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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for POU4F2

Z-value: 0.29

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Transcription factors associated with POU4F2

Gene Symbol Gene ID Gene Info
POU4F2
ENSG00000151615.3 POU4F2

Activity profile of POU4F2 motif

Sorted Z-values of POU4F2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_116444371 0.14 ENST00000533213.2
ENST00000369252.4
 ABLIM1
 actin binding LIM protein 1
chr1_+_160370344 0.11 ENST00000368061.2
 VANGL2
 VANGL planar cell polarity protein 2
chr6_-_25874440 0.10 ENST00000361703.6
ENST00000397060.4
 SLC17A3
 solute carrier family 17 (organic anion transporter), member 3
chr7_-_81399411 0.09 ENST00000423064.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_10521574 0.07 ENST00000495262.1
 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr17_+_48243352 0.07 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
 SGCA
 sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr5_-_134914673 0.06 ENST00000512158.1
 CXCL14
 chemokine (C-X-C motif) ligand 14
chr2_-_70780572 0.06 ENST00000450929.1
 TGFA
 transforming growth factor, alpha
chr8_-_18541603 0.06 ENST00000428502.2
 PSD3
 pleckstrin and Sec7 domain containing 3
chr14_+_97925151 0.06 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
 CTD-2506J14.1
 CTD-2506J14.1
chr20_+_48909240 0.05 ENST00000371639.3
 RP11-290F20.1
 RP11-290F20.1
chr18_+_74240610 0.05 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
 LINC00908
 long intergenic non-protein coding RNA 908
chrX_+_139791917 0.05 ENST00000607004.1
ENST00000370535.3
 LINC00632
 long intergenic non-protein coding RNA 632
chr4_-_123542224 0.05 ENST00000264497.3
 IL21
 interleukin 21
chr11_-_125550764 0.04 ENST00000527795.1
 ACRV1
 acrosomal vesicle protein 1
chr3_+_63428752 0.04 ENST00000295894.5
 SYNPR
 synaptoporin
chr7_-_81399355 0.04 ENST00000457544.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr9_+_125132803 0.04 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_+_18086392 0.04 ENST00000541285.1
 ALKBH5
 alkB, alkylation repair homolog 5 (E. coli)
chr4_+_144354644 0.04 ENST00000512843.1
 GAB1
 GRB2-associated binding protein 1
chr20_+_56136136 0.04 ENST00000319441.4
ENST00000543666.1
 PCK1
 phosphoenolpyruvate carboxykinase 1 (soluble)
chr1_-_44482979 0.04 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_-_107729887 0.04 ENST00000525815.1
 SLC35F2
 solute carrier family 35, member F2
chr1_-_193028632 0.03 ENST00000421683.1
 UCHL5
 ubiquitin carboxyl-terminal hydrolase L5
chr5_-_87516448 0.03 ENST00000511218.1
 TMEM161B
 transmembrane protein 161B
chr6_+_130339710 0.03 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
chr3_-_79816965 0.03 ENST00000464233.1
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr14_+_55221541 0.03 ENST00000555192.1
 SAMD4A
 sterile alpha motif domain containing 4A
chr7_-_25268104 0.03 ENST00000222674.2
 NPVF
 neuropeptide VF precursor
chr2_-_158300556 0.03 ENST00000264192.3
 CYTIP
 cytohesin 1 interacting protein
chr1_-_193028426 0.03 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
 UCHL5
 ubiquitin carboxyl-terminal hydrolase L5
chr10_-_73848531 0.03 ENST00000373109.2
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr5_+_66300446 0.03 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr5_+_154393260 0.03 ENST00000435029.4
 KIF4B
 kinesin family member 4B
chr21_+_17442799 0.03 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr1_-_182641367 0.03 ENST00000508450.1
 RGS8
 regulator of G-protein signaling 8
chr19_-_36304201 0.02 ENST00000301175.3
 PRODH2
 proline dehydrogenase (oxidase) 2
chr7_-_81399329 0.02 ENST00000453411.1
ENST00000444829.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399438 0.02 ENST00000222390.5
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr4_+_78432907 0.02 ENST00000286758.4
 CXCL13
 chemokine (C-X-C motif) ligand 13
chr10_-_73848086 0.02 ENST00000536168.1
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr8_+_22857048 0.02 ENST00000251822.6
 RHOBTB2
 Rho-related BTB domain containing 2
chr3_-_51909600 0.02 ENST00000446461.1
 IQCF5
 IQ motif containing F5
chr7_+_142982023 0.02 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
 TMEM139
 transmembrane protein 139
chr8_+_7682694 0.02 ENST00000335186.2
 DEFB106A
 defensin, beta 106A
chr1_-_193028621 0.02 ENST00000367455.4
ENST00000367454.1
 UCHL5
 ubiquitin carboxyl-terminal hydrolase L5
chr20_+_11008408 0.02 ENST00000378252.1
 C20orf187
 chromosome 20 open reading frame 187
chr11_-_125550726 0.02 ENST00000315608.3
ENST00000530048.1
 ACRV1
 acrosomal vesicle protein 1
chr11_+_31531291 0.02 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
 ELP4
 elongator acetyltransferase complex subunit 4
chr12_-_89746173 0.02 ENST00000308385.6
 DUSP6
 dual specificity phosphatase 6
chr6_+_151042224 0.02 ENST00000358517.2
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr4_-_47983519 0.02 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1
 cyclic nucleotide gated channel alpha 1
chr14_-_51027838 0.02 ENST00000555216.1
 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
chr6_-_89927151 0.02 ENST00000454853.2
 GABRR1
 gamma-aminobutyric acid (GABA) A receptor, rho 1
chr4_+_76481258 0.02 ENST00000311623.4
ENST00000435974.2
 C4orf26
 chromosome 4 open reading frame 26
chr9_+_77230499 0.02 ENST00000396204.2
 RORB
 RAR-related orphan receptor B
chr17_-_9929581 0.02 ENST00000437099.2
ENST00000396115.2
 GAS7
 growth arrest-specific 7
chr4_-_10686373 0.02 ENST00000442825.2
 CLNK
 cytokine-dependent hematopoietic cell linker
chr16_+_28505955 0.02 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
 APOBR
 apolipoprotein B receptor
chr16_-_20416053 0.01 ENST00000302451.4
 PDILT
 protein disulfide isomerase-like, testis expressed
chr9_+_125133315 0.01 ENST00000223423.4
ENST00000362012.2
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_+_68100989 0.01 ENST00000585558.1
ENST00000392670.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr15_-_98417780 0.01 ENST00000503874.3
 LINC00923
 long intergenic non-protein coding RNA 923
chr8_+_50824233 0.01 ENST00000522124.1
 SNTG1
 syntrophin, gamma 1
chr5_-_140998481 0.01 ENST00000518047.1
 DIAPH1
 diaphanous-related formin 1
chr12_-_118797475 0.01 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
 TAOK3
 TAO kinase 3
chr17_-_79623597 0.01 ENST00000574024.1
ENST00000331056.5
 PDE6G
 phosphodiesterase 6G, cGMP-specific, rod, gamma
chr9_-_14308004 0.01 ENST00000493697.1
 NFIB
 nuclear factor I/B
chr21_+_17443434 0.01 ENST00000400178.2
 LINC00478
 long intergenic non-protein coding RNA 478
chr3_-_138048682 0.01 ENST00000383180.2
 NME9
 NME/NM23 family member 9
chr6_-_138820624 0.01 ENST00000343505.5
 NHSL1
 NHS-like 1
chr8_-_7287870 0.01 ENST00000318124.3
 DEFB103B
 defensin, beta 103B
chr8_+_7738726 0.01 ENST00000314357.3
 DEFB103A
 defensin, beta 103A
chr8_-_131399110 0.01 ENST00000521426.1
 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr13_-_36050819 0.01 ENST00000379919.4
 MAB21L1
 mab-21-like 1 (C. elegans)
chr6_-_139308777 0.01 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
 REPS1
 RALBP1 associated Eps domain containing 1
chr2_+_101179152 0.01 ENST00000264254.6
 PDCL3
 phosducin-like 3
chr4_-_10686475 0.01 ENST00000226951.6
 CLNK
 cytokine-dependent hematopoietic cell linker
chr3_+_115342349 0.01 ENST00000393780.3
 GAP43
 growth associated protein 43
chr20_-_50418972 0.01 ENST00000395997.3
 SALL4
 spalt-like transcription factor 4
chr13_+_46039037 0.01 ENST00000349995.5
 COG3
 component of oligomeric golgi complex 3
chr20_-_50418947 0.01 ENST00000371539.3
 SALL4
 spalt-like transcription factor 4
chr2_+_191792376 0.01 ENST00000409428.1
ENST00000409215.1
 GLS
 glutaminase
chr1_+_40506392 0.01 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
chr21_+_17443521 0.01 ENST00000456342.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr19_-_7698599 0.01 ENST00000311069.5
 PCP2
 Purkinje cell protein 2
chr20_-_50419055 0.01 ENST00000217086.4
 SALL4
 spalt-like transcription factor 4
chr5_-_140998616 0.00 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
 DIAPH1
 diaphanous-related formin 1
chr14_+_22356029 0.00 ENST00000390437.2
 TRAV12-2
 T cell receptor alpha variable 12-2
chr4_-_169401628 0.00 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
 DDX60L
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr2_-_198540719 0.00 ENST00000295049.4
 RFTN2
 raftlin family member 2
chr1_+_193028552 0.00 ENST00000400968.2
ENST00000432079.1
 TROVE2
 TROVE domain family, member 2
chrX_-_133931164 0.00 ENST00000370790.1
ENST00000298090.6
 FAM122B
 family with sequence similarity 122B
chr16_+_19422035 0.00 ENST00000381414.4
ENST00000396229.2
 TMC5
 transmembrane channel-like 5
chr4_+_159443024 0.00 ENST00000448688.2
 RXFP1
 relaxin/insulin-like family peptide receptor 1
chr16_+_19421803 0.00 ENST00000541464.1
 TMC5
 transmembrane channel-like 5
chr11_+_73498898 0.00 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
 MRPL48
 mitochondrial ribosomal protein L48
chr4_+_169418195 0.00 ENST00000261509.6
ENST00000335742.7
 PALLD
 palladin, cytoskeletal associated protein
chr4_+_169013666 0.00 ENST00000359299.3
 ANXA10
 annexin A10
chrX_-_18690210 0.00 ENST00000379984.3
 RS1
 retinoschisin 1
chrX_-_106146547 0.00 ENST00000276173.4
ENST00000411805.1
 RIPPLY1
 ripply transcriptional repressor 1
chr4_+_159443090 0.00 ENST00000343542.5
ENST00000470033.1
 RXFP1
 relaxin/insulin-like family peptide receptor 1
chr10_+_18549645 0.00 ENST00000396576.2
 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
chr11_-_41481135 0.00 ENST00000528697.1
ENST00000530763.1
 LRRC4C
 leucine rich repeat containing 4C
chr14_+_42077552 0.00 ENST00000554120.1
 LRFN5
 leucine rich repeat and fibronectin type III domain containing 5
chr4_+_169418255 0.00 ENST00000505667.1
ENST00000511948.1
 PALLD
 palladin, cytoskeletal associated protein
chr10_-_99205607 0.00 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
 EXOSC1
 exosome component 1
chr6_+_118869452 0.00 ENST00000357525.5
 PLN
 phospholamban

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.0 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060187 cell pole(GO:0060187)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)