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Motif ID: EVI1.p2

Z-value: 0.649

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_50699965	1.712		HLF	hepatic leukemia factor
chr4_+_74493918	1.333		ALB	albumin
chr10_+_7785347	1.302		ITIH2	inter-alpha (globulin) inhibitor H2
chr10_+_7785331	1.298		ITIH2	inter-alpha (globulin) inhibitor H2
chr4_+_74500748	1.218		ALB	albumin
chr4_+_74520796	1.191	NM_001134	AFP	alpha-fetoprotein
chr10_+_7785360	1.061		ITIH2	inter-alpha (globulin) inhibitor H2
chr14_+_94117545	0.988		SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr14_+_94117511	0.975		SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr10_+_7785290	0.938		ITIH2	inter-alpha (globulin) inhibitor H2
chr1_-_159459814	0.877		APOA2	apolipoprotein A-II
chr4_+_74491272	0.808		ALB	albumin
chr8_-_17812151	0.793
chr10_+_7785235	0.715	NM_002216	ITIH2	inter-alpha (globulin) inhibitor H2
chr11_+_22652894	0.708	NM_005256	GAS2	growth arrest-specific 2
chr3_+_187813405	0.646		AHSG	alpha-2-HS-glycoprotein
chr4_+_74496575	0.640		ALB	albumin
chr1_+_50342168	0.632	NM_001144776	ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_159459999	0.628	NM_001643	APOA2	apolipoprotein A-II
chr1_-_145163779	0.577	NM_001144829 NM_001144830 NM_001461	FMO5	flavin containing monooxygenase 5
chr1_-_145163520	0.572		FMO5	flavin containing monooxygenase 5
chr11_+_60765219	0.569	NM_014224	PGA5	pepsinogen 5, group I (pepsinogen A)
chr5_+_139856688	0.557		ANKHD1	ankyrin repeat and KH domain containing 1
chrX_+_115481774	0.539	NM_007231	SLC6A14	solute carrier family 6 (amino acid transporter), member 14
chr4_+_155703581	0.537	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr17_-_59437782	0.535	NM_000873	ICAM2	intercellular adhesion molecule 2
chr4_+_74496660	0.530		ALB	albumin
chr11_+_60746396	0.501	NM_001079808	PGA5 PGA3 PGA4	pepsinogen 5, group I (pepsinogen A) pepsinogen 3, group I (pepsinogen A) pepsinogen 4, group I (pepsinogen A)
chr20_-_45418818	0.496	NM_012408 NM_183047 NM_183048	ZMYND8	zinc finger, MYND-type containing 8
chr11_+_22646229	0.489	NM_177553	GAS2	growth arrest-specific 2
chr14_+_94117483	0.470	NM_000624	SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr11_-_33847937	0.450	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr11_-_33848061	0.446	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr4_-_23500706	0.445	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_33848013	0.438		LMO2	LIM domain only 2 (rhombotin-like 1)
chr6_+_32003180	0.381	NM_000063 NM_001145903	C2	complement component 2
chrX_-_74292800	0.376	NM_004299	ABCB7	ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr7_-_87180499	0.367	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr17_-_53849888	0.367		RNF43	ring finger protein 43
chr14_-_93914634	0.365		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_+_71096830	0.362	NM_017855	ODAM	odontogenic, ameloblast asssociated
chr4_+_74498042	0.360		ALB	albumin
chr2_-_88946767	0.342
chr4_+_89115862	0.341		SPP1	secreted phosphoprotein 1
chr2_+_170259195	0.340	NM_144711 NM_001008489	PHOSPHO2-KLHL23 KLHL23 PHOSPHO2	PHOSPHO2-KLHL23 read-through transcript kelch-like 23 (Drosophila) phosphatase, orphan 2
chr6_+_144654565	0.339	NM_007124	UTRN	utrophin
chr14_+_94148466	0.338	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr17_-_53849929	0.337	NM_017763	RNF43	ring finger protein 43
chr3_-_180467483	0.330	NM_001163677 NM_171828	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_-_8668723	0.328	NM_015931	C3orf32	chromosome 3 open reading frame 32
chr18_+_53865455	0.327	NM_001144964	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chrX_-_131375217	0.325	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr12_+_21059896	0.324	NM_001009562	LST-3TM12	organic anion transporter LST-3b
chr16_-_71650034	0.323	NM_001164766	ZFHX3	zinc finger homeobox 3
chr3_+_52803823	0.313	NM_002217	ITIH3	inter-alpha (globulin) inhibitor H3
chr22_+_21340757	0.305
chr22_-_29290875	0.304	NM_004861	GAL3ST1	galactose-3-O-sulfotransferase 1
chr15_-_58706934	0.304	NM_002943 NM_134260	RORA	RAR-related orphan receptor A
chr12_-_9804682	0.298	NM_001781	CD69	CD69 molecule
chr2_-_188127430	0.298	NM_001032281 NM_006287	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr8_+_97575052	0.294	NM_002998	SDC2	syndecan 2
chr8_-_17797127	0.293	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr7_+_133862883	0.293	NM_020299	AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)
chrM_+_1670	0.291		USP47	ubiquitin specific peptidase 47
chr4_+_89115892	0.290		SPP1	secreted phosphoprotein 1
chr12_+_887272	0.284		WNK1	WNK lysine deficient protein kinase 1
chr3_+_187813553	0.284		AHSG	alpha-2-HS-glycoprotein
chrX_-_76824726	0.283		ATRX	alpha thalassemia/mental retardation syndrome X-linked
chr3_-_147451509	0.281		PLSCR4	phospholipid scramblase 4
chr11_-_118405288	0.280	NM_001164280	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr16_+_20682812	0.277	NM_005622 NM_202000	ACSM3	acyl-CoA synthetase medium-chain family member 3
chr10_+_57028755	0.275	NM_001190478	MTRNR2L5	MT-RNR2-like 5
chr8_+_97575071	0.264		SDC2	syndecan 2
chr19_-_40996040	0.263	NM_021232	PRODH2	proline dehydrogenase (oxidase) 2
chr20_+_35445350	0.262		SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr8_-_38127489	0.260	NM_000349	STAR	steroidogenic acute regulatory protein
chr3_-_13359746	0.259		NUP210	nucleoporin 210kDa
chr15_+_39839866	0.259		MGA	MAX gene associated
chr6_+_52637116	0.257		LOC730101	hypothetical LOC730101
chr7_+_94135384	0.256		PEG10	paternally expressed 10
chrX_+_15435351	0.252	NM_001721	BMX	BMX non-receptor tyrosine kinase
chr16_+_68284252	0.251		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_111217244	0.251	NM_000560	CD53	CD53 molecule
chr1_+_210805319	0.246	NM_001030287	ATF3	activating transcription factor 3
chr12_+_13240983	0.245		EMP1	epithelial membrane protein 1
chr12_-_8110268	0.244		C3AR1	complement component 3a receptor 1
chr11_+_60727559	0.243	NM_001079807	PGA3 PGA4	pepsinogen 3, group I (pepsinogen A) pepsinogen 4, group I (pepsinogen A)
chr3_+_134978615	0.241		TF	transferrin
chr3_+_187813538	0.238	NM_001622	AHSG	alpha-2-HS-glycoprotein
chrX_-_2896285	0.237		ARSE	arylsulfatase E (chondrodysplasia punctata 1)
chr19_-_52427698	0.236	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr2_+_138438277	0.235	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr16_-_45562840	0.234		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr16_-_48960186	0.233	NM_001173984 NM_013263	BRD7	bromodomain containing 7
chr4_-_40212670	0.232	NM_019027	RBM47	RNA binding motif protein 47
chr6_+_31623370	0.231		NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr4_+_74497998	0.231		ALB	albumin
chr12_-_7979896	0.229	NM_006931	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3
chr3_-_195553297	0.228	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr6_+_31623331	0.228	NM_001144961 NM_005007	NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr22_+_19458378	0.225	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr22_+_21464980	0.225
chr2_+_176761552	0.225	NM_024501	HOXD1	homeobox D1
chr6_+_32515596	0.224	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr16_-_24876357	0.223		ARHGAP17	Rho GTPase activating protein 17
chr4_+_89115825	0.221	NM_000582 NM_001040058 NM_001040060	SPP1	secreted phosphoprotein 1
chr4_-_70115037	0.221	NM_001073	UGT2B11	UDP glucuronosyltransferase 2 family, polypeptide B11
chr16_+_28850760	0.221	NM_001178098 NM_001770	CD19	CD19 molecule
chr16_-_29817841	0.221	NM_001114099 NM_001114100 NM_012410 NM_201575	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr8_-_6407882	0.220	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr7_+_45899621	0.218
chr3_-_58175437	0.217	NM_004944	DNASE1L3	deoxyribonuclease I-like 3
chr1_-_167822334	0.216	NM_000130	F5	coagulation factor V (proaccelerin, labile factor)
chr10_-_64698831	0.216	NM_004241	JMJD1C	jumonji domain containing 1C
chr7_+_137411717	0.216	NM_001190906 NM_001190907 NM_005989	AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
chr1_-_159275334	0.214		TSTD1	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr7_-_149960218	0.213		GIMAP6	GTPase, IMAP family member 6
chr3_-_147451648	0.208	NM_001128306 NM_001177304 NM_020353	PLSCR4	phospholipid scramblase 4
chr1_-_159275357	0.208	NM_001113205 NM_001113206 NM_001113207	TSTD1 F11R	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 F11 receptor
chr12_-_9159707	0.207		A2M	alpha-2-macroglobulin
chr6_-_150109324	0.204	NM_198887	NUP43	nucleoporin 43kDa
chr6_+_32713160	0.204	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr8_-_19504285	0.203	NM_001130518	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr21_-_14840506	0.202	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr5_+_92944680	0.202	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr14_+_63750611	0.199	NM_182913	SYNE2	spectrin repeat containing, nuclear envelope 2
chr18_-_65775139	0.199	NM_006566	CD226	CD226 molecule
chr8_-_101384633	0.197	NM_015435	RNF19A	ring finger protein 19A
chr22_+_21543671	0.195		IGLV4-3	immunoglobulin lambda variable 4-3
chr11_-_5247948	0.195	NM_005330	HBE1	hemoglobin, epsilon 1
chr8_+_123863224	0.194		ZHX2	zinc fingers and homeoboxes 2
chr15_+_56511466	0.193	NM_000236	LIPC	lipase, hepatic
chr17_-_31441390	0.192	NM_002983	CCL3	chemokine (C-C motif) ligand 3
chr4_+_74499651	0.190		ALB	albumin
chr8_-_81155564	0.189	NM_001025252	TPD52	tumor protein D52
chr14_+_75058518	0.189	NM_006399	BATF	basic leucine zipper transcription factor, ATF-like
chr4_-_140280031	0.187	NM_201999	ELF2	E74-like factor 2 (ets domain transcription factor)
chr6_-_11340887	0.185	NM_006403 NM_182966	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr15_-_35178888	0.185	NM_172316	MEIS2	Meis homeobox 2
chr1_+_111217314	0.184		CD53	CD53 molecule
chr9_+_102987137	0.184	NM_017753	LPPR1	lipid phosphate phosphatase-related protein type 1
chr4_+_187424111	0.179	NM_000128	F11	coagulation factor XI
chr12_-_8110196	0.178	NM_004054	C3AR1	complement component 3a receptor 1
chr14_+_75058591	0.178		BATF	basic leucine zipper transcription factor, ATF-like
chr6_-_11340886	0.177		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr16_+_49288550	0.177	NM_022162	NOD2	nucleotide-binding oligomerization domain containing 2
chr12_-_45506001	0.176	NM_001143824 NM_018018	SLC38A4	solute carrier family 38, member 4
chr1_-_24342158	0.175	NM_021258	IL22RA1	interleukin 22 receptor, alpha 1
chr1_-_9040141	0.174		SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr3_+_63859114	0.170	NM_001177387	ATXN7	ataxin 7
chr3_+_123256902	0.168	NM_175862	CD86	CD86 molecule
chr9_+_79158164	0.168		VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr10_-_69267774	0.167	NM_021800 NM_201262	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr4_-_89963177	0.167	NM_001015045	FAM13A	family with sequence similarity 13, member A
chr2_+_143351695	0.166		KYNU	kynureninase
chr1_+_32512298	0.166	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase
chr12_-_9159742	0.165		A2M	alpha-2-macroglobulin
chr1_-_180624380	0.164		GLUL	glutamate-ammonia ligase
chr2_+_88966170	0.160
chr6_+_167445284	0.158	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr2_-_188127294	0.156		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr3_+_143824955	0.155	NM_002670	PLS1	plastin 1
chr16_-_29797172	0.155		SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr2_+_33514896	0.154	NM_170672	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_-_11340869	0.154		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr15_-_78050515	0.153	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr20_-_45360903	0.152		ZMYND8	zinc finger, MYND-type containing 8
chr15_-_32416336	0.152	NM_001042497 NM_133647	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr8_+_86287161	0.152	NM_001083589	E2F5	E2F transcription factor 5, p130-binding
chr15_-_35179185	0.151		MEIS2	Meis homeobox 2
chr13_+_30207668	0.151	NM_001629	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr17_+_50697319	0.151	NM_002126	HLF	hepatic leukemia factor
chr17_-_53950191	0.151	NM_004687	MTMR4	myotubularin related protein 4
chr16_-_51139214	0.151	NM_001146188	TOX3	TOX high mobility group box family member 3
chr15_-_91078307	0.150		FAM174B	family with sequence similarity 174, member B
chr4_+_41309482	0.150		LIMCH1	LIM and calponin homology domains 1
chr6_+_31622606	0.149	NM_001144962 NM_001144963	NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr2_-_144991386	0.149		ZEB2	zinc finger E-box binding homeobox 2
chr10_-_44794146	0.149	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr12_-_49708279	0.147	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr10_+_101532450	0.147	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_-_149960612	0.147	NM_024711	GIMAP6	GTPase, IMAP family member 6
chr13_-_47885248	0.147		LPAR6	lysophosphatidic acid receptor 6
chr11_+_59580630	0.146	NM_001031666 NM_001031809 NM_006138	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr12_-_9159780	0.143		A2M	alpha-2-macroglobulin
chr7_-_115458064	0.143		TFEC	transcription factor EC
chr4_+_41309690	0.140		LIMCH1	LIM and calponin homology domains 1
chrX_-_43626537	0.139	NM_000898	MAOB	monoamine oxidase B
chr10_+_102722275	0.139	NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_159546348	0.137	NM_000530	MPZ	myelin protein zero
chr1_-_180624494	0.137		GLUL	glutamate-ammonia ligase
chr2_-_88208650	0.137	NM_001443	FABP1	fatty acid binding protein 1, liver
chr11_+_59580705	0.136		MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr8_-_125649926	0.132		MTSS1	metastasis suppressor 1
chr22_-_37214480	0.132	NM_001098505 NM_030881	DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chrY_+_15145019	0.132	NM_014893	NLGN4Y	neuroligin 4, Y-linked
chr4_-_90197140	0.129	NM_014883	FAM13A	family with sequence similarity 13, member A
chr17_-_36451189	0.129	NM_030967	KRTAP1-3 KRTAP1-1	keratin associated protein 1-3 keratin associated protein 1-1
chr6_-_116529101	0.128		LOC100287673	hypothetical LOC100287673
chr13_-_47885653	0.128	NM_001162498	LPAR6	lysophosphatidic acid receptor 6

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.52	5.34e-04	GO:0050865	regulation of cell activation
2.56	5.62e-04	GO:0002694	regulation of leukocyte activation
1.69	2.93e-03	GO:0009611	response to wounding
1.99	5.09e-03	GO:0050776	regulation of immune response
1.98	7.34e-03	GO:0002684	positive regulation of immune system process
1.76	8.80e-03	GO:0002682	regulation of immune system process
8.33	1.25e-02	GO:0046640	regulation of alpha-beta T cell proliferation
1.23	1.31e-02	GO:0032501	multicellular organismal process
1.52	1.78e-02	GO:0002376	immune system process
2.56	1.83e-02	GO:0050863	regulation of T cell activation
2.49	2.19e-02	GO:0050867	positive regulation of cell activation
2.33	3.93e-02	GO:0051249	regulation of lymphocyte activation
2.44	4.55e-02	GO:0002696	positive regulation of leukocyte activation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.28	1.61e-03	GO:0071944	cell periphery
1.28	2.25e-03	GO:0005886	plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.53	2.92e-02	GO:0015171	amino acid transmembrane transporter activity
3.23	4.26e-02	GO:0005275	amine transmembrane transporter activity