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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TBX21_TBR1

Z-value: 0.90

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Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
TBX21
ENSG00000073861.2 TBX21
TBR1
ENSG00000136535.10 TBR1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX21hg19_v2_chr17_+_45810594_458106100.874.6e-03Click!
TBR1hg19_v2_chr2_+_162272605_162272753-0.639.8e-02Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_12862604 2.18 ENST00000553030.1
 BEST2
 bestrophin 2
chr4_+_124317940 1.69 ENST00000505319.1
ENST00000339241.1
 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_-_100712352 1.59 ENST00000471714.1
ENST00000284322.5
 ABI3BP
 ABI family, member 3 (NESH) binding protein
chr19_+_12862486 1.39 ENST00000549706.1
 BEST2
 bestrophin 2
chr1_-_85930246 1.36 ENST00000426972.3
 DDAH1
 dimethylarginine dimethylaminohydrolase 1
chr3_-_66551351 1.12 ENST00000273261.3
 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
chr4_-_89619386 1.10 ENST00000323061.5
 NAP1L5
 nucleosome assembly protein 1-like 5
chr3_-_66551397 1.09 ENST00000383703.3
 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
chr2_-_175870085 1.06 ENST00000409156.3
 CHN1
 chimerin 1
chr2_-_175869936 1.05 ENST00000409900.3
 CHN1
 chimerin 1
chr12_-_91576561 0.99 ENST00000547568.2
ENST00000552962.1
 DCN
 decorin
chr9_+_17134980 0.95 ENST00000380647.3
 CNTLN
 centlein, centrosomal protein
chr12_-_91576429 0.92 ENST00000552145.1
ENST00000546745.1
 DCN
 decorin
chr2_-_200322723 0.86 ENST00000417098.1
 SATB2
 SATB homeobox 2
chr10_+_31608054 0.80 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
 ZEB1
 zinc finger E-box binding homeobox 1
chr1_+_38022513 0.78 ENST00000296218.7
 DNALI1
 dynein, axonemal, light intermediate chain 1
chr6_-_46459675 0.73 ENST00000306764.7
 RCAN2
 regulator of calcineurin 2
chr12_+_65672702 0.72 ENST00000538045.1
ENST00000535239.1
 MSRB3
 methionine sulfoxide reductase B3
chr1_-_163172625 0.69 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
 RGS5
 regulator of G-protein signaling 5
chr5_+_140571902 0.68 ENST00000239446.4
 PCDHB10
 protocadherin beta 10
chr14_+_95078714 0.68 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
 SERPINA3
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr22_+_31003190 0.67 ENST00000407817.3
 TCN2
 transcobalamin II
chr22_+_31003133 0.67 ENST00000405742.3
 TCN2
 transcobalamin II
chr16_+_53133070 0.66 ENST00000565832.1
 CHD9
 chromodomain helicase DNA binding protein 9
chr9_+_90112117 0.61 ENST00000358077.5
 DAPK1
 death-associated protein kinase 1
chr13_+_76378305 0.60 ENST00000526371.1
ENST00000526528.1
 LMO7
 LIM domain 7
chr15_+_41913690 0.59 ENST00000563576.1
 MGA
 MGA, MAX dimerization protein
chr11_-_82782861 0.57 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
 RAB30
 RAB30, member RAS oncogene family
chr12_-_90024360 0.54 ENST00000393164.2
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr3_-_120170052 0.54 ENST00000295633.3
 FSTL1
 follistatin-like 1
chr5_-_147286065 0.53 ENST00000318315.4
ENST00000515291.1
 C5orf46
 chromosome 5 open reading frame 46
chr1_+_38022572 0.52 ENST00000541606.1
 DNALI1
 dynein, axonemal, light intermediate chain 1
chr3_-_179169330 0.51 ENST00000232564.3
 GNB4
 guanine nucleotide binding protein (G protein), beta polypeptide 4
chr13_+_76378357 0.50 ENST00000489941.2
ENST00000525373.1
 LMO7
 LIM domain 7
chr22_+_35776828 0.50 ENST00000216117.8
 HMOX1
 heme oxygenase (decycling) 1
chr2_-_79313973 0.48 ENST00000454188.1
 REG1B
 regenerating islet-derived 1 beta
chr12_-_91348949 0.47 ENST00000358859.2
 CCER1
 coiled-coil glutamate-rich protein 1
chr9_+_134378289 0.46 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
 POMT1
 protein-O-mannosyltransferase 1
chr2_+_217498105 0.46 ENST00000233809.4
 IGFBP2
 insulin-like growth factor binding protein 2, 36kDa
chr12_+_65672423 0.45 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
 MSRB3
 methionine sulfoxide reductase B3
chr14_+_21467414 0.44 ENST00000554422.1
ENST00000298681.4
 SLC39A2
 solute carrier family 39 (zinc transporter), member 2
chr1_+_201708992 0.44 ENST00000367295.1
 NAV1
 neuron navigator 1
chr6_-_153452356 0.44 ENST00000206262.1
 RGS17
 regulator of G-protein signaling 17
chr15_-_83316087 0.43 ENST00000568757.1
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr11_+_61447845 0.43 ENST00000257215.5
 DAGLA
 diacylglycerol lipase, alpha
chr1_-_46598284 0.43 ENST00000423209.1
ENST00000262741.5
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr1_-_46598371 0.43 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr12_-_96184533 0.43 ENST00000343702.4
ENST00000344911.4
 NTN4
 netrin 4
chr17_-_8066843 0.42 ENST00000404970.3
 VAMP2
 vesicle-associated membrane protein 2 (synaptobrevin 2)
chr14_-_65569244 0.41 ENST00000557277.1
ENST00000556892.1
 MAX
 MYC associated factor X
chr11_-_82782952 0.40 ENST00000534141.1
 RAB30
 RAB30, member RAS oncogene family
chr9_-_35815013 0.40 ENST00000259667.5
 HINT2
 histidine triad nucleotide binding protein 2
chr1_+_26146397 0.39 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
 MTFR1L
 mitochondrial fission regulator 1-like
chr6_+_132873832 0.39 ENST00000275200.1
 TAAR8
 trace amine associated receptor 8
chr17_-_15165854 0.39 ENST00000395936.1
ENST00000395938.2
 PMP22
 peripheral myelin protein 22
chr15_-_83316254 0.39 ENST00000567678.1
ENST00000450751.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr8_-_27457494 0.38 ENST00000521770.1
 CLU
 clusterin
chr5_+_54320078 0.38 ENST00000231009.2
 GZMK
 granzyme K (granzyme 3; tryptase II)
chr4_-_186732048 0.38 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
 SORBS2
 sorbin and SH3 domain containing 2
chr15_-_90294523 0.38 ENST00000300057.4
 MESP1
 mesoderm posterior 1 homolog (mouse)
chr6_+_45390222 0.37 ENST00000359524.5
 RUNX2
 runt-related transcription factor 2
chr1_+_26146674 0.37 ENST00000525713.1
ENST00000374301.3
 MTFR1L
 mitochondrial fission regulator 1-like
chr12_+_57853918 0.36 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
 GLI1
 GLI family zinc finger 1
chr2_-_157189180 0.36 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr12_-_56120838 0.35 ENST00000548160.1
 CD63
 CD63 molecule
chr15_+_44119159 0.35 ENST00000263795.6
ENST00000381246.2
ENST00000452115.1
 WDR76
 WD repeat domain 76
chr6_-_154751629 0.35 ENST00000424998.1
 CNKSR3
 CNKSR family member 3
chr11_+_65266507 0.34 ENST00000544868.1
 MALAT1
 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr10_+_90660832 0.34 ENST00000371924.1
 STAMBPL1
 STAM binding protein-like 1
chr6_+_45389893 0.33 ENST00000371432.3
 RUNX2
 runt-related transcription factor 2
chr19_-_44405941 0.33 ENST00000587128.1
 RP11-15A1.3
 RP11-15A1.3
chr4_+_160188889 0.33 ENST00000264431.4
 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_93107443 0.32 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_68628543 0.32 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
 CCDC125
 coiled-coil domain containing 125
chr17_-_76356148 0.32 ENST00000587578.1
ENST00000330871.2
 SOCS3
 suppressor of cytokine signaling 3
chr15_+_60296421 0.32 ENST00000396057.4
 FOXB1
 forkhead box B1
chr5_-_131132614 0.32 ENST00000307968.7
ENST00000307954.8
 FNIP1
 folliculin interacting protein 1
chr19_-_36236292 0.30 ENST00000378975.3
ENST00000412391.2
ENST00000292879.5
 U2AF1L4
 U2 small nuclear RNA auxiliary factor 1-like 4
chr6_+_39760129 0.30 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr2_-_152146385 0.30 ENST00000414946.1
ENST00000243346.5
 NMI
 N-myc (and STAT) interactor
chr2_+_162087577 0.30 ENST00000439442.1
 TANK
 TRAF family member-associated NFKB activator
chr13_+_114238997 0.29 ENST00000538138.1
ENST00000375370.5
 TFDP1
 transcription factor Dp-1
chr19_+_46367518 0.29 ENST00000302177.2
 FOXA3
 forkhead box A3
chrX_+_51636629 0.29 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
 MAGED1
 melanoma antigen family D, 1
chr1_+_144989309 0.29 ENST00000596396.1
 AL590452.1
 Uncharacterized protein
chr10_+_45406627 0.29 ENST00000389583.4
 TMEM72
 transmembrane protein 72
chr1_+_145507587 0.28 ENST00000330165.8
ENST00000369307.3
 RBM8A
 RNA binding motif protein 8A
chr9_+_124048864 0.28 ENST00000545652.1
 GSN
 gelsolin
chr19_-_50529193 0.28 ENST00000596445.1
ENST00000599538.1
 VRK3
 vaccinia related kinase 3
chr7_-_138386097 0.28 ENST00000421622.1
 SVOPL
 SVOP-like
chr1_-_1009683 0.28 ENST00000453464.2
 RNF223
 ring finger protein 223
chr1_-_28969517 0.27 ENST00000263974.4
ENST00000373824.4
 TAF12
 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr8_+_22428457 0.27 ENST00000517962.1
 SORBS3
 sorbin and SH3 domain containing 3
chr22_-_31688381 0.26 ENST00000487265.2
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chrX_-_140271249 0.26 ENST00000370526.2
 LDOC1
 leucine zipper, down-regulated in cancer 1
chr14_-_45603657 0.25 ENST00000396062.3
 FKBP3
 FK506 binding protein 3, 25kDa
chr17_+_58755184 0.25 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
 BCAS3
 breast carcinoma amplified sequence 3
chr3_-_49466686 0.25 ENST00000273598.3
ENST00000436744.2
 NICN1
 nicolin 1
chr7_-_120497178 0.25 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
 TSPAN12
 tetraspanin 12
chr2_+_201994042 0.25 ENST00000417748.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr1_+_39456895 0.24 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
 AKIRIN1
 akirin 1
chr16_+_12995468 0.24 ENST00000424107.3
ENST00000558583.1
ENST00000558318.1
 SHISA9
 shisa family member 9
chr22_-_43042955 0.24 ENST00000402438.1
 CYB5R3
 cytochrome b5 reductase 3
chr10_+_94451574 0.24 ENST00000492654.2
 HHEX
 hematopoietically expressed homeobox
chr9_+_34990219 0.23 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
 DNAJB5
 DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_+_26585686 0.23 ENST00000505206.1
ENST00000511789.1
 TBC1D19
 TBC1 domain family, member 19
chr17_-_26662464 0.23 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr17_-_26662440 0.23 ENST00000578122.1
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr19_-_7990991 0.23 ENST00000318978.4
 CTXN1
 cortexin 1
chr4_-_8073705 0.23 ENST00000514025.1
 ABLIM2
 actin binding LIM protein family, member 2
chr4_+_166300084 0.22 ENST00000402744.4
 CPE
 carboxypeptidase E
chr22_+_40441456 0.22 ENST00000402203.1
 TNRC6B
 trinucleotide repeat containing 6B
chr8_-_93107696 0.22 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_84937314 0.22 ENST00000257766.4
ENST00000403245.3
 KIAA1009
 KIAA1009
chr16_+_27413483 0.22 ENST00000337929.3
ENST00000564089.1
 IL21R
 interleukin 21 receptor
chr2_-_3584430 0.22 ENST00000438482.1
ENST00000422961.1
 AC108488.4
 AC108488.4
chr1_+_174843548 0.22 ENST00000478442.1
ENST00000465412.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr11_+_73358594 0.21 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
 PLEKHB1
 pleckstrin homology domain containing, family B (evectins) member 1
chr2_+_219247021 0.21 ENST00000539932.1
 SLC11A1
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chrX_+_102862834 0.21 ENST00000372627.5
ENST00000243286.3
 TCEAL3
 transcription elongation factor A (SII)-like 3
chr6_+_131894284 0.21 ENST00000368087.3
ENST00000356962.2
 ARG1
 arginase 1
chr9_+_34329493 0.21 ENST00000379158.2
ENST00000346365.4
ENST00000379155.5
 NUDT2
 nudix (nucleoside diphosphate linked moiety X)-type motif 2
chrX_-_69509738 0.21 ENST00000374454.1
ENST00000239666.4
 PDZD11
 PDZ domain containing 11
chr7_-_76255444 0.21 ENST00000454397.1
 POMZP3
 POM121 and ZP3 fusion
chr8_-_6914251 0.21 ENST00000330590.2
 DEFA5
 defensin, alpha 5, Paneth cell-specific
chr7_-_138363824 0.21 ENST00000419765.3
 SVOPL
 SVOP-like
chr10_+_118305435 0.21 ENST00000369221.2
 PNLIP
 pancreatic lipase
chr20_+_18125727 0.21 ENST00000489634.2
 CSRP2BP
 CSRP2 binding protein
chr1_+_213123976 0.20 ENST00000366965.2
ENST00000366967.2
 VASH2
 vasohibin 2
chr13_+_42031679 0.20 ENST00000379359.3
 RGCC
 regulator of cell cycle
chr5_+_94727048 0.20 ENST00000283357.5
 FAM81B
 family with sequence similarity 81, member B
chr17_+_9066252 0.20 ENST00000436734.1
 NTN1
 netrin 1
chr3_-_146213722 0.20 ENST00000336685.2
ENST00000489015.1
 PLSCR2
 phospholipid scramblase 2
chr9_+_125273081 0.20 ENST00000335302.5
 OR1J2
 olfactory receptor, family 1, subfamily J, member 2
chr5_+_137419581 0.20 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
 WNT8A
 wingless-type MMTV integration site family, member 8A
chr2_-_166060571 0.19 ENST00000360093.3
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr1_-_113247543 0.19 ENST00000414971.1
ENST00000534717.1
 RHOC
 ras homolog family member C
chr17_-_18585131 0.19 ENST00000443457.1
ENST00000583002.1
 ZNF286B
 zinc finger protein 286B
chr8_-_42623924 0.19 ENST00000276410.2
 CHRNA6
 cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr9_+_17135016 0.19 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
 CNTLN
 centlein, centrosomal protein
chr5_+_6448736 0.19 ENST00000399816.3
 UBE2QL1
 ubiquitin-conjugating enzyme E2Q family-like 1
chr3_+_42977846 0.19 ENST00000383748.4
 KRBOX1
 KRAB box domain containing 1
chr4_+_100495864 0.19 ENST00000265517.5
ENST00000422897.2
 MTTP
 microsomal triglyceride transfer protein
chr8_+_38586068 0.19 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr1_+_156105878 0.19 ENST00000508500.1
 LMNA
 lamin A/C
chr16_+_21716284 0.19 ENST00000388957.3
 OTOA
 otoancorin
chr2_-_61697862 0.19 ENST00000398571.2
 USP34
 ubiquitin specific peptidase 34
chr9_+_33750667 0.19 ENST00000457896.1
ENST00000342836.4
ENST00000429677.3
 PRSS3
 protease, serine, 3
chr17_+_75084717 0.19 ENST00000561721.2
ENST00000589827.1
ENST00000392476.2
 SEC14L1
 SEC14-like 1 (S. cerevisiae)
chr12_+_12938541 0.18 ENST00000356591.4
 APOLD1
 apolipoprotein L domain containing 1
chr9_+_33750515 0.18 ENST00000361005.5
 PRSS3
 protease, serine, 3
chr2_+_204192942 0.18 ENST00000295851.5
ENST00000261017.5
 ABI2
 abl-interactor 2
chr8_-_42623747 0.18 ENST00000534622.1
 CHRNA6
 cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr2_-_166060552 0.18 ENST00000283254.7
ENST00000453007.1
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit
chr7_-_14942283 0.17 ENST00000402815.1
 DGKB
 diacylglycerol kinase, beta 90kDa
chr13_+_53602894 0.17 ENST00000219022.2
 OLFM4
 olfactomedin 4
chr17_+_15603447 0.17 ENST00000395893.2
 ZNF286A
 Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr6_+_160221293 0.17 ENST00000610273.1
ENST00000392167.3
 PNLDC1
 poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr12_-_110511424 0.17 ENST00000548191.1
 C12orf76
 chromosome 12 open reading frame 76
chr17_-_1553346 0.17 ENST00000301336.6
 RILP
 Rab interacting lysosomal protein
chr2_+_85646054 0.17 ENST00000389938.2
 SH2D6
 SH2 domain containing 6
chr6_-_33679452 0.17 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
 UQCC2
 ubiquinol-cytochrome c reductase complex assembly factor 2
chr22_-_31688431 0.17 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr11_+_45907177 0.17 ENST00000241014.2
 MAPK8IP1
 mitogen-activated protein kinase 8 interacting protein 1
chr8_+_38585704 0.17 ENST00000519416.1
ENST00000520615.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr12_-_76879852 0.17 ENST00000548341.1
 OSBPL8
 oxysterol binding protein-like 8
chr11_-_64052111 0.16 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
 BAD
 BCL2-associated agonist of cell death
chr14_+_77582905 0.16 ENST00000557408.1
 TMEM63C
 transmembrane protein 63C
chr3_+_38035610 0.16 ENST00000465644.1
 VILL
 villin-like
chr22_-_43042968 0.16 ENST00000407623.3
ENST00000396303.3
ENST00000438270.1
 CYB5R3
 cytochrome b5 reductase 3
chr9_-_132805430 0.16 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
 FNBP1
 formin binding protein 1
chr16_+_69221028 0.16 ENST00000336278.4
 SNTB2
 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr9_+_35829208 0.15 ENST00000439587.2
ENST00000377991.4
 TMEM8B
 transmembrane protein 8B
chr10_-_23003460 0.15 ENST00000376573.4
 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chrX_+_77166172 0.15 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr5_-_176433350 0.15 ENST00000377227.4
ENST00000377219.2
 UIMC1
 ubiquitin interaction motif containing 1
chr13_+_46276441 0.15 ENST00000310521.1
ENST00000533564.1
 SPERT
 spermatid associated
chr12_-_56120865 0.15 ENST00000548898.1
ENST00000552067.1
 CD63
 CD63 molecule
chr6_+_168418553 0.15 ENST00000354419.2
ENST00000351261.3
 KIF25
 kinesin family member 25
chr11_+_18477369 0.15 ENST00000396213.3
ENST00000280706.2
 LDHAL6A
 lactate dehydrogenase A-like 6A
chr17_-_56609302 0.15 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
 SEPT4
 septin 4
chr1_-_150780757 0.15 ENST00000271651.3
 CTSK
 cathepsin K
chr11_-_114271139 0.15 ENST00000325636.4
 C11orf71
 chromosome 11 open reading frame 71
chr8_-_72268889 0.15 ENST00000388742.4
 EYA1
 eyes absent homolog 1 (Drosophila)
chr11_-_236326 0.15 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
 SIRT3
 sirtuin 3
chr11_-_6440624 0.14 ENST00000311051.3
 APBB1
 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chrX_-_19689106 0.14 ENST00000379716.1
 SH3KBP1
 SH3-domain kinase binding protein 1
chr3_-_100712292 0.14 ENST00000495063.1
ENST00000530539.1
 ABI3BP
 ABI family, member 3 (NESH) binding protein
chr11_+_122709200 0.14 ENST00000227348.4
 CRTAM
 cytotoxic and regulatory T cell molecule
chr11_+_66278080 0.14 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
 BBS1
 Bardet-Biedl syndrome 1
chr6_-_30585009 0.14 ENST00000376511.2
 PPP1R10
 protein phosphatase 1, regulatory subunit 10
chr5_-_131132658 0.14 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
 CTC-432M15.3
FNIP1
 Folliculin-interacting protein 1
folliculin interacting protein 1
chrX_+_102631844 0.14 ENST00000372634.1
ENST00000299872.7
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr11_+_55653396 0.14 ENST00000244891.3
 TRIM51
 tripartite motif-containing 51
chr16_-_30546141 0.13 ENST00000535210.1
ENST00000395094.3
 ZNF747
 zinc finger protein 747
chr20_+_36661910 0.13 ENST00000373433.4
 RPRD1B
 regulation of nuclear pre-mRNA domain containing 1B
chr1_+_89829610 0.13 ENST00000370456.4
ENST00000535065.1
 GBP6
 guanylate binding protein family, member 6
chr7_-_99766191 0.13 ENST00000423751.1
ENST00000360039.4
 GAL3ST4
 galactose-3-O-sulfotransferase 4
chr1_-_241799232 0.13 ENST00000366553.1
 CHML
 choroideremia-like (Rab escort protein 2)
chr3_+_14058794 0.13 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
 TPRXL
 tetra-peptide repeat homeobox-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.4 2.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.5 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 1.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.4 GO:0060913 cardiac cell fate determination(GO:0060913) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0061010 gall bladder development(GO:0061010)
0.1 0.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 1.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 1.2 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.3 GO:0055073 cadmium ion homeostasis(GO:0055073) divalent metal ion export(GO:0070839)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.4 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.4 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.5 GO:1901660 cellular response to corticosterone stimulus(GO:0071386) calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 1.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.7 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.2 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 2.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.0 0.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 1.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0003068 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 3.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0002860 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.0 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0002254 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.0 GO:0033212 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.1 GO:0009407 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.0 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.3 GO:1900120 regulation of receptor binding(GO:1900120)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 3.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 1.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.0 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 1.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.3 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 0.3 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 3.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 2.2 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation