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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SIX5_SMARCC2_HCFC1

Z-value: 3.15

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
SIX5
ENSG00000177045.6 SIX5
SMARCC2
ENSG00000139613.7 SMARCC2
HCFC1
ENSG00000172534.9 HCFC1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HCFC1hg19_v2_chrX_-_153236819_153236978,
hg19_v2_chrX_-_153236620_153236684,
hg19_v2_chrX_-_153237258_153237295		-0.658.0e-02Click!
SMARCC2hg19_v2_chr12_-_56583243_56583293,
hg19_v2_chr12_-_56583332_56583369		0.639.4e-02Click!
SIX5hg19_v2_chr19_-_46272462_462725620.601.2e-01Click!

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_62694834 5.99 ENST00000415602.1
 TCEA2
 transcription elongation factor A (SII), 2
chr20_+_62694590 5.32 ENST00000339217.4
 TCEA2
 transcription elongation factor A (SII), 2
chr20_+_62694461 5.25 ENST00000343484.5
ENST00000395053.3
 TCEA2
 transcription elongation factor A (SII), 2
chr1_+_47799542 3.32 ENST00000471289.2
ENST00000450808.2
 CMPK1
 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr22_-_30162924 3.17 ENST00000344318.3
ENST00000397781.3
 ZMAT5
 zinc finger, matrin-type 5
chr16_-_3074231 3.11 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
 HCFC1R1
 host cell factor C1 regulator 1 (XPO1 dependent)
chr11_-_82782861 3.10 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
 RAB30
 RAB30, member RAS oncogene family
chr3_+_69788576 3.08 ENST00000352241.4
ENST00000448226.2
 MITF
 microphthalmia-associated transcription factor
chr16_-_3073933 3.04 ENST00000574151.1
 HCFC1R1
 host cell factor C1 regulator 1 (XPO1 dependent)
chr2_-_232645977 3.00 ENST00000409772.1
 PDE6D
 phosphodiesterase 6D, cGMP-specific, rod, delta
chr2_-_232646015 2.98 ENST00000287600.4
 PDE6D
 phosphodiesterase 6D, cGMP-specific, rod, delta
chr1_+_156024525 2.89 ENST00000368305.4
 LAMTOR2
 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr1_+_156024552 2.68 ENST00000368304.5
ENST00000368302.3
 LAMTOR2
 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr14_-_65569057 2.64 ENST00000555419.1
ENST00000341653.2
 MAX
 MYC associated factor X
chr10_+_111985713 2.64 ENST00000239007.7
 MXI1
 MAX interactor 1, dimerization protein
chr11_-_73309228 2.61 ENST00000356467.4
ENST00000064778.4
 FAM168A
 family with sequence similarity 168, member A
chr14_-_65569244 2.57 ENST00000557277.1
ENST00000556892.1
 MAX
 MYC associated factor X
chr14_-_73493784 2.54 ENST00000553891.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chr11_-_74109422 2.36 ENST00000298198.4
 PGM2L1
 phosphoglucomutase 2-like 1
chr22_+_30163340 2.24 ENST00000330029.6
ENST00000401406.3
 UQCR10
 ubiquinol-cytochrome c reductase, complex III subunit X
chr10_-_44144152 2.23 ENST00000395797.1
 ZNF32
 zinc finger protein 32
chr14_-_73493825 2.23 ENST00000318876.5
ENST00000556143.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chr10_-_44144292 2.22 ENST00000374433.2
 ZNF32
 zinc finger protein 32
chr11_-_134123142 2.21 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
 THYN1
 thymocyte nuclear protein 1
chr12_-_54121212 2.20 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
 CALCOCO1
 calcium binding and coiled-coil domain 1
chr12_-_54121261 2.11 ENST00000549784.1
ENST00000262059.4
 CALCOCO1
 calcium binding and coiled-coil domain 1
chr7_-_150754935 2.11 ENST00000297518.4
 CDK5
 cyclin-dependent kinase 5
chr16_-_4588762 1.96 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
 CDIP1
 cell death-inducing p53 target 1
chr10_+_104613980 1.90 ENST00000339834.5
 C10orf32
 chromosome 10 open reading frame 32
chr11_+_71791849 1.89 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr2_+_85646054 1.88 ENST00000389938.2
 SH2D6
 SH2 domain containing 6
chr4_-_8160510 1.87 ENST00000407564.3
ENST00000361737.5
ENST00000296372.8
ENST00000545242.1
ENST00000546334.1
ENST00000318888.4
ENST00000428004.2
 ABLIM2
 actin binding LIM protein family, member 2
chr15_+_55700741 1.85 ENST00000569691.1
 C15orf65
 chromosome 15 open reading frame 65
chr19_+_37569314 1.85 ENST00000304239.7
ENST00000589245.1
ENST00000337995.3
 ZNF420
 zinc finger protein 420
chr11_-_82782952 1.85 ENST00000534141.1
 RAB30
 RAB30, member RAS oncogene family
chr16_-_15149828 1.84 ENST00000566419.1
ENST00000568320.1
 NTAN1
 N-terminal asparagine amidase
chr10_+_104614008 1.83 ENST00000369883.3
 C10orf32
 chromosome 10 open reading frame 32
chr1_-_156710916 1.83 ENST00000368211.4
 MRPL24
 mitochondrial ribosomal protein L24
chr11_-_82997013 1.82 ENST00000529073.1
ENST00000529611.1
 CCDC90B
 coiled-coil domain containing 90B
chr16_-_686235 1.77 ENST00000568773.1
ENST00000565163.1
ENST00000397665.2
ENST00000397666.2
ENST00000301686.8
ENST00000338401.4
ENST00000397664.4
ENST00000568830.1
 C16orf13
 chromosome 16 open reading frame 13
chr11_-_82997371 1.77 ENST00000525503.1
 CCDC90B
 coiled-coil domain containing 90B
chr11_+_71791693 1.77 ENST00000289488.2
ENST00000447974.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr19_+_35225060 1.77 ENST00000599244.1
ENST00000392232.3
 ZNF181
 zinc finger protein 181
chr1_-_156710859 1.75 ENST00000361531.2
ENST00000412846.1
 MRPL24
 mitochondrial ribosomal protein L24
chr12_-_133532864 1.74 ENST00000536932.1
ENST00000360187.4
ENST00000392321.3
 CHFR
ZNF605
 checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
zinc finger protein 605
chr19_+_17530888 1.74 ENST00000528515.1
ENST00000543795.1
 MVB12A
 multivesicular body subunit 12A
chr19_+_17530838 1.73 ENST00000528659.1
ENST00000392702.2
ENST00000529939.1
 MVB12A
 multivesicular body subunit 12A
chr16_-_4588822 1.72 ENST00000564828.1
 CDIP1
 cell death-inducing p53 target 1
chr16_-_15149917 1.70 ENST00000287706.3
 NTAN1
 N-terminal asparagine amidase
chr8_-_38326119 1.68 ENST00000356207.5
ENST00000326324.6
 FGFR1
 fibroblast growth factor receptor 1
chr20_+_32399093 1.67 ENST00000217402.2
 CHMP4B
 charged multivesicular body protein 4B
chrX_-_64196351 1.63 ENST00000374839.3
 ZC4H2
 zinc finger, C4H2 domain containing
chr19_+_44617511 1.62 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
 ZNF225
 zinc finger protein 225
chr14_-_77923897 1.61 ENST00000343765.2
ENST00000327028.4
ENST00000556412.1
ENST00000557466.1
ENST00000448935.2
ENST00000553888.1
ENST00000557658.1
 VIPAS39
 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr17_-_26662440 1.60 ENST00000578122.1
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chrX_-_64196307 1.58 ENST00000545618.1
 ZC4H2
 zinc finger, C4H2 domain containing
chr11_+_71791359 1.58 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr8_-_38326139 1.57 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
 FGFR1
 fibroblast growth factor receptor 1
chr2_+_202316392 1.55 ENST00000194530.3
ENST00000392249.2
 STRADB
 STE20-related kinase adaptor beta
chr19_-_44860820 1.54 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
 ZNF112
 zinc finger protein 112
chr11_+_71791803 1.54 ENST00000539271.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr19_-_6604094 1.52 ENST00000597430.2
 CD70
 CD70 molecule
chrX_-_64196376 1.52 ENST00000447788.2
 ZC4H2
 zinc finger, C4H2 domain containing
chr1_+_244816237 1.52 ENST00000302550.11
 DESI2
 desumoylating isopeptidase 2
chr2_-_85645545 1.50 ENST00000409275.1
 CAPG
 capping protein (actin filament), gelsolin-like
chr19_-_54618650 1.50 ENST00000391757.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr10_-_38265517 1.49 ENST00000302609.7
 ZNF25
 zinc finger protein 25
chr17_-_26662464 1.49 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr14_-_65569186 1.48 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
 MAX
 MYC associated factor X
chr15_-_41099648 1.48 ENST00000220496.4
 DNAJC17
 DnaJ (Hsp40) homolog, subfamily C, member 17
chr19_-_54619006 1.47 ENST00000391759.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr19_-_36980455 1.47 ENST00000454319.1
ENST00000392170.2
 ZNF566
 zinc finger protein 566
chr12_+_107168418 1.43 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
 RIC8B
 RIC8 guanine nucleotide exchange factor B
chr11_-_82997420 1.43 ENST00000455220.2
ENST00000529689.1
 CCDC90B
 coiled-coil domain containing 90B
chr19_-_39390440 1.41 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2
 sirtuin 2
chr19_-_36980337 1.41 ENST00000434377.2
ENST00000424129.2
ENST00000452939.1
ENST00000427002.1
 ZNF566
 zinc finger protein 566
chr12_+_12764773 1.40 ENST00000228865.2
 CREBL2
 cAMP responsive element binding protein-like 2
chr19_-_39390350 1.40 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2
 sirtuin 2
chr9_+_104161123 1.39 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
 ZNF189
 zinc finger protein 189
chr8_+_110346546 1.39 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
 ENY2
 enhancer of yellow 2 homolog (Drosophila)
chr7_-_100888337 1.38 ENST00000223136.4
 FIS1
 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chrX_-_107334750 1.37 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
 PSMD10
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr9_-_115774453 1.36 ENST00000427548.1
 ZNF883
 zinc finger protein 883
chr1_+_244816371 1.34 ENST00000263831.7
 DESI2
 desumoylating isopeptidase 2
chr6_-_41703296 1.34 ENST00000373033.1
 TFEB
 transcription factor EB
chr19_+_44669280 1.33 ENST00000590089.1
ENST00000454662.2
 ZNF226
 zinc finger protein 226
chr11_+_86013253 1.33 ENST00000533986.1
ENST00000278483.3
 C11orf73
 chromosome 11 open reading frame 73
chr7_-_100888313 1.32 ENST00000442303.1
 FIS1
 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr5_+_178450753 1.29 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
 ZNF879
 zinc finger protein 879
chrX_-_107334790 1.29 ENST00000217958.3
 PSMD10
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr5_-_178157700 1.27 ENST00000335815.2
 ZNF354A
 zinc finger protein 354A
chr16_+_3074002 1.25 ENST00000326266.8
ENST00000574549.1
ENST00000575576.1
ENST00000253952.9
 THOC6
 THO complex 6 homolog (Drosophila)
chr17_-_43138357 1.25 ENST00000342350.5
 DCAKD
 dephospho-CoA kinase domain containing
chr16_-_4588469 1.25 ENST00000588381.1
ENST00000563332.2
 CDIP1
 cell death-inducing p53 target 1
chr5_-_171433579 1.24 ENST00000265094.5
ENST00000393802.2
 FBXW11
 F-box and WD repeat domain containing 11
chr10_+_124134201 1.23 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
 PLEKHA1
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_-_111136513 1.22 ENST00000368911.3
 CDK19
 cyclin-dependent kinase 19
chr12_+_107168342 1.20 ENST00000392837.4
 RIC8B
 RIC8 guanine nucleotide exchange factor B
chr5_+_175815732 1.20 ENST00000274787.2
 HIGD2A
 HIG1 hypoxia inducible domain family, member 2A
chr12_+_56546363 1.20 ENST00000551834.1
ENST00000552568.1
 MYL6B
 myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr12_+_56546223 1.19 ENST00000550443.1
ENST00000207437.5
 MYL6B
 myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr19_-_37958318 1.18 ENST00000316950.6
ENST00000591710.1
 ZNF569
 zinc finger protein 569
chr7_+_33169142 1.16 ENST00000242067.6
ENST00000350941.3
ENST00000396127.2
ENST00000355070.2
ENST00000354265.4
ENST00000425508.2
 BBS9
 Bardet-Biedl syndrome 9
chr11_+_36616355 1.16 ENST00000532470.2
 C11orf74
 chromosome 11 open reading frame 74
chr2_+_203776937 1.16 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
 CARF
 calcium responsive transcription factor
chr20_-_48732472 1.15 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
 UBE2V1
 ubiquitin-conjugating enzyme E2 variant 1
chr19_-_36980756 1.15 ENST00000493391.1
 ZNF566
 zinc finger protein 566
chr19_-_37958086 1.15 ENST00000592490.1
ENST00000392149.2
 ZNF569
 zinc finger protein 569
chr19_-_19030157 1.14 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
 COPE
 coatomer protein complex, subunit epsilon
chr1_+_23695680 1.14 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
 C1orf213
 chromosome 1 open reading frame 213
chr19_+_44529479 1.13 ENST00000587846.1
ENST00000187879.8
ENST00000391960.3
 ZNF222
 zinc finger protein 222
chr14_-_24701539 1.13 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
 NEDD8-MDP1
NEDD8
 NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr19_+_54606145 1.13 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
 NDUFA3
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr15_-_55700457 1.11 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
 CCPG1
 cell cycle progression 1
chr15_+_63481668 1.10 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
 RAB8B
 RAB8B, member RAS oncogene family
chr5_-_171433819 1.09 ENST00000296933.6
 FBXW11
 F-box and WD repeat domain containing 11
chr17_-_38083843 1.09 ENST00000304046.2
ENST00000579695.1
 ORMDL3
 ORM1-like 3 (S. cerevisiae)
chr19_+_4304632 1.09 ENST00000597590.1
 FSD1
 fibronectin type III and SPRY domain containing 1
chr19_-_44405941 1.08 ENST00000587128.1
 RP11-15A1.3
 RP11-15A1.3
chr19_-_51014460 1.06 ENST00000595669.1
 JOSD2
 Josephin domain containing 2
chr19_+_4304585 1.05 ENST00000221856.6
 FSD1
 fibronectin type III and SPRY domain containing 1
chr19_-_51014345 1.05 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
 JOSD2
 Josephin domain containing 2
chr2_-_202316260 1.04 ENST00000332624.3
 TRAK2
 trafficking protein, kinesin binding 2
chr16_-_67260691 1.04 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
 LRRC29
 leucine rich repeat containing 29
chr11_+_134123389 1.04 ENST00000281182.4
ENST00000537423.1
ENST00000543332.1
ENST00000374752.4
 ACAD8
 acyl-CoA dehydrogenase family, member 8
chr19_+_37862054 1.03 ENST00000483919.1
ENST00000588911.1
ENST00000436120.2
ENST00000587349.1
 ZNF527
 zinc finger protein 527
chr5_-_138775177 1.03 ENST00000302060.5
 DNAJC18
 DnaJ (Hsp40) homolog, subfamily C, member 18
chr19_-_50529193 1.02 ENST00000596445.1
ENST00000599538.1
 VRK3
 vaccinia related kinase 3
chr8_+_145159846 1.02 ENST00000532522.1
ENST00000527572.1
ENST00000527058.1
 MAF1
 MAF1 homolog (S. cerevisiae)
chr5_-_40755987 1.02 ENST00000337702.4
 TTC33
 tetratricopeptide repeat domain 33
chr19_-_51014588 1.00 ENST00000598418.1
 JOSD2
 Josephin domain containing 2
chr11_+_114310237 1.00 ENST00000539119.1
 REXO2
 RNA exonuclease 2
chr19_-_5680499 1.00 ENST00000587589.1
 C19orf70
 chromosome 19 open reading frame 70
chr5_-_64920115 0.98 ENST00000381018.3
ENST00000274327.7
 TRIM23
 tripartite motif containing 23
chr20_-_18477862 0.98 ENST00000337227.4
 RBBP9
 retinoblastoma binding protein 9
chrX_+_106045891 0.97 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
 TBC1D8B
 TBC1 domain family, member 8B (with GRAM domain)
chr19_-_44809121 0.97 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
 ZNF235
 zinc finger protein 235
chr1_+_202317815 0.97 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr14_-_68141535 0.96 ENST00000554659.1
 VTI1B
 vesicle transport through interaction with t-SNAREs 1B
chr2_+_136499287 0.96 ENST00000415164.1
 UBXN4
 UBX domain protein 4
chr19_+_44716678 0.96 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
 ZNF227
 zinc finger protein 227
chr3_-_75834722 0.96 ENST00000471541.2
 ZNF717
 zinc finger protein 717
chr19_+_44598534 0.96 ENST00000336976.6
 ZNF224
 zinc finger protein 224
chr5_-_132113559 0.95 ENST00000448933.1
 SEPT8
 septin 8
chr3_+_183892635 0.95 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
 AP2M1
 adaptor-related protein complex 2, mu 1 subunit
chr11_-_76155700 0.95 ENST00000572035.1
 RP11-111M22.3
 RP11-111M22.3
chr3_-_49466686 0.94 ENST00000273598.3
ENST00000436744.2
 NICN1
 nicolin 1
chr3_+_69928256 0.94 ENST00000394355.2
 MITF
 microphthalmia-associated transcription factor
chr19_-_44405623 0.93 ENST00000591815.1
 RP11-15A1.3
 RP11-15A1.3
chr14_+_24702099 0.93 ENST00000420554.2
 GMPR2
 guanosine monophosphate reductase 2
chr14_+_24025194 0.93 ENST00000404535.3
ENST00000288014.6
 THTPA
 thiamine triphosphatase
chr2_-_242447732 0.92 ENST00000439101.1
ENST00000424537.1
ENST00000401869.1
ENST00000436402.1
 STK25
 serine/threonine kinase 25
chr14_+_24702127 0.91 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
 GMPR2
 guanosine monophosphate reductase 2
chr1_+_47799446 0.90 ENST00000371873.5
 CMPK1
 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr14_+_24702073 0.90 ENST00000399440.2
 GMPR2
 guanosine monophosphate reductase 2
chr2_-_55459437 0.90 ENST00000401408.1
 CLHC1
 clathrin heavy chain linker domain containing 1
chr7_+_106809406 0.89 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
 HBP1
 HMG-box transcription factor 1
chr6_-_27440837 0.89 ENST00000211936.6
 ZNF184
 zinc finger protein 184
chr4_-_2420335 0.89 ENST00000503000.1
 ZFYVE28
 zinc finger, FYVE domain containing 28
chr8_-_99129338 0.88 ENST00000520507.1
 HRSP12
 heat-responsive protein 12
chr1_+_54519242 0.87 ENST00000234827.1
 TCEANC2
 transcription elongation factor A (SII) N-terminal and central domain containing 2
chr15_+_64386261 0.87 ENST00000560829.1
 SNX1
 sorting nexin 1
chr16_+_4674787 0.86 ENST00000262370.7
 MGRN1
 mahogunin ring finger 1, E3 ubiquitin protein ligase
chr10_+_103113802 0.86 ENST00000370187.3
 BTRC
 beta-transducin repeat containing E3 ubiquitin protein ligase
chr5_-_132113083 0.86 ENST00000296873.7
 SEPT8
 septin 8
chr6_-_31697255 0.86 ENST00000436437.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr17_-_18585131 0.85 ENST00000443457.1
ENST00000583002.1
 ZNF286B
 zinc finger protein 286B
chr19_+_35168567 0.85 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
 ZNF302
 zinc finger protein 302
chr20_+_46130671 0.85 ENST00000371998.3
ENST00000371997.3
 NCOA3
 nuclear receptor coactivator 3
chr12_+_133657461 0.84 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
 ZNF140
 zinc finger protein 140
chr19_+_44764031 0.84 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
 ZNF233
 zinc finger protein 233
chr16_+_68573116 0.84 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
 ZFP90
 ZFP90 zinc finger protein
chr5_-_132113036 0.83 ENST00000378706.1
 SEPT8
 septin 8
chr10_-_44070016 0.83 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
 ZNF239
 zinc finger protein 239
chr11_+_76156045 0.83 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
 C11orf30
 chromosome 11 open reading frame 30
chr3_-_183735651 0.83 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr19_-_5680231 0.83 ENST00000587950.1
 C19orf70
 chromosome 19 open reading frame 70
chr16_+_4674814 0.83 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
 MGRN1
 mahogunin ring finger 1, E3 ubiquitin protein ligase
chr1_+_1550795 0.82 ENST00000520777.1
ENST00000357210.4
ENST00000360522.4
ENST00000378710.3
ENST00000355826.5
ENST00000518681.1
ENST00000505820.2
 MIB2
 mindbomb E3 ubiquitin protein ligase 2
chr11_+_114310102 0.82 ENST00000265881.5
 REXO2
 RNA exonuclease 2
chr19_-_44439387 0.82 ENST00000269973.5
 ZNF45
 zinc finger protein 45
chr11_+_36616044 0.82 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
 C11orf74
 chromosome 11 open reading frame 74
chr21_+_35747773 0.82 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
 SMIM11
 small integral membrane protein 11
chr9_+_72435749 0.81 ENST00000480564.1
 C9orf135
 chromosome 9 open reading frame 135
chrX_-_71792477 0.81 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
 HDAC8
 histone deacetylase 8
chr4_+_159593418 0.81 ENST00000507475.1
ENST00000307738.5
 ETFDH
 electron-transferring-flavoprotein dehydrogenase
chr11_+_114310164 0.81 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
 REXO2
 RNA exonuclease 2
chr20_-_2489542 0.81 ENST00000421216.1
ENST00000381253.1
 ZNF343
 zinc finger protein 343
chr15_-_78369994 0.80 ENST00000300584.3
ENST00000409931.3
 TBC1D2B
 TBC1 domain family, member 2B
chr19_+_37709076 0.80 ENST00000590503.1
ENST00000589413.1
 ZNF383
 zinc finger protein 383
chr19_+_37341260 0.79 ENST00000589046.1
 ZNF345
 zinc finger protein 345
chr7_+_99717230 0.79 ENST00000262932.3
 CNPY4
 canopy FGF signaling regulator 4
chr19_-_47354023 0.78 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
 AP2S1
 adaptor-related protein complex 2, sigma 1 subunit
chr8_-_99129384 0.78 ENST00000521560.1
ENST00000254878.3
 HRSP12
 heat-responsive protein 12
chr14_+_24701819 0.78 ENST00000560139.1
ENST00000559910.1
 GMPR2
 guanosine monophosphate reductase 2
chr19_+_37407212 0.78 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
 ZNF568
 zinc finger protein 568
chr1_-_26232951 0.78 ENST00000426559.2
ENST00000455785.2
 STMN1
 stathmin 1
chr9_-_99540328 0.77 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
 ZNF510
 zinc finger protein 510
chr6_+_31633902 0.77 ENST00000375865.2
ENST00000375866.2
 CSNK2B
 casein kinase 2, beta polypeptide
chr1_-_23694794 0.77 ENST00000374608.3
 ZNF436
 zinc finger protein 436

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.9 2.8 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.7 3.5 GO:0019075 virus maturation(GO:0019075)
0.5 2.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.5 4.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.4 2.1 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.4 2.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 1.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 1.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.4 2.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 1.0 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 6.9 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.3 1.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 1.7 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.3 2.3 GO:0035624 receptor transactivation(GO:0035624)
0.3 2.0 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.3 1.4 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.3 3.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.3 2.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 0.8 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 2.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 2.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 16.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.3 0.5 GO:0010165 response to X-ray(GO:0010165)
0.3 0.8 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.2 1.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 0.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.9 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.2 0.9 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 0.7 GO:1904351 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.2 1.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 1.0 GO:0051697 protein delipidation(GO:0051697)
0.2 1.5 GO:0044211 CTP salvage(GO:0044211)
0.2 1.0 GO:0006574 valine catabolic process(GO:0006574)
0.2 2.6 GO:0019388 galactose catabolic process(GO:0019388)
0.2 1.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 1.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 0.6 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2 0.6 GO:0036292 DNA rewinding(GO:0036292)
0.2 0.6 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.2 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 4.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.6 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 3.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 1.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 2.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1 1.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 4.8 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 0.8 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 5.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 3.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.5 GO:0007067 mitotic nuclear division(GO:0007067)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.9 GO:0051013 microtubule severing(GO:0051013)
0.1 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 1.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 6.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 4.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.3 GO:1903336 intralumenal vesicle formation(GO:0070676) negative regulation of vacuolar transport(GO:1903336)
0.1 0.6 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.3 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 2.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.2 GO:0001553 luteinization(GO:0001553)
0.1 1.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.6 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 1.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.4 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.5 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 6.5 GO:0048678 response to axon injury(GO:0048678)
0.1 2.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 1.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.3 GO:0009183 ADP biosynthetic process(GO:0006172) purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 1.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.6 GO:1903671 negative regulation of sprouting angiogenesis(GO:1903671)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.7 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.5 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.1 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.9 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 1.1 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.1 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 3.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 5.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.1 GO:0045116 protein neddylation(GO:0045116)
0.0 5.6 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.0 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 1.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.3 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 1.9 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.6 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.5 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 1.6 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.7 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.3 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 2.7 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 2.5 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 2.1 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.2 GO:0048563 post-embryonic eye morphogenesis(GO:0048050) post-embryonic organ morphogenesis(GO:0048563)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 1.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0009314 response to radiation(GO:0009314)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0045008 depyrimidination(GO:0045008)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 4.2 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.7 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 1.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 1.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.4 GO:0098792 xenophagy(GO:0098792)
0.0 0.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 1.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.5 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.9 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle organ development(GO:0048635)
0.0 1.0 GO:0006301 postreplication repair(GO:0006301)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.9 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 0.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.0 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.0 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
1.0 3.1 GO:1902636 kinociliary basal body(GO:1902636)
0.7 4.3 GO:1902560 GMP reductase complex(GO:1902560)
0.6 5.6 GO:0071986 Ragulator complex(GO:0071986)
0.6 4.9 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.5 2.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.4 1.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.8 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.3 1.1 GO:0035339 SPOTS complex(GO:0035339)
0.3 15.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 3.5 GO:0000813 ESCRT I complex(GO:0000813)
0.2 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.2 2.8 GO:0072687 chromatin silencing complex(GO:0005677) meiotic spindle(GO:0072687)
0.2 0.9 GO:0097224 sperm connecting piece(GO:0097224)
0.2 4.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 2.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 3.7 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 1.2 GO:0002177 manchette(GO:0002177)
0.2 0.5 GO:0071203 WASH complex(GO:0071203)
0.2 0.7 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.2 7.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 2.1 GO:0030897 HOPS complex(GO:0030897)
0.1 1.4 GO:0000124 SAGA complex(GO:0000124)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.1 GO:0051286 cell tip(GO:0051286)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.9 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 3.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.2 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 0.1 GO:0034709 methylosome(GO:0034709)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 6.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 1.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 2.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 4.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 1.7 GO:0071565 nBAF complex(GO:0071565)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 6.2 GO:0070469 respiratory chain(GO:0070469)
0.1 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 1.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 1.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 1.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0019867 outer membrane(GO:0019867)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 1.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 3.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.8 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.9 2.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.8 6.8 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.7 4.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.7 2.1 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.6 3.1 GO:0002046 opsin binding(GO:0002046)
0.5 1.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.4 1.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.3 2.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 2.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 1.7 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 2.0 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.3 1.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.3 1.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3 3.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 6.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 0.7 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 4.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 2.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 6.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.7 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 0.9 GO:1990460 leptin receptor binding(GO:1990460)
0.2 10.7 GO:0070888 E-box binding(GO:0070888)
0.2 0.5 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.2 1.5 GO:0004849 uridine kinase activity(GO:0004849)
0.2 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.0 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.5 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 2.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 2.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.7 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.1 GO:0030911 TPR domain binding(GO:0030911)
0.1 1.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.3 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 1.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 1.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 3.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 2.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 3.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.7 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.7 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 5.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 1.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 5.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.0 2.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0015266 protein channel activity(GO:0015266)
0.0 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 1.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 9.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.2 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 2.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 5.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 35.2 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 15.0 GO:0008270 zinc ion binding(GO:0008270)
0.0 3.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.5 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 8.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105) transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 2.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.5 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.0 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 7.5 PID MYC PATHWAY C-MYC pathway
0.1 2.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 5.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 1.4 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.2 4.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 3.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 4.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 9.7 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 1.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 39.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 6.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.2 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 1.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 2.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening