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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZIC1

Z-value: 0.61

Motif logo

Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ENSG00000152977.5 ZIC1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg19_v2_chr3_+_147127142_147127171-0.611.1e-01Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_120685608 1.41 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_+_14113592 1.37 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr13_+_102104980 1.27 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr13_+_102104952 1.13 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr19_-_3028354 1.10 ENST00000586422.1
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr1_+_89990431 0.99 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr12_-_15038779 0.88 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr22_-_24622080 0.80 ENST00000425408.1
GGT5
gamma-glutamyltransferase 5
chr17_-_53809473 0.67 ENST00000575734.1
TMEM100
transmembrane protein 100
chr11_+_67777751 0.53 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr17_-_43045439 0.53 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr2_-_99552620 0.50 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L
KIAA1211-like
chr11_-_2160180 0.48 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_-_87804815 0.47 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr15_+_63340553 0.47 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr11_-_74022658 0.46 ENST00000427714.2
ENST00000331597.4
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr22_+_44319648 0.46 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr16_+_30996502 0.45 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr22_+_44319619 0.44 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr3_-_58563094 0.43 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr6_-_35656685 0.42 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr2_+_46769798 0.39 ENST00000238738.4
RHOQ
ras homolog family member Q
chr6_-_35656712 0.39 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chr10_-_49701686 0.38 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr5_-_64920115 0.36 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr6_+_132891461 0.36 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr10_-_64028466 0.32 ENST00000395265.1
ENST00000373789.3
ENST00000395260.3
RTKN2
rhotekin 2
chr11_-_134123142 0.32 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr3_+_141105705 0.31 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr1_+_65775204 0.30 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_+_54951679 0.27 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr17_-_9940058 0.26 ENST00000585266.1
GAS7
growth arrest-specific 7
chr10_-_33624002 0.26 ENST00000432372.2
NRP1
neuropilin 1
chr17_-_18945798 0.24 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr4_-_7941596 0.24 ENST00000420658.1
ENST00000358461.2
AFAP1
actin filament associated protein 1
chr10_-_33623826 0.23 ENST00000374867.2
NRP1
neuropilin 1
chr17_-_39183452 0.22 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr11_-_73309228 0.22 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr21_+_46066331 0.21 ENST00000334670.8
KRTAP10-11
keratin associated protein 10-11
chr17_-_39222131 0.21 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chrX_+_77166172 0.21 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr10_-_33623564 0.20 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr4_-_186733363 0.20 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr19_-_58609570 0.20 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
ZSCAN18
zinc finger and SCAN domain containing 18
chr7_-_100493744 0.19 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr2_+_79347577 0.19 ENST00000233735.1
REG1A
regenerating islet-derived 1 alpha
chr21_+_45148735 0.19 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chrX_+_18725758 0.19 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr6_-_34216766 0.18 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
C6orf1
chromosome 6 open reading frame 1
chr17_+_75450075 0.18 ENST00000592951.1
SEPT9
septin 9
chrX_+_153770421 0.17 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr17_-_39191107 0.17 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr12_-_11002063 0.17 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr3_+_148847371 0.16 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr1_-_1711508 0.16 ENST00000378625.1
NADK
NAD kinase
chr4_+_2627159 0.16 ENST00000382839.3
ENST00000324666.5
ENST00000545951.1
ENST00000502458.1
ENST00000505311.1
FAM193A
family with sequence similarity 193, member A
chr14_-_50999190 0.16 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr17_-_6947225 0.16 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11
solute carrier family 16, member 11
chr1_+_61869748 0.15 ENST00000357977.5
NFIA
nuclear factor I/A
chr16_+_771663 0.15 ENST00000568916.1
FAM173A
family with sequence similarity 173, member A
chr3_+_126243126 0.15 ENST00000319340.2
CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr19_+_42364460 0.15 ENST00000593863.1
RPS19
ribosomal protein S19
chr19_+_10196781 0.15 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr19_+_45409011 0.14 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr2_+_169926047 0.14 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr22_+_22599075 0.14 ENST00000403807.3
VPREB1
pre-B lymphocyte 1
chr4_-_89444883 0.14 ENST00000273968.4
PYURF
PIGY upstream reading frame
chr16_-_745946 0.14 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr9_-_123639600 0.14 ENST00000373896.3
PHF19
PHD finger protein 19
chr6_+_31540056 0.13 ENST00000418386.2
LTA
lymphotoxin alpha
chr19_+_37095719 0.13 ENST00000423582.1
ZNF382
zinc finger protein 382
chr14_+_55033815 0.13 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr1_-_113249678 0.12 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr1_-_113249734 0.12 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr1_-_113249948 0.12 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chrX_+_52926322 0.12 ENST00000430150.2
ENST00000452021.2
ENST00000412319.1
FAM156B
family with sequence similarity 156, member B
chr11_+_64002292 0.12 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr17_+_8243154 0.12 ENST00000328248.2
ENST00000584943.1
ODF4
outer dense fiber of sperm tails 4
chr1_+_161087873 0.12 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1
nitrilase 1
chr11_+_64001962 0.11 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr22_-_23922410 0.11 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr11_+_120207787 0.11 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr17_-_76274572 0.11 ENST00000374945.1
RP11-219G17.4
RP11-219G17.4
chr19_+_41509851 0.11 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr17_-_56609302 0.11 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
SEPT4
septin 4
chr19_+_13135790 0.10 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_-_755819 0.10 ENST00000397621.1
FBXL16
F-box and leucine-rich repeat protein 16
chr19_+_10563567 0.10 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_95699704 0.10 ENST00000370202.4
RWDD3
RWD domain containing 3
chr11_-_46142615 0.10 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr21_+_31768348 0.10 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr4_-_175750364 0.10 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr10_+_21823079 0.09 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr7_-_3214287 0.09 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr14_+_36295638 0.09 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr10_+_21823243 0.09 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr11_-_62689046 0.08 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr12_+_27091426 0.08 ENST00000546072.1
ENST00000327214.5
FGFR1OP2
FGFR1 oncogene partner 2
chr1_+_2487800 0.08 ENST00000355716.4
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr17_+_18280976 0.08 ENST00000399134.4
EVPLL
envoplakin-like
chr22_-_23922448 0.08 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr7_-_102789629 0.08 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr1_-_231004220 0.08 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr11_+_15095108 0.08 ENST00000324229.6
ENST00000533448.1
CALCB
calcitonin-related polypeptide beta
chr6_+_31949801 0.08 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr17_+_40913210 0.07 ENST00000253796.5
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr14_+_36295504 0.07 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr19_+_46806856 0.07 ENST00000300862.3
HIF3A
hypoxia inducible factor 3, alpha subunit
chr1_-_20446020 0.07 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr16_+_28858004 0.07 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr9_-_123639445 0.07 ENST00000312189.6
PHF19
PHD finger protein 19
chr17_-_3794021 0.07 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr4_-_109090106 0.07 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr4_-_109089573 0.07 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr5_+_140514782 0.07 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr1_+_16348497 0.06 ENST00000439316.2
CLCNKA
chloride channel, voltage-sensitive Ka
chr8_+_21946681 0.06 ENST00000289921.7
FAM160B2
family with sequence similarity 160, member B2
chr12_+_27091316 0.06 ENST00000229395.3
FGFR1OP2
FGFR1 oncogene partner 2
chr11_+_65779283 0.06 ENST00000312134.2
CST6
cystatin E/M
chr9_+_35792151 0.06 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr5_+_112312399 0.06 ENST00000515408.1
ENST00000513585.1
DCP2
decapping mRNA 2
chr4_-_66536057 0.06 ENST00000273854.3
EPHA5
EPH receptor A5
chr21_-_46012386 0.06 ENST00000400368.1
KRTAP10-6
keratin associated protein 10-6
chr17_-_39203519 0.05 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr10_+_118350468 0.05 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr12_-_59314246 0.05 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr20_+_61924532 0.05 ENST00000358894.6
ENST00000326996.6
ENST00000435874.1
COL20A1
collagen, type XX, alpha 1
chr17_-_4464081 0.05 ENST00000574154.1
GGT6
gamma-glutamyltransferase 6
chr7_+_150264365 0.05 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr16_-_11485922 0.05 ENST00000599216.1
CTD-3088G3.8
Protein LOC388210
chr15_-_71407806 0.05 ENST00000566432.1
ENST00000567117.1
CT62
cancer/testis antigen 62
chr1_+_46668994 0.05 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr10_+_118350522 0.05 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr1_+_95699740 0.05 ENST00000429514.2
ENST00000263893.6
RWDD3
RWD domain containing 3
chr15_+_81589254 0.05 ENST00000394652.2
IL16
interleukin 16
chr7_-_73256838 0.05 ENST00000297873.4
WBSCR27
Williams Beuren syndrome chromosome region 27
chr11_-_46142505 0.04 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr21_+_46020497 0.04 ENST00000380102.2
KRTAP10-7
keratin associated protein 10-7
chr16_+_2255841 0.04 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr21_-_31864275 0.04 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr2_-_89399845 0.04 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr9_-_16870704 0.04 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr5_+_152870734 0.04 ENST00000521843.2
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr4_-_40632605 0.04 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr14_+_38677123 0.03 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr2_+_89184868 0.03 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr18_+_76829385 0.03 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr1_+_207039154 0.03 ENST00000367096.3
ENST00000391930.2
IL20
interleukin 20
chr10_-_101945771 0.03 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr7_-_4877677 0.03 ENST00000538469.1
RADIL
Ras association and DIL domains
chr2_-_208989225 0.03 ENST00000264376.4
CRYGD
crystallin, gamma D
chrX_-_153979315 0.03 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr4_-_47839966 0.03 ENST00000273857.4
ENST00000505909.1
ENST00000502252.1
CORIN
corin, serine peptidase
chr16_-_2379688 0.03 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr15_+_80351910 0.03 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr17_+_28804380 0.02 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr1_-_161087802 0.02 ENST00000368010.3
PFDN2
prefoldin subunit 2
chrX_+_46771711 0.02 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chrX_+_53078273 0.02 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr14_+_57735614 0.02 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr15_-_71407833 0.02 ENST00000449977.2
CT62
cancer/testis antigen 62
chr22_+_41956767 0.02 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr10_+_60094735 0.02 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr5_-_126409159 0.02 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr17_+_60704762 0.02 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr15_-_81202118 0.01 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chr22_+_21369316 0.01 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chrX_+_24711997 0.01 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr11_-_2193025 0.01 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
TH
tyrosine hydroxylase
chr19_+_54024251 0.01 ENST00000253144.9
ZNF331
zinc finger protein 331
chr11_-_40315640 0.01 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr11_+_75526212 0.01 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr17_-_67057203 0.01 ENST00000340001.4
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr3_+_49057876 0.01 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr16_-_4664860 0.01 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr1_-_89641680 0.01 ENST00000294671.2
GBP7
guanylate binding protein 7
chr6_+_28109703 0.00 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chrX_+_72064690 0.00 ENST00000438696.1
DMRTC1B
DMRT-like family C1B
chr6_-_168476511 0.00 ENST00000440994.2
FRMD1
FERM domain containing 1
chr10_+_50818343 0.00 ENST00000374115.3
SLC18A3
solute carrier family 18 (vesicular acetylcholine transporter), member 3
chr15_+_77712993 0.00 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr16_-_4665023 0.00 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr1_+_16370271 0.00 ENST00000375679.4
CLCNKB
chloride channel, voltage-sensitive Kb

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.5 GO:0061743 motor learning(GO:0061743)
0.1 1.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.9 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 0.7 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.8 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.8 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044301 climbing fiber(GO:0044301)
0.1 0.7 GO:0097443 sorting endosome(GO:0097443)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.5 GO:0032059 muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.4 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.2 GO:0031403 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse