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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PRDM1

Z-value: 0.80

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Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
PRDM1
ENSG00000057657.10 PRDM1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v2_chr6_+_106546808_106546833-0.939.0e-04Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_92919043 1.69 ENST00000327111.3
 NR2F1
 nuclear receptor subfamily 2, group F, member 1
chr8_+_97506033 1.65 ENST00000518385.1
 SDC2
 syndecan 2
chr13_+_102104980 1.60 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_8543393 0.84 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
 LMCD1
 LIM and cysteine-rich domains 1
chr6_-_167275991 0.83 ENST00000510118.1
 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167276033 0.80 ENST00000503859.1
ENST00000506565.1
 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr3_+_69915385 0.76 ENST00000314589.5
 MITF
 microphthalmia-associated transcription factor
chr17_+_41158742 0.75 ENST00000415816.2
ENST00000438323.2
 IFI35
 interferon-induced protein 35
chrX_-_118827333 0.66 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
 SEPT6
 septin 6
chr9_+_18474098 0.64 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
 ADAMTSL1
 ADAMTS-like 1
chr3_+_8543561 0.63 ENST00000397386.3
 LMCD1
 LIM and cysteine-rich domains 1
chr2_-_145275228 0.60 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr7_+_95401851 0.60 ENST00000447467.2
 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
chr4_-_100242549 0.59 ENST00000305046.8
ENST00000394887.3
 ADH1B
 alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_-_49851313 0.57 ENST00000333486.3
 UBA7
 ubiquitin-like modifier activating enzyme 7
chr8_+_77593448 0.57 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr15_-_37393406 0.56 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
 MEIS2
 Meis homeobox 2
chr8_+_77593474 0.54 ENST00000455469.2
ENST00000050961.6
 ZFHX4
 zinc finger homeobox 4
chr16_-_67970990 0.54 ENST00000358514.4
 PSMB10
 proteasome (prosome, macropain) subunit, beta type, 10
chr3_+_8543533 0.53 ENST00000454244.1
 LMCD1
 LIM and cysteine-rich domains 1
chr9_+_18474204 0.53 ENST00000276935.6
 ADAMTSL1
 ADAMTS-like 1
chrX_-_63005405 0.50 ENST00000374878.1
ENST00000437457.2
 ARHGEF9
 Cdc42 guanine nucleotide exchange factor (GEF) 9
chrX_-_118826784 0.45 ENST00000394616.4
 SEPT6
 septin 6
chr4_+_142557717 0.45 ENST00000320650.4
ENST00000296545.7
 IL15
 interleukin 15
chrX_-_118827113 0.44 ENST00000394617.2
 SEPT6
 septin 6
chr5_+_112227311 0.43 ENST00000391338.1
 ZRSR1
 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr4_+_142557771 0.42 ENST00000514653.1
 IL15
 interleukin 15
chr8_-_116681221 0.41 ENST00000395715.3
 TRPS1
 trichorhinophalangeal syndrome I
chr11_-_96076334 0.39 ENST00000524717.1
 MAML2
 mastermind-like 2 (Drosophila)
chr3_-_114343039 0.38 ENST00000481632.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr5_-_93447333 0.38 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
 FAM172A
 family with sequence similarity 172, member A
chr4_+_142558078 0.38 ENST00000529613.1
 IL15
 interleukin 15
chr10_-_50747064 0.38 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
 ERCC6
PGBD3
ERCC6-PGBD3
 excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr1_-_182361327 0.36 ENST00000331872.6
ENST00000311223.5
 GLUL
 glutamate-ammonia ligase
chrX_+_10124977 0.36 ENST00000380833.4
 CLCN4
 chloride channel, voltage-sensitive 4
chr2_+_231191875 0.36 ENST00000444636.1
ENST00000415673.2
ENST00000243810.6
ENST00000396563.4
 SP140L
 SP140 nuclear body protein-like
chr19_+_49977818 0.34 ENST00000594009.1
ENST00000595510.1
 FLT3LG
 fms-related tyrosine kinase 3 ligand
chr14_+_24605389 0.30 ENST00000382708.3
ENST00000561435.1
 PSME1
 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_-_182360918 0.30 ENST00000339526.4
 GLUL
 glutamate-ammonia ligase
chr7_+_95401877 0.29 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
chr12_+_94542459 0.29 ENST00000258526.4
 PLXNC1
 plexin C1
chr6_-_112575687 0.29 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
 LAMA4
 laminin, alpha 4
chr12_+_94656297 0.28 ENST00000545312.1
 PLXNC1
 plexin C1
chr5_+_49962495 0.27 ENST00000515175.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr2_+_175260514 0.27 ENST00000424069.1
ENST00000427038.1
 SCRN3
 secernin 3
chr6_-_137113604 0.26 ENST00000359015.4
 MAP3K5
 mitogen-activated protein kinase kinase kinase 5
chr7_+_7811992 0.26 ENST00000406829.1
 RPA3-AS1
 RPA3 antisense RNA 1
chr16_+_50775971 0.26 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
 CYLD
 cylindromatosis (turban tumor syndrome)
chr2_+_175260451 0.25 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
 SCRN3
 secernin 3
chr8_-_116680833 0.25 ENST00000220888.5
 TRPS1
 trichorhinophalangeal syndrome I
chr12_+_51318513 0.25 ENST00000332160.4
 METTL7A
 methyltransferase like 7A
chr17_+_46908350 0.23 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
 CALCOCO2
 calcium binding and coiled-coil domain 2
chr16_+_50775948 0.23 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
 CYLD
 cylindromatosis (turban tumor syndrome)
chr12_-_54653313 0.23 ENST00000550411.1
ENST00000439541.2
 CBX5
 chromobox homolog 5
chr21_+_17909594 0.23 ENST00000441820.1
ENST00000602280.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr2_+_166150541 0.23 ENST00000283256.6
 SCN2A
 sodium channel, voltage-gated, type II, alpha subunit
chr2_-_231084617 0.22 ENST00000409815.2
 SP110
 SP110 nuclear body protein
chr1_+_110453109 0.22 ENST00000525659.1
 CSF1
 colony stimulating factor 1 (macrophage)
chr4_+_186990298 0.22 ENST00000296795.3
ENST00000513189.1
 TLR3
 toll-like receptor 3
chr22_-_36635684 0.22 ENST00000358502.5
 APOL2
 apolipoprotein L, 2
chr8_-_29120580 0.20 ENST00000524189.1
 KIF13B
 kinesin family member 13B
chr3_+_185046676 0.20 ENST00000428617.1
ENST00000443863.1
 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
chr20_+_388791 0.20 ENST00000441733.1
ENST00000353660.3
 RBCK1
 RanBP-type and C3HC4-type zinc finger containing 1
chr4_-_54457783 0.20 ENST00000263925.7
ENST00000512247.1
 LNX1
 ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr20_-_57089934 0.20 ENST00000439429.1
ENST00000371149.3
 APCDD1L
 adenomatosis polyposis coli down-regulated 1-like
chr13_+_31309645 0.19 ENST00000380490.3
 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
chr6_+_31540056 0.19 ENST00000418386.2
 LTA
 lymphotoxin alpha
chr11_+_71710648 0.19 ENST00000260049.5
 IL18BP
 interleukin 18 binding protein
chr14_+_24605361 0.19 ENST00000206451.6
ENST00000559123.1
 PSME1
 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr9_+_137533615 0.19 ENST00000371817.3
 COL5A1
 collagen, type V, alpha 1
chr6_-_154831779 0.19 ENST00000607772.1
 CNKSR3
 CNKSR family member 3
chr7_+_134464376 0.18 ENST00000454108.1
ENST00000361675.2
 CALD1
 caldesmon 1
chr22_-_36556821 0.18 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
 APOL3
 apolipoprotein L, 3
chr14_-_24615805 0.18 ENST00000560410.1
 PSME2
 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr20_+_30946106 0.18 ENST00000375687.4
ENST00000542461.1
 ASXL1
 additional sex combs like 1 (Drosophila)
chr6_+_32821924 0.17 ENST00000374859.2
ENST00000453265.2
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr11_+_71710973 0.17 ENST00000393707.4
 IL18BP
 interleukin 18 binding protein
chr8_+_134203273 0.17 ENST00000250160.6
 WISP1
 WNT1 inducible signaling pathway protein 1
chr10_-_82049424 0.17 ENST00000372213.3
 MAT1A
 methionine adenosyltransferase I, alpha
chr14_-_24615523 0.17 ENST00000559056.1
 PSME2
 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr13_+_24144509 0.17 ENST00000248484.4
 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
chr17_+_6659153 0.17 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
 XAF1
 XIAP associated factor 1
chr6_+_32811885 0.16 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
 TAPSAR1
PSMB9
 TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr13_+_108921977 0.16 ENST00000430559.1
ENST00000375887.4
 TNFSF13B
 tumor necrosis factor (ligand) superfamily, member 13b
chr2_+_231280954 0.16 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
 SP100
 SP100 nuclear antigen
chr17_-_26694979 0.16 ENST00000438614.1
 VTN
 vitronectin
chr22_-_31688381 0.16 ENST00000487265.2
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr1_-_205325850 0.16 ENST00000537168.1
 KLHDC8A
 kelch domain containing 8A
chr5_-_149380698 0.15 ENST00000296736.3
 TIGD6
 tigger transposable element derived 6
chr6_+_32811861 0.15 ENST00000453426.1
 TAPSAR1
 TAP1 and PSMB8 antisense RNA 1
chr17_-_26695013 0.15 ENST00000555059.2
 CTB-96E2.2
 Homeobox protein SEBOX
chr8_-_54436491 0.15 ENST00000426023.1
 RP11-400K9.4
 RP11-400K9.4
chr14_-_69263043 0.14 ENST00000408913.2
 ZFP36L1
 ZFP36 ring finger protein-like 1
chr6_+_57182400 0.14 ENST00000607273.1
 PRIM2
 primase, DNA, polypeptide 2 (58kDa)
chr1_+_110453462 0.14 ENST00000488198.1
 CSF1
 colony stimulating factor 1 (macrophage)
chr16_-_31085514 0.14 ENST00000300849.4
 ZNF668
 zinc finger protein 668
chr12_+_6561190 0.14 ENST00000544021.1
ENST00000266556.7
 TAPBPL
 TAP binding protein-like
chr10_-_35104185 0.13 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
 PARD3
 par-3 family cell polarity regulator
chr7_+_134464414 0.13 ENST00000361901.2
 CALD1
 caldesmon 1
chr3_+_119013185 0.13 ENST00000264245.4
 ARHGAP31
 Rho GTPase activating protein 31
chr11_+_71709938 0.13 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
 IL18BP
 interleukin 18 binding protein
chr15_-_37392086 0.13 ENST00000561208.1
 MEIS2
 Meis homeobox 2
chr9_+_18474163 0.12 ENST00000380566.4
 ADAMTSL1
 ADAMTS-like 1
chr2_-_231084820 0.12 ENST00000258382.5
ENST00000338556.3
 SP110
 SP110 nuclear body protein
chr2_+_69240302 0.12 ENST00000303714.4
 ANTXR1
 anthrax toxin receptor 1
chr6_-_105584560 0.12 ENST00000336775.5
 BVES
 blood vessel epicardial substance
chr11_+_46402297 0.12 ENST00000405308.2
 MDK
 midkine (neurite growth-promoting factor 2)
chr13_+_24144796 0.11 ENST00000403372.2
 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
chr18_+_18943554 0.11 ENST00000580732.2
 GREB1L
 growth regulation by estrogen in breast cancer-like
chr6_-_32811771 0.10 ENST00000395339.3
ENST00000374882.3
 PSMB8
 proteasome (prosome, macropain) subunit, beta type, 8
chr6_-_112575758 0.10 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
 LAMA4
 laminin, alpha 4
chr2_+_239756671 0.09 ENST00000448943.2
 TWIST2
 twist family bHLH transcription factor 2
chr10_-_112678692 0.09 ENST00000605742.1
 BBIP1
 BBSome interacting protein 1
chr2_-_231084659 0.09 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
 SP110
 SP110 nuclear body protein
chr12_-_95941987 0.09 ENST00000537435.2
 USP44
 ubiquitin specific peptidase 44
chr15_-_56209306 0.09 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr6_-_112575838 0.09 ENST00000455073.1
 LAMA4
 laminin, alpha 4
chr8_+_77318769 0.09 ENST00000518732.1
 RP11-706J10.1
 long intergenic non-protein coding RNA 1111
chr6_-_28220002 0.09 ENST00000377294.2
 ZKSCAN4
 zinc finger with KRAB and SCAN domains 4
chr11_+_46402744 0.08 ENST00000533952.1
 MDK
 midkine (neurite growth-promoting factor 2)
chr19_-_6670128 0.08 ENST00000245912.3
 TNFSF14
 tumor necrosis factor (ligand) superfamily, member 14
chr16_+_50776021 0.07 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
 CYLD
 cylindromatosis (turban tumor syndrome)
chr11_+_46402583 0.07 ENST00000359803.3
 MDK
 midkine (neurite growth-promoting factor 2)
chr22_+_41697520 0.07 ENST00000352645.4
 ZC3H7B
 zinc finger CCCH-type containing 7B
chr21_-_35899113 0.07 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
 RCAN1
 regulator of calcineurin 1
chr22_-_31688431 0.07 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr15_+_71185148 0.07 ENST00000443425.2
ENST00000560755.1
 LRRC49
 leucine rich repeat containing 49
chr2_-_70475586 0.07 ENST00000416149.2
 TIA1
 TIA1 cytotoxic granule-associated RNA binding protein
chr5_+_76506706 0.07 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
 PDE8B
 phosphodiesterase 8B
chr2_-_175260368 0.06 ENST00000342016.3
ENST00000362053.5
 CIR1
 corepressor interacting with RBPJ, 1
chr20_+_13976015 0.06 ENST00000217246.4
 MACROD2
 MACRO domain containing 2
chrX_-_119694538 0.06 ENST00000371322.5
 CUL4B
 cullin 4B
chr8_+_96145974 0.05 ENST00000315367.3
 PLEKHF2
 pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr2_+_231280908 0.05 ENST00000427101.2
ENST00000432979.1
 SP100
 SP100 nuclear antigen
chr6_-_112575912 0.05 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
 LAMA4
 laminin, alpha 4
chr1_+_28099683 0.05 ENST00000373943.4
 STX12
 syntaxin 12
chr10_+_22610124 0.04 ENST00000376663.3
 BMI1
 BMI1 polycomb ring finger oncogene
chr7_+_128355439 0.04 ENST00000315184.5
 FAM71F1
 family with sequence similarity 71, member F1
chr4_-_74088800 0.04 ENST00000509867.2
 ANKRD17
 ankyrin repeat domain 17
chr15_+_71184931 0.04 ENST00000560369.1
ENST00000260382.5
 LRRC49
 leucine rich repeat containing 49
chr12_-_118498958 0.04 ENST00000315436.3
 WSB2
 WD repeat and SOCS box containing 2
chr1_+_151372010 0.04 ENST00000290541.6
 PSMB4
 proteasome (prosome, macropain) subunit, beta type, 4
chr22_-_30642782 0.04 ENST00000249075.3
 LIF
 leukemia inhibitory factor
chr16_+_30675654 0.04 ENST00000287468.5
ENST00000395073.2
 FBRS
 fibrosin
chr15_+_78832747 0.04 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
 PSMA4
 proteasome (prosome, macropain) subunit, alpha type, 4
chr11_+_46402482 0.04 ENST00000441869.1
 MDK
 midkine (neurite growth-promoting factor 2)
chr1_+_181003067 0.04 ENST00000434571.2
ENST00000367579.3
ENST00000282990.6
ENST00000367580.5
 MR1
 major histocompatibility complex, class I-related
chr3_-_149375783 0.04 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
 WWTR1
 WW domain containing transcription regulator 1
chr6_-_33282024 0.03 ENST00000475304.1
ENST00000489157.1
 TAPBP
 TAP binding protein (tapasin)
chr5_-_96143796 0.03 ENST00000296754.3
 ERAP1
 endoplasmic reticulum aminopeptidase 1
chr12_-_52800139 0.03 ENST00000257974.2
 KRT82
 keratin 82
chr10_-_21661870 0.03 ENST00000433460.1
 RP11-275N1.1
 RP11-275N1.1
chr2_+_69240415 0.03 ENST00000409829.3
 ANTXR1
 anthrax toxin receptor 1
chrX_-_133930285 0.03 ENST00000486347.1
ENST00000343004.5
 FAM122B
 family with sequence similarity 122B
chr1_+_110453203 0.03 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
 CSF1
 colony stimulating factor 1 (macrophage)
chr19_+_24009879 0.03 ENST00000354585.4
 RPSAP58
 ribosomal protein SA pseudogene 58
chr6_+_118869452 0.03 ENST00000357525.5
 PLN
 phospholamban
chr6_+_26156551 0.03 ENST00000304218.3
 HIST1H1E
 histone cluster 1, H1e
chr8_-_56986768 0.02 ENST00000523936.1
 RPS20
 ribosomal protein S20
chr5_+_17444119 0.02 ENST00000503267.1
ENST00000504998.1
 RP11-321E2.4
 RP11-321E2.4
chr6_+_146348810 0.02 ENST00000492807.2
 GRM1
 glutamate receptor, metabotropic 1
chr4_-_100140331 0.02 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
 ADH6
 alcohol dehydrogenase 6 (class V)
chr2_-_202508169 0.02 ENST00000409883.2
 TMEM237
 transmembrane protein 237
chr3_-_44552094 0.02 ENST00000436261.1
 ZNF852
 zinc finger protein 852
chr6_+_108616243 0.02 ENST00000421954.1
 LACE1
 lactation elevated 1
chr17_+_3379284 0.02 ENST00000263080.2
 ASPA
 aspartoacylase
chr12_-_50561075 0.01 ENST00000422340.2
ENST00000317551.6
 CERS5
 ceramide synthase 5
chr9_-_69229650 0.01 ENST00000416428.1
 CBWD6
 COBW domain containing 6
chr14_-_23479331 0.01 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
 C14orf93
 chromosome 14 open reading frame 93
chr1_+_199996702 0.01 ENST00000367362.3
 NR5A2
 nuclear receptor subfamily 5, group A, member 2
chr11_-_40315640 0.01 ENST00000278198.2
 LRRC4C
 leucine rich repeat containing 4C
chr6_-_33281979 0.01 ENST00000426633.2
ENST00000467025.1
 TAPBP
 TAP binding protein (tapasin)
chr20_+_388679 0.01 ENST00000356286.5
ENST00000475269.1
 RBCK1
 RanBP-type and C3HC4-type zinc finger containing 1
chr6_-_32806483 0.01 ENST00000374899.4
 TAP2
 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr18_-_47017956 0.01 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
 RPL17-C18orf32
RPL17
 RPL17-C18orf32 readthrough
ribosomal protein L17
chr8_-_9009079 0.00 ENST00000519699.1
 PPP1R3B
 protein phosphatase 1, regulatory subunit 3B
chr8_+_134203303 0.00 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
 WISP1
 WNT1 inducible signaling pathway protein 1
chr10_+_18429671 0.00 ENST00000282343.8
 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
chr16_+_31085714 0.00 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
 ZNF646
 zinc finger protein 646
chr6_-_132910877 0.00 ENST00000258034.2
 TAAR5
 trace amine associated receptor 5
chr4_+_152020715 0.00 ENST00000274065.4
 RPS3A
 ribosomal protein S3A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0045062 extrathymic T cell selection(GO:0045062)
0.3 1.6 GO:0008218 bioluminescence(GO:0008218)
0.2 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 2.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.9 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0034344 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.6 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.5 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.9 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.8 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0089701 U2AF(GO:0089701)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.7 GO:0097386 glial cell projection(GO:0097386)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.6 GO:0097542 ciliary tip(GO:0097542)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.5 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 1.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling