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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TFAP4_MSC

Z-value: 0.85

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Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
TFAP4
ENSG00000090447.7 TFAP4
MSC
ENSG00000178860.8 MSC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSChg19_v2_chr8_-_72756667_727567360.849.0e-03Click!
TFAP4hg19_v2_chr16_-_4323015_4323076-0.658.0e-02Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_225811747 1.53 ENST00000409592.3
 DOCK10
 dedicator of cytokinesis 10
chr6_-_31697255 1.52 ENST00000436437.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr13_+_102104980 1.51 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr17_-_53800217 1.36 ENST00000424486.2
 TMEM100
 transmembrane protein 100
chr13_+_102104952 1.33 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr20_+_33292068 1.23 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
 TP53INP2
 tumor protein p53 inducible nuclear protein 2
chr3_-_178790057 1.12 ENST00000311417.2
 ZMAT3
 zinc finger, matrin-type 3
chr5_+_95066823 1.10 ENST00000506817.1
ENST00000379982.3
 RHOBTB3
 Rho-related BTB domain containing 3
chr3_-_178789220 1.07 ENST00000414084.1
 ZMAT3
 zinc finger, matrin-type 3
chr6_-_31697563 1.03 ENST00000375789.2
ENST00000416410.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr8_-_95961578 0.85 ENST00000448464.2
ENST00000342697.4
 TP53INP1
 tumor protein p53 inducible nuclear protein 1
chr19_+_18208603 0.79 ENST00000262811.6
 MAST3
 microtubule associated serine/threonine kinase 3
chr11_-_111783595 0.71 ENST00000528628.1
 CRYAB
 crystallin, alpha B
chr8_-_13134045 0.71 ENST00000512044.2
 DLC1
 deleted in liver cancer 1
chr1_+_223101757 0.70 ENST00000284476.6
 DISP1
 dispatched homolog 1 (Drosophila)
chr1_+_78354297 0.64 ENST00000334785.7
 NEXN
 nexilin (F actin binding protein)
chr6_-_24911195 0.64 ENST00000259698.4
 FAM65B
 family with sequence similarity 65, member B
chr11_-_70507901 0.62 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
 SHANK2
 SH3 and multiple ankyrin repeat domains 2
chr22_+_31003133 0.61 ENST00000405742.3
 TCN2
 transcobalamin II
chr17_-_7145106 0.60 ENST00000577035.1
 GABARAP
 GABA(A) receptor-associated protein
chr2_-_190044480 0.60 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr13_-_33859819 0.59 ENST00000336934.5
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr6_-_117747015 0.59 ENST00000368508.3
ENST00000368507.3
 ROS1
 c-ros oncogene 1 , receptor tyrosine kinase
chr15_-_52944231 0.59 ENST00000546305.2
 FAM214A
 family with sequence similarity 214, member A
chr4_-_89619386 0.58 ENST00000323061.5
 NAP1L5
 nucleosome assembly protein 1-like 5
chr22_+_35776828 0.58 ENST00000216117.8
 HMOX1
 heme oxygenase (decycling) 1
chr12_-_54121212 0.58 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
 CALCOCO1
 calcium binding and coiled-coil domain 1
chr1_+_78354175 0.57 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
 NEXN
 nexilin (F actin binding protein)
chr22_+_31002779 0.57 ENST00000215838.3
 TCN2
 transcobalamin II
chr12_-_54121261 0.55 ENST00000549784.1
ENST00000262059.4
 CALCOCO1
 calcium binding and coiled-coil domain 1
chr16_-_31076332 0.54 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
 ZNF668
 zinc finger protein 668
chr13_-_43566301 0.54 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
 EPSTI1
 epithelial stromal interaction 1 (breast)
chr5_-_95158644 0.54 ENST00000237858.6
 GLRX
 glutaredoxin (thioltransferase)
chr12_-_56236734 0.53 ENST00000548629.1
 MMP19
 matrix metallopeptidase 19
chr6_+_155470243 0.53 ENST00000456877.2
ENST00000528391.2
 TIAM2
 T-cell lymphoma invasion and metastasis 2
chr6_+_155537771 0.52 ENST00000275246.7
 TIAM2
 T-cell lymphoma invasion and metastasis 2
chr1_-_42384343 0.52 ENST00000372584.1
 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
chr10_-_102089729 0.51 ENST00000465680.2
 PKD2L1
 polycystic kidney disease 2-like 1
chr1_-_86043921 0.48 ENST00000535924.2
 DDAH1
 dimethylarginine dimethylaminohydrolase 1
chr9_-_123239632 0.48 ENST00000416449.1
 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
chr20_+_62697564 0.47 ENST00000458442.1
 TCEA2
 transcription elongation factor A (SII), 2
chrX_-_107019181 0.46 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
 TSC22D3
 TSC22 domain family, member 3
chr2_-_175629135 0.45 ENST00000409542.1
ENST00000409219.1
 CHRNA1
 cholinergic receptor, nicotinic, alpha 1 (muscle)
chr9_+_17134980 0.44 ENST00000380647.3
 CNTLN
 centlein, centrosomal protein
chr1_-_243326612 0.43 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
 CEP170
 centrosomal protein 170kDa
chr12_-_108733078 0.43 ENST00000552995.1
ENST00000312143.7
ENST00000397688.2
ENST00000550402.1
 CMKLR1
 chemokine-like receptor 1
chr2_-_128400788 0.42 ENST00000409286.1
 LIMS2
 LIM and senescent cell antigen-like domains 2
chr16_-_31105870 0.41 ENST00000394971.3
 VKORC1
 vitamin K epoxide reductase complex, subunit 1
chr2_+_30370382 0.41 ENST00000402708.1
 YPEL5
 yippee-like 5 (Drosophila)
chr9_+_131174024 0.39 ENST00000420034.1
ENST00000372842.1
 CERCAM
 cerebral endothelial cell adhesion molecule
chr16_-_31106048 0.39 ENST00000300851.6
 VKORC1
 vitamin K epoxide reductase complex, subunit 1
chr2_+_54198210 0.39 ENST00000607452.1
ENST00000422521.2
 ACYP2
 acylphosphatase 2, muscle type
chr14_+_24584508 0.39 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
 DCAF11
 DDB1 and CUL4 associated factor 11
chr1_+_159750776 0.39 ENST00000368107.1
 DUSP23
 dual specificity phosphatase 23
chr10_+_1102721 0.38 ENST00000263150.4
 WDR37
 WD repeat domain 37
chr16_-_31106211 0.38 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
 RP11-196G11.1
VKORC1
 Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr22_+_31003190 0.38 ENST00000407817.3
 TCN2
 transcobalamin II
chrX_-_150067173 0.38 ENST00000370377.3
ENST00000320893.6
 CD99L2
 CD99 molecule-like 2
chr1_+_159750720 0.38 ENST00000368109.1
ENST00000368108.3
 DUSP23
 dual specificity phosphatase 23
chr1_-_161993422 0.37 ENST00000367940.2
 OLFML2B
 olfactomedin-like 2B
chr19_+_35521572 0.36 ENST00000262631.5
 SCN1B
 sodium channel, voltage-gated, type I, beta subunit
chr8_+_77593448 0.36 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr8_-_72274095 0.36 ENST00000303824.7
 EYA1
 eyes absent homolog 1 (Drosophila)
chr2_+_56411131 0.36 ENST00000407595.2
 CCDC85A
 coiled-coil domain containing 85A
chr11_-_2160180 0.36 ENST00000381406.4
 IGF2
 insulin-like growth factor 2 (somatomedin A)
chr9_-_104357277 0.35 ENST00000374806.1
 PPP3R2
 protein phosphatase 3, regulatory subunit B, beta
chr16_-_31076273 0.35 ENST00000426488.2
 ZNF668
 zinc finger protein 668
chr11_+_33061543 0.34 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
 TCP11L1
 t-complex 11, testis-specific-like 1
chr2_+_148778570 0.34 ENST00000407073.1
 MBD5
 methyl-CpG binding domain protein 5
chr10_-_64576105 0.34 ENST00000242480.3
ENST00000411732.1
 EGR2
 early growth response 2
chr2_-_158345462 0.34 ENST00000439355.1
ENST00000540637.1
 CYTIP
 cytohesin 1 interacting protein
chr11_+_71938925 0.34 ENST00000538751.1
 INPPL1
 inositol polyphosphate phosphatase-like 1
chr15_+_93447675 0.34 ENST00000536619.1
 CHD2
 chromodomain helicase DNA binding protein 2
chr8_+_77593474 0.33 ENST00000455469.2
ENST00000050961.6
 ZFHX4
 zinc finger homeobox 4
chr5_+_49962772 0.33 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr19_-_46285646 0.32 ENST00000458663.2
 DMPK
 dystrophia myotonica-protein kinase
chr11_+_45918092 0.32 ENST00000395629.2
 MAPK8IP1
 mitogen-activated protein kinase 8 interacting protein 1
chr2_+_95537170 0.32 ENST00000295201.4
 TEKT4
 tektin 4
chr13_+_76362974 0.32 ENST00000497947.2
 LMO7
 LIM domain 7
chr14_-_73493784 0.31 ENST00000553891.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chr3_-_81792780 0.31 ENST00000489715.1
 GBE1
 glucan (1,4-alpha-), branching enzyme 1
chr1_+_10271674 0.31 ENST00000377086.1
 KIF1B
 kinesin family member 1B
chr19_-_46285736 0.31 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
 DMPK
 dystrophia myotonica-protein kinase
chr8_-_72274467 0.31 ENST00000340726.3
 EYA1
 eyes absent homolog 1 (Drosophila)
chr19_+_10527449 0.30 ENST00000592685.1
ENST00000380702.2
 PDE4A
 phosphodiesterase 4A, cAMP-specific
chr17_+_58755184 0.30 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
 BCAS3
 breast carcinoma amplified sequence 3
chr1_-_150849208 0.30 ENST00000358595.5
 ARNT
 aryl hydrocarbon receptor nuclear translocator
chr10_+_95848824 0.29 ENST00000371385.3
ENST00000371375.1
 PLCE1
 phospholipase C, epsilon 1
chr17_-_21156578 0.28 ENST00000399011.2
ENST00000468196.1
 C17orf103
 chromosome 17 open reading frame 103
chr14_-_73493825 0.28 ENST00000318876.5
ENST00000556143.1
 ZFYVE1
 zinc finger, FYVE domain containing 1
chr22_+_35695793 0.28 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
 TOM1
 target of myb1 (chicken)
chrX_-_150067069 0.28 ENST00000466436.1
 CD99L2
 CD99 molecule-like 2
chr4_+_37892682 0.28 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr10_+_13142075 0.27 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
 OPTN
 optineurin
chr2_-_152590946 0.27 ENST00000172853.10
 NEB
 nebulin
chr3_+_191046810 0.27 ENST00000392455.3
ENST00000392456.3
 CCDC50
 coiled-coil domain containing 50
chr12_+_32655048 0.27 ENST00000427716.2
ENST00000266482.3
 FGD4
 FYVE, RhoGEF and PH domain containing 4
chr5_+_102201430 0.27 ENST00000438793.3
ENST00000346918.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr1_-_150849174 0.27 ENST00000515192.1
 ARNT
 aryl hydrocarbon receptor nuclear translocator
chr10_+_13142225 0.26 ENST00000378747.3
 OPTN
 optineurin
chr11_-_67120974 0.26 ENST00000539074.1
ENST00000312419.3
 POLD4
 polymerase (DNA-directed), delta 4, accessory subunit
chr8_-_93029865 0.26 ENST00000422361.2
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_102201687 0.26 ENST00000304400.7
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr11_+_6411670 0.26 ENST00000530395.1
ENST00000527275.1
 SMPD1
 sphingomyelin phosphodiesterase 1, acid lysosomal
chr14_+_23067146 0.26 ENST00000428304.2
 ABHD4
 abhydrolase domain containing 4
chr17_-_66453562 0.26 ENST00000262139.5
ENST00000546360.1
 WIPI1
 WD repeat domain, phosphoinositide interacting 1
chr9_+_2159850 0.26 ENST00000416751.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_-_56122426 0.25 ENST00000551173.1
 CD63
 CD63 molecule
chrX_-_101397433 0.25 ENST00000372774.3
 TCEAL6
 transcription elongation factor A (SII)-like 6
chr1_-_182360498 0.25 ENST00000417584.2
 GLUL
 glutamate-ammonia ligase
chr3_-_64211112 0.25 ENST00000295902.6
 PRICKLE2
 prickle homolog 2 (Drosophila)
chr11_+_6411636 0.25 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
 SMPD1
 sphingomyelin phosphodiesterase 1, acid lysosomal
chr5_+_149569520 0.25 ENST00000230671.2
ENST00000524041.1
 SLC6A7
 solute carrier family 6 (neurotransmitter transporter), member 7
chr2_-_73460334 0.25 ENST00000258083.2
 PRADC1
 protease-associated domain containing 1
chr12_-_76879852 0.25 ENST00000548341.1
 OSBPL8
 oxysterol binding protein-like 8
chr14_-_53019211 0.25 ENST00000557374.1
ENST00000281741.4
 TXNDC16
 thioredoxin domain containing 16
chr1_-_150669500 0.25 ENST00000271732.3
 GOLPH3L
 golgi phosphoprotein 3-like
chr8_-_135522425 0.25 ENST00000521673.1
 ZFAT
 zinc finger and AT hook domain containing
chr17_+_6347761 0.25 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
 FAM64A
 family with sequence similarity 64, member A
chr1_-_150849047 0.24 ENST00000354396.2
ENST00000505755.1
 ARNT
 aryl hydrocarbon receptor nuclear translocator
chr19_+_18699599 0.24 ENST00000450195.2
 C19orf60
 chromosome 19 open reading frame 60
chr20_+_43160409 0.24 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
 PKIG
 protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr4_-_52904425 0.24 ENST00000535450.1
 SGCB
 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr20_-_18477862 0.23 ENST00000337227.4
 RBBP9
 retinoblastoma binding protein 9
chr17_+_6347729 0.23 ENST00000572447.1
 FAM64A
 family with sequence similarity 64, member A
chr10_+_94594351 0.23 ENST00000371552.4
 EXOC6
 exocyst complex component 6
chr19_+_18699535 0.23 ENST00000358607.6
 C19orf60
 chromosome 19 open reading frame 60
chr12_+_12938541 0.23 ENST00000356591.4
 APOLD1
 apolipoprotein L domain containing 1
chr10_-_92681033 0.23 ENST00000371697.3
 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
chr8_-_71519889 0.23 ENST00000521425.1
 TRAM1
 translocation associated membrane protein 1
chr7_-_30029574 0.23 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
 SCRN1
 secernin 1
chr4_+_86699834 0.23 ENST00000395183.2
 ARHGAP24
 Rho GTPase activating protein 24
chr17_+_39394250 0.23 ENST00000254072.6
 KRTAP9-8
 keratin associated protein 9-8
chr14_+_53019993 0.23 ENST00000542169.2
ENST00000555622.1
 GPR137C
 G protein-coupled receptor 137C
chr22_+_30792846 0.23 ENST00000312932.9
ENST00000428195.1
 SEC14L2
 SEC14-like 2 (S. cerevisiae)
chr5_+_102201509 0.22 ENST00000348126.2
ENST00000379787.4
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr17_+_45286387 0.22 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
chr17_-_42345487 0.22 ENST00000262418.6
 SLC4A1
 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr1_-_33647267 0.22 ENST00000291416.5
 TRIM62
 tripartite motif containing 62
chr9_-_21305312 0.22 ENST00000259555.4
 IFNA5
 interferon, alpha 5
chr12_+_109826524 0.22 ENST00000431443.2
 MYO1H
 myosin IH
chr22_+_38071615 0.22 ENST00000215909.5
 LGALS1
 lectin, galactoside-binding, soluble, 1
chr7_-_30029367 0.22 ENST00000242059.5
 SCRN1
 secernin 1
chr2_+_85981008 0.21 ENST00000306279.3
 ATOH8
 atonal homolog 8 (Drosophila)
chr15_-_63448973 0.21 ENST00000462430.1
 RPS27L
 ribosomal protein S27-like
chr14_+_90863327 0.21 ENST00000356978.4
 CALM1
 calmodulin 1 (phosphorylase kinase, delta)
chr7_+_18535854 0.21 ENST00000401921.1
 HDAC9
 histone deacetylase 9
chr1_+_174844645 0.21 ENST00000486220.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr5_+_102201722 0.21 ENST00000274392.9
ENST00000455264.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr21_+_17791838 0.21 ENST00000453910.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr11_+_20044096 0.20 ENST00000533917.1
 NAV2
 neuron navigator 2
chr17_-_79895097 0.20 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
 PYCR1
 pyrroline-5-carboxylate reductase 1
chr2_-_65593784 0.20 ENST00000443619.2
 SPRED2
 sprouty-related, EVH1 domain containing 2
chr17_-_1395954 0.20 ENST00000359786.5
 MYO1C
 myosin IC
chr3_-_46904946 0.20 ENST00000292327.4
 MYL3
 myosin, light chain 3, alkali; ventricular, skeletal, slow
chr21_+_17791648 0.20 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr6_-_110736742 0.20 ENST00000368924.3
ENST00000368923.3
 DDO
 D-aspartate oxidase
chr3_-_46904918 0.20 ENST00000395869.1
 MYL3
 myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_+_42248063 0.20 ENST00000293414.1
 ASB16
 ankyrin repeat and SOCS box containing 16
chr12_+_104458235 0.20 ENST00000229330.4
 HCFC2
 host cell factor C2
chr15_+_83776137 0.20 ENST00000322019.9
 TM6SF1
 transmembrane 6 superfamily member 1
chr18_+_3448455 0.20 ENST00000549780.1
 TGIF1
 TGFB-induced factor homeobox 1
chr19_-_48018203 0.20 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
 NAPA
 N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_-_182641367 0.20 ENST00000508450.1
 RGS8
 regulator of G-protein signaling 8
chr9_-_130952989 0.20 ENST00000415526.1
ENST00000277465.4
 CIZ1
 CDKN1A interacting zinc finger protein 1
chr8_-_74791051 0.19 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
 UBE2W
 ubiquitin-conjugating enzyme E2W (putative)
chrX_+_135278908 0.19 ENST00000539015.1
ENST00000370683.1
 FHL1
 four and a half LIM domains 1
chr12_-_123752624 0.19 ENST00000542174.1
ENST00000535796.1
 CDK2AP1
 cyclin-dependent kinase 2 associated protein 1
chr8_+_81398444 0.19 ENST00000455036.3
ENST00000426744.2
 ZBTB10
 zinc finger and BTB domain containing 10
chr14_+_53019822 0.19 ENST00000321662.6
 GPR137C
 G protein-coupled receptor 137C
chrX_+_135279179 0.19 ENST00000370676.3
 FHL1
 four and a half LIM domains 1
chr15_+_43809797 0.19 ENST00000399453.1
ENST00000300231.5
 MAP1A
 microtubule-associated protein 1A
chr16_-_21289627 0.19 ENST00000396023.2
ENST00000415987.2
 CRYM
 crystallin, mu
chr19_+_36249044 0.19 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
 C19orf55
 chromosome 19 open reading frame 55
chr2_+_62132800 0.19 ENST00000538736.1
 COMMD1
 copper metabolism (Murr1) domain containing 1
chr11_-_67169253 0.19 ENST00000527663.1
ENST00000312989.7
 PPP1CA
 protein phosphatase 1, catalytic subunit, alpha isozyme
chr3_+_54157480 0.19 ENST00000490478.1
 CACNA2D3
 calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr1_-_19638566 0.18 ENST00000330072.5
ENST00000235835.3
 AKR7A2
 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
chr11_-_62323702 0.18 ENST00000530285.1
 AHNAK
 AHNAK nucleoprotein
chr2_+_101437487 0.18 ENST00000427413.1
ENST00000542504.1
 NPAS2
 neuronal PAS domain protein 2
chr8_+_38758737 0.18 ENST00000521746.1
ENST00000420274.1
 PLEKHA2
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr17_+_33570055 0.18 ENST00000299977.4
ENST00000542451.1
ENST00000592325.1
 SLFN5
 schlafen family member 5
chr22_+_31090793 0.18 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
 OSBP2
 oxysterol binding protein 2
chr6_+_69942298 0.18 ENST00000238918.8
 BAI3
 brain-specific angiogenesis inhibitor 3
chr15_+_75628394 0.18 ENST00000564815.1
ENST00000338995.6
 COMMD4
 COMM domain containing 4
chr14_-_69619823 0.18 ENST00000341516.5
 DCAF5
 DDB1 and CUL4 associated factor 5
chr5_-_139930713 0.18 ENST00000602657.1
 SRA1
 steroid receptor RNA activator 1
chr15_+_75628232 0.18 ENST00000267935.8
ENST00000567195.1
 COMMD4
 COMM domain containing 4
chr17_+_39240459 0.18 ENST00000391417.4
 KRTAP4-7
 keratin associated protein 4-7
chr17_-_79895154 0.18 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
 PYCR1
 pyrroline-5-carboxylate reductase 1
chr1_-_31230650 0.18 ENST00000294507.3
 LAPTM5
 lysosomal protein transmembrane 5
chr3_-_99833333 0.17 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
 FILIP1L
 filamin A interacting protein 1-like
chr9_+_99212403 0.17 ENST00000375251.3
ENST00000375249.4
 HABP4
 hyaluronan binding protein 4
chr17_-_79894651 0.17 ENST00000584848.1
ENST00000577756.1
ENST00000329875.8
 PYCR1
 pyrroline-5-carboxylate reductase 1
chr10_+_22605374 0.17 ENST00000448361.1
 COMMD3
 COMM domain containing 3
chr2_+_62132781 0.17 ENST00000311832.5
 COMMD1
 copper metabolism (Murr1) domain containing 1
chr20_-_44485835 0.17 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
 ACOT8
 acyl-CoA thioesterase 8
chr1_+_180165672 0.17 ENST00000443059.1
 QSOX1
 quiescin Q6 sulfhydryl oxidase 1
chr4_-_140223670 0.16 ENST00000394228.1
ENST00000539387.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr16_+_71929397 0.16 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
 IST1
 increased sodium tolerance 1 homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 1.0 GO:0018032 protein amidation(GO:0018032)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.6 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.2 3.0 GO:0006527 arginine catabolic process(GO:0006527)
0.2 1.6 GO:0015889 cobalamin transport(GO:0015889)
0.2 1.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 1.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.2 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1 0.6 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.9 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.3 GO:1904647 response to rotenone(GO:1904647)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.5 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.5 GO:0001554 luteolysis(GO:0001554)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.7 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.4 GO:0006887 exocytosis(GO:0006887)
0.0 0.1 GO:0070213 negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.7 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.2 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 2.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.2 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.1 GO:0043353 slow-twitch skeletal muscle fiber contraction(GO:0031444) enucleate erythrocyte differentiation(GO:0043353)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.0 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.0 GO:1903336 intralumenal vesicle formation(GO:0070676) negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0042599 lamellar body(GO:0042599)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.9 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 2.9 GO:0043204 perikaryon(GO:0043204)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 1.1 GO:0005901 caveola(GO:0005901)
0.0 0.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 1.0 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 0.8 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 1.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.2 GO:0030395 lactose binding(GO:0030395)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.7 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 2.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0000217 DNA secondary structure binding(GO:0000217)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation