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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for RORC

Z-value: 0.22

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Transcription factors associated with RORC

Gene Symbol Gene ID Gene Info
ENSG00000143365.12 RORC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RORChg19_v2_chr1_-_151804314_151804348,
hg19_v2_chr1_-_151804222_151804228
0.442.8e-01Click!

Activity profile of RORC motif

Sorted Z-values of RORC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RORC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_105845674 0.31 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr4_+_85504075 0.21 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_+_26869597 0.12 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr8_-_95449155 0.11 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr19_-_49140609 0.09 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_-_19223523 0.08 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr12_-_39734783 0.08 ENST00000552961.1
KIF21A
kinesin family member 21A
chrX_-_49089771 0.07 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr6_+_43738444 0.07 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr14_-_23451845 0.07 ENST00000262713.2
AJUBA
ajuba LIM protein
chr6_-_111927062 0.07 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr1_-_217311090 0.07 ENST00000493603.1
ENST00000366940.2
ESRRG
estrogen-related receptor gamma
chr6_+_89855765 0.06 ENST00000275072.4
PM20D2
peptidase M20 domain containing 2
chr4_+_140586922 0.06 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr8_+_124780672 0.06 ENST00000521166.1
ENST00000334705.7
FAM91A1
family with sequence similarity 91, member A1
chr13_+_109248500 0.05 ENST00000356711.2
MYO16
myosin XVI
chr4_-_120243545 0.05 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr14_-_23451467 0.04 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
AJUBA
RP11-298I3.5
ajuba LIM protein
chr16_+_24266874 0.04 ENST00000005284.3
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr17_-_48785216 0.03 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr7_+_97736197 0.03 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr7_-_43965937 0.03 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
URGCP
upregulator of cell proliferation
chr3_-_45957534 0.03 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr1_+_159796534 0.03 ENST00000289707.5
SLAMF8
SLAM family member 8
chr19_+_38924316 0.03 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1
ryanodine receptor 1 (skeletal)
chr4_-_170948361 0.03 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr17_-_10707410 0.03 ENST00000581851.1
LINC00675
long intergenic non-protein coding RNA 675
chr4_+_110749143 0.03 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr7_-_141541221 0.03 ENST00000350549.3
ENST00000438520.1
PRSS37
protease, serine, 37
chr1_+_67632083 0.03 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr1_+_236849754 0.03 ENST00000542672.1
ENST00000366578.4
ACTN2
actinin, alpha 2
chr17_-_37764128 0.03 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr20_-_44007014 0.03 ENST00000372726.3
ENST00000537995.1
TP53TG5
TP53 target 5
chr1_-_240906911 0.03 ENST00000431139.2
RP11-80B9.4
RP11-80B9.4
chr1_+_171810606 0.02 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
DNM3
dynamin 3
chr14_+_21785693 0.02 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chr16_+_30937213 0.02 ENST00000427128.1
FBXL19
F-box and leucine-rich repeat protein 19
chr12_+_93964158 0.02 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr3_+_45986511 0.02 ENST00000458629.1
ENST00000457814.1
CXCR6
chemokine (C-X-C motif) receptor 6
chr19_-_8567478 0.02 ENST00000255612.3
PRAM1
PML-RARA regulated adaptor molecule 1
chr3_-_45957088 0.02 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr19_+_12780512 0.02 ENST00000242796.4
WDR83
WD repeat domain 83
chr19_-_49140692 0.02 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr12_+_93963590 0.02 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr16_-_69385681 0.02 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr19_+_55385731 0.02 ENST00000469767.1
ENST00000355524.3
ENST00000391725.3
ENST00000345937.4
ENST00000353758.4
ENST00000359272.4
ENST00000391723.3
ENST00000391724.3
FCAR
Fc fragment of IgA, receptor for
chr10_-_21435488 0.02 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113
chromosome 10 open reading frame 113
chr10_-_121296045 0.01 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr17_-_46623441 0.01 ENST00000330070.4
HOXB2
homeobox B2
chr3_+_160559931 0.01 ENST00000464260.1
ENST00000295839.9
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr2_-_148778323 0.01 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr1_-_185286461 0.01 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr11_-_47616210 0.01 ENST00000302514.3
C1QTNF4
C1q and tumor necrosis factor related protein 4
chr7_+_112063192 0.01 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr2_+_119699864 0.01 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr7_+_20686946 0.01 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_+_205197304 0.01 ENST00000358024.3
TMCC2
transmembrane and coiled-coil domain family 2
chr22_-_32860427 0.01 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr1_+_154540246 0.01 ENST00000368476.3
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr17_-_42992856 0.00 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr1_-_62190793 0.00 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr6_+_44094627 0.00 ENST00000259746.9
TMEM63B
transmembrane protein 63B
chr3_-_42452050 0.00 ENST00000441172.1
ENST00000287748.3
LYZL4
lysozyme-like 4
chr3_+_185303962 0.00 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_-_184095923 0.00 ENST00000445696.2
ENST00000204615.7
THPO
thrombopoietin
chr2_+_119699742 0.00 ENST00000327097.4
MARCO
macrophage receptor with collagenous structure

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)