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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for POU5F1_POU2F3

Z-value: 0.49

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
POU5F1
ENSG00000204531.11 POU5F1
POU2F3
ENSG00000137709.5 POU2F3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg19_v2_chr6_-_31138439_311384750.472.4e-01Click!
POU2F3hg19_v2_chr11_+_120107344_120107351-0.118.0e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_44123734 0.43 ENST00000598676.1
 ZNF428
 zinc finger protein 428
chr1_+_61547405 0.39 ENST00000371189.4
 NFIA
 nuclear factor I/A
chr12_+_113344755 0.38 ENST00000550883.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_90060377 0.37 ENST00000436451.2
 IGKV6D-21
 immunoglobulin kappa variable 6D-21 (non-functional)
chr19_-_44124019 0.36 ENST00000300811.3
 ZNF428
 zinc finger protein 428
chr1_+_61542922 0.36 ENST00000407417.3
 NFIA
 nuclear factor I/A
chr12_-_95941987 0.34 ENST00000537435.2
 USP44
 ubiquitin specific peptidase 44
chr7_-_141673573 0.33 ENST00000547270.1
 TAS2R38
 taste receptor, type 2, member 38
chr19_-_50143452 0.33 ENST00000246792.3
 RRAS
 related RAS viral (r-ras) oncogene homolog
chr2_+_90108504 0.31 ENST00000390271.2
 IGKV6D-41
 immunoglobulin kappa variable 6D-41 (non-functional)
chr10_-_98031310 0.29 ENST00000427367.2
ENST00000413476.2
 BLNK
 B-cell linker
chr13_-_20110902 0.28 ENST00000390680.2
ENST00000382977.4
ENST00000382975.4
ENST00000457266.2
 TPTE2
 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr10_-_98031265 0.28 ENST00000224337.5
ENST00000371176.2
 BLNK
 B-cell linker
chrX_-_106960285 0.27 ENST00000503515.1
ENST00000372397.2
 TSC22D3
 TSC22 domain family, member 3
chr5_+_119867159 0.25 ENST00000505123.1
 PRR16
 proline rich 16
chrX_+_80457442 0.25 ENST00000373212.5
 SH3BGRL
 SH3 domain binding glutamic acid-rich protein like
chr6_-_35656685 0.24 ENST00000539068.1
ENST00000540787.1
 FKBP5
 FK506 binding protein 5
chr12_+_7052974 0.24 ENST00000544681.1
ENST00000537087.1
 C12orf57
 chromosome 12 open reading frame 57
chr2_+_189839046 0.24 ENST00000304636.3
ENST00000317840.5
 COL3A1
 collagen, type III, alpha 1
chr3_-_149293990 0.24 ENST00000472417.1
 WWTR1
 WW domain containing transcription regulator 1
chr6_+_26251835 0.23 ENST00000356350.2
 HIST1H2BH
 histone cluster 1, H2bh
chr12_+_7053172 0.23 ENST00000229281.5
 C12orf57
 chromosome 12 open reading frame 57
chr6_-_35656712 0.22 ENST00000357266.4
ENST00000542713.1
 FKBP5
 FK506 binding protein 5
chr14_-_92413353 0.22 ENST00000556154.1
 FBLN5
 fibulin 5
chr2_-_48468122 0.21 ENST00000447571.1
 AC079807.4
 AC079807.4
chr10_-_105452917 0.21 ENST00000427662.2
 SH3PXD2A
 SH3 and PX domains 2A
chr2_-_89459813 0.21 ENST00000390256.2
 IGKV6-21
 immunoglobulin kappa variable 6-21 (non-functional)
chr12_+_7053228 0.21 ENST00000540506.2
 C12orf57
 chromosome 12 open reading frame 57
chr1_+_61547894 0.20 ENST00000403491.3
 NFIA
 nuclear factor I/A
chr5_-_172198190 0.20 ENST00000239223.3
 DUSP1
 dual specificity phosphatase 1
chr5_-_169626104 0.20 ENST00000520275.1
ENST00000506431.2
 CTB-27N1.1
 CTB-27N1.1
chr11_+_111126707 0.19 ENST00000280325.4
 C11orf53
 chromosome 11 open reading frame 53
chr5_-_111091948 0.19 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr17_-_7307358 0.19 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
 TMEM256
TMEM256-PLSCR3
 transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr11_-_64084959 0.19 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
 TRMT112
 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr11_-_64085533 0.19 ENST00000544844.1
 TRMT112
 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr16_+_10971037 0.18 ENST00000324288.8
ENST00000381835.5
 CIITA
 class II, major histocompatibility complex, transactivator
chr22_+_22707260 0.18 ENST00000390293.1
 IGLV5-48
 immunoglobulin lambda variable 5-48 (non-functional)
chr16_-_33647696 0.18 ENST00000558425.1
ENST00000569103.2
 RP11-812E19.9
 Uncharacterized protein
chr6_+_50061315 0.18 ENST00000415106.1
 RP11-397G17.1
 RP11-397G17.1
chr11_-_133715394 0.18 ENST00000299140.3
ENST00000532889.1
 SPATA19
 spermatogenesis associated 19
chr22_-_27456361 0.18 ENST00000453934.1
 CTA-992D9.6
 CTA-992D9.6
chr16_-_30107491 0.18 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
 YPEL3
 yippee-like 3 (Drosophila)
chr14_-_106845789 0.17 ENST00000390617.2
 IGHV3-35
 immunoglobulin heavy variable 3-35 (non-functional)
chr7_-_135612198 0.17 ENST00000589735.1
 LUZP6
 leucine zipper protein 6
chr7_-_56101826 0.17 ENST00000421626.1
 PSPH
 phosphoserine phosphatase
chr1_-_243326612 0.17 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
 CEP170
 centrosomal protein 170kDa
chr17_-_10707410 0.16 ENST00000581851.1
 LINC00675
 long intergenic non-protein coding RNA 675
chr19_+_17337406 0.16 ENST00000597836.1
 OCEL1
 occludin/ELL domain containing 1
chr10_+_124907638 0.16 ENST00000339992.3
 HMX2
 H6 family homeobox 2
chrX_-_80457385 0.16 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
 HMGN5
 high mobility group nucleosome binding domain 5
chr2_-_45795145 0.16 ENST00000535761.1
 SRBD1
 S1 RNA binding domain 1
chr19_+_3572758 0.16 ENST00000416526.1
 HMG20B
 high mobility group 20B
chr19_+_17337007 0.16 ENST00000215061.4
 OCEL1
 occludin/ELL domain containing 1
chr14_+_55033815 0.16 ENST00000554335.1
 SAMD4A
 sterile alpha motif domain containing 4A
chr19_+_17337027 0.16 ENST00000601529.1
ENST00000600232.1
 OCEL1
 occludin/ELL domain containing 1
chr20_+_33292068 0.15 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
 TP53INP2
 tumor protein p53 inducible nuclear protein 2
chr4_+_124320665 0.15 ENST00000394339.2
 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr5_-_111092873 0.15 ENST00000509025.1
ENST00000515855.1
 NREP
 neuronal regeneration related protein
chr3_-_139396560 0.15 ENST00000514703.1
ENST00000511444.1
 NMNAT3
 nicotinamide nucleotide adenylyltransferase 3
chr16_+_33020496 0.15 ENST00000565407.2
 IGHV3OR16-8
 immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr6_+_27114861 0.15 ENST00000377459.1
 HIST1H2AH
 histone cluster 1, H2ah
chr14_-_92413727 0.15 ENST00000267620.10
 FBLN5
 fibulin 5
chr4_+_184020398 0.15 ENST00000403733.3
ENST00000378925.3
 WWC2
 WW and C2 domain containing 2
chr2_+_68962014 0.15 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr14_-_92414055 0.14 ENST00000342058.4
 FBLN5
 fibulin 5
chr17_+_43213004 0.14 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
 ACBD4
 acyl-CoA binding domain containing 4
chr1_-_27701307 0.14 ENST00000270879.4
ENST00000354982.2
 FCN3
 ficolin (collagen/fibrinogen domain containing) 3
chr19_-_893200 0.14 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
 MED16
 mediator complex subunit 16
chr14_-_106586656 0.14 ENST00000390602.2
 IGHV3-13
 immunoglobulin heavy variable 3-13
chr14_+_22964877 0.14 ENST00000390494.1
 TRAJ43
 T cell receptor alpha joining 43
chr2_+_233734994 0.14 ENST00000331342.2
 C2orf82
 chromosome 2 open reading frame 82
chr6_+_26183958 0.14 ENST00000356530.3
 HIST1H2BE
 histone cluster 1, H2be
chr12_-_95945246 0.13 ENST00000258499.3
 USP44
 ubiquitin specific peptidase 44
chr19_+_17337473 0.13 ENST00000598068.1
 OCEL1
 occludin/ELL domain containing 1
chr1_-_94586651 0.13 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr2_+_114163945 0.13 ENST00000453673.3
 IGKV1OR2-108
 immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr1_+_32666188 0.13 ENST00000421922.2
 CCDC28B
 coiled-coil domain containing 28B
chr17_-_79620721 0.13 ENST00000571004.1
 PDE6G
 phosphodiesterase 6G, cGMP-specific, rod, gamma
chr2_-_188419200 0.13 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr17_+_55334364 0.13 ENST00000322684.3
ENST00000579590.1
 MSI2
 musashi RNA-binding protein 2
chr5_+_54398463 0.13 ENST00000274306.6
 GZMA
 granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr1_-_23886285 0.13 ENST00000374561.5
 ID3
 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chrX_-_101098171 0.13 ENST00000473265.2
 NXF5
 nuclear RNA export factor 5
chr12_-_31479107 0.13 ENST00000542983.1
 FAM60A
 family with sequence similarity 60, member A
chr17_-_14683517 0.13 ENST00000379640.1
 AC005863.1
 AC005863.1
chr1_+_164528866 0.13 ENST00000420696.2
 PBX1
 pre-B-cell leukemia homeobox 1
chr12_-_91574142 0.13 ENST00000547937.1
 DCN
 decorin
chr7_-_14029283 0.12 ENST00000433547.1
ENST00000405192.2
 ETV1
 ets variant 1
chr3_-_126327398 0.12 ENST00000383572.2
 TXNRD3NB
 thioredoxin reductase 3 neighbor
chr2_-_50574856 0.12 ENST00000342183.5
 NRXN1
 neurexin 1
chr12_-_91573132 0.12 ENST00000550563.1
ENST00000546370.1
 DCN
 decorin
chr12_-_102874102 0.12 ENST00000392905.2
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr5_-_179047881 0.12 ENST00000521173.1
 HNRNPH1
 heterogeneous nuclear ribonucleoprotein H1 (H)
chr16_+_23847267 0.12 ENST00000321728.7
 PRKCB
 protein kinase C, beta
chr6_-_33679452 0.12 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
 UQCC2
 ubiquinol-cytochrome c reductase complex assembly factor 2
chr15_-_83474806 0.12 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
 FSD2
 fibronectin type III and SPRY domain containing 2
chr21_+_43823983 0.12 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
 UBASH3A
 ubiquitin associated and SH3 domain containing A
chr19_+_11466062 0.12 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
 DKFZP761J1410
 Lipid phosphate phosphatase-related protein type 2
chr19_+_11466167 0.12 ENST00000591608.1
 DKFZP761J1410
 Lipid phosphate phosphatase-related protein type 2
chr6_-_27100529 0.12 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
 HIST1H2BJ
 histone cluster 1, H2bj
chr10_-_72141330 0.12 ENST00000395011.1
ENST00000395010.1
 LRRC20
 leucine rich repeat containing 20
chr19_-_41903161 0.12 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
 EXOSC5
 exosome component 5
chr12_+_113344811 0.12 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr20_+_17207665 0.12 ENST00000536609.1
 PCSK2
 proprotein convertase subtilisin/kexin type 2
chr2_+_89998789 0.12 ENST00000453166.2
 IGKV2D-28
 immunoglobulin kappa variable 2D-28
chr1_-_1711508 0.12 ENST00000378625.1
 NADK
 NAD kinase
chr2_-_152118352 0.12 ENST00000331426.5
 RBM43
 RNA binding motif protein 43
chr2_+_241938255 0.11 ENST00000401884.1
ENST00000405547.3
ENST00000310397.8
ENST00000342631.6
 SNED1
 sushi, nidogen and EGF-like domains 1
chr6_+_131571535 0.11 ENST00000474850.2
 AKAP7
 A kinase (PRKA) anchor protein 7
chr17_-_73127778 0.11 ENST00000578407.1
 NT5C
 5', 3'-nucleotidase, cytosolic
chr16_+_21689835 0.11 ENST00000286149.4
ENST00000388958.3
 OTOA
 otoancorin
chr15_-_83240507 0.11 ENST00000564522.1
ENST00000398592.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr2_+_27237615 0.11 ENST00000458529.1
ENST00000402218.1
 MAPRE3
 microtubule-associated protein, RP/EB family, member 3
chr14_+_79745746 0.11 ENST00000281127.7
 NRXN3
 neurexin 3
chr11_-_35547151 0.11 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
 PAMR1
 peptidase domain containing associated with muscle regeneration 1
chr14_-_106622419 0.11 ENST00000390604.2
 IGHV3-16
 immunoglobulin heavy variable 3-16 (non-functional)
chr15_-_22448819 0.11 ENST00000604066.1
 IGHV1OR15-1
 immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr11_+_64085560 0.11 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
 PRDX5
 peroxiredoxin 5
chr12_-_91576561 0.11 ENST00000547568.2
ENST00000552962.1
 DCN
 decorin
chr20_-_60982330 0.11 ENST00000279101.5
 CABLES2
 Cdk5 and Abl enzyme substrate 2
chr2_+_223916862 0.11 ENST00000604125.1
 KCNE4
 potassium voltage-gated channel, Isk-related family, member 4
chr19_-_18508396 0.11 ENST00000595840.1
ENST00000339007.3
 LRRC25
 leucine rich repeat containing 25
chr12_-_102874330 0.11 ENST00000307046.8
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr17_-_73127826 0.11 ENST00000582170.1
ENST00000245552.2
 NT5C
 5', 3'-nucleotidase, cytosolic
chr14_+_97925151 0.11 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
 CTD-2506J14.1
 CTD-2506J14.1
chr1_-_153085984 0.11 ENST00000468739.1
 SPRR2F
 small proline-rich protein 2F
chr4_+_5526883 0.10 ENST00000195455.2
 C4orf6
 chromosome 4 open reading frame 6
chr10_-_13390021 0.10 ENST00000537130.1
 SEPHS1
 selenophosphate synthetase 1
chr14_-_107095662 0.10 ENST00000390630.2
 IGHV4-61
 immunoglobulin heavy variable 4-61
chr4_+_5527117 0.10 ENST00000505296.1
 C4orf6
 chromosome 4 open reading frame 6
chr3_+_57882024 0.10 ENST00000494088.1
 SLMAP
 sarcolemma associated protein
chr5_-_179045199 0.10 ENST00000523921.1
 HNRNPH1
 heterogeneous nuclear ribonucleoprotein H1 (H)
chr1_+_220863187 0.10 ENST00000294889.5
 C1orf115
 chromosome 1 open reading frame 115
chr5_-_111092930 0.10 ENST00000257435.7
 NREP
 neuronal regeneration related protein
chr6_+_26402517 0.10 ENST00000414912.2
 BTN3A1
 butyrophilin, subfamily 3, member A1
chr6_+_27861190 0.10 ENST00000303806.4
 HIST1H2BO
 histone cluster 1, H2bo
chr11_+_313503 0.10 ENST00000528780.1
ENST00000328221.5
 IFITM1
 interferon induced transmembrane protein 1
chr9_-_116065551 0.10 ENST00000297894.5
 RNF183
 ring finger protein 183
chr16_+_19079215 0.10 ENST00000544894.2
ENST00000561858.1
 COQ7
 coenzyme Q7 homolog, ubiquinone (yeast)
chrX_+_69674943 0.10 ENST00000542398.1
 DLG3
 discs, large homolog 3 (Drosophila)
chr10_-_93392811 0.10 ENST00000238994.5
 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
chr22_-_36357671 0.10 ENST00000408983.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_185597619 0.10 ENST00000608417.1
ENST00000436955.1
 GS1-204I12.1
 GS1-204I12.1
chr1_-_116383738 0.10 ENST00000320238.3
 NHLH2
 nescient helix loop helix 2
chr20_+_361890 0.10 ENST00000449710.1
ENST00000422053.2
 TRIB3
 tribbles pseudokinase 3
chr1_+_115572415 0.10 ENST00000256592.1
 TSHB
 thyroid stimulating hormone, beta
chr8_+_70404996 0.10 ENST00000402687.4
ENST00000419716.3
 SULF1
 sulfatase 1
chr20_+_39657454 0.10 ENST00000361337.2
 TOP1
 topoisomerase (DNA) I
chr18_-_59274139 0.10 ENST00000586949.1
 RP11-879F14.2
 RP11-879F14.2
chr17_-_34257771 0.10 ENST00000394529.3
ENST00000293273.6
 RDM1
 RAD52 motif 1
chr20_+_34802295 0.10 ENST00000432603.1
 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
chr5_+_49962495 0.10 ENST00000515175.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr1_+_145524891 0.09 ENST00000369304.3
 ITGA10
 integrin, alpha 10
chr2_-_89521942 0.09 ENST00000482769.1
 IGKV2-28
 immunoglobulin kappa variable 2-28
chr3_+_57881966 0.09 ENST00000495364.1
 SLMAP
 sarcolemma associated protein
chr1_-_8000872 0.09 ENST00000377507.3
 TNFRSF9
 tumor necrosis factor receptor superfamily, member 9
chr13_-_103053946 0.09 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr3_+_173116225 0.09 ENST00000457714.1
 NLGN1
 neuroligin 1
chr12_-_31479045 0.09 ENST00000539409.1
ENST00000395766.1
 FAM60A
 family with sequence similarity 60, member A
chr4_+_120056939 0.09 ENST00000307128.5
 MYOZ2
 myozenin 2
chr1_+_156119466 0.09 ENST00000414683.1
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr14_-_106610852 0.09 ENST00000390603.2
 IGHV3-15
 immunoglobulin heavy variable 3-15
chr15_-_63448973 0.09 ENST00000462430.1
 RPS27L
 ribosomal protein S27-like
chr1_+_175036966 0.09 ENST00000239462.4
 TNN
 tenascin N
chr10_-_91403625 0.09 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
 PANK1
 pantothenate kinase 1
chr14_-_24553834 0.09 ENST00000397002.2
 NRL
 neural retina leucine zipper
chr7_+_64363625 0.09 ENST00000476120.1
ENST00000319636.5
ENST00000545510.1
 ZNF273
 zinc finger protein 273
chr6_+_131958436 0.09 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
 ENPP3
 ectonucleotide pyrophosphatase/phosphodiesterase 3
chr16_+_19079311 0.09 ENST00000569127.1
 COQ7
 coenzyme Q7 homolog, ubiquinone (yeast)
chr1_+_59775752 0.09 ENST00000371212.1
 FGGY
 FGGY carbohydrate kinase domain containing
chrX_+_12993202 0.09 ENST00000451311.2
ENST00000380636.1
 TMSB4X
 thymosin beta 4, X-linked
chr10_-_10836865 0.09 ENST00000446372.2
 SFTA1P
 surfactant associated 1, pseudogene
chr9_-_116062045 0.09 ENST00000478815.1
 RNF183
 ring finger protein 183
chr12_-_91576750 0.09 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
 DCN
 decorin
chr2_-_188419078 0.09 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_-_15586238 0.09 ENST00000462989.2
 DTNBP1
 dystrobrevin binding protein 1
chr18_+_63417864 0.09 ENST00000536984.2
 CDH7
 cadherin 7, type 2
chr4_+_70916119 0.09 ENST00000246896.3
ENST00000511674.1
 HTN1
 histatin 1
chr15_-_88799384 0.09 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
 NTRK3
 neurotrophic tyrosine kinase, receptor, type 3
chr6_-_43655511 0.09 ENST00000372133.3
ENST00000372116.1
ENST00000427312.1
 MRPS18A
 mitochondrial ribosomal protein S18A
chr14_-_107083690 0.09 ENST00000455737.1
ENST00000390629.2
 IGHV4-59
 immunoglobulin heavy variable 4-59
chr1_-_149783914 0.09 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
 HIST2H2BF
 histone cluster 2, H2bf
chr17_-_19651668 0.09 ENST00000494157.2
ENST00000225740.6
 ALDH3A1
 aldehyde dehydrogenase 3 family, member A1
chr10_-_116286563 0.09 ENST00000369253.2
 ABLIM1
 actin binding LIM protein 1
chr1_-_150849047 0.08 ENST00000354396.2
ENST00000505755.1
 ARNT
 aryl hydrocarbon receptor nuclear translocator
chr7_+_142982023 0.08 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
 TMEM139
 transmembrane protein 139
chr8_-_101348408 0.08 ENST00000519527.1
ENST00000522369.1
 RNF19A
 ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr12_-_123921256 0.08 ENST00000280571.8
 RILPL2
 Rab interacting lysosomal protein-like 2
chr11_-_73687997 0.08 ENST00000545212.1
 UCP2
 uncoupling protein 2 (mitochondrial, proton carrier)
chr3_+_69928256 0.08 ENST00000394355.2
 MITF
 microphthalmia-associated transcription factor
chr1_+_149822620 0.08 ENST00000369159.2
 HIST2H2AA4
 histone cluster 2, H2aa4
chr5_-_173043591 0.08 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
 BOD1
 biorientation of chromosomes in cell division 1
chrX_-_24665208 0.08 ENST00000356768.4
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chrX_+_12993336 0.08 ENST00000380635.1
 TMSB4X
 thymosin beta 4, X-linked
chr10_+_115939008 0.08 ENST00000369282.1
ENST00000251864.2
ENST00000369281.2
ENST00000422662.1
 TDRD1
 tudor domain containing 1
chr20_+_34556488 0.08 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
 CNBD2
 cyclic nucleotide binding domain containing 2
chr10_+_6779326 0.08 ENST00000417112.1
 RP11-554I8.2
 RP11-554I8.2
chr19_+_56111680 0.08 ENST00000301073.3
 ZNF524
 zinc finger protein 524
chr22_-_19435209 0.08 ENST00000546308.1
ENST00000541063.1
ENST00000399568.1
ENST00000333059.5
 HIRA
C22orf39
 histone cell cycle regulator
chromosome 22 open reading frame 39

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.0 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.2 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 1.0 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.7 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.1 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.3 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.0 GO:0072278 metanephric comma-shaped body morphogenesis(GO:0072278)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.0 GO:0046839 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.0 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
0.0 0.0 GO:0061183 negative regulation of mesodermal cell fate specification(GO:0042662) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.0 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.0 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.0 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0071953 elastic fiber(GO:0071953)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.0 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0016918 retinoid binding(GO:0005501) retinal binding(GO:0016918) isoprenoid binding(GO:0019840) retinol binding(GO:0019841)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.0 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.0 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.0 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors