Project
Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Navigation
Downloads
Results for ZNF711_TFAP2A_TFAP2D
Z-value: 1.97
Motif logo
Transcription factors associated with ZNF711_TFAP2A_TFAP2D
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF711 | hg19_v2_chrX_+_84499081_84499115 | -0.89 | 2.8e-03 | Click! |
| TFAP2A | hg19_v2_chr6_-_10415470_10415508 | -0.70 | 5.1e-02 | Click! |
| TFAP2D | hg19_v2_chr6_+_50681541_50681541 | -0.46 | 2.5e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF711_TFAP2A_TFAP2D
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_47518011 | 2.10 |
ENST00000300527.4 ENST00000357838.4 ENST00000310645.5 |
COL6A2 |
collagen, type VI, alpha 2 |
| chr7_-_131241361 | 2.10 |
ENST00000378555.3 ENST00000322985.9 ENST00000541194.1 ENST00000537928.1 |
PODXL |
podocalyxin-like |
| chr2_-_225907150 | 2.09 |
ENST00000258390.7 |
DOCK10 |
dedicator of cytokinesis 10 |
| chr15_+_33010175 | 2.05 |
ENST00000300177.4 ENST00000560677.1 ENST00000560830.1 |
GREM1 |
gremlin 1, DAN family BMP antagonist |
| chr10_-_79397391 | 1.87 |
ENST00000286628.8 ENST00000406533.3 ENST00000354353.5 ENST00000404857.1 |
KCNMA1 |
potassium large conductance calcium-activated channel, subfamily M, alpha member 1 |
| chr10_-_100027943 | 1.75 |
ENST00000260702.3 |
LOXL4 |
lysyl oxidase-like 4 |
| chr22_+_45898712 | 1.71 |
ENST00000455233.1 ENST00000348697.2 ENST00000402984.3 ENST00000262722.7 ENST00000327858.6 ENST00000442170.2 ENST00000340923.5 ENST00000439835.1 |
FBLN1 |
fibulin 1 |
| chr15_-_48937982 | 1.65 |
ENST00000316623.5 |
FBN1 |
fibrillin 1 |
| chr10_+_31608054 | 1.59 |
ENST00000320985.10 ENST00000361642.5 ENST00000560721.2 ENST00000558440.1 ENST00000424869.1 ENST00000542815.3 |
ZEB1 |
zinc finger E-box binding homeobox 1 |
| chr2_+_33172221 | 1.59 |
ENST00000354476.3 |
LTBP1 |
latent transforming growth factor beta binding protein 1 |
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 9.6 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.6 | 6.3 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 4.9 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724) |
| 0.2 | 4.2 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.1 | 3.9 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 3.9 | GO:1902749 | regulation of cell cycle G2/M phase transition(GO:1902749) |
| 1.2 | 3.6 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.1 | 3.3 | GO:0032392 | DNA geometric change(GO:0032392) |
| 0.2 | 3.2 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.2 | 3.2 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.3 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 12.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 7.5 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 7.3 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 6.8 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 6.7 | GO:0044309 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
| 0.3 | 6.4 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 6.4 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 6.0 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 5.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 9.2 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.1 | 6.2 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 5.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 4.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 4.4 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.1 | 4.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 4.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 4.1 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.4 | 3.8 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.3 | 3.8 | GO:0004955 | prostaglandin receptor activity(GO:0004955) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 8.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 6.4 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 6.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 5.8 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 5.7 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.1 | 5.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 5.1 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 4.9 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 4.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.1 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 10.0 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 6.9 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 5.8 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 5.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 4.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 4.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 4.1 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 3.7 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |
| 0.1 | 3.5 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |