome binding protein 1
chr17_+_39969183 0.05 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr12_-_101801505 0.05 ENST00000539055.1
ENST00000551688.1
ENST00000551671.1
ENST00000261636.8
ARL1
ADP-ribosylation factor-like 1
chr17_-_7137582 0.05 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr1_+_26758790 0.05 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
DHDDS
dehydrodolichyl diphosphate synthase
chr17_-_3461092 0.04 ENST00000301365.4
ENST00000572519.1
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr6_-_137366163 0.04 ENST00000367748.1
IL20RA
interleukin 20 receptor, alpha
chr19_+_14184370 0.04 ENST00000590772.1
hsa-mir-1199
hsa-mir-1199
chr10_-_99393242 0.04 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN4
MORN repeat containing 4
chr7_+_142457315 0.04 ENST00000486171.1
ENST00000311737.7
PRSS1
protease, serine, 1 (trypsin 1)
chr14_-_69261310 0.04 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr9_-_131418944 0.04 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
WDR34
WD repeat domain 34
chr9_+_96793076 0.04 ENST00000375360.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr6_+_3118926 0.04 ENST00000380379.5
BPHL
biphenyl hydrolase-like (serine hydrolase)
chr18_-_33077556 0.03 ENST00000589273.1
ENST00000586489.1
INO80C
INO80 complex subunit C
chr16_+_67197288 0.03 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chr15_+_63569731 0.03 ENST00000261879.5
APH1B
APH1B gamma secretase subunit
chr1_-_213031418 0.03 ENST00000356684.3
ENST00000426161.1
ENST00000424044.1
FLVCR1-AS1
FLVCR1 antisense RNA 1 (head to head)
chr4_+_619386 0.03 ENST00000496514.1
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr8_-_101965559 0.02 ENST00000353245.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr10_-_43904608 0.02 ENST00000337970.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr3_+_15247686 0.02 ENST00000253693.2
CAPN7
calpain 7
chr13_+_21141208 0.02 ENST00000351808.5
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr18_-_47017956 0.02 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr6_+_159291090 0.02 ENST00000367073.4
ENST00000608817.1
C6orf99
chromosome 6 open reading frame 99
chr13_+_21141270 0.02 ENST00000319980.6
ENST00000537103.1
ENST00000389373.3
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr18_+_39766626 0.02 ENST00000593234.1
ENST00000585627.1
ENST00000591199.1
ENST00000586990.1
ENST00000593051.1
ENST00000593316.1
ENST00000591381.1
ENST00000585639.1
ENST00000589068.1
LINC00907
long intergenic non-protein coding RNA 907
chr6_+_159290917 0.02 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr4_-_171011084 0.02 ENST00000337664.4
AADAT
aminoadipate aminotransferase
chr10_+_82297658 0.02 ENST00000339284.2
SH2D4B
SH2 domain containing 4B
chr11_+_61522844 0.01 ENST00000265460.5
MYRF
myelin regulatory factor
chr19_-_52148798 0.01 ENST00000534261.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr8_+_39792474 0.01 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr4_-_171011323 0.01 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
AADAT
aminoadipate aminotransferase
chr2_-_162931052 0.01 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr6_-_137494775 0.01 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
IL22RA2
interleukin 22 receptor, alpha 2
chr9_-_21142144 0.01 ENST00000380229.2
IFNW1
interferon, omega 1
chr1_+_160121356 0.01 ENST00000368081.4
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chrX_+_148622513 0.01 ENST00000393985.3
ENST00000423421.1
ENST00000423540.2
ENST00000434353.2
ENST00000514208.1
CXorf40A
chromosome X open reading frame 40A
chr11_+_6947720 0.01 ENST00000414517.2
ZNF215
zinc finger protein 215
chr14_+_39703112 0.01 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr19_-_40791302 0.01 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr3_-_25824925 0.00 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1
N-glycanase 1
chr3_-_25824872 0.00 ENST00000308710.5
NGLY1
N-glycanase 1
chr15_+_63569785 0.00 ENST00000380343.4
ENST00000560353.1
APH1B
APH1B gamma secretase subunit
chr18_-_47018769 0.00 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.1 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network