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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SPI1

Z-value: 1.43

Motif logo

Transcription factors associated with SPI1

Gene Symbol Gene ID Gene Info
ENSG00000066336.7 SPI1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPI1hg19_v2_chr11_-_47400062_474000770.821.3e-02Click!

Activity profile of SPI1 motif

Sorted Z-values of SPI1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPI1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_124194875 2.52 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr2_-_161056762 2.38 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr2_+_233925064 2.36 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr2_-_161056802 2.34 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr8_+_124194752 2.28 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr1_-_201368653 1.72 ENST00000367313.3
LAD1
ladinin 1
chr1_-_201368707 1.71 ENST00000391967.2
LAD1
ladinin 1
chr10_-_98031265 1.51 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr1_-_183560011 1.43 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr2_+_69001913 1.41 ENST00000409030.3
ENST00000409220.1
ARHGAP25
Rho GTPase activating protein 25
chr19_+_45281118 1.38 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr10_-_98031310 1.35 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr18_+_61445007 1.35 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr6_+_125524785 1.34 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr12_-_51785182 1.26 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr4_+_100737954 1.26 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr2_+_85360499 1.20 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr18_+_21452964 1.20 ENST00000587184.1
LAMA3
laminin, alpha 3
chr19_+_35739897 1.18 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR
lipolysis stimulated lipoprotein receptor
chr18_+_21452804 1.17 ENST00000269217.6
LAMA3
laminin, alpha 3
chr11_+_128563652 1.13 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr19_+_35739782 1.12 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr1_-_175162048 1.10 ENST00000444639.1
KIAA0040
KIAA0040
chr15_+_41136586 1.10 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr1_-_183559693 1.03 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr8_+_22438009 1.02 ENST00000409417.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr14_+_65171315 1.02 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_-_6740802 1.00 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr2_+_68961934 0.97 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr3_-_121379739 0.96 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr2_+_68961905 0.95 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr1_-_207095324 0.92 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr11_-_72432950 0.91 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_-_72433346 0.89 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_-_27135591 0.88 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr1_+_153330322 0.88 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr8_-_134309335 0.87 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr5_+_35856951 0.87 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr2_+_182321925 0.86 ENST00000339307.4
ENST00000397033.2
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr12_+_7055767 0.84 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr7_+_86273700 0.84 ENST00000546348.1
GRM3
glutamate receptor, metabotropic 3
chr2_-_64371546 0.82 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr6_-_11779014 0.81 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr20_+_58630972 0.81 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr8_+_82644669 0.79 ENST00000297265.4
CHMP4C
charged multivesicular body protein 4C
chr6_-_11779174 0.79 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr7_+_86273952 0.78 ENST00000536043.1
GRM3
glutamate receptor, metabotropic 3
chr22_+_40390930 0.78 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr7_+_86274145 0.78 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
GRM3
glutamate receptor, metabotropic 3
chr1_+_186798073 0.77 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr12_+_7055631 0.77 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_11779403 0.77 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr1_-_175161890 0.76 ENST00000545251.2
ENST00000423313.1
KIAA0040
KIAA0040
chr12_-_6484715 0.76 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr14_+_67999999 0.76 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr6_-_42419649 0.75 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr2_+_68962014 0.74 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr11_+_1861399 0.74 ENST00000381905.3
TNNI2
troponin I type 2 (skeletal, fast)
chr2_-_235405168 0.73 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr9_-_117150243 0.72 ENST00000374088.3
AKNA
AT-hook transcription factor
chr19_-_4338838 0.71 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr6_+_18387570 0.71 ENST00000259939.3
RNF144B
ring finger protein 144B
chr19_-_4338783 0.70 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr11_+_66824276 0.70 ENST00000308831.2
RHOD
ras homolog family member D
chr17_-_34079897 0.70 ENST00000254466.6
ENST00000587565.1
GAS2L2
growth arrest-specific 2 like 2
chr12_+_20848282 0.69 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr12_+_20848377 0.69 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr1_+_152881014 0.68 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr12_-_54785054 0.67 ENST00000352268.6
ENST00000549962.1
ZNF385A
zinc finger protein 385A
chr11_+_18154059 0.64 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chr15_+_77287426 0.64 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_+_16083154 0.64 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr11_+_1860832 0.63 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr1_+_9711781 0.62 ENST00000536656.1
ENST00000377346.4
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr15_+_90744533 0.62 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_+_128563948 0.62 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_-_35230434 0.62 ENST00000504500.1
PRLR
prolactin receptor
chr8_+_86089460 0.60 ENST00000418930.2
E2F5
E2F transcription factor 5, p130-binding
chr8_+_56792377 0.60 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr11_+_66824346 0.59 ENST00000532559.1
RHOD
ras homolog family member D
chr8_+_56792355 0.59 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_27286897 0.59 ENST00000320567.5
C1orf172
chromosome 1 open reading frame 172
chr14_+_65171099 0.59 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_+_42104692 0.57 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr1_-_156786634 0.56 ENST00000392306.2
ENST00000368199.3
SH2D2A
SH2 domain containing 2A
chr1_-_156786530 0.55 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr8_+_86089619 0.55 ENST00000256117.5
ENST00000416274.2
E2F5
E2F transcription factor 5, p130-binding
chr4_-_89152474 0.55 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr3_+_193853927 0.54 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr20_+_1875110 0.53 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr17_+_7461613 0.53 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7461781 0.53 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_25256368 0.53 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr3_-_112693865 0.52 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1
CD200 receptor 1
chr2_-_96811170 0.52 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr17_-_38256973 0.51 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr2_+_113931513 0.51 ENST00000245796.6
ENST00000441564.3
PSD4
pleckstrin and Sec7 domain containing 4
chr17_+_7461849 0.50 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr16_+_29674540 0.50 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr18_-_53177984 0.50 ENST00000543082.1
TCF4
transcription factor 4
chr15_-_64385981 0.48 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr16_+_4845379 0.48 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr14_-_67859422 0.48 ENST00000556532.1
PLEK2
pleckstrin 2
chr16_+_57673430 0.48 ENST00000540164.2
ENST00000568531.1
GPR56
G protein-coupled receptor 56
chrX_-_128788914 0.48 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr2_-_31360887 0.47 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_-_47220335 0.47 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
PRKD2
protein kinase D2
chr18_-_47721447 0.46 ENST00000285039.7
MYO5B
myosin VB
chr6_-_33267101 0.46 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr19_+_41281282 0.46 ENST00000263369.3
MIA
melanoma inhibitory activity
chr3_-_11762202 0.45 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4
vestigial like 4 (Drosophila)
chr6_-_116381918 0.45 ENST00000606080.1
FRK
fyn-related kinase
chr20_+_35201993 0.45 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr11_+_120081475 0.45 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr1_-_114429997 0.45 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr15_-_64386120 0.45 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr14_-_54421190 0.45 ENST00000417573.1
BMP4
bone morphogenetic protein 4
chr17_+_9728828 0.44 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr18_-_52989217 0.44 ENST00000570287.2
TCF4
transcription factor 4
chr2_-_69098566 0.44 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr5_+_68530697 0.43 ENST00000256443.3
ENST00000514676.1
CDK7
cyclin-dependent kinase 7
chr11_+_394196 0.43 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr19_+_17862274 0.43 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCHO1
FCH domain only 1
chr14_-_34420259 0.43 ENST00000250457.3
ENST00000547327.2
EGLN3
egl-9 family hypoxia-inducible factor 3
chr1_+_31883048 0.43 ENST00000536859.1
SERINC2
serine incorporator 2
chr7_-_45018686 0.42 ENST00000258787.7
MYO1G
myosin IG
chr2_+_103035102 0.42 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr3_-_142681399 0.42 ENST00000492509.1
PAQR9
progestin and adipoQ receptor family member IX
chr4_-_40631859 0.42 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr17_-_41738931 0.42 ENST00000329168.3
ENST00000549132.1
MEOX1
mesenchyme homeobox 1
chr14_+_77924204 0.41 ENST00000555133.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr5_+_68530668 0.41 ENST00000506563.1
CDK7
cyclin-dependent kinase 7
chr19_+_1077393 0.41 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr14_+_102276192 0.41 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr1_-_226926864 0.40 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr2_+_182850551 0.40 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_11696464 0.39 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr5_+_180467219 0.39 ENST00000376841.2
ENST00000327705.9
ENST00000376842.3
BTNL9
butyrophilin-like 9
chr4_-_185395672 0.38 ENST00000393593.3
IRF2
interferon regulatory factor 2
chrX_+_82763265 0.38 ENST00000373200.2
POU3F4
POU class 3 homeobox 4
chr7_+_129847688 0.38 ENST00000297819.3
SSMEM1
serine-rich single-pass membrane protein 1
chr17_+_7461580 0.38 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr16_+_2205755 0.37 ENST00000326181.6
TRAF7
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr12_+_6493406 0.37 ENST00000543190.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr14_-_21490958 0.37 ENST00000554104.1
NDRG2
NDRG family member 2
chr2_+_177134201 0.37 ENST00000452865.1
MTX2
metaxin 2
chr2_+_182850743 0.36 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr7_+_144052381 0.36 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr20_+_35201857 0.36 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr17_-_38938786 0.35 ENST00000301656.3
KRT27
keratin 27
chr14_+_77924373 0.35 ENST00000216479.3
ENST00000535854.2
ENST00000555517.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr1_-_155947951 0.35 ENST00000313695.7
ENST00000497907.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr18_-_52989525 0.35 ENST00000457482.3
TCF4
transcription factor 4
chr17_+_21191341 0.35 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr1_+_81771806 0.34 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr5_-_88179302 0.34 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr17_+_39382900 0.34 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr15_-_55489097 0.34 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr4_-_156298087 0.34 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr6_+_90604188 0.34 ENST00000369352.1
GJA10
gap junction protein, alpha 10, 62kDa
chr5_+_176784837 0.34 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chrX_-_30993201 0.33 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_236557569 0.33 ENST00000334232.4
EDARADD
EDAR-associated death domain
chr6_-_29343068 0.33 ENST00000396806.3
OR12D3
olfactory receptor, family 12, subfamily D, member 3
chr10_-_75676400 0.33 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr6_-_42418999 0.33 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr6_-_52109335 0.32 ENST00000336123.4
IL17F
interleukin 17F
chr2_+_85804614 0.32 ENST00000263864.5
ENST00000409760.1
VAMP8
vesicle-associated membrane protein 8
chr16_+_84682108 0.32 ENST00000564996.1
ENST00000258157.5
ENST00000567410.1
KLHL36
kelch-like family member 36
chr1_-_235098935 0.32 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr4_+_81256871 0.32 ENST00000358105.3
ENST00000508675.1
C4orf22
chromosome 4 open reading frame 22
chr6_-_6007200 0.32 ENST00000244766.2
NRN1
neuritin 1
chr9_+_103204553 0.32 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_+_34642656 0.32 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr17_+_74261277 0.31 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr6_+_139349817 0.31 ENST00000367660.3
ABRACL
ABRA C-terminal like
chrX_+_128913906 0.31 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr12_-_50616382 0.31 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr12_-_123201337 0.31 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_+_54447637 0.31 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr17_+_6918064 0.31 ENST00000546760.1
ENST00000552402.1
C17orf49
chromosome 17 open reading frame 49
chr4_+_103423055 0.31 ENST00000505458.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_-_32160622 0.31 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr8_-_102217515 0.31 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
ZNF706
zinc finger protein 706
chr12_-_50616122 0.30 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr4_+_103422471 0.30 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr19_+_49838653 0.30 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr14_-_45431091 0.30 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr16_-_4401258 0.30 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr1_+_174846570 0.30 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr14_+_92980111 0.30 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr6_+_31543334 0.30 ENST00000449264.2
TNF
tumor necrosis factor
chr11_-_58343319 0.30 ENST00000395074.2
LPXN
leupaxin
chr20_-_23030296 0.30 ENST00000377103.2
THBD
thrombomodulin
chr1_-_157522260 0.30 ENST00000368191.3
ENST00000361835.3
FCRL5
Fc receptor-like 5
chr17_+_6918354 0.30 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr18_-_53068911 0.29 ENST00000537856.3
TCF4
transcription factor 4
chr18_-_53069419 0.29 ENST00000570177.2
TCF4
transcription factor 4
chr3_-_47324242 0.29 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9
kinesin family member 9
chr17_+_6918093 0.29 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5 2.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.5 1.8 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.4 4.6 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.4 1.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.4 1.2 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.3 1.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 0.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.7 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 2.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 0.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.5 GO:2000974 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.5 GO:0070859 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.2 2.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 0.8 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.2 0.5 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 1.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.4 GO:0061151 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.9 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 1.0 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.5 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.4 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.4 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.6 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1 0.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.5 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 1.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.1 GO:0060458 right lung development(GO:0060458)
0.1 0.5 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.3 GO:0010693 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) negative regulation of alkaline phosphatase activity(GO:0010693) positive regulation of translational initiation by iron(GO:0045994) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.9 GO:0021603 cranial nerve formation(GO:0021603)
0.1 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 2.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 0.3 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.9 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.1 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.1 0.6 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.3 GO:0046203 spermidine catabolic process(GO:0046203)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.6 GO:0032439 endosome localization(GO:0032439)
0.1 0.3 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 1.4 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) protein kinase D signaling(GO:0089700)
0.1 0.6 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.5 GO:0030578 PML body organization(GO:0030578)
0.1 0.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.2 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.2 GO:0014744 positive regulation of muscle adaptation(GO:0014744)
0.1 0.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 2.4 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.9 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.3 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.2 GO:0036336 dendritic cell migration(GO:0036336)
0.1 0.2 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.6 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 1.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0048290 isotype switching to IgA isotypes(GO:0048290)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0031947 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.4 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.4 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.7 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 1.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 1.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.2 GO:0098761 interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.0 0.9 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 1.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:0032214 regulation of telomere maintenance via semi-conservative replication(GO:0032213) negative regulation of telomere maintenance via semi-conservative replication(GO:0032214)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.4 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 2.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.0 GO:0032752 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.0 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.7 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.0 GO:0008355 olfactory learning(GO:0008355)
0.0 0.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.0 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.4 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.4 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 2.5 GO:0032010 phagolysosome(GO:0032010)
0.3 2.4 GO:0005610 laminin-5 complex(GO:0005610)
0.3 2.3 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 0.8 GO:0070985 TFIIK complex(GO:0070985)
0.1 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0097361 CIA complex(GO:0097361)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 2.3 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.6 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 2.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.0 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.4 2.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 4.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 2.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 2.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.9 GO:1990405 protein antigen binding(GO:1990405)
0.1 1.4 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.1 2.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 1.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.2 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 2.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.9 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 4.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0030305 heparanase activity(GO:0030305)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0052723 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 2.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.4 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 0.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 3.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 3.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 2.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.0 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 6.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 2.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding