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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TBX20

Z-value: 0.67

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Transcription factors associated with TBX20

Gene Symbol Gene ID Gene Info
ENSG00000164532.10 TBX20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX20hg19_v2_chr7_-_35293740_35293758-0.432.9e-01Click!

Activity profile of TBX20 motif

Sorted Z-values of TBX20 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX20

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_57662419 4.38 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr17_-_3599492 0.99 ENST00000435558.1
ENST00000345901.3
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr6_-_136788001 0.99 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr17_-_3599327 0.98 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr2_+_85360499 0.88 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr17_-_3599696 0.80 ENST00000225328.5
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr6_-_2842087 0.67 ENST00000537185.1
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr6_-_2842219 0.55 ENST00000380739.5
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr7_-_139763521 0.46 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr2_+_207630081 0.31 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr3_+_142315225 0.31 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr10_-_131762105 0.23 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr2_+_61108650 0.23 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_-_158300747 0.22 ENST00000451207.1
CD1B
CD1b molecule
chr5_+_135394840 0.22 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr2_+_61108771 0.21 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_+_40428647 0.21 ENST00000301825.3
ENST00000439533.1
ENST00000456402.1
ENTPD3
ectonucleoside triphosphate diphosphohydrolase 3
chr5_+_161494521 0.21 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_+_176972000 0.18 ENST00000249504.5
HOXD11
homeobox D11
chr15_-_22448819 0.16 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr3_-_139396853 0.16 ENST00000406164.1
ENST00000406824.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr1_+_22964073 0.14 ENST00000402322.1
C1QA
complement component 1, q subcomponent, A chain
chr3_-_139396801 0.14 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr3_-_50396978 0.13 ENST00000266025.3
TMEM115
transmembrane protein 115
chr11_+_6281036 0.13 ENST00000532715.1
ENST00000525014.1
ENST00000531712.1
ENST00000525462.1
CCKBR
cholecystokinin B receptor
chr1_+_43824669 0.12 ENST00000372462.1
CDC20
cell division cycle 20
chr10_+_114135004 0.12 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_-_11865982 0.12 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_+_31805131 0.11 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr6_-_107077347 0.10 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chrX_+_7810303 0.09 ENST00000381059.3
ENST00000341408.4
VCX
variable charge, X-linked
chr1_-_11118896 0.09 ENST00000465788.1
SRM
spermidine synthase
chr10_+_114135952 0.09 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_-_219134822 0.09 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr7_-_142099977 0.09 ENST00000390359.3
TRBV7-8
T cell receptor beta variable 7-8
chrX_-_52386980 0.08 ENST00000330906.4
XAGE2
X antigen family, member 2
chr14_-_106453155 0.08 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr1_+_87797351 0.08 ENST00000370542.1
LMO4
LIM domain only 4
chr19_+_44331493 0.07 ENST00000588797.1
ZNF283
zinc finger protein 283
chrX_+_52112158 0.07 ENST00000286049.2
XAGE2B
X antigen family, member 2B
chr12_-_23737534 0.06 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr10_+_88414298 0.05 ENST00000372071.2
OPN4
opsin 4
chr10_+_88414338 0.05 ENST00000241891.5
ENST00000443292.1
OPN4
opsin 4
chrX_+_67913471 0.04 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr1_+_147013182 0.04 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr3_-_131221790 0.03 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
MRPL3
mitochondrial ribosomal protein L3
chr1_-_17380630 0.02 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr15_-_38519066 0.02 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr11_-_89540388 0.02 ENST00000532501.2
TRIM49
tripartite motif containing 49
chr9_-_72287191 0.01 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators