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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SPIC

Z-value: 1.51

Motif logo

Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
ENSG00000166211.6 SPIC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIChg19_v2_chr12_+_101869096_1018691990.314.6e-01Click!

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_68678739 2.73 ENST00000264012.4
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr16_+_68678892 2.64 ENST00000429102.2
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr12_-_51785182 1.70 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr2_-_113594279 1.65 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr10_-_99161033 1.63 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr15_+_90744533 1.58 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_-_175161890 1.58 ENST00000545251.2
ENST00000423313.1
KIAA0040
KIAA0040
chr2_+_182321925 1.57 ENST00000339307.4
ENST00000397033.2
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr4_-_89152474 1.57 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr6_-_11779403 1.56 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr19_-_51456321 1.51 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr19_-_51456344 1.50 ENST00000336334.3
ENST00000593428.1
KLK5
kallikrein-related peptidase 5
chr3_-_111314230 1.41 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr11_-_102668879 1.39 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr1_-_183560011 1.34 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr6_-_11779174 1.32 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr6_-_11779014 1.22 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr11_+_1861399 1.22 ENST00000381905.3
TNNI2
troponin I type 2 (skeletal, fast)
chr19_-_51456198 1.20 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr10_-_98031265 1.13 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr3_+_130613226 1.13 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr1_+_161676983 1.12 ENST00000367957.2
FCRLA
Fc receptor-like A
chr3_+_130612803 1.11 ENST00000510168.1
ENST00000508532.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr16_+_30194916 1.07 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr1_+_161677034 1.07 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA
Fc receptor-like A
chr3_+_130613001 1.05 ENST00000504948.1
ENST00000513801.1
ENST00000505072.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr15_+_80987617 1.00 ENST00000258884.4
ENST00000558464.1
ABHD17C
abhydrolase domain containing 17C
chr10_-_98031310 0.98 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr4_+_84457529 0.97 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr6_-_11779840 0.96 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr2_+_163175394 0.96 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr4_+_84457250 0.94 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr6_+_106534192 0.94 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chrX_+_30233668 0.93 ENST00000378988.4
MAGEB2
melanoma antigen family B, 2
chr17_-_76123101 0.93 ENST00000392467.3
TMC6
transmembrane channel-like 6
chr11_+_1860832 0.92 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr1_+_233463507 0.91 ENST00000366623.3
ENST00000366624.3
MLK4
Mitogen-activated protein kinase kinase kinase MLK4
chr19_+_38755042 0.90 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr2_+_102608306 0.90 ENST00000332549.3
IL1R2
interleukin 1 receptor, type II
chr6_+_111580508 0.89 ENST00000368847.4
KIAA1919
KIAA1919
chr4_-_80994210 0.87 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr11_-_119993979 0.87 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr5_-_78281775 0.85 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr8_-_124054587 0.84 ENST00000259512.4
DERL1
derlin 1
chr1_-_183559693 0.84 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr4_-_80994619 0.82 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr13_-_46756351 0.81 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_8243968 0.81 ENST00000520004.1
SGK223
Tyrosine-protein kinase SgK223
chr16_+_82068830 0.81 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_8201091 0.80 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr1_+_24645807 0.79 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr12_+_8975061 0.78 ENST00000299698.7
A2ML1
alpha-2-macroglobulin-like 1
chr2_-_70780572 0.75 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr9_-_33473882 0.75 ENST00000455041.2
ENST00000353159.2
ENST00000297990.4
ENST00000379471.2
NOL6
nucleolar protein 6 (RNA-associated)
chr4_-_80994471 0.73 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr16_+_69373323 0.69 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr8_+_32579341 0.69 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr1_+_24645865 0.69 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_161676739 0.68 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA
Fc receptor-like A
chr12_-_8218997 0.67 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr15_+_77287426 0.65 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr17_-_29641104 0.64 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr12_-_54778471 0.64 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr2_-_69098566 0.64 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr7_-_22234381 0.64 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_44440575 0.63 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr18_-_74839891 0.63 ENST00000581878.1
MBP
myelin basic protein
chr8_-_124054484 0.62 ENST00000419562.2
DERL1
derlin 1
chr3_-_116163830 0.62 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chrX_+_100075368 0.62 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr19_-_51471362 0.62 ENST00000376853.4
ENST00000424910.2
KLK6
kallikrein-related peptidase 6
chr3_+_32433363 0.62 ENST00000465248.1
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr12_-_95044309 0.61 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr8_-_144655141 0.61 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr6_+_14117872 0.61 ENST00000379153.3
CD83
CD83 molecule
chr19_-_51471381 0.61 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr8_-_124054362 0.60 ENST00000405944.3
DERL1
derlin 1
chr11_-_119993734 0.60 ENST00000533302.1
TRIM29
tripartite motif containing 29
chr19_+_49838653 0.58 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr16_-_88717482 0.57 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr14_-_23285069 0.56 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr5_-_140013275 0.56 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr16_+_81812863 0.56 ENST00000359376.3
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr11_-_75236867 0.55 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr16_+_69373661 0.55 ENST00000254941.6
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr2_+_102972363 0.54 ENST00000409599.1
IL18R1
interleukin 18 receptor 1
chr14_-_23285011 0.53 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_-_5304432 0.53 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr7_-_91509986 0.53 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chrX_-_40594755 0.53 ENST00000324817.1
MED14
mediator complex subunit 14
chr17_+_34431212 0.53 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr1_-_25256368 0.52 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr6_-_136571400 0.52 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2
mitochondrial fission regulator 2
chr6_+_116782527 0.52 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr3_-_123512688 0.51 ENST00000475616.1
MYLK
myosin light chain kinase
chr3_+_121796697 0.51 ENST00000482356.1
ENST00000393627.2
CD86
CD86 molecule
chr8_-_104427313 0.50 ENST00000297578.4
SLC25A32
solute carrier family 25 (mitochondrial folate carrier), member 32
chr2_-_101925055 0.50 ENST00000295317.3
RNF149
ring finger protein 149
chr16_-_72206034 0.50 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr9_+_134000948 0.50 ENST00000359428.5
ENST00000411637.2
ENST00000451030.1
NUP214
nucleoporin 214kDa
chr12_+_7055767 0.50 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_-_161015752 0.50 ENST00000435396.1
ENST00000368021.3
USF1
upstream transcription factor 1
chr3_-_156272924 0.50 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chrX_+_138612889 0.50 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr3_+_46283916 0.49 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chr16_-_23652570 0.49 ENST00000261584.4
PALB2
partner and localizer of BRCA2
chr11_-_57194550 0.49 ENST00000528187.1
ENST00000524863.1
ENST00000533051.1
ENST00000529494.1
ENST00000395124.1
ENST00000533524.1
ENST00000533245.1
ENST00000530316.1
SLC43A3
solute carrier family 43, member 3
chr3_+_46283863 0.49 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chr1_-_161014731 0.48 ENST00000368020.1
USF1
upstream transcription factor 1
chr17_+_72426891 0.48 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_+_139349817 0.48 ENST00000367660.3
ABRACL
ABRA C-terminal like
chr5_+_82373379 0.48 ENST00000396027.4
ENST00000511817.1
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr2_-_163175133 0.47 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr1_-_212588157 0.47 ENST00000261455.4
ENST00000535273.1
TMEM206
transmembrane protein 206
chr20_+_1875110 0.47 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr12_+_132413739 0.46 ENST00000443358.2
PUS1
pseudouridylate synthase 1
chr1_-_47069886 0.46 ENST00000371946.4
ENST00000371945.4
ENST00000428112.2
ENST00000529170.1
MKNK1
MAP kinase interacting serine/threonine kinase 1
chr2_-_180871780 0.46 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr6_+_116601265 0.46 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr5_+_82373317 0.45 ENST00000282268.3
ENST00000338635.6
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr10_+_44101850 0.45 ENST00000361807.3
ENST00000374437.2
ENST00000430885.1
ENST00000374435.3
ZNF485
zinc finger protein 485
chr10_+_37414785 0.45 ENST00000374660.1
ENST00000602533.1
ENST00000361713.1
ANKRD30A
ankyrin repeat domain 30A
chr3_+_57541975 0.45 ENST00000487257.1
ENST00000311180.8
PDE12
phosphodiesterase 12
chr2_+_62423242 0.44 ENST00000301998.4
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr2_+_113299990 0.44 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr12_+_133066137 0.44 ENST00000434748.2
FBRSL1
fibrosin-like 1
chr3_+_32433154 0.44 ENST00000334983.5
ENST00000349718.4
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr19_-_16653226 0.44 ENST00000198939.6
CHERP
calcium homeostasis endoplasmic reticulum protein
chr1_-_47069955 0.44 ENST00000341183.5
ENST00000496619.1
MKNK1
MAP kinase interacting serine/threonine kinase 1
chr14_+_96722539 0.44 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr3_+_101659682 0.43 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr1_-_246729544 0.43 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr14_+_77924204 0.42 ENST00000555133.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr11_-_64885111 0.42 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr4_-_111119804 0.42 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr1_+_44435646 0.42 ENST00000255108.3
ENST00000412950.2
ENST00000396758.2
DPH2
DPH2 homolog (S. cerevisiae)
chr19_-_16653325 0.42 ENST00000546361.2
CHERP
calcium homeostasis endoplasmic reticulum protein
chr3_+_148583043 0.42 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr6_+_12290586 0.42 ENST00000379375.5
EDN1
endothelin 1
chr2_+_128848740 0.42 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr3_+_124303539 0.41 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr7_-_108209897 0.41 ENST00000313516.5
THAP5
THAP domain containing 5
chr1_+_212208919 0.41 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr22_+_42196666 0.41 ENST00000402061.3
ENST00000255784.5
CCDC134
coiled-coil domain containing 134
chr1_+_116519112 0.41 ENST00000369503.4
SLC22A15
solute carrier family 22, member 15
chr4_-_103682071 0.41 ENST00000505239.1
MANBA
mannosidase, beta A, lysosomal
chr14_+_77924373 0.41 ENST00000216479.3
ENST00000535854.2
ENST00000555517.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr6_+_112375275 0.41 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
WISP3
WNT1 inducible signaling pathway protein 3
chr12_-_54785054 0.41 ENST00000352268.6
ENST00000549962.1
ZNF385A
zinc finger protein 385A
chr2_+_32390925 0.41 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr16_+_81528948 0.41 ENST00000539778.2
CMIP
c-Maf inducing protein
chr12_+_132413798 0.40 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
PUS1
pseudouridylate synthase 1
chr6_-_116381918 0.40 ENST00000606080.1
FRK
fyn-related kinase
chr17_+_18684563 0.40 ENST00000476139.1
TVP23B
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr5_+_179220979 0.39 ENST00000292596.10
ENST00000401985.3
LTC4S
leukotriene C4 synthase
chr16_-_88717423 0.39 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chrX_+_24072833 0.39 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr3_-_121264848 0.39 ENST00000264233.5
POLQ
polymerase (DNA directed), theta
chr12_+_132413765 0.39 ENST00000376649.3
ENST00000322060.5
PUS1
pseudouridylate synthase 1
chr19_-_47290535 0.38 ENST00000412532.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr11_-_72463421 0.38 ENST00000393609.3
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr22_+_37309662 0.38 ENST00000403662.3
ENST00000262825.5
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr19_+_19496728 0.38 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr1_+_6086354 0.38 ENST00000389632.4
ENST00000428161.1
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr17_+_72427477 0.38 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr16_-_88851618 0.38 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr12_+_7055631 0.37 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_+_57435219 0.37 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr3_+_142720366 0.37 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP
U2 snRNP-associated SURP domain containing
chr8_-_86253888 0.37 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr6_+_111303218 0.37 ENST00000441448.2
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr1_-_156698591 0.37 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr7_+_108210012 0.37 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr12_+_124086632 0.37 ENST00000238146.4
ENST00000538744.1
DDX55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr1_-_209957882 0.36 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chr8_-_74205851 0.36 ENST00000396467.1
RPL7
ribosomal protein L7
chr22_+_47016277 0.36 ENST00000406902.1
GRAMD4
GRAM domain containing 4
chr5_+_121297650 0.36 ENST00000339397.4
SRFBP1
serum response factor binding protein 1
chr19_+_45542295 0.36 ENST00000221455.3
ENST00000391953.4
ENST00000588936.1
CLASRP
CLK4-associating serine/arginine rich protein
chr12_+_1800179 0.36 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr17_-_43487780 0.36 ENST00000532038.1
ENST00000528677.1
ARHGAP27
Rho GTPase activating protein 27
chr18_-_52989217 0.35 ENST00000570287.2
TCF4
transcription factor 4
chr18_-_53253323 0.35 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr1_-_9129598 0.35 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr17_-_7193711 0.35 ENST00000571464.1
YBX2
Y box binding protein 2
chr1_-_150738261 0.35 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr3_+_130569429 0.35 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chrX_-_30877837 0.35 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr6_+_49431073 0.35 ENST00000335783.3
CENPQ
centromere protein Q
chr17_+_46537697 0.34 ENST00000579972.1
RP11-433M22.2
RP11-433M22.2
chr19_-_54804173 0.34 ENST00000391744.3
ENST00000251390.3
LILRA3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr3_+_5229356 0.34 ENST00000256497.4
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr13_+_41363581 0.34 ENST00000338625.4
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr9_+_273038 0.34 ENST00000487230.1
ENST00000469391.1
DOCK8
dedicator of cytokinesis 8
chr1_-_94147385 0.34 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr20_-_18774614 0.34 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr12_+_12223867 0.34 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr5_-_74062930 0.34 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
GFM2
G elongation factor, mitochondrial 2
chr1_-_156698181 0.34 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chrX_-_153237258 0.34 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0032771 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.7 4.2 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.7 4.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.5 1.6 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4 1.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.4 0.8 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.4 1.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.3 2.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 1.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 0.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 0.7 GO:0097359 UDP-glucosylation(GO:0097359)
0.2 0.9 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 1.0 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 1.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.2 0.9 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.2 1.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.2 0.5 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 0.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 1.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 0.5 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.5 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.2 0.5 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 1.0 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.2 0.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 1.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.4 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.4 GO:1905154 negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417)
0.1 0.6 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 1.6 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.5 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.6 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.6 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.3 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.7 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.4 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.6 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.6 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0019046 release from viral latency(GO:0019046)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.2 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 1.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.2 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.2 GO:1903542 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.1 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.1 0.4 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.4 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.4 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.1 0.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 2.4 GO:0045730 respiratory burst(GO:0045730)
0.1 0.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725) negative regulation of interleukin-13 production(GO:0032696)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 1.2 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.2 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.2 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.9 GO:0075713 establishment of integrated proviral latency(GO:0075713)
0.1 0.2 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.1 0.5 GO:0006477 protein sulfation(GO:0006477)
0.1 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.5 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.3 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.5 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.6 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 2.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 1.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 1.6 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:1904764 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.3 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 1.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 2.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.6 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 2.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:1990539 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:2000416 regulation of eosinophil migration(GO:2000416)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 1.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.5 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.3 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.0 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.4 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.5 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0002292 T cell differentiation involved in immune response(GO:0002292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 2.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.4 1.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.3 2.5 GO:0032010 phagolysosome(GO:0032010)
0.2 0.6 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 0.5 GO:0072563 endothelial microparticle(GO:0072563)
0.2 0.9 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 0.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.0 GO:0016589 NURF complex(GO:0016589)
0.1 0.4 GO:1990031 pinceau fiber(GO:1990031)
0.1 0.5 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.1 GO:0005861 troponin complex(GO:0005861)
0.1 2.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.1 0.9 GO:0005916 fascia adherens(GO:0005916)
0.1 2.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 6.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.1 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0034686 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0030684 preribosome(GO:0030684) small-subunit processome(GO:0032040)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 2.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.0 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 3.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.3 0.8 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 0.7 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 1.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.2 0.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.5 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 0.9 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 2.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 0.5 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.2 0.5 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 2.1 GO:0031014 troponin T binding(GO:0031014)
0.1 0.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 3.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.4 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 2.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.3 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 1.0 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.2 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.1 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.1 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.7 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.9 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.5 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 5.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.2 5.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 4.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.9 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 2.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis