Motif ID: CDC5L.p2

Z-value: 1.734


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_44463265-0.233.9e-01Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_59705918 3.710 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr18_+_59593591 3.350 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr13_-_37070862 2.859 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr9_+_74956614 2.824 ANXA1
annexin A1
chr9_+_74956494 2.662 NM_000700
ANXA1
annexin A1
chr9_+_74956601 2.530 ANXA1
annexin A1
chr1_+_151270301 1.939 NM_003125
SPRR1B
small proline-rich protein 1B
chr17_-_7434113 1.882 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr4_-_15549047 1.769 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr3_+_123526700 1.561 NM_005213
CSTA
cystatin A (stefin A)
chr8_-_102029997 1.465 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_-_20682541 1.413


chr20_-_1420168 1.355 NM_001122962
NM_001134836
SIRPB2

signal-regulatory protein beta 2

chr6_-_49712483 1.324 NM_000324
RHAG
Rh-associated glycoprotein
chr5_+_147423727 1.229 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr2_-_162808123 1.216 NM_004460
FAP
fibroblast activation protein, alpha
chr9_-_109291866 1.174 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr14_-_60818263 1.129 NM_001017970
TMEM30B
transmembrane protein 30B
chr6_-_136888771 1.123 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr2_-_160764819 1.065 NM_000888
ITGB6
integrin, beta 6
chr6_-_112001590 0.995 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr8_+_32623792 0.971 NM_013959
NRG1
neuregulin 1
chrX_+_110252960 0.903 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr1_-_180624380 0.888 GLUL
glutamate-ammonia ligase
chr12_+_13240987 0.878 EMP1
epithelial membrane protein 1
chr9_+_124173143 0.860 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_136889302 0.860 MAP7
microtubule-associated protein 7
chr3_-_152517204 0.829 NM_023915
GPR87
G protein-coupled receptor 87
chr7_+_18502342 0.822 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr2_-_160765008 0.811 ITGB6
integrin, beta 6
chr12_+_21417068 0.796 NM_000415
IAPP
islet amyloid polypeptide
chr15_+_30721161 0.775 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr8_-_110762409 0.774 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr10_-_105835609 0.764 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr12_-_51114372 0.733 NM_004693
KRT75
keratin 75
chr8_-_49996353 0.732 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr7_+_80105907 0.728 CD36
CD36 molecule (thrombospondin receptor)
chr10_-_21226536 0.726 NM_006393
NEBL
nebulette
chr11_+_101488380 0.724 NM_001195045
YAP1
Yes-associated protein 1
chr7_+_80105858 0.707 CD36
CD36 molecule (thrombospondin receptor)
chr12_+_28301399 0.671 NM_018318
CCDC91
coiled-coil domain containing 91
chr21_+_38550533 0.664 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr19_-_10558906 0.652 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr7_-_122627235 0.648 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr11_-_124831391 0.647 FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr1_-_180624494 0.641 GLUL
glutamate-ammonia ligase
chr9_-_94338072 0.630 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr9_+_124172644 0.616 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_73973640 0.611 ACTG2
actin, gamma 2, smooth muscle, enteric
chr15_-_53349775 0.611 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr10_-_61819493 0.610 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_+_18501876 0.581 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr2_+_234255322 0.577 NM_019077
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chrX_+_135058402 0.556 NM_001159700
FHL1
four and a half LIM domains 1
chr5_+_140719773 0.554 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr10_-_27097782 0.544 ABI1
abl-interactor 1
chr2_+_73973600 0.536 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr7_+_77307382 0.524 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr2_+_211166323 0.520 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr9_+_134843918 0.519 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr12_-_44919818 0.517 SLC38A1
solute carrier family 38, member 1
chr3_-_9266251 0.509 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr11_+_59580705 0.502 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr1_+_194887630 0.494 NM_000186
NM_001014975
CFH

complement factor H

chrX_+_105823723 0.491 NM_024539
RNF128
ring finger protein 128
chr1_+_151223180 0.482 NM_005987
SPRR1A
small proline-rich protein 1A
chr9_+_124173049 0.477 NM_000962
NM_080591
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr4_+_38740246 0.469 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr11_+_59580630 0.468 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr16_+_1668291 0.467 HN1L
hematological and neurological expressed 1-like
chr6_+_121798443 0.466 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr9_-_109291130 0.456 KLF4
Kruppel-like factor 4 (gut)
chr9_+_109131814 0.446 RAD23B
RAD23 homolog B (S. cerevisiae)
chr21_+_39117064 0.444 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr1_-_93030538 0.441 NM_005665
EVI5
ecotropic viral integration site 5
chr4_+_53986759 0.435 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr2_+_183316574 0.434 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr5_+_140146059 0.429 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr2_+_101981888 0.424 NM_173343
IL1R2
interleukin 1 receptor, type II
chr10_+_91142301 0.416 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr2_+_204279624 0.414 CD28
CD28 molecule
chr8_+_39890484 0.397 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr2_+_101874809 0.395 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr15_+_47502666 0.393 NM_002009
FGF7
fibroblast growth factor 7
chr3_-_124822113 0.381 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr22_-_34566367 0.379 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr2_+_101874765 0.378 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_215949566 0.376 FN1
fibronectin 1
chr2_+_204279442 0.362 NM_006139
CD28
CD28 molecule
chr8_-_86441115 0.360 NM_001164830
CA1
carbonic anhydrase I
chr12_-_44877769 0.355 SLC38A1
solute carrier family 38, member 1
chr12_+_77963563 0.354 NM_001135806
SYT1
synaptotagmin I
chrX_+_99726445 0.353 NM_022144
TNMD
tenomodulin
chr11_-_13474101 0.340 NM_000315
PTH
parathyroid hormone
chr1_-_25619863 0.338 NM_020485
NM_138616
NM_138617
NM_138618
RHCE



RHD
Rh blood group, CcEe antigens



Rh blood group, D antigen
chrX_-_106336199 0.338 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr6_-_155818728 0.335 NM_015718
NOX3
NADPH oxidase 3
chr1_+_25471470 0.333 NM_001127691
NM_016124
RHD

Rh blood group, D antigen

chr3_+_190831909 0.333 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr2_+_165804157 0.332 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr11_-_113971607 0.330 FAM55D
family with sequence similarity 55, member D
chr5_-_137876416 0.329 ETF1
eukaryotic translation termination factor 1
chr21_-_35343456 0.327 NM_001754
RUNX1
runt-related transcription factor 1
chr7_-_16471817 0.320 NM_015464
SOSTDC1
sclerostin domain containing 1
chr9_-_111230926 0.319 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr10_-_121286034 0.318 NM_002925
RGS10
regulator of G-protein signaling 10
chr16_+_1668257 0.317 NM_144570
HN1L
hematological and neurological expressed 1-like
chr16_+_1668284 0.316 HN1L
hematological and neurological expressed 1-like
chr12_-_89922888 0.308 NM_004950
EPYC
epiphycan
chrX_+_30171768 0.308 NM_002363
NM_177415
MAGEB1

melanoma antigen family B, 1

chr12_-_52975823 0.308 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr11_-_117640166 0.308 MPZL2
myelin protein zero-like 2
chr18_-_49944986 0.305 MBD2
methyl-CpG binding domain protein 2
chr3_-_171070314 0.305 NM_024727
LRRC31
leucine rich repeat containing 31
chr4_+_70831387 0.299 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chrX_-_110541029 0.299 NM_000555
DCX
doublecortin
chrX_+_65300803 0.296 NM_001130860
NM_014799
HEPH

hephaestin

chr5_+_96237923 0.296 ERAP2
endoplasmic reticulum aminopeptidase 2
chr2_+_151922350 0.294 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr10_-_62163083 0.288 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_148726497 0.283 TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr7_-_13992351 0.281 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr2_-_225078931 0.279 CUL3
cullin 3
chr10_-_69095362 0.274 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr9_-_94206648 0.274 NM_014057
NM_033014
OGN

osteoglycin

chr6_+_4835224 0.273 NM_001143971
CDYL
chromodomain protein, Y-like
chr1_+_234624266 0.273 NM_145861
EDARADD
EDAR-associated death domain
chr10_-_69422391 0.272 HERC4
hect domain and RLD 4
chr12_-_90100679 0.269 DCN
decorin
chr3_+_137224266 0.268 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr20_-_39362122 0.264 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr5_+_128468785 0.264 ISOC1
isochorismatase domain containing 1
chr7_+_80105718 0.260 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr16_+_33168191 0.257 NM_001099687
TP53TG3B
TP53 target 3B
chr16_+_33111656 0.256 NM_001099687
TP53TG3B
TP53 target 3B
chr2_+_43854681 0.253 NM_001193464
NM_015522
NM_016008
DYNC2LI1


dynein, cytoplasmic 2, light intermediate chain 1


chr1_+_24713396 0.249 RCAN3
RCAN family member 3
chr11_-_130291584 0.247 NM_014758
SNX19
sorting nexin 19
chrX_+_123062143 0.246 STAG2
stromal antigen 2
chr2_+_66516196 0.245 MEIS1
Meis homeobox 1
chr15_+_39853982 0.241 MAPKBP1
mitogen-activated protein kinase binding protein 1
chr8_+_104380234 0.240 NM_001164616
NM_003506
FZD6

frizzled homolog 6 (Drosophila)

chr5_+_156540425 0.239 NM_005546
ITK
IL2-inducible T-cell kinase
chrX_+_77889861 0.238 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr12_-_52975777 0.237 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr12_-_90097384 0.233 NM_133503
DCN
decorin
chr3_-_124821868 0.229 MYLK
myosin light chain kinase
chr21_-_35343500 0.224 RUNX1
runt-related transcription factor 1
chr12_+_108452117 0.222 UBE3B
ubiquitin protein ligase E3B
chr4_-_123596921 0.222 NM_000586
IL2
interleukin 2
chr6_+_132000134 0.222 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_+_119174947 0.218 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr18_+_59405513 0.216 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr2_-_183095308 0.215 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr8_-_62764839 0.214 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr1_+_86707113 0.212 NM_001285
CLCA1
chloride channel accessory 1
chr13_-_43908937 0.211 TSC22D1
TSC22 domain family, member 1
chr11_-_84311867 0.211 DLG2
discs, large homolog 2 (Drosophila)
chr14_+_69307914 0.209 SRSF5
serine/arginine-rich splicing factor 5
chr17_-_2913650 0.207 NM_014566
OR1D4
OR1D5
olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
olfactory receptor, family 1, subfamily D, member 5
chr19_-_21438525 0.204


chr12_-_90100710 0.203 DCN
decorin
chr6_-_90081655 0.203 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr11_-_84312085 0.202 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr7_+_110518297 0.199 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chrX_-_107569256 0.199 NM_001847
COL4A6
collagen, type IV, alpha 6
chr6_+_28032997 0.197 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr21_+_38550739 0.197 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_21818881 0.196 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr3_+_114948591 0.195 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr19_+_12995782 0.194 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_+_210152609 0.192 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr21_-_35343448 0.191 RUNX1
runt-related transcription factor 1
chrX_-_23835868 0.191 NM_024122
APOO
apolipoprotein O
chr4_-_87500398 0.190 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr4_+_53975597 0.190 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr4_-_145159889 0.188 NM_002100
GYPB
glycophorin B (MNS blood group)
chr1_+_50344550 0.187 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_+_140200995 0.187 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr4_-_77176163 0.186 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr5_+_161210280 0.186 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr12_-_66905802 0.185 NM_018402
IL26
interleukin 26
chr10_+_102113410 0.185


chr10_+_106003941 0.185 NM_001191003
GSTO1
glutathione S-transferase omega 1
chr12_+_18305740 0.184 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr10_-_62002672 0.184 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_215605054 0.181 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_+_115373937 0.181 NM_000549
TSHB
thyroid stimulating hormone, beta
chr8_+_104900591 0.179 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr12_-_85756766 0.178 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chrX_+_115215985 0.178 NM_000686
AGTR2
angiotensin II receptor, type 2
chr12_-_90100733 0.177 NM_001920
DCN
decorin
chr20_-_1922393 0.177 NM_001190900
PDYN
prodynorphin
chr15_+_39853923 0.177 NM_001128608
NM_014994
MAPKBP1

mitogen-activated protein kinase binding protein 1

chrX_+_102918409 0.176 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr17_-_64462976 0.174 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr1_+_100099353 0.173 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr2_+_172530120 0.173 HAT1
histone acetyltransferase 1
chr3_+_191588354 0.172 NM_006580
CLDN16
claudin 16
chr4_-_87247829 0.171 NM_138981
MAPK10
mitogen-activated protein kinase 10

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
9.66 2.10e-04 GO:0018149 peptide cross-linking
1.34 3.31e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.71 4.58e-06 GO:0005576 extracellular region
1.37 4.56e-04 GO:0071944 cell periphery
1.79 8.40e-04 GO:0044421 extracellular region part
2.60 1.31e-03 GO:0005578 proteinaceous extracellular matrix
1.34 2.75e-03 GO:0005886 plasma membrane
1.54 3.63e-02 GO:0005887 integral to plasma membrane
2.15 3.96e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.87 3.09e-02 GO:0005509 calcium ion binding
13.49 4.54e-02 GO:0005132 interferon-alpha/beta receptor binding