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• Activity deltas table
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Motif ID: ETS1,2.p2

Z-value: 2.144

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_31003260	2.770	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr1_-_31003181	2.575		LAPTM5	lysosomal protein transmembrane 5
chr2_-_109728958	2.118	NM_144710 NM_178584	SEPT10	septin 10
chr19_+_54530546	2.050		CD37	CD37 molecule
chr2_+_33514896	1.890	NM_170672	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_-_47604930	1.838	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr12_-_6103945	1.803	NM_000552	VWF	von Willebrand factor
chr9_+_115396020	1.756	NM_144489	RGS3	regulator of G-protein signaling 3
chr19_+_54530512	1.679		CD37	CD37 molecule
chr10_-_98021144	1.676	NM_001114094 NM_013314	BLNK	B-cell linker
chr19_+_54530497	1.632		CD37	CD37 molecule
chr19_+_54530485	1.631	NM_001040031 NM_001774	CD37	CD37 molecule
chr2_-_109728693	1.625		SEPT10	septin 10
chr21_-_45165249	1.519		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_11490487	1.496	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr19_+_54530458	1.482		CD37	CD37 molecule
chr21_-_45165302	1.479	NM_000211	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_149772469	1.442	NM_001025159 NM_004355 NM_001025158	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr14_-_106184988	1.414		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_149960612	1.377	NM_024711	GIMAP6	GTPase, IMAP family member 6
chr7_-_149960218	1.359		GIMAP6	GTPase, IMAP family member 6
chr5_-_149772563	1.354		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr10_-_88707299	1.320	NM_024756	MMRN2	multimerin 2
chr14_+_20319049	1.296	NM_005615	RNASE6	ribonuclease, RNase A family, k6
chr16_+_30102426	1.281		CORO1A	coronin, actin binding protein, 1A
chr2_-_96174865	1.240	NM_004418	DUSP2	dual specificity phosphatase 2
chr12_+_6925997	1.238	NM_080548	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr12_+_6926014	1.223		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr8_+_75066117	1.217	NM_001195797 NM_015364	LY96	lymphocyte antigen 96
chr1_-_181826086	1.192		NCF2	neutrophil cytosolic factor 2
chr22_-_35875890	1.186	NM_000878	IL2RB	interleukin 2 receptor, beta
chr10_+_129595289	1.162	NM_006504	PTPRE	protein tyrosine phosphatase, receptor type, E
chr21_-_45165204	1.159		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_+_5667494	1.129	NM_006074	TRIM22	tripartite motif containing 22
chr20_+_43874735	1.078		UBE2C	ubiquitin-conjugating enzyme E2C
chr2_+_118562499	1.076	NM_016133	INSIG2	insulin induced gene 2
chrX_+_114734074	1.073	NM_001136025 NM_001172335	PLS3	plastin 3
chr9_-_88159143	1.050	NM_001185059 NM_001185074 NM_024617	ZCCHC6	zinc finger, CCHC domain containing 6
chr14_+_105024576	1.042		CRIP1	cysteine-rich protein 1 (intestinal)
chr14_-_22354457	1.020		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr11_+_7574992	1.010		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_+_102320148	0.998	NM_003856	IL1RL1	interleukin 1 receptor-like 1
chr4_+_8251818	0.968	NM_018986	SH3TC1	SH3 domain and tetratricopeptide repeats 1
chr11_+_59979857	0.940	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr14_-_93926679	0.934	NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr5_+_156625629	0.918	NM_001037333 NM_001037332	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr20_+_43874654	0.916	NM_007019 NM_181799 NM_181800 NM_181802 NM_181803	UBE2C	ubiquitin-conjugating enzyme E2C
chr7_+_149895390	0.916	NM_018326	GIMAP4	GTPase, IMAP family member 4
chr1_-_181826292	0.902	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr12_+_27288344	0.884	NM_015000	STK38L	serine/threonine kinase 38 like
chr12_+_51979721	0.883	NM_021640	C12orf10	chromosome 12 open reading frame 10
chr13_+_110604039	0.883	NM_003899	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr5_-_94443300	0.872	NM_001002796	MCTP1	multiple C2 domains, transmembrane 1
chr17_+_18320822	0.870	NM_001040078	LGALS9B LGALS9C	lectin, galactoside-binding, soluble, 9B lectin, galactoside-binding, soluble, 9C
chr17_-_35975227	0.866	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chrY_+_2769596	0.864	NM_001008	RPS4Y1	ribosomal protein S4, Y-linked 1
chrY_+_2769630	0.861		RPS4Y1	ribosomal protein S4, Y-linked 1
chr1_+_43539239	0.856	NM_005424	TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_-_90178630	0.842		RRAGD	Ras-related GTP binding D
chr16_+_30391460	0.839	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr7_+_150065376	0.838	NM_018384	GIMAP5	GTPase, IMAP family member 5
chr6_+_110119190	0.831		FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr20_+_43875078	0.815	NM_181801	UBE2C	ubiquitin-conjugating enzyme E2C
chr22_+_35586950	0.809	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr4_-_84254873	0.796		PLAC8	placenta-specific 8
chr10_-_91092410	0.796		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr16_+_80370426	0.796	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr14_-_23106372	0.794		AP1G2	adaptor-related protein complex 1, gamma 2 subunit
chr3_-_11660395	0.794	NM_001128219	VGLL4	vestigial like 4 (Drosophila)
chr1_+_6008956	0.791	NM_003636 NM_172130	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr8_+_82355322	0.791	NM_001444	FABP5	fatty acid binding protein 5 (psoriasis-associated)
chr4_-_84254912	0.790		PLAC8	placenta-specific 8
chr20_-_23014828	0.782	NM_012072	CD93	CD93 molecule
chr15_+_79376295	0.782	NM_004513	IL16	interleukin 16 (lymphocyte chemoattractant factor)
chr6_+_110119116	0.777	NM_014845	FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr6_-_112186977	0.770	NM_153048	FYN	FYN oncogene related to SRC, FGR, YES
chr9_-_21325239	0.753	NM_018847	KLHL9	kelch-like 9 (Drosophila)
chr16_+_64958025	0.749	NM_001795	CDH5	cadherin 5, type 2 (vascular endothelium)
chr6_+_110119214	0.748		FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr22_-_16060485	0.747	NM_177405	CECR1	cat eye syndrome chromosome region, candidate 1
chr17_+_22982319	0.741		LGALS9	lectin, galactoside-binding, soluble, 9
chr20_+_44180296	0.741	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr1_-_158883666	0.729	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr14_-_105762742	0.728
chr12_+_6472782	0.726		NCAPD2	non-SMC condensin I complex, subunit D2
chr12_-_6668787	0.720	NM_001039918 NM_133476	ZNF384	zinc finger protein 384
chr22_-_36212160	0.716	NM_001166343 NM_002405	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_+_47073029	0.711	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr17_+_22982344	0.710		LGALS9	lectin, galactoside-binding, soluble, 9
chr12_+_6930799	0.710		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr15_+_72861470	0.708	NM_001127190 NM_004383	CSK	c-src tyrosine kinase
chr1_+_185064654	0.706	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr2_+_109729176	0.699	NM_023016	ANKRD57	ankyrin repeat domain 57
chr9_+_76893232	0.698		OSTF1	osteoclast stimulating factor 1
chr12_-_47605478	0.696	NM_001143782 NM_016594	FKBP11	FK506 binding protein 11, 19 kDa
chr22_-_35970133	0.694		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr10_+_114125955	0.694		ACSL5	acyl-CoA synthetase long-chain family member 5
chr8_-_29262240	0.693	NM_057158	DUSP4	dual specificity phosphatase 4
chr12_+_6930778	0.691		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr22_-_35970230	0.685	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr14_-_22354851	0.684	NM_001126105 NM_003982	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr12_+_6930815	0.682		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr7_+_73262283	0.680		LAT2	linker for activation of T cells family, member 2
chr7_+_150065594	0.677		GIMAP5	GTPase, IMAP family member 5
chr12_+_6930694	0.666	NM_002831 NM_080549	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr19_-_19615452	0.663	NM_016573	GMIP	GEM interacting protein
chr3_-_126325132	0.654		SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chrX_+_128741562	0.648	NM_018990	SASH3	SAM and SH3 domain containing 3
chr7_+_73262022	0.645	NM_014146 NM_032463 NM_032464	LAT2	linker for activation of T cells family, member 2
chr16_+_30391550	0.645		ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr9_-_122716670	0.644	NM_001190947	TRAF1	TNF receptor-associated factor 1
chr3_-_122862447	0.643	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr12_+_6930792	0.643		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_+_32489426	0.643	NM_005356	LCK	lymphocyte-specific protein tyrosine kinase
chr6_-_29635456	0.638		UBD	ubiquitin D
chr14_+_23771942	0.638	NM_001002002 NM_016576	GMPR2	guanosine monophosphate reductase 2
chr17_+_4784097	0.637		RNF167	ring finger protein 167
chr17_-_20311411	0.637	NM_001042685	LGALS9B	lectin, galactoside-binding, soluble, 9B
chrX_+_128741578	0.635		SASH3	SAM and SH3 domain containing 3
chr12_+_6930804	0.631		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr10_+_26767657	0.630		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_+_114126004	0.629		ACSL5	acyl-CoA synthetase long-chain family member 5
chr12_-_91063441	0.627	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative
chr6_-_90178685	0.626	NM_021244	RRAGD	Ras-related GTP binding D
chr3_-_173010921	0.625	NM_001130081 NM_002662	PLD1	phospholipase D1, phosphatidylcholine-specific
chr15_-_68971665	0.621	NM_020147	THAP10	THAP domain containing 10
chr12_-_109372489	0.620		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr14_+_105024301	0.617	NM_001311	CRIP1	cysteine-rich protein 1 (intestinal)
chr10_+_26767698	0.617		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr3_-_122862391	0.609		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr4_+_2783764	0.609		SH3BP2	SH3-domain binding protein 2
chr17_+_4784524	0.602		RNF167	ring finger protein 167
chr1_+_32512298	0.600	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase
chr14_+_75687997	0.599	NM_017926 NM_017972	C14orf118	chromosome 14 open reading frame 118
chr1_-_27825178	0.594	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr17_+_4784330	0.590	NM_015528	RNF167	ring finger protein 167
chr21_+_17807167	0.589	NM_001338	CXADR	coxsackie virus and adenovirus receptor
chr6_-_90178544	0.589		RRAGD	Ras-related GTP binding D
chr7_+_73262264	0.587		LAT2	linker for activation of T cells family, member 2
chr14_+_75688042	0.583		C14orf118	chromosome 14 open reading frame 118
chr8_-_101391356	0.582		RNF19A	ring finger protein 19A
chr22_+_21053972	0.579
chr7_-_5535726	0.578		ACTB	actin, beta
chr12_-_109372481	0.575		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr17_+_22982372	0.575		LGALS9	lectin, galactoside-binding, soluble, 9
chr6_-_32892705	0.573	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr12_-_109372535	0.563	NM_005719	ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr2_-_175170674	0.563		WIPF1	WAS/WASL interacting protein family, member 1
chr16_+_80370400	0.561		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr20_+_44180355	0.557		CD40	CD40 molecule, TNF receptor superfamily member 5
chr11_-_88864061	0.557	NM_001143836 NM_016931	NOX4	NADPH oxidase 4
chr18_+_13208777	0.556	NM_181481 NM_181482	C18orf1	chromosome 18 open reading frame 1
chr12_-_6668880	0.556	NM_001039917 NM_001039919 NM_001039920 NM_001135734	ZNF384	zinc finger protein 384
chr2_+_30223304	0.553		YPEL5	yippee-like 5 (Drosophila)
chr2_+_30223372	0.553		YPEL5	yippee-like 5 (Drosophila)
chr5_-_151046638	0.553		SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr5_+_134012133	0.553	NM_021982	SEC24A	SEC24 family, member A (S. cerevisiae)
chrX_-_106905657	0.552	NM_198057	TSC22D3	TSC22 domain family, member 3
chr6_-_32605898	0.552	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr4_+_68107039	0.548	NM_012108	STAP1	signal transducing adaptor family member 1
chr1_+_181380837	0.547		LAMC1	laminin, gamma 1 (formerly LAMB2)
chr2_+_30223253	0.546	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr8_+_56954899	0.540	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr9_-_129656581	0.535		ENG	endoglin
chr9_+_127549437	0.534	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr17_-_959007	0.532	NM_001092	ABR	active BCR-related gene
chr7_-_120285245	0.532		TSPAN12	tetraspanin 12
chr9_-_122728173	0.529		TRAF1	TNF receptor-associated factor 1
chr17_+_22982278	0.528	NM_002308 NM_009587	LGALS9	lectin, galactoside-binding, soluble, 9
chr3_+_48482213	0.527	NM_016381 NM_033629	TREX1	three prime repair exonuclease 1
chr9_-_129656830	0.527	NM_000118 NM_001114753	ENG	endoglin
chr17_+_29606408	0.526	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr2_+_218790109	0.526	NM_152862	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr8_+_56954946	0.525		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr10_+_129735796	0.525	NM_130435	PTPRE	protein tyrosine phosphatase, receptor type, E
chr2_-_69724209	0.525		AAK1	AP2 associated kinase 1
chr6_-_133126278	0.522	NM_078488	VNN2	vanin 2
chr9_+_115382760	0.520	NM_021106	RGS3	regulator of G-protein signaling 3
chr12_-_51887318	0.517		ITGB7	integrin, beta 7
chr9_-_129656778	0.516		ENG	endoglin
chr15_-_78050515	0.515	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr14_-_76993641	0.514	NM_001193314 NM_001193315 NM_001193316 NM_001193317 NM_022067	VIPAR	VPS33B interacting protein, apical-basolateral polarity regulator
chr9_-_129656413	0.513		ENG	endoglin
chr19_-_19615369	0.511		GMIP	GEM interacting protein
chr1_-_24067347	0.511	NM_000147	FUCA1	fucosidase, alpha-L- 1, tissue
chr5_-_171547700	0.508		STK10	serine/threonine kinase 10
chr19_-_43800374	0.508	NM_001042600 NM_007181	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr6_-_32665409	0.508	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr11_-_66961709	0.505	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr3_+_120799411	0.505	NM_015900	PLA1A	phospholipase A1 member A
chr1_-_205161821	0.503	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr2_+_71148915	0.501	NM_017567	NAGK	N-acetylglucosamine kinase
chr12_+_64504408	0.501	NM_003483 NM_003484	HMGA2	high mobility group AT-hook 2
chr12_-_109372462	0.499		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr9_-_76892860	0.499	NM_001127603 NM_017881	C9orf95	chromosome 9 open reading frame 95
chr2_+_218790143	0.498		ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr8_+_38763878	0.496	NM_001122824 NM_006283	TACC1	transforming, acidic coiled-coil containing protein 1
chr14_-_105644300	0.494		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr3_-_11736946	0.491	NM_014667	VGLL4	vestigial like 4 (Drosophila)
chr2_+_230798687	0.491	NM_001005176 NM_007237	SP140	SP140 nuclear body protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.36	2.95e-07	GO:0048583	regulation of response to stimulus
1.71	7.32e-07	GO:0001775	cell activation
1.40	1.35e-05	GO:0002376	immune system process
1.37	6.90e-05	GO:0009966	regulation of signal transduction
1.78	7.95e-05	GO:0051056	regulation of small GTPase mediated signal transduction
1.59	1.49e-03	GO:0002684	positive regulation of immune system process
1.19	1.95e-03	GO:0007165	signal transduction
1.84	1.95e-03	GO:0051249	regulation of lymphocyte activation
1.42	2.47e-03	GO:0048584	positive regulation of response to stimulus
1.78	3.02e-03	GO:0002694	regulation of leukocyte activation
1.76	3.33e-03	GO:0050865	regulation of cell activation
1.43	3.34e-03	GO:0006955	immune response
2.25	3.46e-03	GO:0035023	regulation of Rho protein signal transduction
2.23	4.72e-03	GO:0050851	antigen receptor-mediated signaling pathway
1.76	5.50e-03	GO:0045321	leukocyte activation
1.28	6.42e-03	GO:0023051	regulation of signaling
1.43	9.32e-03	GO:0002682	regulation of immune system process
1.91	1.14e-02	GO:0050900	leukocyte migration
1.73	1.48e-02	GO:0030168	platelet activation
1.11	2.34e-02	GO:0050794	regulation of cellular process
1.75	2.69e-02	GO:0046578	regulation of Ras protein signal transduction
1.16	3.28e-02	GO:0023052	signaling
2.04	3.53e-02	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.55	3.63e-02	GO:0044419	interspecies interaction between organisms
1.47	3.73e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.82	3.90e-02	GO:0051251	positive regulation of lymphocyte activation
1.78	4.23e-02	GO:0002764	immune response-regulating signaling pathway
2.05	4.44e-02	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.92	4.65e-02	GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade
1.24	4.94e-02	GO:0006464	protein modification process
1.48	4.94e-02	GO:0009967	positive regulation of signal transduction

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.53	7.39e-03	GO:0030695	GTPase regulator activity
1.50	1.42e-02	GO:0060589	nucleoside-triphosphatase regulator activity