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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SHOX2_HOXC5

Z-value: 1.26

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Transcription factors associated with SHOX2_HOXC5

Gene Symbol Gene ID Gene Info
SHOX2
ENSG00000168779.15 SHOX2
HOXC5
ENSG00000172789.3 HOXC5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SHOX2hg19_v2_chr3_-_157823839_1578240780.591.2e-01Click!
HOXC5hg19_v2_chr12_+_54426637_54426637-0.403.3e-01Click!

Activity profile of SHOX2_HOXC5 motif

Sorted Z-values of SHOX2_HOXC5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX2_HOXC5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_15038779 2.86 ENST00000228938.5
ENST00000539261.1
 MGP
 matrix Gla protein
chr12_-_91546926 2.71 ENST00000550758.1
 DCN
 decorin
chr5_-_20575959 2.49 ENST00000507958.1
 CDH18
 cadherin 18, type 2
chr1_-_72566613 2.20 ENST00000306821.3
 NEGR1
 neuronal growth regulator 1
chr4_-_138453606 1.77 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
 PCDH18
 protocadherin 18
chr12_-_91573132 1.73 ENST00000550563.1
ENST00000546370.1
 DCN
 decorin
chr11_+_5710919 1.57 ENST00000379965.3
ENST00000425490.1
 TRIM22
 tripartite motif containing 22
chr11_-_63376013 1.42 ENST00000540943.1
 PLA2G16
 phospholipase A2, group XVI
chr2_-_238323007 1.34 ENST00000295550.4
 COL6A3
 collagen, type VI, alpha 3
chr21_-_31852663 1.32 ENST00000390689.2
 KRTAP19-1
 keratin associated protein 19-1
chr5_-_147286065 1.31 ENST00000318315.4
ENST00000515291.1
 C5orf46
 chromosome 5 open reading frame 46
chr17_+_1674982 1.28 ENST00000572048.1
ENST00000573763.1
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chrX_+_22050546 1.27 ENST00000379374.4
 PHEX
 phosphate regulating endopeptidase homolog, X-linked
chr1_-_153518270 1.18 ENST00000354332.4
ENST00000368716.4
 S100A4
 S100 calcium binding protein A4
chr2_+_189839046 1.18 ENST00000304636.3
ENST00000317840.5
 COL3A1
 collagen, type III, alpha 1
chr1_-_145076186 1.16 ENST00000369348.3
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr6_+_136172820 1.12 ENST00000308191.6
 PDE7B
 phosphodiesterase 7B
chr12_-_91573316 1.11 ENST00000393155.1
 DCN
 decorin
chr4_-_138453559 1.08 ENST00000511115.1
 PCDH18
 protocadherin 18
chr4_-_57547870 1.04 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
 HOPX
 HOP homeobox
chr5_+_81575281 1.02 ENST00000380167.4
 ATP6AP1L
 ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_-_104916034 1.01 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
 CARD16
 caspase recruitment domain family, member 16
chr2_-_225811747 1.00 ENST00000409592.3
 DOCK10
 dedicator of cytokinesis 10
chr19_-_14945933 0.99 ENST00000322301.3
 OR7A5
 olfactory receptor, family 7, subfamily A, member 5
chr1_-_85930246 0.97 ENST00000426972.3
 DDAH1
 dimethylarginine dimethylaminohydrolase 1
chr12_-_91572278 0.95 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
 DCN
 decorin
chr9_-_21305312 0.95 ENST00000259555.4
 IFNA5
 interferon, alpha 5
chr10_-_28571015 0.94 ENST00000375719.3
ENST00000375732.1
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr19_+_50016610 0.93 ENST00000596975.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr9_+_90112767 0.92 ENST00000408954.3
 DAPK1
 death-associated protein kinase 1
chr2_+_152214098 0.88 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr4_-_57547454 0.86 ENST00000556376.2
 HOPX
 HOP homeobox
chr11_-_58612168 0.86 ENST00000287275.1
 GLYATL2
 glycine-N-acyltransferase-like 2
chr2_+_220143989 0.86 ENST00000336576.5
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr19_+_50016411 0.85 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr17_+_67498538 0.83 ENST00000589647.1
 MAP2K6
 mitogen-activated protein kinase kinase 6
chr19_-_58864848 0.83 ENST00000263100.3
 A1BG
 alpha-1-B glycoprotein
chr11_-_58611957 0.83 ENST00000532258.1
 GLYATL2
 glycine-N-acyltransferase-like 2
chr17_+_39394250 0.82 ENST00000254072.6
 KRTAP9-8
 keratin associated protein 9-8
chr16_-_66584059 0.82 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
 TK2
 thymidine kinase 2, mitochondrial
chr2_-_238322770 0.82 ENST00000472056.1
 COL6A3
 collagen, type VI, alpha 3
chr6_-_87804815 0.80 ENST00000369582.2
 CGA
 glycoprotein hormones, alpha polypeptide
chr19_-_58951496 0.80 ENST00000254166.3
 ZNF132
 zinc finger protein 132
chr20_-_33735070 0.79 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
 EDEM2
 ER degradation enhancer, mannosidase alpha-like 2
chr7_-_102184083 0.78 ENST00000379357.5
 POLR2J3
 polymerase (RNA) II (DNA directed) polypeptide J3
chr5_-_10761206 0.77 ENST00000432074.2
ENST00000230895.6
 DAP
 death-associated protein
chr6_+_52442083 0.76 ENST00000606714.1
 TRAM2-AS1
 TRAM2 antisense RNA 1 (head to head)
chr15_-_20193370 0.75 ENST00000558565.2
 IGHV3OR15-7
 immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr13_+_93879085 0.74 ENST00000377047.4
 GPC6
 glypican 6
chr17_+_66511540 0.74 ENST00000588188.2
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr16_-_66583701 0.73 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
 TK2
 thymidine kinase 2, mitochondrial
chr6_-_117747015 0.72 ENST00000368508.3
ENST00000368507.3
 ROS1
 c-ros oncogene 1 , receptor tyrosine kinase
chr16_+_77756399 0.72 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
 NUDT7
 nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr7_+_134528635 0.71 ENST00000445569.2
 CALD1
 caldesmon 1
chr5_+_119799927 0.71 ENST00000407149.2
ENST00000379551.2
 PRR16
 proline rich 16
chr19_-_44388116 0.70 ENST00000587539.1
 ZNF404
 zinc finger protein 404
chr5_+_119867159 0.70 ENST00000505123.1
 PRR16
 proline rich 16
chr12_-_10605929 0.67 ENST00000347831.5
ENST00000359151.3
 KLRC1
 killer cell lectin-like receptor subfamily C, member 1
chr2_-_238322800 0.67 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
 COL6A3
 collagen, type VI, alpha 3
chr9_-_99540328 0.66 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
 ZNF510
 zinc finger protein 510
chr17_-_43045439 0.65 ENST00000253407.3
 C1QL1
 complement component 1, q subcomponent-like 1
chr11_-_104972158 0.65 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
 CASP1
CARD16
CARD17
 caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr11_+_27015628 0.64 ENST00000318627.2
 FIBIN
 fin bud initiation factor homolog (zebrafish)
chr2_+_217524323 0.63 ENST00000456764.1
 IGFBP2
 insulin-like growth factor binding protein 2, 36kDa
chr2_+_88047606 0.63 ENST00000359481.4
 PLGLB2
 plasminogen-like B2
chr3_+_157154578 0.62 ENST00000295927.3
 PTX3
 pentraxin 3, long
chr17_-_53800217 0.62 ENST00000424486.2
 TMEM100
 transmembrane protein 100
chr4_-_140201333 0.61 ENST00000398955.1
 MGARP
 mitochondria-localized glutamic acid-rich protein
chr12_+_26348246 0.61 ENST00000422622.2
 SSPN
 sarcospan
chr22_-_32651326 0.60 ENST00000266086.4
 SLC5A4
 solute carrier family 5 (glucose activated ion channel), member 4
chr1_+_51434357 0.59 ENST00000396148.1
 CDKN2C
 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chrX_+_43515467 0.59 ENST00000338702.3
ENST00000542639.1
 MAOA
 monoamine oxidase A
chr5_+_140529630 0.59 ENST00000543635.1
 PCDHB6
 protocadherin beta 6
chr5_-_95158644 0.58 ENST00000237858.6
 GLRX
 glutaredoxin (thioltransferase)
chr6_+_31802364 0.58 ENST00000375640.3
ENST00000375641.2
 C6orf48
 chromosome 6 open reading frame 48
chr12_+_26348429 0.57 ENST00000242729.2
 SSPN
 sarcospan
chr6_+_161123270 0.57 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
 PLG
 plasminogen
chr14_-_61124977 0.56 ENST00000554986.1
 SIX1
 SIX homeobox 1
chr12_+_8309630 0.56 ENST00000396570.3
 ZNF705A
 zinc finger protein 705A
chr1_-_198509804 0.56 ENST00000489986.1
ENST00000367382.1
 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr9_+_90112590 0.56 ENST00000472284.1
 DAPK1
 death-associated protein kinase 1
chr1_+_43291220 0.55 ENST00000372514.3
 ERMAP
 erythroblast membrane-associated protein (Scianna blood group)
chr2_-_87248975 0.54 ENST00000409310.2
ENST00000355705.3
 PLGLB1
 plasminogen-like B1
chr15_+_25068773 0.53 ENST00000400100.1
ENST00000400098.1
 SNRPN
 small nuclear ribonucleoprotein polypeptide N
chr7_+_120628731 0.53 ENST00000310396.5
 CPED1
 cadherin-like and PC-esterase domain containing 1
chr7_+_141811539 0.53 ENST00000550469.2
ENST00000477922.3
 RP11-1220K2.2
 Putative inactive maltase-glucoamylase-like protein LOC93432
chr8_-_116504448 0.53 ENST00000518018.1
 TRPS1
 trichorhinophalangeal syndrome I
chr15_+_26360970 0.52 ENST00000556159.1
ENST00000557523.1
 LINC00929
 long intergenic non-protein coding RNA 929
chr4_-_57524061 0.52 ENST00000508121.1
 HOPX
 HOP homeobox
chr10_+_90660832 0.52 ENST00000371924.1
 STAMBPL1
 STAM binding protein-like 1
chr1_+_225600404 0.51 ENST00000366845.2
 AC092811.1
 AC092811.1
chrX_+_55744166 0.51 ENST00000374941.4
ENST00000414239.1
 RRAGB
 Ras-related GTP binding B
chr19_-_14064114 0.50 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
 PODNL1
 podocan-like 1
chr1_-_13052998 0.50 ENST00000436041.1
 WI2-3308P17.2
 Uncharacterized protein
chr5_+_32788945 0.50 ENST00000326958.1
 AC026703.1
 AC026703.1
chrX_-_92928557 0.50 ENST00000373079.3
ENST00000475430.2
 NAP1L3
 nucleosome assembly protein 1-like 3
chr6_+_31802685 0.49 ENST00000375639.2
ENST00000375638.3
ENST00000375635.2
ENST00000375642.2
ENST00000395789.1
 C6orf48
 chromosome 6 open reading frame 48
chr8_-_13372253 0.49 ENST00000316609.5
 DLC1
 deleted in liver cancer 1
chrX_+_86772707 0.49 ENST00000373119.4
 KLHL4
 kelch-like family member 4
chr10_-_49860525 0.49 ENST00000435790.2
 ARHGAP22
 Rho GTPase activating protein 22
chr2_+_68872954 0.48 ENST00000394342.2
 PROKR1
 prokineticin receptor 1
chr3_-_114790179 0.48 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr3_+_45927994 0.48 ENST00000357632.2
ENST00000395963.2
 CCR9
 chemokine (C-C motif) receptor 9
chr13_-_76111945 0.48 ENST00000355801.4
ENST00000406936.3
 COMMD6
 COMM domain containing 6
chr10_-_13043697 0.48 ENST00000378825.3
 CCDC3
 coiled-coil domain containing 3
chr7_+_138915102 0.47 ENST00000486663.1
 UBN2
 ubinuclein 2
chr3_-_171528227 0.47 ENST00000356327.5
ENST00000342215.6
ENST00000340989.4
ENST00000351298.4
 PLD1
 phospholipase D1, phosphatidylcholine-specific
chr7_-_92777606 0.47 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
 SAMD9L
 sterile alpha motif domain containing 9-like
chr16_+_33204156 0.47 ENST00000398667.4
 TP53TG3C
 TP53 target 3C
chr3_+_8543393 0.46 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
 LMCD1
 LIM and cysteine-rich domains 1
chr19_+_56159509 0.45 ENST00000586790.1
ENST00000591578.1
ENST00000588740.1
 CCDC106
 coiled-coil domain containing 106
chr2_-_211179883 0.45 ENST00000352451.3
 MYL1
 myosin, light chain 1, alkali; skeletal, fast
chr6_+_72926145 0.44 ENST00000425662.2
ENST00000453976.2
 RIMS1
 regulating synaptic membrane exocytosis 1
chr11_-_27722021 0.44 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
 BDNF
 brain-derived neurotrophic factor
chr3_+_138340049 0.44 ENST00000464668.1
 FAIM
 Fas apoptotic inhibitory molecule
chr8_+_104384616 0.43 ENST00000520337.1
 CTHRC1
 collagen triple helix repeat containing 1
chr19_+_45417921 0.43 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
 APOC1
 apolipoprotein C-I
chr12_-_102455846 0.42 ENST00000545679.1
 CCDC53
 coiled-coil domain containing 53
chr5_+_156696362 0.42 ENST00000377576.3
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr11_-_101000445 0.42 ENST00000534013.1
 PGR
 progesterone receptor
chr12_-_91573249 0.42 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
 DCN
 decorin
chr1_+_226013047 0.41 ENST00000366837.4
 EPHX1
 epoxide hydrolase 1, microsomal (xenobiotic)
chr10_+_89420706 0.41 ENST00000427144.2
 PAPSS2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr3_-_9994021 0.41 ENST00000411976.2
ENST00000412055.1
 PRRT3
 proline-rich transmembrane protein 3
chr12_-_58329819 0.41 ENST00000551421.1
 RP11-620J15.3
 RP11-620J15.3
chr11_-_111794446 0.40 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr9_+_12775011 0.40 ENST00000319264.3
 LURAP1L
 leucine rich adaptor protein 1-like
chr22_-_39190116 0.40 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
 SUN2
DNAL4
 Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr6_+_63921399 0.40 ENST00000356170.3
 FKBP1C
 FK506 binding protein 1C
chr2_+_161993465 0.40 ENST00000457476.1
 TANK
 TRAF family member-associated NFKB activator
chr5_-_95158375 0.40 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX
 glutaredoxin (thioltransferase)
chr11_+_15136462 0.39 ENST00000379556.3
ENST00000424273.1
 INSC
 inscuteable homolog (Drosophila)
chr11_+_77532155 0.39 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr1_+_159272111 0.39 ENST00000368114.1
 FCER1A
 Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr2_-_40680578 0.38 ENST00000455476.1
 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
chr12_-_10607084 0.38 ENST00000408006.3
ENST00000544822.1
ENST00000536188.1
 KLRC1
 killer cell lectin-like receptor subfamily C, member 1
chr15_+_94899183 0.38 ENST00000557742.1
 MCTP2
 multiple C2 domains, transmembrane 2
chr11_+_33061543 0.38 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
 TCP11L1
 t-complex 11, testis-specific-like 1
chr2_-_3521518 0.38 ENST00000382093.5
 ADI1
 acireductone dioxygenase 1
chr20_+_123010 0.38 ENST00000382398.3
 DEFB126
 defensin, beta 126
chr16_-_3074231 0.38 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
 HCFC1R1
 host cell factor C1 regulator 1 (XPO1 dependent)
chrX_-_100872911 0.38 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
 ARMCX6
 armadillo repeat containing, X-linked 6
chr11_+_77532233 0.37 ENST00000525409.1
 AAMDC
 adipogenesis associated, Mth938 domain containing
chrX_-_102510126 0.37 ENST00000372685.3
 TCEAL8
 transcription elongation factor A (SII)-like 8
chr8_-_13134045 0.37 ENST00000512044.2
 DLC1
 deleted in liver cancer 1
chr6_-_52859046 0.36 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
 GSTA4
 glutathione S-transferase alpha 4
chr12_+_7013897 0.36 ENST00000007969.8
ENST00000323702.5
 LRRC23
 leucine rich repeat containing 23
chr3_+_8543533 0.36 ENST00000454244.1
 LMCD1
 LIM and cysteine-rich domains 1
chr8_-_93978357 0.36 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
 TRIQK
 triple QxxK/R motif containing
chr11_-_124981475 0.36 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
 TMEM218
 transmembrane protein 218
chr1_+_20878932 0.36 ENST00000332947.4
 FAM43B
 family with sequence similarity 43, member B
chr18_-_32870148 0.35 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
 ZSCAN30
RP11-158H5.7
 zinc finger and SCAN domain containing 30
RP11-158H5.7
chr1_+_217804661 0.35 ENST00000366933.4
 SPATA17
 spermatogenesis associated 17
chr11_-_104905840 0.35 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
 CASP1
 caspase 1, apoptosis-related cysteine peptidase
chr3_-_164796269 0.35 ENST00000264382.3
 SI
 sucrase-isomaltase (alpha-glucosidase)
chr4_+_70894130 0.35 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
 HTN3
 histatin 3
chr11_-_124670550 0.35 ENST00000239614.4
 MSANTD2
 Myb/SANT-like DNA-binding domain containing 2
chr14_+_74417192 0.35 ENST00000554320.1
 COQ6
 coenzyme Q6 monooxygenase
chr14_+_74486043 0.35 ENST00000464394.1
ENST00000394009.3
 CCDC176
 coiled-coil domain containing 176
chrX_+_13671225 0.34 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
 TCEANC
 transcription elongation factor A (SII) N-terminal and central domain containing
chr15_-_55657428 0.34 ENST00000568543.1
 CCPG1
 cell cycle progression 1
chr6_+_73076432 0.34 ENST00000414192.2
 RIMS1
 regulating synaptic membrane exocytosis 1
chr15_-_50558223 0.33 ENST00000267845.3
 HDC
 histidine decarboxylase
chr9_-_95166841 0.33 ENST00000262551.4
 OGN
 osteoglycin
chr12_+_7014064 0.33 ENST00000443597.2
 LRRC23
 leucine rich repeat containing 23
chr6_-_111804905 0.33 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr9_-_95166884 0.33 ENST00000375561.5
 OGN
 osteoglycin
chr11_+_12766583 0.33 ENST00000361985.2
 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_+_138340067 0.33 ENST00000479848.1
 FAIM
 Fas apoptotic inhibitory molecule
chrX_+_108779004 0.33 ENST00000218004.1
 NXT2
 nuclear transport factor 2-like export factor 2
chr6_-_57086200 0.32 ENST00000468148.1
 RAB23
 RAB23, member RAS oncogene family
chr10_-_28623368 0.32 ENST00000441595.2
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr7_-_22862406 0.32 ENST00000372879.4
 TOMM7
 translocase of outer mitochondrial membrane 7 homolog (yeast)
chr12_-_10573149 0.32 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
 KLRC3
 killer cell lectin-like receptor subfamily C, member 3
chr7_+_93551011 0.32 ENST00000248564.5
 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
chr19_+_8483272 0.32 ENST00000602117.1
 MARCH2
 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr20_-_45061695 0.31 ENST00000445496.2
 ELMO2
 engulfment and cell motility 2
chr2_-_114300213 0.31 ENST00000446595.1
ENST00000416105.1
ENST00000450636.1
ENST00000416758.1
 RP11-395L14.4
 RP11-395L14.4
chr4_-_83812248 0.31 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
 SEC31A
 SEC31 homolog A (S. cerevisiae)
chr3_-_141747950 0.31 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_154928562 0.31 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
 PBXIP1
 pre-B-cell leukemia homeobox interacting protein 1
chr6_-_26235206 0.31 ENST00000244534.5
 HIST1H1D
 histone cluster 1, H1d
chr11_+_62496114 0.30 ENST00000532583.1
 TTC9C
 tetratricopeptide repeat domain 9C
chr19_-_37663332 0.30 ENST00000392157.2
 ZNF585A
 zinc finger protein 585A
chr10_-_72648541 0.30 ENST00000299299.3
 PCBD1
 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr3_+_8543561 0.30 ENST00000397386.3
 LMCD1
 LIM and cysteine-rich domains 1
chr8_+_77593448 0.30 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr20_+_5731083 0.30 ENST00000445603.1
ENST00000442185.1
 C20orf196
 chromosome 20 open reading frame 196
chr7_-_144533074 0.30 ENST00000360057.3
ENST00000378099.3
 TPK1
 thiamin pyrophosphokinase 1
chr13_-_33780133 0.30 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr2_+_237994519 0.30 ENST00000392008.2
ENST00000409334.1
ENST00000409629.1
 COPS8
 COP9 signalosome subunit 8
chr15_+_62853562 0.30 ENST00000561311.1
 TLN2
 talin 2
chr3_-_49726486 0.29 ENST00000449682.2
 MST1
 macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_-_54411255 0.29 ENST00000371377.3
 HSPB11
 heat shock protein family B (small), member 11
chr7_-_102283238 0.29 ENST00000340457.8
 UPK3BL
 uroplakin 3B-like
chr2_+_161993412 0.29 ENST00000259075.2
ENST00000432002.1
 TANK
 TRAF family member-associated NFKB activator
chr1_+_78470530 0.29 ENST00000370763.5
 DNAJB4
 DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_157217328 0.29 ENST00000392832.2
ENST00000543418.1
 VEPH1
 ventricular zone expressed PH domain-containing 1
chrX_+_55744228 0.29 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chr11_-_13517565 0.29 ENST00000282091.1
ENST00000529816.1
 PTH
 parathyroid hormone

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4 1.5 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3 1.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.3 0.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 0.8 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.3 1.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 1.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.9 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 1.8 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.2 0.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 1.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 0.7 GO:0061743 motor learning(GO:0061743)
0.2 0.5 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.4 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 1.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 1.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.6 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.4 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.3 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 2.6 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.5 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 2.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.6 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.0 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.4 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0046066 dGDP metabolic process(GO:0046066)
0.1 1.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.9 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.2 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 1.0 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.4 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.2 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.7 GO:0051775 response to redox state(GO:0051775)
0.0 0.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.7 GO:0046130 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.3 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 1.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.8 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 1.0 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.6 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.2 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.5 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.4 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 1.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.6 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 1.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 1.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 2.5 GO:0007631 feeding behavior(GO:0007631)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.2 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.6 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.7 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.0 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.2 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0044346 fibroblast apoptotic process(GO:0044346) regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.2 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0072106 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.0 0.0 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.2 GO:0046606 negative regulation of centrosome cycle(GO:0046606)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 2.0 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.4 GO:0044301 climbing fiber(GO:0044301)
0.1 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.1 1.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:1990777 protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.1 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.0 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.4 1.8 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.7 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.3 1.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.2 0.6 GO:1990405 protein antigen binding(GO:1990405)
0.2 0.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 1.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.5 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.6 GO:0089720 caspase binding(GO:0089720)
0.1 0.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.3 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.1 0.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 6.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.5 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.5 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.0 GO:0070513 death domain binding(GO:0070513)
0.1 0.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.0 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0042578 phosphoric ester hydrolase activity(GO:0042578)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.0 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 1.2 GO:0032947 protein complex scaffold(GO:0032947)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 3.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane