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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TGIF1

Z-value: 1.20

Motif logo

Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.16 TGIF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg19_v2_chr18_+_3449330_34494110.531.7e-01Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_33359646 2.58 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_33359687 2.54 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr3_+_45067659 2.42 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr15_-_48937982 2.27 ENST00000316623.5
FBN1
fibrillin 1
chr1_+_163038565 1.85 ENST00000421743.2
RGS4
regulator of G-protein signaling 4
chr4_+_14113592 1.77 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr11_+_6411636 1.35 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr11_+_6411670 1.29 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr13_-_38172863 1.23 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr1_+_79086088 1.19 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr1_+_221051699 1.17 ENST00000366903.6
HLX
H2.0-like homeobox
chr17_-_53809473 1.10 ENST00000575734.1
TMEM100
transmembrane protein 100
chr2_+_24714729 1.06 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr5_-_19988339 1.01 ENST00000382275.1
CDH18
cadherin 18, type 2
chr4_-_175443943 1.00 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr4_+_55095264 0.95 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr7_+_95401851 0.93 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr3_+_69788576 0.92 ENST00000352241.4
ENST00000448226.2
MITF
microphthalmia-associated transcription factor
chr1_+_6615241 0.91 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr10_-_79398127 0.90 ENST00000372443.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_+_2880157 0.89 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr11_+_71938925 0.84 ENST00000538751.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr9_-_79307096 0.83 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr16_+_2880369 0.81 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr10_-_79398250 0.81 ENST00000286627.5
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_+_63897605 0.78 ENST00000487717.1
ATXN7
ataxin 7
chr5_+_32788945 0.75 ENST00000326958.1
AC026703.1
AC026703.1
chr12_+_108908962 0.72 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
FICD
FIC domain containing
chr1_-_149889382 0.71 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr17_-_66951474 0.71 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr2_-_145275228 0.69 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr12_+_65672423 0.68 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
MSRB3
methionine sulfoxide reductase B3
chr16_+_2880254 0.68 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr2_+_128177458 0.67 ENST00000409048.1
ENST00000422777.3
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr20_+_34802295 0.66 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr4_-_175443484 0.66 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr16_+_2880296 0.65 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr5_+_141348721 0.65 ENST00000507163.1
ENST00000394519.1
RNF14
ring finger protein 14
chr18_-_54305658 0.64 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr5_-_159797627 0.63 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr3_-_52719810 0.61 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr10_-_49860525 0.61 ENST00000435790.2
ARHGAP22
Rho GTPase activating protein 22
chr6_+_73076432 0.59 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_141348640 0.56 ENST00000540015.1
ENST00000506938.1
ENST00000394514.2
ENST00000512565.1
ENST00000394515.3
RNF14
ring finger protein 14
chr5_+_180257951 0.56 ENST00000501855.2
LINC00847
long intergenic non-protein coding RNA 847
chrX_-_99986494 0.55 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
SYTL4
synaptotagmin-like 4
chr3_-_127541679 0.55 ENST00000265052.5
MGLL
monoglyceride lipase
chr5_+_180257974 0.54 ENST00000502162.2
ENST00000508309.1
ENST00000509921.1
LINC00847
long intergenic non-protein coding RNA 847
chr1_-_241799232 0.54 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chrX_-_153775426 0.54 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr11_+_67776012 0.54 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr11_+_12132117 0.54 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr12_+_59989918 0.53 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr11_+_46316677 0.53 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr11_+_20044600 0.53 ENST00000311043.8
NAV2
neuron navigator 2
chr4_-_175443788 0.53 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr20_-_3996165 0.53 ENST00000545616.2
ENST00000358395.6
RNF24
ring finger protein 24
chr12_+_65672702 0.52 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr2_+_228678550 0.51 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr13_+_50570019 0.51 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr12_-_63328817 0.50 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr10_+_1102721 0.50 ENST00000263150.4
WDR37
WD repeat domain 37
chr4_+_77870960 0.50 ENST00000505788.1
ENST00000510515.1
ENST00000504637.1
SEPT11
septin 11
chr6_-_31651817 0.50 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr12_+_59989791 0.49 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_-_33168336 0.48 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr9_-_16728161 0.47 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr15_-_82338460 0.47 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr4_+_166300084 0.46 ENST00000402744.4
CPE
carboxypeptidase E
chr10_-_49812997 0.46 ENST00000417912.2
ARHGAP22
Rho GTPase activating protein 22
chr10_-_14372870 0.46 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr7_+_95401877 0.45 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr16_+_27413483 0.45 ENST00000337929.3
ENST00000564089.1
IL21R
interleukin 21 receptor
chr3_-_127542051 0.44 ENST00000398104.1
MGLL
monoglyceride lipase
chr3_-_127542021 0.44 ENST00000434178.2
MGLL
monoglyceride lipase
chrX_-_48931648 0.44 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr3_-_18466026 0.43 ENST00000417717.2
SATB1
SATB homeobox 1
chr3_+_106959530 0.42 ENST00000466734.1
ENST00000463143.1
ENST00000490441.1
LINC00883
long intergenic non-protein coding RNA 883
chr2_-_73460334 0.42 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr7_+_134551583 0.42 ENST00000435928.1
CALD1
caldesmon 1
chr8_-_93029520 0.42 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_111781454 0.41 ENST00000533280.1
CRYAB
crystallin, alpha B
chr9_+_34652164 0.41 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr17_-_76899275 0.41 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chr15_+_75498739 0.41 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr7_-_152133059 0.41 ENST00000262189.6
ENST00000355193.2
KMT2C
lysine (K)-specific methyltransferase 2C
chr20_-_3996036 0.41 ENST00000336095.6
RNF24
ring finger protein 24
chr17_+_68165657 0.40 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr8_-_93029865 0.40 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_186990298 0.40 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr16_+_2588012 0.40 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr11_-_111781554 0.39 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr5_+_76011868 0.39 ENST00000319211.4
F2R
coagulation factor II (thrombin) receptor
chr16_-_2260834 0.39 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr5_+_157170703 0.39 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr5_-_78281603 0.38 ENST00000264914.4
ARSB
arylsulfatase B
chr5_+_140868717 0.38 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr9_+_17134980 0.38 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr18_+_66465302 0.38 ENST00000360242.5
ENST00000358653.5
CCDC102B
coiled-coil domain containing 102B
chr12_+_100041527 0.38 ENST00000324341.1
FAM71C
family with sequence similarity 71, member C
chr10_+_124768482 0.37 ENST00000368869.4
ENST00000358776.4
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr1_+_22379179 0.37 ENST00000315554.8
ENST00000421089.2
CDC42
cell division cycle 42
chr11_-_111781610 0.37 ENST00000525823.1
CRYAB
crystallin, alpha B
chr5_+_76012009 0.37 ENST00000505600.1
F2R
coagulation factor II (thrombin) receptor
chr2_+_239756671 0.37 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr22_-_36013368 0.36 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr9_+_125273081 0.36 ENST00000335302.5
OR1J2
olfactory receptor, family 1, subfamily J, member 2
chr12_+_55248289 0.36 ENST00000308796.6
MUCL1
mucin-like 1
chr7_-_100493482 0.35 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr19_-_40791211 0.34 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr5_+_72143988 0.34 ENST00000506351.2
TNPO1
transportin 1
chr16_+_50775971 0.34 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr8_-_42065075 0.34 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr5_+_139505520 0.34 ENST00000333305.3
IGIP
IgA-inducing protein
chr17_-_7145475 0.33 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr3_-_39234074 0.33 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1
chr3_-_183735651 0.33 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_-_141646726 0.33 ENST00000438351.1
ENST00000439991.1
ENST00000551012.2
ENST00000546910.1
CLEC5A
C-type lectin domain family 5, member A
chr3_-_127541194 0.33 ENST00000453507.2
MGLL
monoglyceride lipase
chr5_-_127873896 0.33 ENST00000502468.1
FBN2
fibrillin 2
chr5_-_139930713 0.33 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr4_+_128886424 0.32 ENST00000398965.1
C4orf29
chromosome 4 open reading frame 29
chr6_+_108881012 0.32 ENST00000343882.6
FOXO3
forkhead box O3
chr5_+_141348598 0.32 ENST00000394520.2
ENST00000347642.3
RNF14
ring finger protein 14
chr16_-_67217844 0.31 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr2_+_46926048 0.31 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr19_-_38714847 0.31 ENST00000420980.2
ENST00000355526.4
DPF1
D4, zinc and double PHD fingers family 1
chr20_-_5591626 0.31 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr15_-_43559055 0.31 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr17_+_64298944 0.31 ENST00000413366.3
PRKCA
protein kinase C, alpha
chr9_-_99540328 0.31 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr4_-_2420357 0.31 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28
zinc finger, FYVE domain containing 28
chr13_+_96329381 0.31 ENST00000602402.1
ENST00000376795.6
DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr11_+_111848024 0.31 ENST00000315253.5
DIXDC1
DIX domain containing 1
chr2_+_96331830 0.30 ENST00000425887.2
AC008268.1
AC008268.1
chr8_-_29120580 0.30 ENST00000524189.1
KIF13B
kinesin family member 13B
chrX_-_71525742 0.30 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr9_-_16727978 0.29 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr15_-_37392086 0.29 ENST00000561208.1
MEIS2
Meis homeobox 2
chr21_+_25801041 0.29 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr16_+_2198604 0.29 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr11_+_120973375 0.29 ENST00000264037.2
TECTA
tectorin alpha
chr8_+_22446763 0.29 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
AC037459.4
Uncharacterized protein
chr2_+_37311588 0.29 ENST00000409774.1
ENST00000608836.1
GPATCH11
G patch domain containing 11
chr9_-_115653176 0.29 ENST00000374228.4
SLC46A2
solute carrier family 46, member 2
chr14_+_103566481 0.29 ENST00000380069.3
EXOC3L4
exocyst complex component 3-like 4
chr1_+_240177627 0.29 ENST00000447095.1
FMN2
formin 2
chr3_-_190580404 0.29 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr8_+_71485681 0.28 ENST00000391684.1
AC120194.1
AC120194.1
chr16_+_53088885 0.28 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr8_+_28174649 0.28 ENST00000301908.3
PNOC
prepronociceptin
chr12_+_15475462 0.28 ENST00000543886.1
ENST00000348962.2
PTPRO
protein tyrosine phosphatase, receptor type, O
chr19_-_10121144 0.28 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr3_-_3221358 0.28 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr17_-_7145106 0.28 ENST00000577035.1
GABARAP
GABA(A) receptor-associated protein
chr3_+_169629354 0.28 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr6_-_111804905 0.28 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr10_+_94608245 0.28 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr5_-_133968529 0.27 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr21_+_44394620 0.27 ENST00000291547.5
PKNOX1
PBX/knotted 1 homeobox 1
chr5_+_133984462 0.27 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr12_+_15475331 0.27 ENST00000281171.4
PTPRO
protein tyrosine phosphatase, receptor type, O
chr10_-_48438974 0.27 ENST00000224605.2
GDF10
growth differentiation factor 10
chr10_-_90751038 0.27 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_+_38085731 0.27 ENST00000589117.1
ZNF540
zinc finger protein 540
chr11_-_111794446 0.27 ENST00000527950.1
CRYAB
crystallin, alpha B
chr6_+_33378738 0.27 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr5_+_149887672 0.26 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_+_50775948 0.26 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_3227877 0.26 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr17_+_36858694 0.26 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr17_-_72358001 0.26 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr9_-_132805430 0.25 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chrX_-_134429952 0.25 ENST00000370764.1
ZNF75D
zinc finger protein 75D
chr3_+_112280857 0.25 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr20_-_62601218 0.25 ENST00000369888.1
ZNF512B
zinc finger protein 512B
chr5_+_134240588 0.24 ENST00000254908.6
PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr12_+_103981044 0.24 ENST00000388887.2
STAB2
stabilin 2
chr5_-_132113083 0.24 ENST00000296873.7
SEPT8
septin 8
chr17_+_26646175 0.24 ENST00000583381.1
ENST00000582113.1
ENST00000582384.1
TMEM97
transmembrane protein 97
chr16_+_31366536 0.24 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr18_+_3449330 0.24 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr2_+_37311645 0.24 ENST00000281932.5
GPATCH11
G patch domain containing 11
chr4_-_114682364 0.24 ENST00000511664.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr1_-_53163992 0.24 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr1_+_150039369 0.24 ENST00000369130.3
ENST00000369128.5
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr5_-_132112921 0.24 ENST00000378721.4
ENST00000378701.1
SEPT8
septin 8
chrX_+_101967257 0.24 ENST00000543253.1
ENST00000535209.1
GPRASP2
G protein-coupled receptor associated sorting protein 2
chr16_-_30582888 0.23 ENST00000563707.1
ENST00000567855.1
ZNF688
zinc finger protein 688
chr14_+_31494672 0.23 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr11_-_78128811 0.23 ENST00000530915.1
ENST00000361507.4
GAB2
GRB2-associated binding protein 2
chr14_+_31494841 0.23 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr15_+_75335604 0.23 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr6_+_83777374 0.22 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1
dopey family member 1
chr11_-_26743546 0.22 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr19_+_38085768 0.22 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
ZNF540
zinc finger protein 540
chr4_-_114682936 0.22 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr6_+_147527103 0.22 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr11_-_6426635 0.22 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr10_+_94352956 0.22 ENST00000260731.3
KIF11
kinesin family member 11

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.4 2.6 GO:0023021 termination of signal transduction(GO:0023021)
0.4 1.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.3 2.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 1.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 1.0 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 1.2 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.2 2.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 0.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 1.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 0.7 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 0.8 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 0.5 GO:0019417 sulfur oxidation(GO:0019417)
0.2 0.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.3 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 1.7 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.4 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 1.0 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 1.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.5 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 1.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.2 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:0061110 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.4 GO:0034343 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.3 GO:0009644 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.1 1.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.1 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 0.2 GO:0071338 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.5 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.3 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.2 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.2 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.2 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.2 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.7 GO:1901725 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) regulation of histone deacetylase activity(GO:1901725)
0.0 0.6 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0042322 positive regulation of growth rate(GO:0040010) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499) negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.6 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 3.2 GO:0001895 retina homeostasis(GO:0001895)
0.0 1.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.4 GO:0003012 muscle system process(GO:0003012)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.1 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.3 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.8 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.4 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0060440 trachea formation(GO:0060440)
0.0 0.1 GO:0035701 immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0042262 DNA protection(GO:0042262)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0060004 reflex(GO:0060004)
0.0 0.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.3 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.1 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.2 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0001652 granular component(GO:0001652)
0.3 7.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 1.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.8 GO:0042599 lamellar body(GO:0042599)
0.1 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.4 GO:0071204 U7 snRNP(GO:0005683) histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 2.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.0 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.8 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0099503 secretory vesicle(GO:0099503)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0050436 microfibril binding(GO:0050436)
0.5 2.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 2.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 1.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 1.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 1.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 0.6 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 2.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.4 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 1.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 1.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.3 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.9 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.6 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 5.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 6.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 2.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway