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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TFAP2E

Z-value: 0.34

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Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
ENSG00000116819.6 TFAP2E

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Ehg19_v2_chr1_+_36038971_36038971-0.019.9e-01Click!

Activity profile of TFAP2E motif

Sorted Z-values of TFAP2E motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_43969796 0.21 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr19_-_54676846 0.14 ENST00000301187.4
TMC4
transmembrane channel-like 4
chr19_-_54676884 0.13 ENST00000376591.4
TMC4
transmembrane channel-like 4
chr17_+_74070853 0.09 ENST00000329003.3
GALR2
galanin receptor 2
chr1_+_214163033 0.09 ENST00000607425.1
PROX1
prospero homeobox 1
chr1_+_233749739 0.09 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr1_-_32801825 0.09 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr20_+_55205825 0.08 ENST00000544508.1
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr12_+_72666407 0.07 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr19_+_45504688 0.07 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr4_+_154387480 0.07 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr3_-_55521323 0.07 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr4_+_75480629 0.06 ENST00000380846.3
AREGB
amphiregulin B
chr11_-_118305921 0.06 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr11_-_66056478 0.05 ENST00000431556.2
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr22_+_31608219 0.05 ENST00000406516.1
ENST00000444929.2
ENST00000331728.4
LIMK2
LIM domain kinase 2
chr17_+_40932610 0.05 ENST00000246914.5
WNK4
WNK lysine deficient protein kinase 4
chr17_-_39769005 0.05 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chrX_+_128872998 0.05 ENST00000371106.3
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr22_+_31644388 0.04 ENST00000333611.4
ENST00000340552.4
LIMK2
LIM domain kinase 2
chr6_+_7108210 0.04 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr4_-_101439242 0.04 ENST00000296420.4
EMCN
endomucin
chr6_+_13272904 0.04 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr6_+_7107999 0.04 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr15_+_23810853 0.04 ENST00000568252.1
MKRN3
makorin ring finger protein 3
chr12_+_57984965 0.04 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr15_+_27112194 0.04 ENST00000555182.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr1_+_17634689 0.04 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chrX_+_115567767 0.04 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr1_+_901847 0.04 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr11_-_113345995 0.03 ENST00000355319.2
ENST00000542616.1
DRD2
dopamine receptor D2
chr3_+_4535025 0.03 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr3_+_52813932 0.03 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr17_-_42992856 0.03 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr11_-_66056596 0.03 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr15_+_27112380 0.03 ENST00000554596.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr17_+_48423453 0.03 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr6_+_99282570 0.03 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr22_+_22676808 0.03 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr6_+_42531798 0.03 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr11_-_47870019 0.03 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr15_+_27112058 0.03 ENST00000355395.5
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr11_-_65325430 0.03 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr19_+_50936142 0.03 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr4_-_82393009 0.03 ENST00000436139.2
RASGEF1B
RasGEF domain family, member 1B
chr11_-_47869865 0.03 ENST00000530326.1
ENST00000532747.1
NUP160
nucleoporin 160kDa
chrX_+_152783131 0.02 ENST00000349466.2
ENST00000370186.1
ATP2B3
ATPase, Ca++ transporting, plasma membrane 3
chr6_+_7107830 0.02 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr15_+_27112251 0.02 ENST00000400081.3
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chrX_+_49028265 0.02 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr3_+_4535155 0.02 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr19_-_39264072 0.02 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr6_+_150070831 0.02 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr12_-_75784669 0.02 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr12_+_75784850 0.02 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr20_+_58508817 0.02 ENST00000358293.3
FAM217B
family with sequence similarity 217, member B
chr11_+_64009072 0.02 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr19_+_36195429 0.02 ENST00000392197.2
ZBTB32
zinc finger and BTB domain containing 32
chr7_-_140624499 0.02 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr5_-_179499108 0.02 ENST00000521389.1
RNF130
ring finger protein 130
chr3_+_49591881 0.02 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr5_-_179499086 0.02 ENST00000261947.4
RNF130
ring finger protein 130
chrX_-_124097620 0.02 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr2_+_75061108 0.02 ENST00000290573.2
HK2
hexokinase 2
chr3_+_155860751 0.02 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr11_+_63974135 0.02 ENST00000544997.1
ENST00000345728.5
ENST00000279227.5
FERMT3
fermitin family member 3
chr4_-_85419603 0.02 ENST00000295886.4
NKX6-1
NK6 homeobox 1
chr2_+_241375069 0.02 ENST00000264039.2
GPC1
glypican 1
chr1_-_114355083 0.02 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr14_-_25519095 0.02 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr9_+_35605274 0.02 ENST00000336395.5
TESK1
testis-specific kinase 1
chr15_-_65503801 0.02 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr11_-_47870091 0.02 ENST00000526870.1
NUP160
nucleoporin 160kDa
chr19_+_4969116 0.02 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
KDM4B
lysine (K)-specific demethylase 4B
chr14_+_21214039 0.02 ENST00000326842.2
EDDM3A
epididymal protein 3A
chr6_+_150070857 0.02 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_-_231175964 0.01 ENST00000366654.4
FAM89A
family with sequence similarity 89, member A
chr1_-_11866034 0.01 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr15_+_27112296 0.01 ENST00000554038.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr1_-_154531095 0.01 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr2_-_241831424 0.01 ENST00000402775.2
ENST00000307486.8
C2orf54
chromosome 2 open reading frame 54
chr9_+_128024067 0.01 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GAPVD1
GTPase activating protein and VPS9 domains 1
chr17_+_37824700 0.01 ENST00000581428.1
PNMT
phenylethanolamine N-methyltransferase
chr15_+_77287426 0.01 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr20_-_25371412 0.01 ENST00000339157.5
ENST00000376542.3
ABHD12
abhydrolase domain containing 12
chr20_-_13619550 0.01 ENST00000455532.1
ENST00000544472.1
ENST00000539805.1
ENST00000337743.4
TASP1
taspase, threonine aspartase, 1
chr14_-_25519317 0.01 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr3_-_136471204 0.01 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr8_+_17780346 0.01 ENST00000325083.8
PCM1
pericentriolar material 1
chr9_+_19230433 0.01 ENST00000434457.2
ENST00000602925.1
DENND4C
DENN/MADD domain containing 4C
chr2_+_38893047 0.01 ENST00000272252.5
GALM
galactose mutarotase (aldose 1-epimerase)
chr10_-_112678976 0.01 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr1_+_182584314 0.01 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr17_-_47755338 0.01 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chr1_-_11865982 0.01 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr17_+_3627185 0.01 ENST00000325418.4
GSG2
germ cell associated 2 (haspin)
chr5_-_179498703 0.01 ENST00000522208.2
RNF130
ring finger protein 130
chr8_+_17780483 0.01 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
PCM1
pericentriolar material 1
chr5_+_133984462 0.01 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr11_+_66045634 0.01 ENST00000528852.1
ENST00000311445.6
CNIH2
cornichon family AMPA receptor auxiliary protein 2
chr13_-_27334879 0.01 ENST00000405846.3
GPR12
G protein-coupled receptor 12
chr7_-_129251459 0.01 ENST00000608694.1
RP11-448A19.1
RP11-448A19.1
chr17_+_37824217 0.01 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr4_-_101439148 0.01 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN
endomucin
chr17_+_37824411 0.01 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr3_+_171757346 0.01 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
FNDC3B
fibronectin type III domain containing 3B
chr1_+_104068312 0.00 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr10_+_99894399 0.00 ENST00000298999.3
ENST00000314594.5
R3HCC1L
R3H domain and coiled-coil containing 1-like
chr19_-_11039261 0.00 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
YIPF2
Yip1 domain family, member 2
chr9_+_136501478 0.00 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr10_-_108924284 0.00 ENST00000344440.6
ENST00000263054.6
SORCS1
sortilin-related VPS10 domain containing receptor 1
chr11_-_82612727 0.00 ENST00000531128.1
ENST00000535099.1
ENST00000527444.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr1_+_76540386 0.00 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr1_+_9599540 0.00 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr11_+_118478313 0.00 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr19_+_13229126 0.00 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr10_-_98273668 0.00 ENST00000357947.3
TLL2
tolloid-like 2
chr1_+_104068562 0.00 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr22_+_35653445 0.00 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4
HMG box domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0061346 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)