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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for XBP1

Z-value: 1.12

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Transcription factors associated with XBP1

Gene Symbol Gene ID Gene Info
XBP1
ENSG00000100219.12 XBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
XBP1hg19_v2_chr22_-_29196030_29196121,
hg19_v2_chr22_-_29196546_29196585		-0.147.4e-01Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_94023873 5.94 ENST00000297268.6
 COL1A2
 collagen, type I, alpha 2
chr5_+_119799927 2.26 ENST00000407149.2
ENST00000379551.2
 PRR16
 proline rich 16
chr5_-_9546180 2.16 ENST00000382496.5
 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr5_-_121413974 1.34 ENST00000231004.4
 LOX
 lysyl oxidase
chr22_+_38864041 1.24 ENST00000216014.4
ENST00000409006.3
 KDELR3
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr10_+_89419370 1.21 ENST00000361175.4
ENST00000456849.1
 PAPSS2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr8_+_104384616 1.05 ENST00000520337.1
 CTHRC1
 collagen triple helix repeat containing 1
chr7_-_19157248 0.99 ENST00000242261.5
 TWIST1
 twist family bHLH transcription factor 1
chr14_+_100259666 0.85 ENST00000262233.6
ENST00000334192.4
 EML1
 echinoderm microtubule associated protein like 1
chr5_+_9546306 0.84 ENST00000508179.1
 SNHG18
 small nucleolar RNA host gene 18 (non-protein coding)
chr22_+_46476192 0.73 ENST00000443490.1
 FLJ27365
 hsa-mir-4763
chr6_+_132891461 0.72 ENST00000275198.1
 TAAR6
 trace amine associated receptor 6
chr3_+_105086056 0.59 ENST00000472644.2
 ALCAM
 activated leukocyte cell adhesion molecule
chr20_+_44044717 0.58 ENST00000279036.6
ENST00000279035.9
ENST00000372689.5
ENST00000545755.1
ENST00000341555.5
ENST00000535404.1
ENST00000543458.2
ENST00000432270.1
 PIGT
 phosphatidylinositol glycan anchor biosynthesis, class T
chrX_+_9431324 0.56 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X
 transducin (beta)-like 1X-linked
chr6_+_132129151 0.54 ENST00000360971.2
 ENPP1
 ectonucleotide pyrophosphatase/phosphodiesterase 1
chr17_+_64298944 0.52 ENST00000413366.3
 PRKCA
 protein kinase C, alpha
chr6_+_83903061 0.51 ENST00000369724.4
ENST00000539997.1
 RWDD2A
 RWD domain containing 2A
chr12_+_99038919 0.49 ENST00000551964.1
 APAF1
 apoptotic peptidase activating factor 1
chr3_-_105588231 0.48 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_-_99038732 0.48 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
 IKBIP
 IKBKB interacting protein
chr12_+_7053172 0.46 ENST00000229281.5
 C12orf57
 chromosome 12 open reading frame 57
chr12_+_7052974 0.46 ENST00000544681.1
ENST00000537087.1
 C12orf57
 chromosome 12 open reading frame 57
chr6_-_83902933 0.46 ENST00000512866.1
ENST00000510258.1
ENST00000503094.1
ENST00000283977.4
ENST00000513973.1
ENST00000508748.1
 PGM3
 phosphoglucomutase 3
chr22_-_31503490 0.45 ENST00000400299.2
 SELM
 Selenoprotein M
chr1_-_145039949 0.45 ENST00000313382.9
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr17_-_8059638 0.45 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
 PER1
 period circadian clock 1
chr10_-_128077024 0.44 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
 ADAM12
 ADAM metallopeptidase domain 12
chr7_+_100547156 0.43 ENST00000379458.4
 MUC3A
 Protein LOC100131514
chr16_-_73082274 0.42 ENST00000268489.5
 ZFHX3
 zinc finger homeobox 3
chr12_+_7053228 0.41 ENST00000540506.2
 C12orf57
 chromosome 12 open reading frame 57
chr7_-_27183263 0.40 ENST00000222726.3
 HOXA5
 homeobox A5
chr22_-_20850128 0.40 ENST00000328879.4
 KLHL22
 kelch-like family member 22
chr12_+_99038998 0.40 ENST00000359972.2
ENST00000357310.1
ENST00000339433.3
ENST00000333991.1
 APAF1
 apoptotic peptidase activating factor 1
chr17_-_42276574 0.38 ENST00000589805.1
 ATXN7L3
 ataxin 7-like 3
chr6_+_33168637 0.37 ENST00000374677.3
 SLC39A7
 solute carrier family 39 (zinc transporter), member 7
chr20_+_25228669 0.36 ENST00000216962.4
 PYGB
 phosphorylase, glycogen; brain
chr12_+_107349497 0.36 ENST00000548125.1
ENST00000280756.4
 C12orf23
 chromosome 12 open reading frame 23
chr6_+_33168597 0.36 ENST00000374675.3
 SLC39A7
 solute carrier family 39 (zinc transporter), member 7
chr5_+_154238149 0.36 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr1_+_101361782 0.35 ENST00000357650.4
 SLC30A7
 solute carrier family 30 (zinc transporter), member 7
chr3_-_105587879 0.35 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr9_+_35732312 0.35 ENST00000353704.2
 CREB3
 cAMP responsive element binding protein 3
chr5_+_154238042 0.34 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr12_-_56123444 0.34 ENST00000546457.1
ENST00000549117.1
 CD63
 CD63 molecule
chr20_-_33680588 0.34 ENST00000451813.2
ENST00000432634.2
 TRPC4AP
 transient receptor potential cation channel, subfamily C, member 4 associated protein
chr22_-_20850070 0.34 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
 KLHL22
 kelch-like family member 22
chr5_+_126853301 0.33 ENST00000296666.8
ENST00000442138.2
ENST00000512635.2
 PRRC1
 proline-rich coiled-coil 1
chr10_-_22292675 0.32 ENST00000376946.1
 DNAJC1
 DnaJ (Hsp40) homolog, subfamily C, member 1
chr3_+_171758344 0.32 ENST00000336824.4
ENST00000423424.1
 FNDC3B
 fibronectin type III domain containing 3B
chr11_+_69455855 0.32 ENST00000227507.2
ENST00000536559.1
 CCND1
 cyclin D1
chr5_-_115177496 0.31 ENST00000274459.4
ENST00000509910.1
 ATG12
 autophagy related 12
chr1_-_144932316 0.31 ENST00000313431.9
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr4_-_119757239 0.30 ENST00000280551.6
 SEC24D
 SEC24 family member D
chr5_-_93447333 0.30 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
 FAM172A
 family with sequence similarity 172, member A
chr19_-_58459039 0.30 ENST00000282308.3
ENST00000598928.1
 ZNF256
 zinc finger protein 256
chr5_-_176730676 0.28 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
 RAB24
 RAB24, member RAS oncogene family
chr15_-_60690163 0.28 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
 ANXA2
 annexin A2
chr13_+_35516390 0.28 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
 NBEA
 neurobeachin
chr3_-_183543301 0.27 ENST00000318631.3
ENST00000431348.1
 MAP6D1
 MAP6 domain containing 1
chr9_+_126777676 0.26 ENST00000488674.2
 LHX2
 LIM homeobox 2
chr4_-_119757322 0.26 ENST00000379735.5
 SEC24D
 SEC24 family member D
chr20_-_17662705 0.25 ENST00000455029.2
 RRBP1
 ribosome binding protein 1
chr8_-_124553437 0.25 ENST00000517956.1
ENST00000443022.2
 FBXO32
 F-box protein 32
chr2_+_242254507 0.25 ENST00000391973.2
 SEPT2
 septin 2
chr5_-_108745689 0.25 ENST00000361189.2
 PJA2
 praja ring finger 2, E3 ubiquitin protein ligase
chr8_-_38126675 0.24 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
 PPAPDC1B
 phosphatidic acid phosphatase type 2 domain containing 1B
chr1_-_144932014 0.24 ENST00000529945.1
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr1_+_6845384 0.24 ENST00000303635.7
 CAMTA1
 calmodulin binding transcription activator 1
chr16_-_30546141 0.24 ENST00000535210.1
ENST00000395094.3
 ZNF747
 zinc finger protein 747
chr11_+_17298255 0.24 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
 NUCB2
 nucleobindin 2
chr20_-_17662878 0.23 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
 RRBP1
 ribosome binding protein 1
chr5_-_171881362 0.23 ENST00000519643.1
 SH3PXD2B
 SH3 and PX domains 2B
chr6_+_132873832 0.23 ENST00000275200.1
 TAAR8
 trace amine associated receptor 8
chr12_-_91348949 0.23 ENST00000358859.2
 CCER1
 coiled-coil glutamate-rich protein 1
chr15_-_43622736 0.23 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
 LCMT2
 leucine carboxyl methyltransferase 2
chr5_+_154237778 0.22 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr1_+_6845578 0.22 ENST00000467404.2
ENST00000439411.2
 CAMTA1
 calmodulin binding transcription activator 1
chr21_+_45138941 0.22 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
 PDXK
 pyridoxal (pyridoxine, vitamin B6) kinase
chr22_-_43253189 0.22 ENST00000437119.2
ENST00000429508.2
ENST00000454099.1
ENST00000263245.5
 ARFGAP3
 ADP-ribosylation factor GTPase activating protein 3
chr11_+_17298297 0.21 ENST00000529010.1
 NUCB2
 nucleobindin 2
chr17_+_73106035 0.21 ENST00000581078.1
ENST00000582136.1
ENST00000245543.1
 ARMC7
 armadillo repeat containing 7
chr9_+_37079888 0.21 ENST00000429493.1
ENST00000593237.1
ENST00000588557.1
ENST00000430809.1
ENST00000592157.1
 RP11-220I1.1
 RP11-220I1.1
chr5_+_154238096 0.20 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr4_+_56262115 0.20 ENST00000506198.1
ENST00000381334.5
ENST00000542052.1
 TMEM165
 transmembrane protein 165
chr11_-_102576537 0.20 ENST00000260229.4
 MMP27
 matrix metallopeptidase 27
chr12_+_56624436 0.19 ENST00000266980.4
ENST00000437277.1
 SLC39A5
 solute carrier family 39 (zinc transporter), member 5
chr2_-_15701422 0.19 ENST00000441750.1
ENST00000281513.5
 NBAS
 neuroblastoma amplified sequence
chr1_+_6845497 0.19 ENST00000473578.1
ENST00000557126.1
 CAMTA1
 calmodulin binding transcription activator 1
chr17_-_40575535 0.19 ENST00000357037.5
 PTRF
 polymerase I and transcript release factor
chr1_+_249200395 0.19 ENST00000355360.4
ENST00000329291.5
ENST00000539153.1
 PGBD2
 piggyBac transposable element derived 2
chr2_-_33824382 0.18 ENST00000238823.8
 FAM98A
 family with sequence similarity 98, member A
chr6_-_90062543 0.18 ENST00000435041.2
 UBE2J1
 ubiquitin-conjugating enzyme E2, J1
chr9_-_34523027 0.17 ENST00000399775.2
 ENHO
 energy homeostasis associated
chr4_+_76649797 0.17 ENST00000538159.1
ENST00000514213.2
 USO1
 USO1 vesicle transport factor
chr1_+_26758790 0.16 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
 DHDDS
 dehydrodolichyl diphosphate synthase
chr7_-_12443501 0.16 ENST00000275358.3
 VWDE
 von Willebrand factor D and EGF domains
chr2_-_33824336 0.16 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
 FAM98A
 family with sequence similarity 98, member A
chr14_-_24664776 0.16 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
 TM9SF1
 transmembrane 9 superfamily member 1
chr1_+_145575980 0.16 ENST00000393045.2
 PIAS3
 protein inhibitor of activated STAT, 3
chr20_-_8000426 0.16 ENST00000527925.1
ENST00000246024.2
 TMX4
 thioredoxin-related transmembrane protein 4
chr1_+_145576007 0.16 ENST00000369298.1
 PIAS3
 protein inhibitor of activated STAT, 3
chr4_+_26322185 0.15 ENST00000361572.6
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr2_+_242254679 0.15 ENST00000428282.1
ENST00000360051.3
 SEPT2
 septin 2
chr19_+_36606654 0.15 ENST00000588385.1
ENST00000585746.1
 TBCB
 tubulin folding cofactor B
chr2_+_85132749 0.15 ENST00000233143.4
 TMSB10
 thymosin beta 10
chr15_-_60690932 0.15 ENST00000559818.1
 ANXA2
 annexin A2
chr9_-_35732362 0.14 ENST00000314888.9
ENST00000540444.1
 TLN1
 talin 1
chr2_-_69614373 0.14 ENST00000361060.5
ENST00000357308.4
 GFPT1
 glutamine--fructose-6-phosphate transaminase 1
chr18_-_34408902 0.14 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
 TPGS2
 tubulin polyglutamylase complex subunit 2
chr12_-_133405288 0.14 ENST00000204726.3
 GOLGA3
 golgin A3
chr14_-_24664540 0.14 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
 TM9SF1
 transmembrane 9 superfamily member 1
chr5_-_171881491 0.14 ENST00000311601.5
 SH3PXD2B
 SH3 and PX domains 2B
chr1_+_21835858 0.14 ENST00000539907.1
ENST00000540617.1
ENST00000374840.3
 ALPL
 alkaline phosphatase, liver/bone/kidney
chr3_-_132378919 0.14 ENST00000355458.3
 ACAD11
 acyl-CoA dehydrogenase family, member 11
chr11_+_32605350 0.14 ENST00000531120.1
ENST00000524896.1
ENST00000323213.5
 EIF3M
 eukaryotic translation initiation factor 3, subunit M
chr12_+_58120044 0.13 ENST00000542466.2
 AGAP2-AS1
 AGAP2 antisense RNA 1
chr4_+_40058411 0.13 ENST00000261435.6
ENST00000515550.1
 N4BP2
 NEDD4 binding protein 2
chr1_-_22109682 0.13 ENST00000400301.1
ENST00000532737.1
 USP48
 ubiquitin specific peptidase 48
chr14_+_50087468 0.13 ENST00000305386.2
 MGAT2
 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_+_55477711 0.13 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
 NLRP2
 NLR family, pyrin domain containing 2
chr9_+_114393634 0.13 ENST00000556107.1
ENST00000374294.3
 DNAJC25
DNAJC25-GNG10
 DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr14_-_92506371 0.13 ENST00000267622.4
 TRIP11
 thyroid hormone receptor interactor 11
chr4_+_26322409 0.13 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr3_+_50284321 0.12 ENST00000451956.1
 GNAI2
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr2_-_242254595 0.11 ENST00000441124.1
ENST00000391976.2
 HDLBP
 high density lipoprotein binding protein
chr3_-_28390415 0.11 ENST00000414162.1
ENST00000420543.2
 AZI2
 5-azacytidine induced 2
chr19_+_50354462 0.11 ENST00000601675.1
 PTOV1
 prostate tumor overexpressed 1
chr11_-_207221 0.11 ENST00000486280.1
ENST00000332865.6
ENST00000529614.2
ENST00000325147.9
ENST00000410108.1
ENST00000382762.3
 BET1L
 Bet1 golgi vesicular membrane trafficking protein-like
chr18_+_34409069 0.11 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
 KIAA1328
 KIAA1328
chr19_+_16187816 0.10 ENST00000588410.1
 TPM4
 tropomyosin 4
chr9_+_15553055 0.10 ENST00000380701.3
 CCDC171
 coiled-coil domain containing 171
chr11_-_62599505 0.10 ENST00000377897.4
ENST00000394690.1
ENST00000541317.1
ENST00000294179.3
 STX5
 syntaxin 5
chr1_+_87170577 0.10 ENST00000482504.1
 SH3GLB1
 SH3-domain GRB2-like endophilin B1
chr11_-_66056596 0.10 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
 YIF1A
 Yip1 interacting factor homolog A (S. cerevisiae)
chr19_-_54618650 0.10 ENST00000391757.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr19_+_50354430 0.09 ENST00000599732.1
 PTOV1
 prostate tumor overexpressed 1
chr19_-_54619006 0.09 ENST00000391759.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr6_+_63921351 0.09 ENST00000370659.1
 FKBP1C
 FK506 binding protein 1C
chr1_-_155145721 0.09 ENST00000295682.4
 KRTCAP2
 keratinocyte associated protein 2
chr2_-_118771701 0.09 ENST00000376300.2
ENST00000319432.5
 CCDC93
 coiled-coil domain containing 93
chr12_-_133405409 0.09 ENST00000545875.1
ENST00000456883.2
 GOLGA3
 golgin A3
chr19_+_50354393 0.09 ENST00000391842.1
 PTOV1
 prostate tumor overexpressed 1
chr1_-_22109484 0.09 ENST00000529637.1
 USP48
 ubiquitin specific peptidase 48
chr19_+_49468558 0.09 ENST00000331825.6
 FTL
 ferritin, light polypeptide
chr19_-_19030157 0.09 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
 COPE
 coatomer protein complex, subunit epsilon
chr14_+_102430855 0.09 ENST00000360184.4
 DYNC1H1
 dynein, cytoplasmic 1, heavy chain 1
chr3_-_10362725 0.09 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
 SEC13
 SEC13 homolog (S. cerevisiae)
chr3_-_28390298 0.09 ENST00000457172.1
 AZI2
 5-azacytidine induced 2
chr7_+_128379346 0.08 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
 CALU
 calumenin
chr12_-_109125285 0.08 ENST00000552871.1
ENST00000261401.3
 CORO1C
 coronin, actin binding protein, 1C
chr5_+_112196919 0.08 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
 SRP19
 signal recognition particle 19kDa
chr3_+_127771212 0.08 ENST00000243253.3
ENST00000481210.1
 SEC61A1
 Sec61 alpha 1 subunit (S. cerevisiae)
chr4_-_83351005 0.08 ENST00000295470.5
 HNRNPDL
 heterogeneous nuclear ribonucleoprotein D-like
chrX_+_153627231 0.08 ENST00000406022.2
 RPL10
 ribosomal protein L10
chr3_-_149688502 0.08 ENST00000481767.1
ENST00000475518.1
 PFN2
 profilin 2
chrX_-_41782249 0.07 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
 CASK
 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr11_-_64646086 0.07 ENST00000320631.3
 EHD1
 EH-domain containing 1
chr19_-_22379753 0.07 ENST00000397121.2
 ZNF676
 zinc finger protein 676
chr6_-_7313381 0.07 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
 SSR1
 signal sequence receptor, alpha
chr14_+_39736299 0.07 ENST00000341502.5
ENST00000396158.2
ENST00000280083.3
 CTAGE5
 CTAGE family, member 5
chr21_+_45705752 0.07 ENST00000291582.5
 AIRE
 autoimmune regulator
chr7_+_128379449 0.07 ENST00000479257.1
 CALU
 calumenin
chr3_-_149688896 0.07 ENST00000239940.7
 PFN2
 profilin 2
chr11_-_66056478 0.07 ENST00000431556.2
ENST00000528575.1
 YIF1A
 Yip1 interacting factor homolog A (S. cerevisiae)
chr11_+_47430133 0.06 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
 SLC39A13
 solute carrier family 39 (zinc transporter), member 13
chr16_-_75569068 0.06 ENST00000336257.3
ENST00000565039.1
 CHST5
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr1_+_222791417 0.06 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
 MIA3
 melanoma inhibitory activity family, member 3
chr17_+_46048376 0.06 ENST00000338399.4
 CDK5RAP3
 CDK5 regulatory subunit associated protein 3
chr10_-_30348439 0.06 ENST00000375377.1
 KIAA1462
 KIAA1462
chr9_+_101984577 0.06 ENST00000223641.4
 SEC61B
 Sec61 beta subunit
chr4_-_47916543 0.05 ENST00000507489.1
 NFXL1
 nuclear transcription factor, X-box binding-like 1
chr2_-_20251744 0.05 ENST00000175091.4
 LAPTM4A
 lysosomal protein transmembrane 4 alpha
chr4_-_46392290 0.05 ENST00000515082.1
 GABRA2
 gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr19_+_50353944 0.05 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
 PTOV1
 prostate tumor overexpressed 1
chr12_+_56862301 0.05 ENST00000338146.5
 SPRYD4
 SPRY domain containing 4
chr18_-_34409116 0.05 ENST00000334295.4
 TPGS2
 tubulin polyglutamylase complex subunit 2
chr15_-_75165651 0.05 ENST00000562363.1
ENST00000564529.1
ENST00000268099.9
 SCAMP2
 secretory carrier membrane protein 2
chr4_-_47916613 0.05 ENST00000381538.3
ENST00000329043.3
 NFXL1
 nuclear transcription factor, X-box binding-like 1
chr9_+_114393581 0.04 ENST00000313525.3
 DNAJC25
 DnaJ (Hsp40) homolog, subfamily C , member 25
chr1_-_119683251 0.04 ENST00000369426.5
ENST00000235521.4
 WARS2
 tryptophanyl tRNA synthetase 2, mitochondrial
chr2_+_241508039 0.04 ENST00000270357.4
 RNPEPL1
 arginyl aminopeptidase (aminopeptidase B)-like 1
chr18_-_34408802 0.04 ENST00000590842.1
 TPGS2
 tubulin polyglutamylase complex subunit 2
chr4_+_141445311 0.03 ENST00000323570.3
ENST00000511887.2
 ELMOD2
 ELMO/CED-12 domain containing 2
chr16_+_2083265 0.03 ENST00000565855.1
ENST00000566198.1
 SLC9A3R2
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr12_+_48722763 0.03 ENST00000335017.1
 H1FNT
 H1 histone family, member N, testis-specific
chr17_+_7184986 0.03 ENST00000317370.8
ENST00000571308.1
 SLC2A4
 solute carrier family 2 (facilitated glucose transporter), member 4
chr17_+_72199721 0.03 ENST00000439590.2
ENST00000311111.6
ENST00000584577.1
ENST00000534490.1
ENST00000528433.2
ENST00000533498.1
 RPL38
 ribosomal protein L38
chr14_+_31091511 0.03 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
 SCFD1
 sec1 family domain containing 1
chr2_+_27255806 0.03 ENST00000238788.9
ENST00000404032.3
 TMEM214
 transmembrane protein 214
chr6_+_43968306 0.03 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
 C6orf223
 chromosome 6 open reading frame 223
chr18_-_34408693 0.03 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
 TPGS2
 tubulin polyglutamylase complex subunit 2
chr3_+_132378741 0.03 ENST00000493720.2
 UBA5
 ubiquitin-like modifier activating enzyme 5
chr7_+_6522922 0.03 ENST00000601673.1
 FLJ20306
 CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein
chr1_+_228270361 0.03 ENST00000272102.5
ENST00000540651.1
 ARF1
 ADP-ribosylation factor 1
chr19_+_47104553 0.02 ENST00000598871.1
ENST00000594523.1
 CALM3
 calmodulin 3 (phosphorylase kinase, delta)
chr6_-_33168391 0.02 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
 RXRB
 retinoid X receptor, beta
chr4_+_128982430 0.02 ENST00000512292.1
ENST00000508819.1
 LARP1B
 La ribonucleoprotein domain family, member 1B
chr3_-_128369643 0.02 ENST00000296255.3
 RPN1
 ribophorin I
chrX_+_153060090 0.02 ENST00000370086.3
ENST00000370085.3
 SSR4
 signal sequence receptor, delta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.9 GO:0043589 skin morphogenesis(GO:0043589)
0.3 1.0 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.3 1.2 GO:0000103 sulfate assimilation(GO:0000103)
0.2 1.3 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 0.5 GO:0061110 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.2 2.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842) negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 1.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.4 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1 2.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:0060435 bronchiole development(GO:0060435)
0.1 0.9 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.6 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.8 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:2000410 tolerance induction dependent upon immune response(GO:0002461) regulation of thymocyte migration(GO:2000410)
0.0 0.7 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.3 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.9 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 1.2 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 5.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.5 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.2 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.2 GO:0031403 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC