Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
TBP Links Ensembl NCBI GeneCards UniProt	ENSG00000112592.8	TBP

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TBP	hg19_v2_chr6_+_170863421_170863484	0.28	5.0e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr12_-_52845910	3.82	ENST00000252252.3	KRT6B	keratin 6B
chr1_+_153003671	2.79	ENST00000307098.4	SPRR1B	small proline-rich protein 1B
chr12_-_52867569	2.65	ENST00000252250.6	KRT6C	keratin 6C
chr11_+_18287721	2.20	ENST00000356524.4	SAA1	serum amyloid A1
chr11_+_18287801	2.18	ENST00000532858.1 ENST00000405158.2	SAA1	serum amyloid A1
chr19_-_6720686	2.17	ENST00000245907.6	C3	complement component 3
chr11_-_18270182	1.99	ENST00000528349.1 ENST00000526900.1 ENST00000529528.1 ENST00000414546.2 ENST00000256733.4	SAA2	serum amyloid A2
chr17_-_39674668	1.85	ENST00000393981.3	KRT15	keratin 15
chr1_-_153363452	1.78	ENST00000368732.1 ENST00000368733.3	S100A8	S100 calcium binding protein A8
chr1_+_153330322	1.61	ENST00000368738.3	S100A9	S100 calcium binding protein A9
chr20_-_43883197	1.60	ENST00000338380.2	SLPI	secretory leukocyte peptidase inhibitor
chr12_+_4385230	1.60	ENST00000536537.1	CCND2	cyclin D2
chr3_+_122044084	1.59	ENST00000264474.3 ENST00000479204.1	CSTA	cystatin A (stefin A)
chr11_-_102651343	1.38	ENST00000279441.4 ENST00000539681.1	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr3_-_111314230	1.32	ENST00000317012.4	ZBED2	zinc finger, BED-type containing 2
chr14_+_75745477	1.30	ENST00000303562.4 ENST00000554617.1 ENST00000554212.1 ENST00000535987.1 ENST00000555242.1	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr9_-_33447584	1.26	ENST00000297991.4	AQP3	aquaporin 3 (Gill blood group)
chr18_+_34124507	1.24	ENST00000591635.1	FHOD3	formin homology 2 domain containing 3
chr6_-_136847610	1.22	ENST00000454590.1 ENST00000432797.2	MAP7	microtubule-associated protein 7
chr6_+_26124373	1.19	ENST00000377791.2 ENST00000602637.1	HIST1H2AC	histone cluster 1, H2ac
chr22_+_29876197	1.18	ENST00000310624.6	NEFH	neurofilament, heavy polypeptide
chr15_-_63674034	1.16	ENST00000344366.3 ENST00000422263.2	CA12	carbonic anhydrase XII
chr1_-_156675535	1.16	ENST00000368221.1	CRABP2	cellular retinoic acid binding protein 2
chr1_+_152881014	1.13	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr12_-_52685312	1.09	ENST00000327741.5	KRT81	keratin 81
chr7_-_41742697	1.05	ENST00000242208.4	INHBA	inhibin, beta A
chr16_+_57406368	1.05	ENST00000006053.6 ENST00000563383.1	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr17_-_39780819	1.04	ENST00000311208.8	KRT17	keratin 17
chr1_-_156675368	1.01	ENST00000368222.3	CRABP2	cellular retinoic acid binding protein 2
chr11_+_62623621	1.00	ENST00000535296.1	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_59043166	1.00	ENST00000371225.2	TACSTD2	tumor-associated calcium signal transducer 2
chr15_-_63674218	0.96	ENST00000178638.3	CA12	carbonic anhydrase XII
chr19_-_6767516	0.93	ENST00000245908.6	SH2D3A	SH2 domain containing 3A
chr1_-_23886285	0.93	ENST00000374561.5	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr17_+_39394250	0.90	ENST00000254072.6	KRTAP9-8	keratin associated protein 9-8
chr9_-_140196703	0.85	ENST00000356628.2	NRARP	NOTCH-regulated ankyrin repeat protein
chr1_-_153013588	0.84	ENST00000360379.3	SPRR2D	small proline-rich protein 2D
chr17_+_39382900	0.77	ENST00000377721.3 ENST00000455970.2	KRTAP9-2	keratin associated protein 9-2
chr11_+_62623544	0.77	ENST00000377890.2 ENST00000377891.2 ENST00000377889.2	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr17_-_48546232	0.75	ENST00000258969.4	CHAD	chondroadherin
chr11_+_62623512	0.75	ENST00000377892.1	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_209825674	0.73	ENST00000367030.3 ENST00000356082.4	LAMB3	laminin, beta 3
chr9_-_124989804	0.73	ENST00000373755.2 ENST00000373754.2	LHX6	LIM homeobox 6
chr1_-_216978709	0.70	ENST00000360012.3	ESRRG	estrogen-related receptor gamma
chr17_+_27573875	0.70	ENST00000225387.3	CRYBA1	crystallin, beta A1
chr16_+_82068830	0.69	ENST00000199936.4	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr1_+_207226574	0.67	ENST00000367080.3 ENST00000367079.2	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr18_+_29598335	0.65	ENST00000217740.3	RNF125	ring finger protein 125, E3 ubiquitin protein ligase
chr1_-_153044083	0.64	ENST00000341611.2	SPRR2B	small proline-rich protein 2B
chr17_-_39661849	0.64	ENST00000246635.3 ENST00000336861.3 ENST00000587544.1 ENST00000587435.1	KRT13	keratin 13
chr8_+_86089460	0.63	ENST00000418930.2	E2F5	E2F transcription factor 5, p130-binding
chr3_+_193853927	0.63	ENST00000232424.3	HES1	hes family bHLH transcription factor 1
chr9_+_130911770	0.62	ENST00000372998.1	LCN2	lipocalin 2
chr15_+_45722727	0.62	ENST00000396650.2 ENST00000558435.1 ENST00000344300.3	C15orf48	chromosome 15 open reading frame 48
chrX_-_133792480	0.62	ENST00000359237.4	PLAC1	placenta-specific 1
chr3_+_142342228	0.60	ENST00000337777.3	PLS1	plastin 1
chr17_-_39023462	0.60	ENST00000251643.4	KRT12	keratin 12
chr11_+_6866883	0.60	ENST00000299454.4 ENST00000379831.2	OR10A5	olfactory receptor, family 10, subfamily A, member 5
chr6_-_27100529	0.59	ENST00000607124.1 ENST00000339812.2 ENST00000541790.1	HIST1H2BJ	histone cluster 1, H2bj
chr19_+_10381769	0.58	ENST00000423829.2 ENST00000588645.1	ICAM1	intercellular adhesion molecule 1
chr6_-_27114577	0.57	ENST00000356950.1 ENST00000396891.4	HIST1H2BK	histone cluster 1, H2bk
chr3_+_127634312	0.56	ENST00000407609.3	KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr5_-_74162605	0.55	ENST00000389156.4 ENST00000510496.1 ENST00000380515.3	FAM169A	family with sequence similarity 169, member A
chrX_+_41548220	0.55	ENST00000378142.4	GPR34	G protein-coupled receptor 34
chr3_+_190333097	0.55	ENST00000412080.1	IL1RAP	interleukin 1 receptor accessory protein
chr4_-_84035868	0.53	ENST00000426923.2 ENST00000509973.1	PLAC8	placenta-specific 8
chr9_+_130911723	0.52	ENST00000277480.2 ENST00000373013.2 ENST00000540948.1	LCN2	lipocalin 2
chr18_-_61329118	0.51	ENST00000332821.8 ENST00000283752.5	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr12_-_48963829	0.51	ENST00000301046.2 ENST00000549817.1	LALBA	lactalbumin, alpha-
chr6_-_26124138	0.51	ENST00000314332.5 ENST00000396984.1	HIST1H2BC	histone cluster 1, H2bc
chr17_-_48546324	0.50	ENST00000508540.1	CHAD	chondroadherin
chr8_+_75896731	0.50	ENST00000262207.4	CRISPLD1	cysteine-rich secretory protein LCCL domain containing 1
chr14_+_71108460	0.48	ENST00000256367.2	TTC9	tetratricopeptide repeat domain 9
chr4_+_76481258	0.47	ENST00000311623.4 ENST00000435974.2	C4orf26	chromosome 4 open reading frame 26
chr4_+_74735102	0.46	ENST00000395761.3	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr9_-_117568365	0.45	ENST00000374045.4	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15
chr12_-_53614155	0.44	ENST00000543726.1	RARG	retinoic acid receptor, gamma
chrX_+_41548259	0.44	ENST00000378138.5	GPR34	G protein-coupled receptor 34
chr22_+_39916558	0.43	ENST00000337304.2 ENST00000396680.1	ATF4	activating transcription factor 4
chr1_+_144339738	0.43	ENST00000538264.1	AL592284.1	Protein LOC642441
chr12_-_53614043	0.43	ENST00000338561.5	RARG	retinoic acid receptor, gamma
chr6_-_26216872	0.42	ENST00000244601.3	HIST1H2BG	histone cluster 1, H2bg
chr14_-_55369525	0.41	ENST00000543643.2 ENST00000536224.2 ENST00000395514.1 ENST00000491895.2	GCH1	GTP cyclohydrolase 1
chr4_-_84035905	0.40	ENST00000311507.4	PLAC8	placenta-specific 8
chr19_+_46732988	0.40	ENST00000437936.1	IGFL1	IGF-like family member 1
chr19_+_1071203	0.40	ENST00000543365.1	HMHA1	histocompatibility (minor) HA-1
chr1_-_6551720	0.39	ENST00000377728.3	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_165555200	0.39	ENST00000479451.1 ENST00000540653.1 ENST00000488954.1 ENST00000264381.3	BCHE	butyrylcholinesterase
chr5_-_57756087	0.38	ENST00000274289.3	PLK2	polo-like kinase 2
chr11_+_68451943	0.38	ENST00000265643.3	GAL	galanin/GMAP prepropeptide
chr17_+_56315787	0.37	ENST00000262290.4 ENST00000421678.2	LPO	lactoperoxidase
chr7_-_25268104	0.36	ENST00000222674.2	NPVF	neuropeptide VF precursor
chr1_+_152647771	0.36	ENST00000417924.2 ENST00000368783.1	LCE2B LCE2C	late cornified envelope 2B late cornified envelope 2C
chr6_-_133035185	0.36	ENST00000367928.4	VNN1	vanin 1
chr4_+_76995855	0.36	ENST00000355810.4 ENST00000349321.3	ART3	ADP-ribosyltransferase 3
chr8_+_1993173	0.36	ENST00000523438.1	MYOM2	myomesin 2
chr1_+_31885963	0.35	ENST00000373709.3	SERINC2	serine incorporator 2
chr6_-_26247259	0.35	ENST00000244537.4	HIST1H4G	histone cluster 1, H4g
chr19_+_1524072	0.35	ENST00000454744.2	PLK5	polo-like kinase 5
chr13_-_103719196	0.35	ENST00000245312.3	SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_116593292	0.34	ENST00000393446.2 ENST00000265437.5 ENST00000393451.3	ST7	suppression of tumorigenicity 7
chr16_+_78056412	0.34	ENST00000299642.4 ENST00000575655.1	CLEC3A	C-type lectin domain family 3, member A
chr3_+_70048881	0.34	ENST00000483525.1	RP11-460N16.1	RP11-460N16.1
chr2_-_75426826	0.34	ENST00000305249.5	TACR1	tachykinin receptor 1
chrX_-_119445306	0.33	ENST00000371369.4 ENST00000440464.1 ENST00000519908.1	TMEM255A	transmembrane protein 255A
chr11_-_67415048	0.33	ENST00000529256.1	ACY3	aspartoacylase (aminocyclase) 3
chr4_+_103422471	0.33	ENST00000226574.4 ENST00000394820.4	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr8_+_1993152	0.33	ENST00000262113.4	MYOM2	myomesin 2
chr17_+_56315936	0.33	ENST00000543544.1	LPO	lactoperoxidase
chr1_-_207095324	0.32	ENST00000530505.1 ENST00000367091.3 ENST00000442471.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr12_+_101988627	0.32	ENST00000547405.1 ENST00000452455.2 ENST00000441232.1 ENST00000360610.2 ENST00000392934.3 ENST00000547509.1 ENST00000361685.2 ENST00000549145.1 ENST00000553190.1	MYBPC1	myosin binding protein C, slow type
chr19_+_13049413	0.32	ENST00000316448.5 ENST00000588454.1	CALR	calreticulin
chr12_+_101988774	0.31	ENST00000545503.2 ENST00000536007.1 ENST00000541119.1 ENST00000361466.2 ENST00000551300.1 ENST00000550270.1	MYBPC1	myosin binding protein C, slow type
chr7_-_72439997	0.31	ENST00000285805.3	TRIM74	tripartite motif containing 74
chr11_-_5248294	0.31	ENST00000335295.4	HBB	hemoglobin, beta
chr10_+_96698406	0.30	ENST00000260682.6	CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
chr6_+_112375462	0.30	ENST00000361714.1	WISP3	WNT1 inducible signaling pathway protein 3
chrX_+_84499081	0.30	ENST00000276123.3	ZNF711	zinc finger protein 711
chr3_-_190167571	0.30	ENST00000354905.2	TMEM207	transmembrane protein 207
chr5_-_53606396	0.29	ENST00000504924.1 ENST00000507646.2 ENST00000502271.1	ARL15	ADP-ribosylation factor-like 15
chr8_-_131028641	0.29	ENST00000523509.1	FAM49B	family with sequence similarity 49, member B
chr17_-_39280419	0.28	ENST00000394014.1	KRTAP4-12	keratin associated protein 4-12
chr7_+_116593433	0.28	ENST00000323984.3 ENST00000393449.1	ST7	suppression of tumorigenicity 7
chr1_+_37940153	0.28	ENST00000373087.6	ZC3H12A	zinc finger CCCH-type containing 12A
chr16_-_3030407	0.28	ENST00000431515.2 ENST00000574385.1 ENST00000576268.1 ENST00000574730.1 ENST00000575632.1 ENST00000573944.1 ENST00000262300.8	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr2_-_208030647	0.28	ENST00000309446.6	KLF7	Kruppel-like factor 7 (ubiquitous)
chr10_-_95209	0.27	ENST00000332708.5 ENST00000309812.4	TUBB8	tubulin, beta 8 class VIII
chr21_+_34398153	0.27	ENST00000382357.3 ENST00000430860.1 ENST00000333337.3	OLIG2	oligodendrocyte lineage transcription factor 2
chr1_-_27481401	0.27	ENST00000263980.3	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr8_-_131028660	0.27	ENST00000401979.2 ENST00000517654.1 ENST00000522361.1 ENST00000518167.1	FAM49B	family with sequence similarity 49, member B
chr16_-_67517716	0.27	ENST00000290953.2	AGRP	agouti related protein homolog (mouse)
chr14_+_65007177	0.26	ENST00000247207.6	HSPA2	heat shock 70kDa protein 2
chr19_-_11591848	0.26	ENST00000359227.3	ELAVL3	ELAV like neuron-specific RNA binding protein 3
chr4_-_110723134	0.26	ENST00000510800.1 ENST00000512148.1	CFI	complement factor I
chr4_-_153601136	0.26	ENST00000504064.1 ENST00000304385.3	TMEM154	transmembrane protein 154
chr20_-_39317868	0.25	ENST00000373313.2	MAFB	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr4_-_110723194	0.25	ENST00000394635.3	CFI	complement factor I
chr9_+_273038	0.25	ENST00000487230.1 ENST00000469391.1	DOCK8	dedicator of cytokinesis 8
chr16_-_3030283	0.25	ENST00000572619.1 ENST00000574415.1 ENST00000440027.2 ENST00000572059.1	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chrX_+_17393543	0.25	ENST00000380060.3	NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr8_+_99956759	0.25	ENST00000522510.1 ENST00000457907.2	OSR2	odd-skipped related transciption factor 2
chr6_-_2903514	0.24	ENST00000380698.4	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr1_-_165324983	0.24	ENST00000367893.4	LMX1A	LIM homeobox transcription factor 1, alpha
chr9_-_69202204	0.24	ENST00000377473.1	FOXD4L6	forkhead box D4-like 6
chr19_-_2050852	0.24	ENST00000541165.1 ENST00000591601.1	MKNK2	MAP kinase interacting serine/threonine kinase 2
chr6_+_26158343	0.24	ENST00000377777.4 ENST00000289316.2	HIST1H2BD	histone cluster 1, H2bd
chr14_-_25045446	0.24	ENST00000216336.2	CTSG	cathepsin G
chr1_+_152658599	0.24	ENST00000368780.3	LCE2B	late cornified envelope 2B
chr6_+_111195973	0.24	ENST00000368885.3 ENST00000368882.3 ENST00000451850.2 ENST00000368877.5	AMD1	adenosylmethionine decarboxylase 1
chr11_+_128634589	0.24	ENST00000281428.8	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr4_-_110723335	0.24	ENST00000394634.2	CFI	complement factor I
chr10_+_5135981	0.24	ENST00000380554.3	AKR1C3	aldo-keto reductase family 1, member C3
chr1_-_935491	0.24	ENST00000304952.6	HES4	hes family bHLH transcription factor 4
chr1_-_8086343	0.24	ENST00000474874.1 ENST00000469499.1 ENST00000377482.5	ERRFI1	ERBB receptor feedback inhibitor 1
chr1_-_54303934	0.24	ENST00000537333.1	NDC1	NDC1 transmembrane nucleoporin
chr7_+_94285637	0.24	ENST00000482108.1 ENST00000488574.1	PEG10	paternally expressed 10
chr1_-_43424500	0.23	ENST00000415851.2 ENST00000426263.3 ENST00000372500.3	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr8_+_50822344	0.23	ENST00000518864.1	SNTG1	syntrophin, gamma 1
chr8_-_23261589	0.23	ENST00000524168.1 ENST00000523833.2 ENST00000519243.1 ENST00000389131.3	LOXL2	lysyl oxidase-like 2
chr3_-_130465604	0.23	ENST00000356763.3	PIK3R4	phosphoinositide-3-kinase, regulatory subunit 4
chr15_-_62457480	0.22	ENST00000380392.3	C2CD4B	C2 calcium-dependent domain containing 4B
chr17_-_38956205	0.22	ENST00000306658.7	KRT28	keratin 28
chr4_-_100356291	0.22	ENST00000476959.1 ENST00000482593.1	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_75024337	0.22	ENST00000450434.1	TRIM73	tripartite motif containing 73
chr1_+_17575584	0.22	ENST00000375460.3	PADI3	peptidyl arginine deiminase, type III
chr21_+_46117087	0.22	ENST00000400365.3	KRTAP10-12	keratin associated protein 10-12
chr1_-_54303949	0.22	ENST00000234725.8	NDC1	NDC1 transmembrane nucleoporin
chr17_+_32612687	0.22	ENST00000305869.3	CCL11	chemokine (C-C motif) ligand 11
chr1_+_6105974	0.22	ENST00000378083.3	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr16_+_29789561	0.21	ENST00000400752.4	ZG16	zymogen granule protein 16
chr10_-_69455873	0.21	ENST00000433211.2	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr1_-_149814478	0.21	ENST00000369161.3	HIST2H2AA3	histone cluster 2, H2aa3
chr1_+_149822620	0.21	ENST00000369159.2	HIST2H2AA4	histone cluster 2, H2aa4
chr3_-_49142504	0.20	ENST00000306125.6 ENST00000420147.2	QARS	glutaminyl-tRNA synthetase
chr3_-_170588163	0.20	ENST00000295830.8	RPL22L1	ribosomal protein L22-like 1
chr10_+_118305435	0.20	ENST00000369221.2	PNLIP	pancreatic lipase
chr1_+_55446465	0.20	ENST00000371268.3	TMEM61	transmembrane protein 61
chr10_-_101190202	0.20	ENST00000543866.1 ENST00000370508.5	GOT1	glutamic-oxaloacetic transaminase 1, soluble
chr7_+_115862858	0.20	ENST00000393481.2	TES	testis derived transcript (3 LIM domains)
chr3_+_148583043	0.20	ENST00000296046.3	CPA3	carboxypeptidase A3 (mast cell)
chr7_+_116593568	0.20	ENST00000446490.1	ST7	suppression of tumorigenicity 7
chr6_+_26217159	0.20	ENST00000303910.2	HIST1H2AE	histone cluster 1, H2ae
chr1_-_153538011	0.20	ENST00000368707.4	S100A2	S100 calcium binding protein A2
chr8_-_16859690	0.19	ENST00000180166.5	FGF20	fibroblast growth factor 20
chr11_+_62432777	0.19	ENST00000532971.1	METTL12	methyltransferase like 12
chr3_-_197025447	0.19	ENST00000346964.2 ENST00000357674.4 ENST00000314062.3 ENST00000448528.2 ENST00000419553.1	DLG1	discs, large homolog 1 (Drosophila)
chr8_-_101734170	0.19	ENST00000522387.1 ENST00000518196.1	PABPC1	poly(A) binding protein, cytoplasmic 1
chr2_-_75426183	0.19	ENST00000409848.3	TACR1	tachykinin receptor 1
chr12_+_25205446	0.19	ENST00000557489.1 ENST00000354454.3 ENST00000536173.1	LRMP	lymphoid-restricted membrane protein
chr12_-_11508520	0.19	ENST00000545626.1 ENST00000500254.2	PRB1	proline-rich protein BstNI subfamily 1
chr6_+_26199737	0.19	ENST00000359985.1	HIST1H2BF	histone cluster 1, H2bf
chr6_-_26197478	0.19	ENST00000356476.2	HIST1H3D	histone cluster 1, H3d
chr3_+_57881966	0.19	ENST00000495364.1	SLMAP	sarcolemma associated protein
chrX_+_84499038	0.19	ENST00000373165.3	ZNF711	zinc finger protein 711
chr14_+_56127989	0.19	ENST00000555573.1	KTN1	kinectin 1 (kinesin receptor)
chr19_+_1026298	0.19	ENST00000263097.4	CNN2	calponin 2
chr9_+_70917276	0.18	ENST00000342833.2	FOXD4L3	forkhead box D4-like 3
chr1_-_54355430	0.18	ENST00000371399.1 ENST00000072644.1 ENST00000412288.1	YIPF1	Yip1 domain family, member 1
chr7_-_30066233	0.18	ENST00000222803.5	FKBP14	FK506 binding protein 14, 22 kDa
chr2_-_208031542	0.18	ENST00000423015.1	KLF7	Kruppel-like factor 7 (ubiquitous)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0002894	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.5	1.6	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.5	2.5	GO:0060356	leucine import(GO:0060356)
0.5	0.5	GO:0060325	head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.4	1.2	GO:0048936	neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
0.4	1.1	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4	2.1	GO:0055064	chloride ion homeostasis(GO:0055064)
0.3	1.0	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3	1.0	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.3	1.2	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.3	1.3	GO:0070295	renal water absorption(GO:0070295)
0.2	0.7	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2	1.1	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2	0.6	GO:2000974	trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.2	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2	2.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	0.4	GO:0014016	neuroblast differentiation(GO:0014016)
0.2	0.5	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.2	0.9	GO:0003430	growth plate cartilage chondrocyte growth(GO:0003430)
0.2	1.0	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2	1.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.2	1.8	GO:0032119	sequestering of zinc ion(GO:0032119)
0.2	0.6	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.2	0.3	GO:0030185	nitric oxide transport(GO:0030185)
0.2	0.5	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1	0.6	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.4	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1	0.4	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.1	0.3	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.1	0.5	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.4	GO:0051795	positive regulation of catagen(GO:0051795)
0.1	0.5	GO:0035106	operant conditioning(GO:0035106)
0.1	0.4	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.1	17.0	GO:0070268	cornification(GO:0070268)
0.1	0.6	GO:1902896	terminal web assembly(GO:1902896)
0.1	0.7	GO:1903301	fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1	0.9	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.5	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.9	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	4.5	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.1	0.3	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1	0.6	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1	0.3	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1	0.2	GO:0036466	synaptic vesicle recycling via endosome(GO:0036466)
0.1	1.2	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.3	GO:0035283	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.1	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1	0.2	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	0.2	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.2	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1	0.4	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.1	1.4	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.4	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1	1.7	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0006106	fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1	0.3	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1	0.1	GO:1900390	positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1	0.2	GO:0048611	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1	0.7	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.6	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	0.2	GO:0016095	polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115)
0.1	0.2	GO:0002728	negative regulation of natural killer cell cytokine production(GO:0002728)
0.1	0.2	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
0.1	0.3	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
0.1	0.7	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.2	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.1	0.3	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
0.1	0.2	GO:0051039	histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1	0.9	GO:0030903	notochord development(GO:0030903)
0.0	0.4	GO:1903764	regulation of potassium ion export across plasma membrane(GO:1903764)
0.0	0.2	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0	0.1	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.0	0.1	GO:1903423	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.9	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.2	GO:0035962	response to interleukin-13(GO:0035962)
0.0	1.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.5	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.3	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.0	0.3	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.0	0.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0	0.2	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.2	GO:0030242	pexophagy(GO:0030242)
0.0	0.4	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0	0.1	GO:0044793	negative regulation by host of viral process(GO:0044793)
0.0	0.1	GO:1990167	protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.2	GO:0070944	neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0	0.2	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0061198	fungiform papilla formation(GO:0061198)
0.0	0.1	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.0	0.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.0	0.2	GO:0001878	response to yeast(GO:0001878)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.5	GO:0019627	urea metabolic process(GO:0019627)
0.0	1.7	GO:0006953	acute-phase response(GO:0006953)
0.0	0.4	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.4	GO:0002347	response to tumor cell(GO:0002347)
0.0	1.6	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.0	GO:1900005	positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0	0.5	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.0	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.1	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.2	GO:0042048	olfactory behavior(GO:0042048)
0.0	0.2	GO:0001771	immunological synapse formation(GO:0001771)
0.0	0.0	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.1	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.0	0.1	GO:0050893	sensory processing(GO:0050893)
0.0	0.9	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.5	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.1	GO:0070970	interleukin-2 secretion(GO:0070970)
0.0	0.1	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.2	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.2	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.1	GO:0019079	viral genome replication(GO:0019079)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.2	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3	1.6	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.2	5.0	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	1.3	GO:0035976	AP1 complex(GO:0035976)
0.2	0.5	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	0.6	GO:1990357	terminal web(GO:1990357)
0.1	7.4	GO:0001533	cornified envelope(GO:0001533)
0.1	8.5	GO:0045095	keratin filament(GO:0045095)
0.1	0.7	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.2	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1	1.1	GO:0005883	neurofilament(GO:0005883)
0.1	0.4	GO:1990037	Lewy body core(GO:1990037)
0.1	0.2	GO:1990031	pinceau fiber(GO:1990031)
0.0	0.1	GO:0097450	astrocyte end-foot(GO:0097450)
0.0	2.0	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.6	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:1990745	EARP complex(GO:1990745)
0.0	0.5	GO:0072687	meiotic spindle(GO:0072687)
0.0	1.3	GO:0032982	myosin filament(GO:0032982)
0.0	3.9	GO:0035580	specific granule lumen(GO:0035580)
0.0	2.8	GO:0000786	nucleosome(GO:0000786)
0.0	0.3	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.0	3.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.3	GO:0043219	lateral loop(GO:0043219)
0.0	0.4	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.3	GO:0031906	late endosome lumen(GO:0031906)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	3.6	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.2	GO:0001939	female pronucleus(GO:0001939)
0.0	0.2	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	1.2	GO:0005865	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.8	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.0	2.2	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.6	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.4	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.3	1.0	GO:0070699	type II activin receptor binding(GO:0070699)
0.3	1.3	GO:0015254	glycerol channel activity(GO:0015254)
0.2	1.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.7	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2	2.5	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.5	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.1	0.5	GO:0004461	lactose synthase activity(GO:0004461)
0.1	6.0	GO:0042056	chemoattractant activity(GO:0042056)
0.1	0.4	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.1	2.1	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1	2.1	GO:0019841	retinol binding(GO:0019841)
0.1	0.7	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	0.5	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.1	0.5	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.7	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.4	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.1	0.4	GO:0004966	galanin receptor activity(GO:0004966)
0.1	0.6	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.4	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.9	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0080130	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	0.3	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.2	GO:0017130	poly(C) RNA binding(GO:0017130)
0.1	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
0.0	1.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.4	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0070697	activin receptor binding(GO:0070697)
0.0	0.4	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	1.0	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.3	GO:0001849	complement component C1q binding(GO:0001849)
0.0	6.4	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	1.1	GO:0019210	protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0	0.3	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.2	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.1	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.0	0.2	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	1.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	6.0	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.7	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.5	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.9	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.1	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0	0.1	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.0	0.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0	2.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	1.7	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	0.2	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0010857	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0	0.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.3	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.0	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.5	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	7.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	1.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	2.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.9	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	1.0	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	2.1	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	3.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	2.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription