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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for RFX3_RFX2

Z-value: 1.23

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Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
RFX3
ENSG00000080298.11 RFX3
RFX2
ENSG00000087903.8 RFX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg19_v2_chr19_-_6110474_6110551-0.285.0e-01Click!
RFX3hg19_v2_chr9_-_3525968_35260160.216.2e-01Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_183605200 1.63 ENST00000304685.4
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr5_+_92919043 1.58 ENST00000327111.3
 NR2F1
 nuclear receptor subfamily 2, group F, member 1
chr5_-_179780312 1.27 ENST00000253778.8
 GFPT2
 glutamine-fructose-6-phosphate transaminase 2
chr11_+_133938820 1.24 ENST00000299106.4
ENST00000529443.2
 JAM3
 junctional adhesion molecule 3
chr7_+_100797726 1.16 ENST00000429457.1
 AP1S1
 adaptor-related protein complex 1, sigma 1 subunit
chr11_+_133938955 1.14 ENST00000534549.1
ENST00000441717.3
 JAM3
 junctional adhesion molecule 3
chr19_+_35630926 1.09 ENST00000588081.1
ENST00000589121.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chr16_+_8806800 1.07 ENST00000561870.1
ENST00000396600.2
 ABAT
 4-aminobutyrate aminotransferase
chr12_-_58329819 1.06 ENST00000551421.1
 RP11-620J15.3
 RP11-620J15.3
chr8_+_120428546 1.05 ENST00000259526.3
 NOV
 nephroblastoma overexpressed
chr14_+_105941118 1.04 ENST00000550577.1
ENST00000538259.2
 CRIP2
 cysteine-rich protein 2
chr10_+_104178946 1.01 ENST00000432590.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chr22_-_43485381 0.98 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
 TTLL1
 tubulin tyrosine ligase-like family, member 1
chr12_+_4671352 0.97 ENST00000542744.1
 DYRK4
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr1_-_232598163 0.97 ENST00000308942.4
 SIPA1L2
 signal-induced proliferation-associated 1 like 2
chr2_+_242811874 0.96 ENST00000343216.3
 CXXC11
 CXXC finger protein 11
chr15_+_43803143 0.96 ENST00000382031.1
 MAP1A
 microtubule-associated protein 1A
chr19_+_35630022 0.95 ENST00000589209.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chr1_+_245133278 0.95 ENST00000366522.2
 EFCAB2
 EF-hand calcium binding domain 2
chr2_-_175870085 0.93 ENST00000409156.3
 CHN1
 chimerin 1
chr20_+_43160458 0.93 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
 PKIG
 protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr20_+_43160409 0.91 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
 PKIG
 protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr12_-_63328817 0.91 ENST00000228705.6
 PPM1H
 protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr2_-_175869936 0.89 ENST00000409900.3
 CHN1
 chimerin 1
chr7_+_150065278 0.88 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
 REPIN1
 replication initiator 1
chr1_-_109656439 0.88 ENST00000369949.4
 C1orf194
 chromosome 1 open reading frame 194
chr6_+_112408768 0.86 ENST00000368656.2
ENST00000604268.1
 FAM229B
 family with sequence similarity 229, member B
chr13_-_44361025 0.79 ENST00000261488.6
 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
chr14_+_100259666 0.78 ENST00000262233.6
ENST00000334192.4
 EML1
 echinoderm microtubule associated protein like 1
chr14_+_76044934 0.77 ENST00000238667.4
 FLVCR2
 feline leukemia virus subgroup C cellular receptor family, member 2
chr3_-_58563094 0.76 ENST00000464064.1
 FAM107A
 family with sequence similarity 107, member A
chrX_+_85969626 0.76 ENST00000484479.1
 DACH2
 dachshund homolog 2 (Drosophila)
chr3_-_197676740 0.75 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
 IQCG
 IQ motif containing G
chr2_+_74648848 0.75 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
 WDR54
 WD repeat domain 54
chr16_+_29823427 0.74 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
 PRRT2
 proline-rich transmembrane protein 2
chr12_-_58329888 0.74 ENST00000546580.1
 RP11-620J15.3
 RP11-620J15.3
chr16_+_29823552 0.73 ENST00000300797.6
 PRRT2
 proline-rich transmembrane protein 2
chr19_+_35630628 0.73 ENST00000588715.1
ENST00000588607.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chr1_+_42928945 0.73 ENST00000428554.2
 CCDC30
 coiled-coil domain containing 30
chr17_-_64187973 0.72 ENST00000583358.1
ENST00000392769.2
 CEP112
 centrosomal protein 112kDa
chr1_-_48937838 0.72 ENST00000371847.3
 SPATA6
 spermatogenesis associated 6
chr5_+_148521381 0.72 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr1_+_38022513 0.72 ENST00000296218.7
 DNALI1
 dynein, axonemal, light intermediate chain 1
chr17_-_64188177 0.70 ENST00000535342.2
 CEP112
 centrosomal protein 112kDa
chr22_-_31063782 0.70 ENST00000404885.1
ENST00000403268.1
ENST00000407308.1
ENST00000342474.4
ENST00000334679.3
 DUSP18
 dual specificity phosphatase 18
chr7_+_150065879 0.69 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
 REPIN1
ZNF775
 replication initiator 1
zinc finger protein 775
chr6_+_30524663 0.68 ENST00000376560.3
 PRR3
 proline rich 3
chr14_+_74486043 0.67 ENST00000464394.1
ENST00000394009.3
 CCDC176
 coiled-coil domain containing 176
chr2_+_220144052 0.66 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr2_-_203735976 0.65 ENST00000435143.1
 ICA1L
 islet cell autoantigen 1,69kDa-like
chr15_+_55700741 0.65 ENST00000569691.1
 C15orf65
 chromosome 15 open reading frame 65
chr12_-_110486348 0.64 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
 C12orf76
 chromosome 12 open reading frame 76
chr2_-_130902567 0.64 ENST00000457413.1
ENST00000392984.3
ENST00000409128.1
ENST00000441670.1
ENST00000409943.3
ENST00000409234.3
ENST00000310463.6
 CCDC74B
 coiled-coil domain containing 74B
chr3_-_196439065 0.64 ENST00000399942.4
ENST00000409690.3
 CEP19
 centrosomal protein 19kDa
chrX_+_135251835 0.62 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr11_-_6426635 0.62 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
 APBB1
 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_+_10527449 0.62 ENST00000592685.1
ENST00000380702.2
 PDE4A
 phosphodiesterase 4A, cAMP-specific
chr1_-_48937821 0.61 ENST00000396199.3
 SPATA6
 spermatogenesis associated 6
chr8_+_16884740 0.61 ENST00000318063.5
 MICU3
 mitochondrial calcium uptake family, member 3
chrX_-_71351678 0.61 ENST00000609883.1
ENST00000545866.1
 RGAG4
 retrotransposon gag domain containing 4
chr12_+_51818749 0.61 ENST00000514353.3
 SLC4A8
 solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr8_+_13424352 0.61 ENST00000297324.4
 C8orf48
 chromosome 8 open reading frame 48
chr7_+_100797678 0.61 ENST00000337619.5
 AP1S1
 adaptor-related protein complex 1, sigma 1 subunit
chr1_+_161068179 0.61 ENST00000368011.4
ENST00000392192.2
 KLHDC9
 kelch domain containing 9
chr6_+_30525051 0.61 ENST00000376557.3
 PRR3
 proline rich 3
chr2_+_132285406 0.60 ENST00000295171.6
ENST00000409856.3
 CCDC74A
 coiled-coil domain containing 74A
chr12_+_48577366 0.60 ENST00000316554.3
 C12orf68
 chromosome 12 open reading frame 68
chr12_+_51818555 0.60 ENST00000453097.2
 SLC4A8
 solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr12_+_51818586 0.60 ENST00000394856.1
 SLC4A8
 solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr14_+_24025194 0.59 ENST00000404535.3
ENST00000288014.6
 THTPA
 thiamine triphosphatase
chr19_+_35630344 0.59 ENST00000455515.2
 FXYD1
 FXYD domain containing ion transport regulator 1
chr14_-_74181106 0.56 ENST00000316836.3
 PNMA1
 paraneoplastic Ma antigen 1
chr10_+_124030819 0.55 ENST00000260723.4
ENST00000368994.2
 BTBD16
 BTB (POZ) domain containing 16
chr19_-_50529193 0.54 ENST00000596445.1
ENST00000599538.1
 VRK3
 vaccinia related kinase 3
chr1_-_48937682 0.54 ENST00000371843.3
 SPATA6
 spermatogenesis associated 6
chr17_-_26662440 0.54 ENST00000578122.1
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr22_+_27053422 0.53 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
 MIAT
 myocardial infarction associated transcript (non-protein coding)
chr1_+_38022572 0.53 ENST00000541606.1
 DNALI1
 dynein, axonemal, light intermediate chain 1
chr12_-_131323719 0.53 ENST00000392373.2
 STX2
 syntaxin 2
chr3_+_48507210 0.53 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
 TREX1
 three prime repair exonuclease 1
chr22_+_27053190 0.52 ENST00000439738.1
ENST00000422403.1
ENST00000436238.1
ENST00000425476.1
ENST00000455640.1
ENST00000451141.1
ENST00000452429.1
ENST00000423278.1
 MIAT
 myocardial infarction associated transcript (non-protein coding)
chrX_+_103173457 0.52 ENST00000419165.1
 TMSB15B
 thymosin beta 15B
chr7_-_100965011 0.51 ENST00000498704.2
ENST00000517481.1
ENST00000437644.2
ENST00000315322.4
 RABL5
 RAB, member RAS oncogene family-like 5
chr3_-_196045127 0.51 ENST00000325318.5
 TCTEX1D2
 Tctex1 domain containing 2
chr11_-_66104237 0.51 ENST00000530056.1
 RIN1
 Ras and Rab interactor 1
chr7_+_102073966 0.50 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
 ORAI2
 ORAI calcium release-activated calcium modulator 2
chr17_-_26662464 0.50 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr3_+_48507621 0.50 ENST00000456089.1
 TREX1
 three prime repair exonuclease 1
chr17_-_16472483 0.50 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
 ZNF287
 zinc finger protein 287
chrX_+_135251783 0.50 ENST00000394153.2
 FHL1
 four and a half LIM domains 1
chr12_-_48500085 0.49 ENST00000549518.1
 SENP1
 SUMO1/sentrin specific peptidase 1
chr5_+_154237778 0.49 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr6_+_52285131 0.49 ENST00000433625.2
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr11_+_111807863 0.48 ENST00000440460.2
 DIXDC1
 DIX domain containing 1
chr5_-_133702761 0.47 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
 CDKL3
 cyclin-dependent kinase-like 3
chr16_+_3550924 0.47 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
 CLUAP1
 clusterin associated protein 1
chr19_-_46974664 0.47 ENST00000438932.2
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr19_-_46974741 0.47 ENST00000313683.10
ENST00000602246.1
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr19_+_3572758 0.47 ENST00000416526.1
 HMG20B
 high mobility group 20B
chr9_+_35829208 0.47 ENST00000439587.2
ENST00000377991.4
 TMEM8B
 transmembrane protein 8B
chr17_+_66508537 0.46 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chrX_+_135252050 0.45 ENST00000449474.1
ENST00000345434.3
 FHL1
 four and a half LIM domains 1
chr17_+_66508154 0.44 ENST00000358598.2
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_-_186733363 0.44 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2
 sorbin and SH3 domain containing 2
chr12_+_56511943 0.44 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
 ZC3H10
ESYT1
 zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr3_-_107941209 0.44 ENST00000492106.1
 IFT57
 intraflagellar transport 57 homolog (Chlamydomonas)
chr9_-_131418944 0.44 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
 WDR34
 WD repeat domain 34
chr22_+_37447771 0.44 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
 KCTD17
 potassium channel tetramerization domain containing 17
chr1_-_36916066 0.44 ENST00000315643.9
 OSCP1
 organic solute carrier partner 1
chr12_+_53689309 0.43 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
 PFDN5
 prefoldin subunit 5
chr6_-_41703296 0.43 ENST00000373033.1
 TFEB
 transcription factor EB
chr22_+_39052632 0.43 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
 CBY1
 chibby homolog 1 (Drosophila)
chr19_-_14048804 0.43 ENST00000254320.3
ENST00000586075.1
 PODNL1
 podocan-like 1
chr19_-_6393216 0.42 ENST00000595047.1
 GTF2F1
 general transcription factor IIF, polypeptide 1, 74kDa
chr1_-_118727781 0.42 ENST00000336338.5
 SPAG17
 sperm associated antigen 17
chr6_-_41703952 0.42 ENST00000358871.2
ENST00000403298.4
 TFEB
 transcription factor EB
chr6_+_52285046 0.41 ENST00000371068.5
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr8_+_38243821 0.41 ENST00000519476.2
 LETM2
 leucine zipper-EF-hand containing transmembrane protein 2
chr12_+_7014064 0.41 ENST00000443597.2
 LRRC23
 leucine rich repeat containing 23
chr16_+_57279248 0.41 ENST00000562023.1
ENST00000563234.1
 ARL2BP
 ADP-ribosylation factor-like 2 binding protein
chr3_-_16306432 0.41 ENST00000383775.4
ENST00000488423.1
 DPH3
 diphthamide biosynthesis 3
chr3_+_9851632 0.41 ENST00000426895.4
 TTLL3
 tubulin tyrosine ligase-like family, member 3
chr17_+_260097 0.41 ENST00000360127.6
ENST00000571106.1
ENST00000491373.1
 C17orf97
 chromosome 17 open reading frame 97
chr19_+_17413663 0.40 ENST00000594999.1
 MRPL34
 mitochondrial ribosomal protein L34
chr11_+_46958248 0.40 ENST00000536126.1
ENST00000278460.7
ENST00000378618.2
ENST00000395460.2
ENST00000378615.3
ENST00000543718.1
 C11orf49
 chromosome 11 open reading frame 49
chr7_-_44229022 0.40 ENST00000403799.3
 GCK
 glucokinase (hexokinase 4)
chr2_+_55746746 0.40 ENST00000406691.3
ENST00000349456.4
ENST00000407816.3
ENST00000403007.3
 CCDC104
 coiled-coil domain containing 104
chr17_+_6544078 0.40 ENST00000250101.5
 TXNDC17
 thioredoxin domain containing 17
chr14_+_24025462 0.39 ENST00000556015.1
ENST00000554970.1
ENST00000554789.1
 THTPA
 thiamine triphosphatase
chr15_-_55700457 0.39 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
 CCPG1
 cell cycle progression 1
chr7_-_1177874 0.39 ENST00000397098.3
ENST00000357429.6
ENST00000397100.2
ENST00000491163.1
 C7orf50
 chromosome 7 open reading frame 50
chr2_+_39103103 0.39 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
 MORN2
 MORN repeat containing 2
chr12_+_9067123 0.38 ENST00000543824.1
 PHC1
 polyhomeotic homolog 1 (Drosophila)
chr5_-_81046904 0.38 ENST00000515395.1
 SSBP2
 single-stranded DNA binding protein 2
chr11_-_66103932 0.38 ENST00000311320.4
 RIN1
 Ras and Rab interactor 1
chr11_+_120894781 0.38 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
 TBCEL
 tubulin folding cofactor E-like
chr15_-_65282232 0.37 ENST00000416889.2
 SPG21
 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr12_+_7013897 0.37 ENST00000007969.8
ENST00000323702.5
 LRRC23
 leucine rich repeat containing 23
chr12_-_110011288 0.37 ENST00000540016.1
ENST00000266839.5
 MMAB
 methylmalonic aciduria (cobalamin deficiency) cblB type
chr11_+_66360665 0.36 ENST00000310190.4
 CCS
 copper chaperone for superoxide dismutase
chr21_+_40817749 0.36 ENST00000380637.3
ENST00000380634.1
ENST00000458295.1
ENST00000440288.2
ENST00000380631.1
 SH3BGR
 SH3 domain binding glutamic acid-rich protein
chr17_-_19266045 0.36 ENST00000395616.3
 B9D1
 B9 protein domain 1
chr2_+_48667983 0.36 ENST00000449090.2
 PPP1R21
 protein phosphatase 1, regulatory subunit 21
chr19_-_14049184 0.36 ENST00000339560.5
 PODNL1
 podocan-like 1
chr15_-_65281775 0.36 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
 SPG21
 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr15_-_65282274 0.36 ENST00000204566.2
 SPG21
 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr3_-_149688896 0.36 ENST00000239940.7
 PFN2
 profilin 2
chr16_+_57279004 0.36 ENST00000219204.3
 ARL2BP
 ADP-ribosylation factor-like 2 binding protein
chr5_-_159797627 0.35 ENST00000393975.3
 C1QTNF2
 C1q and tumor necrosis factor related protein 2
chr2_+_55746722 0.35 ENST00000339012.3
 CCDC104
 coiled-coil domain containing 104
chr5_-_81046841 0.35 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
 SSBP2
 single-stranded DNA binding protein 2
chr3_-_50383096 0.35 ENST00000442887.1
ENST00000360165.3
 ZMYND10
 zinc finger, MYND-type containing 10
chrX_-_131623874 0.34 ENST00000436215.1
 MBNL3
 muscleblind-like splicing regulator 3
chr15_-_43802769 0.34 ENST00000263801.3
 TP53BP1
 tumor protein p53 binding protein 1
chr11_-_66103867 0.34 ENST00000424433.2
 RIN1
 Ras and Rab interactor 1
chr1_-_36916011 0.34 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
 OSCP1
 organic solute carrier partner 1
chr11_-_67271723 0.33 ENST00000533391.1
ENST00000534749.1
ENST00000532703.1
 PITPNM1
 phosphatidylinositol transfer protein, membrane-associated 1
chr17_-_15244894 0.33 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
 TEKT3
 tektin 3
chr13_-_114843416 0.33 ENST00000389544.4
 RASA3
 RAS p21 protein activator 3
chr1_-_114301503 0.33 ENST00000447664.2
 PHTF1
 putative homeodomain transcription factor 1
chr14_-_20774092 0.33 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
 TTC5
 tetratricopeptide repeat domain 5
chr6_-_27440460 0.33 ENST00000377419.1
 ZNF184
 zinc finger protein 184
chr9_+_100069933 0.33 ENST00000529487.1
 CCDC180
 coiled-coil domain containing 180
chr6_+_35227449 0.32 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
 ZNF76
 zinc finger protein 76
chr17_-_76899275 0.32 ENST00000322630.2
ENST00000586713.1
 DDC8
 Protein DDC8 homolog
chr8_-_101118185 0.32 ENST00000523437.1
 RGS22
 regulator of G-protein signaling 22
chr12_-_54653313 0.32 ENST00000550411.1
ENST00000439541.2
 CBX5
 chromobox homolog 5
chr1_+_3541543 0.32 ENST00000378344.2
ENST00000344579.5
 TPRG1L
 tumor protein p63 regulated 1-like
chr3_-_49055991 0.32 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
 DALRD3
 DALR anticodon binding domain containing 3
chr17_-_72358001 0.32 ENST00000375366.3
 BTBD17
 BTB (POZ) domain containing 17
chr1_+_161129254 0.32 ENST00000368002.3
ENST00000289865.8
ENST00000479344.1
ENST00000368001.1
 USP21
 ubiquitin specific peptidase 21
chr1_+_33546714 0.32 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
 ADC
 arginine decarboxylase
chr3_-_107941230 0.31 ENST00000264538.3
 IFT57
 intraflagellar transport 57 homolog (Chlamydomonas)
chr1_-_167905225 0.31 ENST00000367846.4
 MPC2
 mitochondrial pyruvate carrier 2
chr6_-_27440837 0.31 ENST00000211936.6
 ZNF184
 zinc finger protein 184
chr20_-_48532046 0.31 ENST00000543716.1
 SPATA2
 spermatogenesis associated 2
chr17_+_78389247 0.31 ENST00000520136.2
ENST00000520284.1
ENST00000517795.1
ENST00000523228.1
ENST00000523828.1
ENST00000522200.1
ENST00000521565.1
ENST00000518907.1
ENST00000518644.1
ENST00000518901.1
 ENDOV
 endonuclease V
chr17_-_53046058 0.31 ENST00000571584.1
ENST00000299335.3
 COX11
 cytochrome c oxidase assembly homolog 11 (yeast)
chr5_-_81046922 0.31 ENST00000514493.1
ENST00000320672.4
 SSBP2
 single-stranded DNA binding protein 2
chr3_+_9851904 0.30 ENST00000547186.1
ENST00000397241.1
ENST00000426827.1
 TTLL3
 tubulin tyrosine ligase-like family, member 3
chrX_+_48455866 0.30 ENST00000376729.5
ENST00000218056.5
 WDR13
 WD repeat domain 13
chr7_+_138916231 0.30 ENST00000473989.3
ENST00000288561.8
 UBN2
 ubinuclein 2
chr19_+_18263928 0.30 ENST00000222254.8
 PIK3R2
 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr6_-_43478239 0.30 ENST00000372441.1
 LRRC73
 leucine rich repeat containing 73
chr2_+_237994519 0.30 ENST00000392008.2
ENST00000409334.1
ENST00000409629.1
 COPS8
 COP9 signalosome subunit 8
chr19_-_50528584 0.30 ENST00000594092.1
ENST00000443401.2
ENST00000594948.1
ENST00000377011.2
ENST00000593919.1
ENST00000601324.1
ENST00000316763.3
ENST00000601341.1
ENST00000600259.1
 VRK3
 vaccinia related kinase 3
chr12_-_131323754 0.30 ENST00000261653.6
 STX2
 syntaxin 2
chr19_+_50879705 0.30 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
 NR1H2
 nuclear receptor subfamily 1, group H, member 2
chr11_-_124981475 0.29 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
 TMEM218
 transmembrane protein 218
chr22_-_44894178 0.29 ENST00000341255.3
 LDOC1L
 leucine zipper, down-regulated in cancer 1-like
chr11_+_61447845 0.29 ENST00000257215.5
 DAGLA
 diacylglycerol lipase, alpha
chr19_-_4535233 0.29 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
 PLIN5
 perilipin 5
chr19_+_46850251 0.29 ENST00000012443.4
 PPP5C
 protein phosphatase 5, catalytic subunit
chr19_-_58951496 0.28 ENST00000254166.3
 ZNF132
 zinc finger protein 132
chr16_+_4784458 0.28 ENST00000590191.1
 C16orf71
 chromosome 16 open reading frame 71
chr2_-_230579185 0.28 ENST00000341772.4
 DNER
 delta/notch-like EGF repeat containing
chr7_+_99699280 0.28 ENST00000421755.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr12_-_4754339 0.28 ENST00000228850.1
 AKAP3
 A kinase (PRKA) anchor protein 3
chr14_+_102829300 0.28 ENST00000359520.7
 TECPR2
 tectonin beta-propeller repeat containing 2
chr5_+_176873789 0.28 ENST00000323249.3
ENST00000502922.1
 PRR7
 proline rich 7 (synaptic)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3 1.3 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 1.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 1.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 2.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.2 1.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.7 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.3 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.3 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 1.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 2.7 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 1.5 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 0.3 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 0.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.2 GO:0061568 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 1.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.9 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 1.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 1.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.4 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 1.1 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.5 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 1.0 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.0 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 1.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.0 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0070213 negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.0 GO:0071362 cellular response to ether(GO:0071362)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0097224 sperm connecting piece(GO:0097224)
0.3 1.0 GO:1902636 kinociliary basal body(GO:1902636)
0.3 1.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.3 1.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 0.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.2 0.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 0.5 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 2.4 GO:0033010 paranodal junction(GO:0033010)
0.1 3.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.4 GO:0016234 inclusion body(GO:0016234) aggresome(GO:0016235)
0.1 1.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 1.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 0.3 GO:0005119 smoothened binding(GO:0005119)
0.3 1.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.0 GO:0002046 opsin binding(GO:0002046)
0.2 1.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 1.9 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.7 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 2.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 1.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 3.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0046935 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0034618 phosphotransferase activity, carboxyl group as acceptor(GO:0016774) arginine binding(GO:0034618)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling