Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TLX2 Links Ensembl NCBI GeneCards UniProt	ENSG00000115297.9	TLX2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TLX2	hg19_v2_chr2_+_74741569_74741620	-0.43	2.8e-01	Click!

View svg image
View png image

Promoter	Score	Transcript	Gene	Gene Info
chr1_+_86889769	1.21	ENST00000370565.4	CLCA2	chloride channel accessory 2
chr11_+_69924639	1.17	ENST00000538023.1 ENST00000398543.2	ANO1	anoctamin 1, calcium activated chloride channel
chr15_+_41136586	1.07	ENST00000431806.1	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr1_-_120935894	1.05	ENST00000369383.4 ENST00000369384.4	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr8_+_86376081	1.00	ENST00000285379.5	CA2	carbonic anhydrase II
chr10_+_47746929	0.88	ENST00000340243.6 ENST00000374277.5 ENST00000449464.2 ENST00000538825.1 ENST00000335083.5	ANXA8L2 AL603965.1	annexin A8-like 2 Protein LOC100996760
chr19_-_6767516	0.83	ENST00000245908.6	SH2D3A	SH2 domain containing 3A
chr1_-_153363452	0.82	ENST00000368732.1 ENST00000368733.3	S100A8	S100 calcium binding protein A8
chr6_-_138428613	0.76	ENST00000421351.3	PERP	PERP, TP53 apoptosis effector
chr10_+_48255253	0.75	ENST00000357718.4 ENST00000344416.5 ENST00000456111.2 ENST00000374258.3	ANXA8 AL591684.1	annexin A8 Protein LOC100996760
chr14_+_65171315	0.71	ENST00000394691.1	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_+_17721920	0.69	ENST00000295156.4	VSNL1	visinin-like 1
chr16_-_68269971	0.69	ENST00000565858.1	ESRP2	epithelial splicing regulatory protein 2
chr1_+_95286151	0.68	ENST00000467909.1 ENST00000422520.2 ENST00000532427.1	SLC44A3	solute carrier family 44, member 3
chr5_+_131409476	0.63	ENST00000296871.2	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr18_+_28956740	0.60	ENST00000308128.4 ENST00000359747.4	DSG4	desmoglein 4
chr12_+_101188547	0.60	ENST00000546991.1 ENST00000392979.3	ANO4	anoctamin 4
chr5_+_68710906	0.58	ENST00000325631.5 ENST00000454295.2	MARVELD2	MARVEL domain containing 2
chr19_-_6767431	0.57	ENST00000437152.3 ENST00000597687.1	SH2D3A	SH2 domain containing 3A
chr16_+_57406368	0.57	ENST00000006053.6 ENST00000563383.1	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr12_-_95611149	0.57	ENST00000549499.1 ENST00000343958.4 ENST00000546711.1	FGD6	FYVE, RhoGEF and PH domain containing 6
chr1_+_153330322	0.57	ENST00000368738.3	S100A9	S100 calcium binding protein A9
chr12_+_101188718	0.57	ENST00000299222.9 ENST00000392977.3	ANO4	anoctamin 4
chr10_-_47173994	0.55	ENST00000414655.2 ENST00000545298.1 ENST00000359178.4 ENST00000358140.4 ENST00000503031.1	ANXA8L1 LINC00842	annexin A8-like 1 long intergenic non-protein coding RNA 842
chr3_+_50192537	0.54	ENST00000002829.3	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192499	0.52	ENST00000413852.1	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr20_-_14318248	0.52	ENST00000378053.3 ENST00000341420.4	FLRT3	fibronectin leucine rich transmembrane protein 3
chr12_+_56732658	0.52	ENST00000228534.4	IL23A	interleukin 23, alpha subunit p19
chr14_+_65171099	0.52	ENST00000247226.7	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_-_6526192	0.51	ENST00000377782.3 ENST00000351959.5 ENST00000356876.3	TNFRSF25	tumor necrosis factor receptor superfamily, member 25
chr1_-_24469602	0.51	ENST00000270800.1	IL22RA1	interleukin 22 receptor, alpha 1
chr1_+_152881014	0.50	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr1_+_62417957	0.50	ENST00000307297.7 ENST00000543708.1	INADL	InaD-like (Drosophila)
chr3_+_124355944	0.50	ENST00000459915.1	KALRN	kalirin, RhoGEF kinase
chr7_-_32111009	0.50	ENST00000396184.3 ENST00000396189.2 ENST00000321453.7	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr19_-_51512804	0.49	ENST00000594211.1 ENST00000376832.4	KLK9	kallikrein-related peptidase 9
chr1_+_152486950	0.47	ENST00000368790.3	CRCT1	cysteine-rich C-terminal 1
chr3_+_121796697	0.47	ENST00000482356.1 ENST00000393627.2	CD86	CD86 molecule
chr7_+_89783689	0.46	ENST00000297205.2	STEAP1	six transmembrane epithelial antigen of the prostate 1
chr11_+_117947782	0.45	ENST00000522307.1 ENST00000523251.1 ENST00000437212.3 ENST00000522824.1 ENST00000522151.1	TMPRSS4	transmembrane protease, serine 4
chr6_-_52109335	0.45	ENST00000336123.4	IL17F	interleukin 17F
chr19_+_50084561	0.44	ENST00000246794.5	PRRG2	proline rich Gla (G-carboxyglutamic acid) 2
chr8_+_120220561	0.44	ENST00000276681.6	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_-_182880541	0.43	ENST00000470251.1 ENST00000265598.3	LAMP3	lysosomal-associated membrane protein 3
chrX_-_45629661	0.42	ENST00000602507.1 ENST00000602461.1	RP6-99M1.2	RP6-99M1.2
chr18_+_29077990	0.42	ENST00000261590.8	DSG2	desmoglein 2
chr3_-_149051194	0.42	ENST00000470080.1	TM4SF18	transmembrane 4 L six family member 18
chr12_-_71031220	0.41	ENST00000334414.6	PTPRB	protein tyrosine phosphatase, receptor type, B
chrX_+_38420623	0.41	ENST00000378482.2	TSPAN7	tetraspanin 7
chr12_-_71031185	0.40	ENST00000548122.1 ENST00000551525.1 ENST00000550358.1	PTPRB	protein tyrosine phosphatase, receptor type, B
chr17_-_46507537	0.40	ENST00000336915.6	SKAP1	src kinase associated phosphoprotein 1
chr16_+_82068830	0.40	ENST00000199936.4	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr1_+_9711781	0.39	ENST00000536656.1 ENST00000377346.4	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr7_-_22539771	0.39	ENST00000406890.2 ENST00000424363.1	STEAP1B	STEAP family member 1B
chr6_+_106546808	0.38	ENST00000369089.3	PRDM1	PR domain containing 1, with ZNF domain
chr14_+_61789382	0.38	ENST00000555082.1	PRKCH	protein kinase C, eta
chr16_+_5121814	0.38	ENST00000262374.5 ENST00000586840.1	ALG1	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr12_+_6494285	0.37	ENST00000541102.1	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr11_+_117947724	0.37	ENST00000534111.1	TMPRSS4	transmembrane protease, serine 4
chr1_-_6526167	0.37	ENST00000351748.3 ENST00000348333.3	TNFRSF25	tumor necrosis factor receptor superfamily, member 25
chr15_-_34502197	0.36	ENST00000557877.1	KATNBL1	katanin p80 subunit B-like 1
chr11_+_35160709	0.36	ENST00000415148.2 ENST00000433354.2 ENST00000449691.2 ENST00000437706.2 ENST00000360158.4 ENST00000428726.2 ENST00000526669.2 ENST00000433892.2 ENST00000278386.6 ENST00000434472.2 ENST00000352818.4 ENST00000442151.2	CD44	CD44 molecule (Indian blood group)
chr9_+_35673853	0.33	ENST00000378357.4	CA9	carbonic anhydrase IX
chr6_+_116692102	0.33	ENST00000359564.2	DSE	dermatan sulfate epimerase
chr1_+_24646002	0.33	ENST00000356046.2	GRHL3	grainyhead-like 3 (Drosophila)
chr19_+_676385	0.33	ENST00000166139.4	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr1_-_217262933	0.33	ENST00000359162.2	ESRRG	estrogen-related receptor gamma
chr1_+_24645865	0.32	ENST00000342072.4	GRHL3	grainyhead-like 3 (Drosophila)
chr1_-_217262969	0.32	ENST00000361525.3	ESRRG	estrogen-related receptor gamma
chr4_-_36246060	0.31	ENST00000303965.4	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_24645807	0.31	ENST00000361548.4	GRHL3	grainyhead-like 3 (Drosophila)
chr8_+_98900132	0.31	ENST00000520016.1	MATN2	matrilin 2
chr17_-_76128488	0.30	ENST00000322914.3	TMC6	transmembrane channel-like 6
chr4_+_41937131	0.30	ENST00000504986.1 ENST00000508448.1 ENST00000513702.1 ENST00000325094.5	TMEM33	transmembrane protein 33
chr8_-_105601134	0.30	ENST00000276654.5 ENST00000424843.2	LRP12	low density lipoprotein receptor-related protein 12
chr8_+_80523962	0.29	ENST00000518491.1	STMN2	stathmin-like 2
chr10_-_103880209	0.29	ENST00000425280.1	LDB1	LIM domain binding 1
chr21_-_16437255	0.29	ENST00000400199.1 ENST00000400202.1	NRIP1	nuclear receptor interacting protein 1
chr3_+_118892362	0.29	ENST00000497685.1 ENST00000264234.3	UPK1B	uroplakin 1B
chr1_+_160160346	0.28	ENST00000368078.3	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr21_-_16437126	0.28	ENST00000318948.4	NRIP1	nuclear receptor interacting protein 1
chr12_+_9144626	0.28	ENST00000543895.1	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr3_+_121774202	0.28	ENST00000469710.1 ENST00000493101.1 ENST00000330540.2 ENST00000264468.5	CD86	CD86 molecule
chr1_-_11042094	0.28	ENST00000377004.4 ENST00000377008.4	C1orf127	chromosome 1 open reading frame 127
chr1_+_160160283	0.27	ENST00000368079.3	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr8_+_80523321	0.27	ENST00000518111.1	STMN2	stathmin-like 2
chr6_+_84563295	0.27	ENST00000369687.1	RIPPLY2	ripply transcriptional repressor 2
chr4_-_165305086	0.27	ENST00000507270.1 ENST00000514618.1 ENST00000503008.1	MARCH1	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_-_239197201	0.26	ENST00000254658.3	PER2	period circadian clock 2
chr1_-_165324983	0.26	ENST00000367893.4	LMX1A	LIM homeobox transcription factor 1, alpha
chr19_+_39421556	0.26	ENST00000407800.2 ENST00000402029.3	MRPS12	mitochondrial ribosomal protein S12
chr13_-_50265570	0.26	ENST00000378270.5 ENST00000378284.2 ENST00000378272.5 ENST00000378268.1 ENST00000242827.6 ENST00000378282.5	EBPL	emopamil binding protein-like
chr12_+_19358228	0.26	ENST00000424268.1 ENST00000543806.1	PLEKHA5	pleckstrin homology domain containing, family A member 5
chr19_-_11688447	0.25	ENST00000590420.1	ACP5	acid phosphatase 5, tartrate resistant
chr12_-_120763739	0.25	ENST00000549767.1	PLA2G1B	phospholipase A2, group IB (pancreas)
chr2_-_62733476	0.25	ENST00000335390.5	TMEM17	transmembrane protein 17
chr2_-_72375167	0.25	ENST00000001146.2	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr20_-_50418947	0.25	ENST00000371539.3	SALL4	spalt-like transcription factor 4
chr2_+_204801471	0.24	ENST00000316386.6 ENST00000435193.1	ICOS	inducible T-cell co-stimulator
chr1_-_36947120	0.24	ENST00000361632.4	CSF3R	colony stimulating factor 3 receptor (granulocyte)
chr10_-_50970322	0.23	ENST00000374103.4	OGDHL	oxoglutarate dehydrogenase-like
chr14_-_67859422	0.23	ENST00000556532.1	PLEK2	pleckstrin 2
chr1_-_25291475	0.23	ENST00000338888.3 ENST00000399916.1	RUNX3	runt-related transcription factor 3
chr17_+_7211280	0.23	ENST00000419711.2 ENST00000571955.1 ENST00000573714.1	EIF5A	eukaryotic translation initiation factor 5A
chr10_-_50970382	0.23	ENST00000419399.1 ENST00000432695.1	OGDHL	oxoglutarate dehydrogenase-like
chr11_-_102323740	0.23	ENST00000398136.2	TMEM123	transmembrane protein 123
chr11_+_67159416	0.23	ENST00000307980.2 ENST00000544620.1	RAD9A	RAD9 homolog A (S. pombe)
chr19_-_36342739	0.22	ENST00000378910.5 ENST00000353632.6	NPHS1	nephrosis 1, congenital, Finnish type (nephrin)
chr16_-_28222797	0.22	ENST00000569951.1 ENST00000565698.1	XPO6	exportin 6
chr1_+_36789335	0.22	ENST00000373137.2	RP11-268J15.5	RP11-268J15.5
chr4_+_17812525	0.22	ENST00000251496.2	NCAPG	non-SMC condensin I complex, subunit G
chr14_+_23340822	0.22	ENST00000359591.4	LRP10	low density lipoprotein receptor-related protein 10
chr11_-_1036706	0.22	ENST00000421673.2	MUC6	mucin 6, oligomeric mucus/gel-forming
chr3_+_184098065	0.22	ENST00000348986.3	CHRD	chordin
chrX_+_56259316	0.21	ENST00000468660.1	KLF8	Kruppel-like factor 8
chr11_+_128563652	0.21	ENST00000527786.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr11_-_57089671	0.21	ENST00000532437.1	TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr19_+_1067271	0.21	ENST00000536472.1 ENST00000590214.1	HMHA1	histocompatibility (minor) HA-1
chr16_+_81478775	0.21	ENST00000537098.3	CMIP	c-Maf inducing protein
chr8_+_133879193	0.21	ENST00000377869.1 ENST00000220616.4	TG	thyroglobulin
chr16_-_88851618	0.21	ENST00000301015.9	PIEZO1	piezo-type mechanosensitive ion channel component 1
chr22_+_31477296	0.21	ENST00000426927.1 ENST00000440425.1 ENST00000358743.1 ENST00000347557.2 ENST00000333137.7	SMTN	smoothelin
chr8_-_145018905	0.21	ENST00000398774.2	PLEC	plectin
chrX_-_31285042	0.21	ENST00000378680.2 ENST00000378723.3	DMD	dystrophin
chr16_-_72206034	0.20	ENST00000537465.1 ENST00000237353.10	PMFBP1	polyamine modulated factor 1 binding protein 1
chr4_-_75719896	0.20	ENST00000395743.3	BTC	betacellulin
chr9_-_117692697	0.20	ENST00000223795.2	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8
chr10_-_50396425	0.20	ENST00000374148.1	C10orf128	chromosome 10 open reading frame 128
chr4_-_68411275	0.20	ENST00000273853.6	CENPC	centromere protein C
chr12_-_54785074	0.20	ENST00000338010.5 ENST00000550774.1	ZNF385A	zinc finger protein 385A
chr10_-_44880491	0.20	ENST00000374426.2 ENST00000395795.4 ENST00000395794.2 ENST00000374429.2 ENST00000395793.3 ENST00000343575.6	CXCL12	chemokine (C-X-C motif) ligand 12
chr9_-_128003606	0.20	ENST00000324460.6	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr15_-_34628951	0.20	ENST00000397707.2 ENST00000560611.1	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6
chr5_-_524445	0.20	ENST00000514375.1 ENST00000264938.3	SLC9A3	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
chr1_+_205473720	0.20	ENST00000429964.2 ENST00000506784.1 ENST00000360066.2	CDK18	cyclin-dependent kinase 18
chr12_-_322504	0.20	ENST00000424061.2	SLC6A12	solute carrier family 6 (neurotransmitter transporter), member 12
chr1_+_231114795	0.20	ENST00000310256.2 ENST00000366658.2 ENST00000450711.1 ENST00000435927.1	ARV1	ARV1 homolog (S. cerevisiae)
chr20_-_47894936	0.19	ENST00000371754.4	ZNFX1	zinc finger, NFX1-type containing 1
chr12_-_89918522	0.19	ENST00000529983.2	GALNT4	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr14_+_92980111	0.19	ENST00000216487.7 ENST00000557762.1	RIN3	Ras and Rab interactor 3
chr13_+_113777105	0.19	ENST00000409306.1 ENST00000375551.3 ENST00000375559.3	F10	coagulation factor X
chr4_-_147443043	0.19	ENST00000394059.4 ENST00000502607.1 ENST00000335472.7 ENST00000432059.2 ENST00000394062.3	SLC10A7	solute carrier family 10, member 7
chr1_-_31902614	0.19	ENST00000596131.1	AC114494.1	HCG1787699; Uncharacterized protein
chr21_+_43639211	0.18	ENST00000450121.1 ENST00000398449.3 ENST00000361802.2	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr11_-_93474645	0.18	ENST00000532455.1	TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr1_+_207494853	0.18	ENST00000367064.3 ENST00000367063.2 ENST00000391921.4 ENST00000367067.4 ENST00000314754.8 ENST00000367065.5 ENST00000391920.4 ENST00000367062.4 ENST00000343420.6	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr2_+_191045562	0.18	ENST00000340623.4	C2orf88	chromosome 2 open reading frame 88
chrX_-_72095622	0.18	ENST00000290273.5	DMRTC1	DMRT-like family C1
chrX_-_73512411	0.18	ENST00000602576.1 ENST00000429124.1	FTX	FTX transcript, XIST regulator (non-protein coding)
chr9_+_128024067	0.18	ENST00000461379.1 ENST00000394084.1 ENST00000394105.2 ENST00000470056.1 ENST00000394104.2 ENST00000265956.4 ENST00000394083.2 ENST00000495955.1 ENST00000467750.1 ENST00000297933.6	GAPVD1	GTPase activating protein and VPS9 domains 1
chr2_+_219433588	0.18	ENST00000295701.5	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr20_-_1472029	0.18	ENST00000359801.3	SIRPB2	signal-regulatory protein beta 2
chr7_+_39125365	0.18	ENST00000559001.1 ENST00000464276.2	POU6F2	POU class 6 homeobox 2
chrX_-_72095808	0.18	ENST00000373529.5	DMRTC1	DMRT-like family C1
chr3_-_42814708	0.17	ENST00000310232.6	CCDC13	coiled-coil domain containing 13
chr17_-_46667594	0.17	ENST00000476342.1 ENST00000460160.1 ENST00000472863.1	HOXB3	homeobox B3
chr6_-_31550192	0.17	ENST00000429299.2 ENST00000446745.2	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr3_-_107809816	0.17	ENST00000361309.5 ENST00000355354.7	CD47	CD47 molecule
chr10_+_73724123	0.17	ENST00000373115.4	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr16_+_29674540	0.17	ENST00000436527.1 ENST00000360121.3 ENST00000449759.1	SPN QPRT	sialophorin quinolinate phosphoribosyltransferase
chr18_+_55862622	0.17	ENST00000456173.2	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr12_+_104324112	0.16	ENST00000299767.5	HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr9_+_131799213	0.16	ENST00000358369.4 ENST00000406926.2 ENST00000277475.5 ENST00000450073.1	FAM73B	family with sequence similarity 73, member B
chr7_-_33080506	0.16	ENST00000381626.2 ENST00000409467.1 ENST00000449201.1	NT5C3A	5'-nucleotidase, cytosolic IIIA
chr17_+_61086917	0.16	ENST00000424789.2 ENST00000389520.4	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_+_24483338	0.16	ENST00000379162.4 ENST00000441463.2	PDK3	pyruvate dehydrogenase kinase, isozyme 3
chr19_-_52035044	0.16	ENST00000359982.4 ENST00000436458.1 ENST00000425629.3 ENST00000391797.3 ENST00000343300.4	SIGLEC6	sialic acid binding Ig-like lectin 6
chr2_+_160568978	0.16	ENST00000409175.1 ENST00000539065.1 ENST00000259050.4 ENST00000421037.1	MARCH7	membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr9_+_139847347	0.16	ENST00000371632.3	LCN12	lipocalin 12
chr2_-_190445499	0.16	ENST00000261024.2	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1
chr1_+_1551220	0.16	ENST00000378712.1	MIB2	mindbomb E3 ubiquitin protein ligase 2
chr7_+_93535817	0.16	ENST00000248572.5	GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr15_+_89631647	0.16	ENST00000569550.1 ENST00000565066.1 ENST00000565973.1	ABHD2	abhydrolase domain containing 2
chr3_+_186435137	0.16	ENST00000447445.1	KNG1	kininogen 1
chr10_+_76871229	0.16	ENST00000372690.3	SAMD8	sterile alpha motif domain containing 8
chr17_-_46667628	0.15	ENST00000498678.1	HOXB3	homeobox B3
chr11_+_3819049	0.15	ENST00000396986.2 ENST00000300730.6 ENST00000532535.1 ENST00000396993.4 ENST00000396991.2 ENST00000532523.1 ENST00000459679.1 ENST00000464261.1 ENST00000464906.2 ENST00000464441.1	PGAP2	post-GPI attachment to proteins 2
chr1_-_22263790	0.15	ENST00000374695.3	HSPG2	heparan sulfate proteoglycan 2
chr20_-_13765526	0.15	ENST00000202816.1	ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr10_+_76871353	0.15	ENST00000542569.1	SAMD8	sterile alpha motif domain containing 8
chr15_-_82555000	0.15	ENST00000557844.1 ENST00000359445.3 ENST00000268206.7	EFTUD1	elongation factor Tu GTP binding domain containing 1
chr17_+_74734052	0.15	ENST00000590514.1	MFSD11	major facilitator superfamily domain containing 11
chr1_+_16174280	0.15	ENST00000375759.3	SPEN	spen family transcriptional repressor
chr4_+_140222609	0.15	ENST00000296543.5 ENST00000398947.1	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_-_156571254	0.15	ENST00000438976.2 ENST00000334588.7 ENST00000368232.4 ENST00000415314.2	GPATCH4	G patch domain containing 4
chr3_-_149051444	0.15	ENST00000296059.2	TM4SF18	transmembrane 4 L six family member 18
chr1_-_224033596	0.15	ENST00000391878.2 ENST00000343537.7	TP53BP2	tumor protein p53 binding protein, 2
chr21_+_34398153	0.15	ENST00000382357.3 ENST00000430860.1 ENST00000333337.3	OLIG2	oligodendrocyte lineage transcription factor 2
chr20_+_44746939	0.15	ENST00000372276.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr1_+_16083154	0.15	ENST00000375771.1	FBLIM1	filamin binding LIM protein 1
chr2_+_113403434	0.15	ENST00000272542.3	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr9_-_34397800	0.15	ENST00000297623.2	C9orf24	chromosome 9 open reading frame 24
chr20_+_42544782	0.15	ENST00000423191.2 ENST00000372999.1	TOX2	TOX high mobility group box family member 2
chr11_+_20620946	0.14	ENST00000525748.1	SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 5
chr1_+_236958554	0.14	ENST00000366577.5 ENST00000418145.2	MTR	5-methyltetrahydrofolate-homocysteine methyltransferase
chr10_+_76871454	0.14	ENST00000372687.4	SAMD8	sterile alpha motif domain containing 8
chr8_-_68658578	0.14	ENST00000518549.1 ENST00000297770.4 ENST00000297769.4	CPA6	carboxypeptidase A6
chr19_-_13947099	0.14	ENST00000587762.1	MIR24-2	microRNA 24-2
chr14_+_23938891	0.14	ENST00000408901.3 ENST00000397154.3 ENST00000555128.1	NGDN	neuroguidin, EIF4E binding protein
chr6_+_44310421	0.14	ENST00000288390.2	SPATS1	spermatogenesis associated, serine-rich 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0042938	dipeptide transport(GO:0042938)
0.3	1.3	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.2	0.6	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.2	0.6	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2	0.7	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.2	0.5	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2	1.4	GO:0015705	iodide transport(GO:0015705)
0.1	1.2	GO:0061591	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1	0.6	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.1	0.4	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	0.6	GO:0045918	positive regulation of interleukin-23 production(GO:0032747) negative regulation of cytolysis(GO:0045918)
0.1	0.9	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1	0.8	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	0.4	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.1	0.5	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1	0.4	GO:0003164	His-Purkinje system development(GO:0003164)
0.1	0.2	GO:2001037	tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1	0.9	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	0.1	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
0.1	0.4	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.1	0.8	GO:0032119	sequestering of zinc ion(GO:0032119)
0.1	0.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.2	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1	0.5	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.2	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1	0.4	GO:0034436	glycoprotein transport(GO:0034436)
0.1	0.1	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1	0.2	GO:0031247	actin rod assembly(GO:0031247)
0.1	1.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.3	GO:0051941	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1	0.2	GO:0070839	divalent metal ion export(GO:0070839)
0.1	1.0	GO:0090179	planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1	0.2	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	0.2	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.6	GO:0002934	desmosome organization(GO:0002934)
0.0	0.3	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.2	GO:0070352	positive regulation of white fat cell proliferation(GO:0070352)
0.0	0.5	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.1	GO:0001694	histamine biosynthetic process(GO:0001694)
0.0	0.5	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.4	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0	0.2	GO:0048867	ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0	0.4	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0	0.2	GO:0001808	negative regulation of type IV hypersensitivity(GO:0001808)
0.0	0.2	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0	0.3	GO:0021546	rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.2	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0	0.2	GO:1902162	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0	0.7	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0033590	response to cobalamin(GO:0033590)
0.0	0.6	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.2	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.4	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.2	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.1	GO:0035281	pre-miRNA export from nucleus(GO:0035281)
0.0	0.1	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.0	0.7	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.2	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.0	0.1	GO:2000584	regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0	0.2	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:0006021	inositol biosynthetic process(GO:0006021)
0.0	0.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.4	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.2	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.0	GO:0010165	response to X-ray(GO:0010165)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.3	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.3	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.0	0.1	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:0060127	pulmonary myocardium development(GO:0003350) subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0	0.1	GO:0007518	myoblast fate determination(GO:0007518)
0.0	0.3	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0071503	response to heparin(GO:0071503)
0.0	0.1	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0	0.1	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.1	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.4	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0019427	acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0	0.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.2	GO:0002517	T cell tolerance induction(GO:0002517)
0.0	0.4	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.4	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.1	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.3	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.6	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0	0.2	GO:0002643	regulation of tolerance induction(GO:0002643)
0.0	0.1	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.1	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:1902715	secretory granule localization(GO:0032252) positive regulation of natural killer cell differentiation(GO:0032825) positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.0	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.0	0.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.2	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.4	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.0	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0	0.2	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.2	GO:0050650	chondroitin sulfate biosynthetic process(GO:0030206) chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.0	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.0	0.1	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0097232	lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1	0.6	GO:0061689	tricellular tight junction(GO:0061689)
0.1	0.2	GO:0005668	RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1	0.4	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0	1.7	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.6	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.5	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.4	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.3	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	1.1	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.5	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.4	GO:0042101	T cell receptor complex(GO:0042101)
0.0	1.3	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.0	GO:0034707	chloride channel complex(GO:0034707)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.2	1.4	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	1.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.1	1.0	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.8	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	2.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.6	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.4	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1	0.4	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.1	0.6	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.5	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.5	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	0.4	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.7	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.5	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	0.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.1	0.5	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.4	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	1.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.5	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0090631	pre-miRNA transporter activity(GO:0090631)
0.0	0.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.2	GO:0008665	2'-phosphotransferase activity(GO:0008665)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.3	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.6	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.2	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.6	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.3	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	0.4	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.7	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.2	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.0	0.2	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.0	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	0.1	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.8	GO:0008009	chemokine activity(GO:0008009)
0.0	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	2.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.4	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	1.3	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.8	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.0	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.7	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.6	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.8	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.9	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	1.2	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	1.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions