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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PPARD

Z-value: 0.27

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Transcription factors associated with PPARD

Gene Symbol Gene ID Gene Info
ENSG00000112033.9 PPARD

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARDhg19_v2_chr6_+_35310391_353104100.667.2e-02Click!

Activity profile of PPARD motif

Sorted Z-values of PPARD motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARD

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_43885252 0.45 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43985084 0.44 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr19_-_10687907 0.32 ENST00000589348.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_-_10687948 0.31 ENST00000592285.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_-_10687983 0.28 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr17_+_48610074 0.20 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr2_+_206547215 0.19 ENST00000360409.3
ENST00000540178.1
ENST00000540841.1
ENST00000355117.4
ENST00000450507.1
ENST00000417189.1
NRP2
neuropilin 2
chr12_-_53320245 0.17 ENST00000552150.1
KRT8
keratin 8
chr2_+_95940186 0.13 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
PROM2
prominin 2
chr1_+_62417957 0.12 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr11_-_119599794 0.12 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr5_-_16509101 0.11 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr1_+_156123318 0.11 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr4_+_140586922 0.10 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr17_+_37894179 0.09 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr17_-_39728303 0.08 ENST00000588431.1
ENST00000246662.4
KRT9
keratin 9
chr6_+_33172407 0.08 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr16_-_4401258 0.07 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr16_-_4401284 0.07 ENST00000318059.3
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr7_+_112090483 0.07 ENST00000403825.3
ENST00000429071.1
IFRD1
interferon-related developmental regulator 1
chr14_+_32546145 0.05 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr14_+_32546274 0.05 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr2_+_159651821 0.04 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr14_-_51561784 0.04 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr2_-_99871570 0.04 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr17_-_34270668 0.04 ENST00000293274.4
LYZL6
lysozyme-like 6
chr17_-_34270697 0.04 ENST00000585556.1
LYZL6
lysozyme-like 6
chrX_-_148571884 0.03 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr22_-_42526802 0.03 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6
chr4_-_7069760 0.03 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr12_-_95467267 0.03 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr11_-_61658853 0.03 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr22_-_29784519 0.03 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr6_-_33548006 0.03 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr15_+_75494214 0.03 ENST00000394987.4
C15orf39
chromosome 15 open reading frame 39
chr11_-_116968987 0.03 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr19_+_11546440 0.03 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr19_+_11546153 0.03 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr1_-_11107280 0.03 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr1_+_202317855 0.02 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr14_-_25045446 0.02 ENST00000216336.2
CTSG
cathepsin G
chr6_-_33547975 0.02 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr11_-_61659006 0.02 ENST00000278829.2
FADS3
fatty acid desaturase 3
chr6_+_143999072 0.02 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
PHACTR2
phosphatase and actin regulator 2
chr1_+_6511651 0.02 ENST00000434576.1
ESPN
espin
chr6_+_30295036 0.02 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr19_+_10196981 0.02 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr15_-_82555000 0.02 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1
elongation factor Tu GTP binding domain containing 1
chr11_-_45939374 0.02 ENST00000533151.1
ENST00000241041.3
PEX16
peroxisomal biogenesis factor 16
chr19_+_11546093 0.02 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr19_+_51273721 0.02 ENST00000270590.4
GPR32
G protein-coupled receptor 32
chr7_-_87342564 0.02 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr19_+_39616410 0.02 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr6_+_32006042 0.02 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr1_-_120311517 0.02 ENST00000369406.3
ENST00000544913.2
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr5_+_34757309 0.02 ENST00000397449.1
RAI14
retinoic acid induced 14
chr1_+_55107449 0.02 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
MROH7
maestro heat-like repeat family member 7
chr6_+_32006159 0.01 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_-_159313214 0.01 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148
coiled-coil domain containing 148
chr15_+_82555125 0.01 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr21_+_27107672 0.01 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr12_-_109219937 0.01 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr6_+_142468383 0.01 ENST00000367621.1
ENST00000452973.2
VTA1
vesicle (multivesicular body) trafficking 1
chr7_+_143174966 0.01 ENST00000408916.1
TAS2R41
taste receptor, type 2, member 41
chr16_-_74808710 0.01 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr2_+_219433588 0.01 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr11_+_64073699 0.01 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr6_+_43266063 0.01 ENST00000372574.3
SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr2_-_207024134 0.01 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_11863171 0.01 ENST00000376592.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr6_+_142468361 0.01 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr2_+_73441350 0.01 ENST00000389501.4
SMYD5
SMYD family member 5
chr8_-_80942061 0.01 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr8_-_80942467 0.01 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr19_-_49339080 0.01 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr1_-_197036364 0.01 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr16_-_75285380 0.00 ENST00000393420.6
ENST00000162330.5
BCAR1
breast cancer anti-estrogen resistance 1
chr1_-_29508321 0.00 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chr8_-_80942139 0.00 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
MRPS28
mitochondrial ribosomal protein S28
chr5_+_14664762 0.00 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr1_+_43855545 0.00 ENST00000372450.4
ENST00000310739.4
SZT2
seizure threshold 2 homolog (mouse)
chr1_+_202317815 0.00 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chrX_+_2746850 0.00 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression