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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZNF282

Z-value: 0.28

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ZNF282
ENSG00000170265.7 ZNF282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF282hg19_v2_chr7_+_148892557_1488925800.511.9e-01Click!

Activity profile of ZNF282 motif

Sorted Z-values of ZNF282 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_7942335 0.27 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
 ALOX15B
 arachidonate 15-lipoxygenase, type B
chr17_+_7942424 0.23 ENST00000573359.1
 ALOX15B
 arachidonate 15-lipoxygenase, type B
chr8_-_75233563 0.20 ENST00000342232.4
 JPH1
 junctophilin 1
chr20_-_62284766 0.18 ENST00000370053.1
 STMN3
 stathmin-like 3
chr1_+_2005425 0.18 ENST00000461106.2
 PRKCZ
 protein kinase C, zeta
chr1_+_2004901 0.17 ENST00000400921.2
 PRKCZ
 protein kinase C, zeta
chr1_+_13910757 0.12 ENST00000376061.4
ENST00000513143.1
 PDPN
 podoplanin
chr1_+_35247859 0.12 ENST00000373362.3
 GJB3
 gap junction protein, beta 3, 31kDa
chr5_+_167718604 0.12 ENST00000265293.4
 WWC1
 WW and C2 domain containing 1
chr1_+_13910479 0.12 ENST00000509009.1
 PDPN
 podoplanin
chr19_-_6110474 0.11 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
 RFX2
 regulatory factor X, 2 (influences HLA class II expression)
chr8_+_50822344 0.09 ENST00000518864.1
 SNTG1
 syntrophin, gamma 1
chr1_+_47799542 0.09 ENST00000471289.2
ENST00000450808.2
 CMPK1
 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr5_+_65892174 0.09 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr1_-_2126192 0.08 ENST00000378546.4
 C1orf86
 chromosome 1 open reading frame 86
chr17_-_77924627 0.08 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
 TBC1D16
 TBC1 domain family, member 16
chr10_+_11865347 0.08 ENST00000277570.5
 PROSER2
 proline and serine-rich protein 2
chr1_+_151171012 0.08 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
 PIP5K1A
 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr8_-_21988558 0.07 ENST00000312841.8
 HR
 hair growth associated
chr3_-_180707306 0.07 ENST00000479269.1
 DNAJC19
 DnaJ (Hsp40) homolog, subfamily C, member 19
chr20_+_62492566 0.07 ENST00000369916.3
 ABHD16B
 abhydrolase domain containing 16B
chr6_+_129204337 0.07 ENST00000421865.2
 LAMA2
 laminin, alpha 2
chr8_-_28347737 0.07 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
 FBXO16
 F-box protein 16
chr1_+_27320176 0.06 ENST00000522111.2
 TRNP1
 TMF1-regulated nuclear protein 1
chr1_+_52682052 0.06 ENST00000371591.1
 ZFYVE9
 zinc finger, FYVE domain containing 9
chr8_-_27630102 0.06 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
 CCDC25
 coiled-coil domain containing 25
chr16_+_67927147 0.06 ENST00000291041.5
 PSKH1
 protein serine kinase H1
chr20_-_44144249 0.06 ENST00000217428.6
 SPINT3
 serine peptidase inhibitor, Kunitz type, 3
chr14_-_36989336 0.05 ENST00000522719.2
 NKX2-1
 NK2 homeobox 1
chr1_+_45792541 0.05 ENST00000334815.3
 HPDL
 4-hydroxyphenylpyruvate dioxygenase-like
chr4_-_153457197 0.05 ENST00000281708.4
 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_-_24151892 0.05 ENST00000235958.4
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_-_24151903 0.05 ENST00000436439.2
ENST00000374490.3
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr21_+_35747773 0.05 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
 SMIM11
 small integral membrane protein 11
chr19_+_39390320 0.05 ENST00000576510.1
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr17_+_44039704 0.04 ENST00000420682.2
ENST00000415613.2
ENST00000571987.1
ENST00000574436.1
ENST00000431008.3
 MAPT
 microtubule-associated protein tau
chr6_+_139349817 0.04 ENST00000367660.3
 ABRACL
 ABRA C-terminal like
chr7_+_139026057 0.04 ENST00000541515.3
 LUC7L2
 LUC7-like 2 (S. cerevisiae)
chr2_+_233415488 0.04 ENST00000454501.1
 EIF4E2
 eukaryotic translation initiation factor 4E family member 2
chr17_+_8191815 0.04 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
 RANGRF
 RAN guanine nucleotide release factor
chr12_-_122296755 0.04 ENST00000289004.4
 HPD
 4-hydroxyphenylpyruvate dioxygenase
chr2_+_233897382 0.04 ENST00000233840.3
 NEU2
 sialidase 2 (cytosolic sialidase)
chr12_+_93964158 0.04 ENST00000549206.1
 SOCS2
 suppressor of cytokine signaling 2
chr3_-_180707466 0.04 ENST00000491873.1
ENST00000486355.1
ENST00000382564.2
 DNAJC19
 DnaJ (Hsp40) homolog, subfamily C, member 19
chr10_-_126480381 0.04 ENST00000368836.2
 METTL10
 methyltransferase like 10
chr11_-_321340 0.04 ENST00000526811.1
 IFITM3
 interferon induced transmembrane protein 3
chr11_-_6633799 0.04 ENST00000299424.4
 TAF10
 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr9_+_98534605 0.04 ENST00000600140.1
 DKFZP434H0512
 Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512
chr2_+_233415363 0.03 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
 EIF4E2
 eukaryotic translation initiation factor 4E family member 2
chr12_-_127256772 0.03 ENST00000536517.1
 LINC00944
 long intergenic non-protein coding RNA 944
chr13_+_31309645 0.03 ENST00000380490.3
 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
chr19_-_39390350 0.03 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2
 sirtuin 2
chr7_+_139025875 0.03 ENST00000297534.6
 C7orf55
 chromosome 7 open reading frame 55
chr5_-_175788758 0.03 ENST00000510164.1
ENST00000533553.1
ENST00000504688.1
ENST00000393725.2
ENST00000503082.1
ENST00000506983.1
 KIAA1191
 KIAA1191
chr19_+_39390587 0.03 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr5_+_175299743 0.03 ENST00000502265.1
 CPLX2
 complexin 2
chr19_-_40336969 0.03 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
 FBL
 fibrillarin
chr6_-_32151999 0.03 ENST00000375069.3
ENST00000538695.1
ENST00000438221.2
ENST00000375065.5
ENST00000450110.1
ENST00000375067.3
ENST00000375056.2
 AGER
 advanced glycosylation end product-specific receptor
chr19_-_39390440 0.03 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2
 sirtuin 2
chr1_-_2126174 0.03 ENST00000400919.3
ENST00000420515.1
ENST00000378543.2
ENST00000400918.3
 C1orf86
 chromosome 1 open reading frame 86
chr2_-_68479614 0.03 ENST00000234310.3
 PPP3R1
 protein phosphatase 3, regulatory subunit B, alpha
chr3_-_170588163 0.03 ENST00000295830.8
 RPL22L1
 ribosomal protein L22-like 1
chr19_+_44617511 0.03 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
 ZNF225
 zinc finger protein 225
chr11_+_63998006 0.03 ENST00000355040.4
 DNAJC4
 DnaJ (Hsp40) homolog, subfamily C, member 4
chrX_-_47004878 0.03 ENST00000377811.3
 NDUFB11
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr17_+_66509019 0.03 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_-_155947951 0.03 ENST00000313695.7
ENST00000497907.1
 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr6_-_32152064 0.03 ENST00000375076.4
ENST00000375070.3
 AGER
 advanced glycosylation end product-specific receptor
chr20_-_2451395 0.02 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
 SNRPB
 small nuclear ribonucleoprotein polypeptides B and B1
chr18_-_47018869 0.02 ENST00000583036.1
ENST00000580261.1
 RPL17
 ribosomal protein L17
chr1_+_47799446 0.02 ENST00000371873.5
 CMPK1
 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr6_-_32152020 0.02 ENST00000375055.2
 AGER
 advanced glycosylation end product-specific receptor
chr17_-_56605341 0.02 ENST00000583114.1
 SEPT4
 septin 4
chr18_-_47018897 0.02 ENST00000418495.1
 RPL17
 ribosomal protein L17
chr17_-_73937116 0.02 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
 FBF1
 Fas (TNFRSF6) binding factor 1
chr2_+_242289502 0.02 ENST00000451310.1
 SEPT2
 septin 2
chr3_-_170587974 0.02 ENST00000463836.1
 RPL22L1
 ribosomal protein L22-like 1
chr14_+_55590646 0.02 ENST00000553493.1
 LGALS3
 lectin, galactoside-binding, soluble, 3
chr18_-_47017956 0.02 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
 RPL17-C18orf32
RPL17
 RPL17-C18orf32 readthrough
ribosomal protein L17
chr18_-_47018769 0.02 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
 RPL17
 ribosomal protein L17
chr1_+_226250379 0.02 ENST00000366815.3
ENST00000366814.3
 H3F3A
 H3 histone, family 3A
chr11_-_111957451 0.02 ENST00000504148.2
ENST00000541231.1
 TIMM8B
 translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr17_-_61996136 0.02 ENST00000342364.4
 GH1
 growth hormone 1
chr19_-_49121054 0.02 ENST00000546623.1
ENST00000084795.5
 RPL18
 ribosomal protein L18
chr10_+_114135004 0.02 ENST00000393081.1
 ACSL5
 acyl-CoA synthetase long-chain family member 5
chr14_+_58711539 0.02 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
 PSMA3
 proteasome (prosome, macropain) subunit, alpha type, 3
chr17_-_73389854 0.02 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
 GRB2
 growth factor receptor-bound protein 2
chr12_+_57828521 0.02 ENST00000309668.2
 INHBC
 inhibin, beta C
chr4_+_39460659 0.01 ENST00000513731.1
 LIAS
 lipoic acid synthetase
chr4_+_169753156 0.01 ENST00000393726.3
ENST00000507735.1
 PALLD
 palladin, cytoskeletal associated protein
chr20_+_18269121 0.01 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
 ZNF133
 zinc finger protein 133
chr4_+_39460620 0.01 ENST00000340169.2
ENST00000261434.3
 LIAS
 lipoic acid synthetase
chr4_+_39460689 0.01 ENST00000381846.1
 LIAS
 lipoic acid synthetase
chr15_-_83736091 0.01 ENST00000261721.4
 BTBD1
 BTB (POZ) domain containing 1
chr5_+_7869217 0.01 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
 MTRR
 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr17_+_41323204 0.01 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
 NBR1
 neighbor of BRCA1 gene 1
chr12_+_122150646 0.01 ENST00000449592.2
 TMEM120B
 transmembrane protein 120B
chr2_-_241497390 0.01 ENST00000272972.3
ENST00000401804.1
ENST00000361678.4
ENST00000405523.3
 ANKMY1
 ankyrin repeat and MYND domain containing 1
chr12_+_54519842 0.01 ENST00000508564.1
 RP11-834C11.4
 RP11-834C11.4
chr13_+_50656307 0.01 ENST00000378180.4
 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
chr17_-_61988556 0.01 ENST00000309894.5
ENST00000438387.2
ENST00000346606.6
ENST00000561003.1
ENST00000450719.3
ENST00000259003.10
 CSHL1
 chorionic somatomammotropin hormone-like 1
chrX_-_49121165 0.01 ENST00000376207.4
ENST00000376199.2
 FOXP3
 forkhead box P3
chr12_-_127256858 0.01 ENST00000542248.1
ENST00000540684.1
 LINC00944
 long intergenic non-protein coding RNA 944
chr6_-_137314371 0.01 ENST00000432330.1
ENST00000418699.1
 RP11-55K22.5
 RP11-55K22.5
chr6_+_10748019 0.01 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
 SYCP2L
TMEM14B
 synaptonemal complex protein 2-like
transmembrane protein 14B
chr1_+_17248418 0.01 ENST00000375541.5
 CROCC
 ciliary rootlet coiled-coil, rootletin
chr11_+_111957497 0.01 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
 SDHD
 succinate dehydrogenase complex, subunit D, integral membrane protein
chr3_-_106959424 0.00 ENST00000607801.1
ENST00000479612.2
ENST00000484698.1
ENST00000477210.2
ENST00000473636.1
 LINC00882
 long intergenic non-protein coding RNA 882
chr4_+_52709229 0.00 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
 DCUN1D4
 DCN1, defective in cullin neddylation 1, domain containing 4
chr5_+_156887027 0.00 ENST00000435489.2
ENST00000311946.7
 NIPAL4
 NIPA-like domain containing 4
chr1_-_9129631 0.00 ENST00000377414.3
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_+_32938665 0.00 ENST00000374831.4
ENST00000395289.2
 BRD2
 bromodomain containing 2
chr17_+_42422637 0.00 ENST00000053867.3
ENST00000588143.1
 GRN
 granulin
chr13_-_95248511 0.00 ENST00000261296.5
 TGDS
 TDP-glucose 4,6-dehydratase
chrX_+_47004639 0.00 ENST00000345781.6
 RBM10
 RNA binding motif protein 10
chr17_+_42422662 0.00 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
 GRN
 granulin
chr12_+_4758264 0.00 ENST00000266544.5
 NDUFA9
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr16_+_29802036 0.00 ENST00000561482.1
ENST00000160827.4
ENST00000569636.2
ENST00000400750.2
 KIF22
 kinesin family member 22
chr9_+_126777676 0.00 ENST00000488674.2
 LHX2
 LIM homeobox 2
chr6_+_10747986 0.00 ENST00000379542.5
 TMEM14B
 transmembrane protein 14B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.5 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.0 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)