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• Activity deltas table
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Motif ID: HIC1.p2

Z-value: 5.528

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_224612177	10.688	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr11_+_101485946	9.527	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr2_-_160972606	9.217		RBMS1	RNA binding motif, single stranded interacting protein 1
chr2_-_224611568	8.984	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr13_-_109757442	8.960	NM_001845	COL4A1	collagen, type IV, alpha 1
chr1_-_85703198	7.927		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr13_+_109757593	7.246	NM_001846	COL4A2	collagen, type IV, alpha 2
chr1_-_20685314	7.213	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr11_-_11987458	7.014	NM_013253	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr11_-_11987414	6.961		DKK3	dickkopf homolog 3 (Xenopus laevis)
chr13_+_97593711	6.722		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_+_235525355	6.417	NM_014521	SH3BP4	SH3-domain binding protein 4
chr8_+_26491317	6.336	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chr10_+_124124196	6.270		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr10_+_124211353	6.165		HTRA1	HtrA serine peptidase 1
chr11_-_11987198	5.920	NM_015881	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr11_-_11987115	5.757		DKK3	dickkopf homolog 3 (Xenopus laevis)
chr4_-_177950658	5.678	NM_005429	VEGFC	vascular endothelial growth factor C
chr2_+_9264327	5.670	NM_001135191 NM_003887	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr13_-_39075304	5.644		LHFP	lipoma HMGIC fusion partner
chr1_-_223907283	5.614	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr2_+_9264360	5.604		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr10_+_124210980	5.591	NM_002775	HTRA1	HtrA serine peptidase 1
chr13_+_97593469	5.430		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr15_+_99237527	5.272	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr3_-_187025501	5.267	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr1_-_95165037	5.213		CNN3	calponin 3, acidic
chr12_-_123023052	5.183	NM_025140	CCDC92	coiled-coil domain containing 92
chr16_-_4106186	5.167	NM_001116	ADCY9	adenylate cyclase 9
chrX_+_9943793	5.098	NM_015691	WWC3	WWC family member 3
chr14_+_105012106	5.089	NM_001312	CRIP2	cysteine-rich protein 2
chr7_+_129919157	4.992	NM_002402	MEST	mesoderm specific transcript homolog (mouse)
chr1_-_95165089	4.846	NM_001839	CNN3	calponin 3, acidic
chr17_-_74433048	4.816	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr13_+_26029879	4.807		WASF3	WAS protein family, member 3
chr16_-_4106022	4.766		ADCY9	adenylate cyclase 9
chr2_-_235070431	4.730	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr2_-_1727247	4.711		PXDN	peroxidasin homolog (Drosophila)
chr14_+_104402626	4.641	NM_001112726 NM_015005	KIAA0284	KIAA0284
chr11_+_86189138	4.637	NM_007173	PRSS23	protease, serine, 23
chr8_-_41286088	4.586	NM_003012	SFRP1	secreted frizzled-related protein 1
chr2_-_1727292	4.535	NM_012293	PXDN	peroxidasin homolog (Drosophila)
chr1_-_94475504	4.535		ARHGAP29	Rho GTPase activating protein 29
chr3_-_151171190	4.489	NM_002628 NM_053024	PFN2	profilin 2
chr13_+_113546943	4.460		GAS6	growth arrest-specific 6
chrX_+_135057202	4.458	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr2_+_101680594	4.434	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_74432800	4.413		TIMP2	TIMP metallopeptidase inhibitor 2
chr12_-_105165805	4.352	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr1_+_19843261	4.320	NM_005380	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr1_-_94475840	4.307	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr8_+_22492586	4.274		PDLIM2	PDZ and LIM domain 2 (mystique)
chr18_+_7557313	4.273	NM_001105244 NM_002845	PTPRM	protein tyrosine phosphatase, receptor type, M
chr9_-_13269562	4.271		MPDZ	multiple PDZ domain protein
chr9_-_87904306	4.237	NM_016548	GOLM1	golgi membrane protein 1
chr17_-_74432671	4.232		TIMP2	TIMP metallopeptidase inhibitor 2
chr2_+_46377952	4.197	NM_001430	EPAS1	endothelial PAS domain protein 1
chr8_-_48813236	4.185		CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr2_-_161058120	4.162		RBMS1	RNA binding motif, single stranded interacting protein 1
chr1_+_181258952	4.132	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr13_+_113546841	4.088	NM_000820	GAS6	growth arrest-specific 6
chr2_-_175578156	4.069	NM_001025201 NM_001822	CHN1	chimerin (chimaerin) 1
chr13_+_113546912	4.024		GAS6	growth arrest-specific 6
chrX_-_152804731	4.021		L1CAM	L1 cell adhesion molecule
chr21_+_41461962	4.013		BACE2	beta-site APP-cleaving enzyme 2
chr10_-_13381751	3.993	NM_001037537	PHYH	phytanoyl-CoA 2-hydroxylase
chr1_-_56817717	3.988		PPAP2B	phosphatidic acid phosphatase type 2B
chr20_+_4614796	3.984	NM_000311 NM_001080121 NM_001080122 NM_183079 NM_001080123	PRNP	prion protein
chr8_-_119192985	3.950	NM_000127	EXT1	exostosin 1
chr1_-_56817823	3.948	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr13_-_39075355	3.930	NM_005780	LHFP	lipoma HMGIC fusion partner
chr10_-_17699371	3.929	NM_014241	PTPLA	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_-_139060285	3.927		NPDC1	neural proliferation, differentiation and control, 1
chr10_-_17699309	3.884		PTPLA	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_-_139060377	3.853		NPDC1	neural proliferation, differentiation and control, 1
chr1_-_56817568	3.847		PPAP2B	phosphatidic acid phosphatase type 2B
chr13_-_39075200	3.840		LHFP	lipoma HMGIC fusion partner
chr7_-_24763556	3.812		DFNA5	deafness, autosomal dominant 5
chr13_+_113546897	3.794		GAS6	growth arrest-specific 6
chr13_+_26029799	3.789	NM_006646	WASF3	WAS protein family, member 3
chr1_-_85703321	3.757	NM_012137	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr6_+_72055235	3.738		OGFRL1	opioid growth factor receptor-like 1
chr10_+_124124083	3.718	NM_001001974	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr7_-_29995809	3.702	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr4_-_52599181	3.684	NM_000232	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr3_-_126088819	3.663	NM_002213	ITGB5	integrin, beta 5
chr7_-_24763577	3.631	NM_001127453	DFNA5	deafness, autosomal dominant 5
chr22_+_31527678	3.588		TIMP3	TIMP metallopeptidase inhibitor 3
chr5_+_92946348	3.575		NR2F1	nuclear receptor subfamily 2, group F, member 1
chr5_-_16989371	3.565	NM_012334	MYO10	myosin X
chr11_+_19691397	3.490	NM_145117 NM_182964	NAV2	neuron navigator 2
chr21_+_45649719	3.416
chr13_+_47705493	3.394		ITM2B	integral membrane protein 2B
chr6_+_72055197	3.393	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr1_+_221966835	3.376		CAPN2	calpain 2, (m/II) large subunit
chr15_-_20637731	3.373	NM_144599	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr7_+_129918408	3.327	NM_177525	MEST	mesoderm specific transcript homolog (mouse)
chr3_-_147361465	3.318		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr15_+_99237555	3.310		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr9_+_132309914	3.288	NM_000050 NM_054012	ASS1	argininosuccinate synthase 1
chr6_+_72055229	3.279		OGFRL1	opioid growth factor receptor-like 1
chr5_-_122400312	3.263	NM_000943	PPIC	peptidylprolyl isomerase C (cyclophilin C)
chr10_-_15453060	3.260	NM_001010924	FAM171A1	family with sequence similarity 171, member A1
chr5_+_76150588	3.241	NM_005242	F2RL1	coagulation factor II (thrombin) receptor-like 1
chr17_-_72218661	3.239		MXRA7	matrix-remodelling associated 7
chr21_-_26465005	3.231	NM_000484 NM_001136129 NM_001136130 NM_201413 NM_201414	APP	amyloid beta (A4) precursor protein
chr16_-_62573	3.210	NM_022450	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr9_-_139060416	3.182	NM_015392	NPDC1	neural proliferation, differentiation and control, 1
chr4_-_57671112	3.177		IGFBP7	insulin-like growth factor binding protein 7
chr3_+_61522219	3.159	NM_002841	PTPRG	protein tyrosine phosphatase, receptor type, G
chr1_+_98899734	3.137	NM_015976 NM_152238	SNX7	sorting nexin 7
chr18_-_20231709	3.077		OSBPL1A	oxysterol binding protein-like 1A
chr9_-_87904215	3.077		GOLM1	golgi membrane protein 1
chr9_-_87904280	3.069		GOLM1	golgi membrane protein 1
chr22_+_31527744	3.054		TIMP3	TIMP metallopeptidase inhibitor 3
chr17_-_72218535	3.051	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr7_-_24763841	3.038		DFNA5	deafness, autosomal dominant 5
chr14_+_54104383	3.028	NM_001161576 NM_015589	SAMD4A	sterile alpha motif domain containing 4A
chr18_+_19523526	3.023	NM_001127717 NM_198129	LAMA3	laminin, alpha 3
chr21_+_41461924	3.022		BACE2	beta-site APP-cleaving enzyme 2
chr18_-_24011349	3.012	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_1727324	2.994		PXDN	peroxidasin homolog (Drosophila)
chr12_+_3056781	2.975	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr2_-_56004366	2.962	NM_001039348 NM_001039349	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1
chr2_+_36436873	2.946	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr20_+_11819364	2.896	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr14_-_104515738	2.886	NM_138420	AHNAK2	AHNAK nucleoprotein 2
chr8_-_48813256	2.873	NM_005195	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr10_+_120853548	2.863		FAM45A	family with sequence similarity 45, member A
chr8_+_26491383	2.863		DPYSL2	dihydropyrimidinase-like 2
chr20_-_55718351	2.842	NM_020182	PMEPA1	prostate transmembrane protein, androgen induced 1
chr12_-_123023312	2.830		CCDC92	coiled-coil domain containing 92
chr21_+_45649429	2.828	NM_130445	COL18A1	collagen, type XVIII, alpha 1
chr2_-_112907577	2.791	NM_001164463	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr3_-_187025438	2.782		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr7_+_79602023	2.754	NM_002069	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr8_-_27528105	2.739		CLU	clusterin
chr21_+_41461597	2.725	NM_012105 NM_138991 NM_138992	BACE2	beta-site APP-cleaving enzyme 2
chr15_+_94674849	2.716	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr18_-_20105814	2.700		OSBPL1A	oxysterol binding protein-like 1A
chr3_-_126257425	2.672	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr10_+_120853600	2.669	NM_207009	FAM45A	family with sequence similarity 45, member A
chr1_+_85819004	2.661	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr1_-_56817802	2.639		PPAP2B	phosphatidic acid phosphatase type 2B
chr3_+_50167424	2.636		SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr15_-_20929658	2.634		HERC2P2	hect domain and RLD 2 pseudogene 2
chr9_+_123003549	2.628		GSN	gelsolin
chr2_+_173000552	2.626	NM_000210 NM_001079818	ITGA6	integrin, alpha 6
chr3_-_147451509	2.625		PLSCR4	phospholipid scramblase 4
chr5_-_122400219	2.617		PPIC	peptidylprolyl isomerase C (cyclophilin C)
chr12_+_6179736	2.605	NM_001769	CD9	CD9 molecule
chr8_-_17702665	2.599	NM_001001924 NM_001001925	MTUS1	microtubule associated tumor suppressor 1
chr19_+_16048266	2.597		TPM4	tropomyosin 4
chr1_+_167342149	2.587		ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_147361912	2.566	NM_000935 NM_182943	PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr12_-_108802561	2.540	NM_016433	GLTP	glycolipid transfer protein
chr11_+_129445017	2.538		APLP2	amyloid beta (A4) precursor-like protein 2
chr4_-_22126437	2.532	NM_145290	GPR125	G protein-coupled receptor 125
chr11_+_129445057	2.497		APLP2	amyloid beta (A4) precursor-like protein 2
chr3_-_151171576	2.496		PFN2	profilin 2
chr13_+_97593411	2.487	NM_001001715 NM_005766	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_147361626	2.471		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr5_+_76047536	2.467	NM_001992	F2R	coagulation factor II (thrombin) receptor
chr3_+_57969127	2.450	NM_001164317 NM_001164318 NM_001164319 NM_001457	FLNB	filamin B, beta
chr3_-_147451648	2.449	NM_001128306 NM_001177304 NM_020353	PLSCR4	phospholipid scramblase 4
chr5_-_57791544	2.449	NM_006622	PLK2	polo-like kinase 2
chr1_+_221966849	2.418		CAPN2	calpain 2, (m/II) large subunit
chr2_-_165406173	2.416	NM_014900	COBLL1	COBL-like 1
chr17_+_75689985	2.392		GAA	glucosidase, alpha; acid
chr15_-_81744469	2.389	NM_001717	BNC1	basonuclin 1
chr17_-_60088773	2.384	NM_022739	SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr17_-_60088459	2.376		SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr8_-_27528215	2.371	NM_001831	CLU	clusterin
chr18_-_20231783	2.363	NM_080597	OSBPL1A	oxysterol binding protein-like 1A
chr21_+_17807167	2.361	NM_001338	CXADR	coxsackie virus and adenovirus receptor
chr2_+_200879737	2.357		SPATS2L	spermatogenesis associated, serine-rich 2-like
chr19_-_4351470	2.348	NM_003025	SH3GL1	SH3-domain GRB2-like 1
chr7_-_150960086	2.344	NM_024429	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr5_+_52812165	2.343		FST	follistatin
chr19_+_16048306	2.342		TPM4	tropomyosin 4
chr9_+_123070276	2.321		GSN	gelsolin
chr9_+_123070191	2.319	NM_001127662 NM_001127663 NM_001127664 NM_001127665 NM_001127666 NM_001127667 NM_198252	GSN	gelsolin
chr11_+_13255913	2.314		ARNTL	aryl hydrocarbon receptor nuclear translocator-like
chr3_-_49370755	2.312	NM_000581 NM_201397	GPX1	glutathione peroxidase 1
chr16_-_10581944	2.298	NM_001424	EMP2	epithelial membrane protein 2
chr14_-_51605461	2.290		NID2	nidogen 2 (osteonidogen)
chr17_-_829655	2.288	NM_022463	NXN	nucleoredoxin
chr5_-_146869811	2.274	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chr11_+_13255836	2.267	NM_001030272 NM_001030273 NM_001178	ARNTL	aryl hydrocarbon receptor nuclear translocator-like
chr4_+_184257337	2.266	NM_024949	WWC2	WW and C2 domain containing 2
chr12_-_107775462	2.263	NM_001161330 NM_018984	SSH1	slingshot homolog 1 (Drosophila)
chr5_+_76150637	2.262		F2RL1	coagulation factor II (thrombin) receptor-like 1
chr1_-_43691932	2.260		HYI	hydroxypyruvate isomerase (putative)
chr6_-_52549774	2.256	NM_012288	TRAM2	translocation associated membrane protein 2
chr14_+_85069217	2.247
chr18_-_490583	2.246	NM_130386	COLEC12	collectin sub-family member 12
chr11_-_2907169	2.239	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr12_-_15833617	2.233	NM_004447	EPS8	epidermal growth factor receptor pathway substrate 8
chr22_+_36928011	2.230		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr3_-_121652183	2.226	NM_007085	FSTL1	follistatin-like 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.37	1.26e-15	GO:0048869	cellular developmental process
1.37	1.23e-14	GO:0030154	cell differentiation
1.71	1.77e-14	GO:0000902	cell morphogenesis
1.77	2.15e-14	GO:0032990	cell part morphogenesis
1.58	2.25e-14	GO:0048699	generation of neurons
1.76	3.79e-14	GO:0048858	cell projection morphogenesis
1.67	5.52e-14	GO:0030030	cell projection organization
1.56	6.18e-14	GO:0022008	neurogenesis
1.66	2.13e-13	GO:0032989	cellular component morphogenesis
1.41	4.13e-13	GO:0009653	anatomical structure morphogenesis
1.74	5.45e-13	GO:0000904	cell morphogenesis involved in differentiation
1.76	1.76e-12	GO:0048812	neuron projection morphogenesis
1.53	2.22e-12	GO:0048468	cell development
1.61	2.33e-12	GO:0030182	neuron differentiation
1.71	7.00e-12	GO:0031175	neuron projection development
1.76	8.98e-12	GO:0007409	axonogenesis
1.65	1.24e-11	GO:0048666	neuron development
1.74	1.35e-11	GO:0048667	cell morphogenesis involved in neuron differentiation
1.22	2.94e-11	GO:0032502	developmental process
1.82	8.47e-11	GO:0007411	axon guidance
1.23	9.04e-11	GO:0007275	multicellular organismal development
1.38	1.44e-10	GO:0007399	nervous system development
1.22	9.68e-09	GO:0048856	anatomical structure development
1.35	3.50e-08	GO:0009966	regulation of signal transduction
1.31	1.27e-07	GO:0023051	regulation of signaling
1.22	2.12e-07	GO:0048731	system development
1.41	8.13e-07	GO:0040011	locomotion
1.47	1.08e-06	GO:0007167	enzyme linked receptor protein signaling pathway
2.14	1.21e-06	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.12	1.97e-06	GO:0022604	regulation of cell morphogenesis
1.14	1.83e-05	GO:0032501	multicellular organismal process
1.49	3.76e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.50	4.73e-05	GO:0072358	cardiovascular system development
1.50	4.73e-05	GO:0072359	circulatory system development
1.48	5.69e-05	GO:0006935	chemotaxis
1.48	5.69e-05	GO:0042330	taxis
1.63	1.13e-04	GO:0001944	vasculature development
1.62	1.42e-04	GO:0060284	regulation of cell development
1.19	2.10e-04	GO:0071842	cellular component organization at cellular level
1.58	2.54e-04	GO:0051056	regulation of small GTPase mediated signal transduction
1.93	4.75e-04	GO:0010975	regulation of neuron projection development
1.27	4.76e-04	GO:0035556	intracellular signal transduction
1.59	4.83e-04	GO:0051270	regulation of cellular component movement
2.26	5.28e-04	GO:0050770	regulation of axonogenesis
1.68	7.50e-04	GO:0046578	regulation of Ras protein signal transduction
1.40	1.08e-03	GO:0042060	wound healing
1.82	1.13e-03	GO:0031344	regulation of cell projection organization
1.22	1.17e-03	GO:0048583	regulation of response to stimulus
1.59	1.42e-03	GO:0001568	blood vessel development
1.57	1.61e-03	GO:0040012	regulation of locomotion
1.56	2.44e-03	GO:0022603	regulation of anatomical structure morphogenesis
1.45	3.17e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.50	4.30e-03	GO:0007264	small GTPase mediated signal transduction
1.32	4.68e-03	GO:0009888	tissue development
1.56	5.93e-03	GO:0030334	regulation of cell migration
1.14	6.45e-03	GO:0016043	cellular component organization
1.84	6.97e-03	GO:0030111	regulation of Wnt receptor signaling pathway
1.55	9.18e-03	GO:2000145	regulation of cell motility
1.33	1.05e-02	GO:2000026	regulation of multicellular organismal development
1.59	1.19e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.90	1.24e-02	GO:0035023	regulation of Rho protein signal transduction
1.65	1.37e-02	GO:0045664	regulation of neuron differentiation
1.27	1.55e-02	GO:0010646	regulation of cell communication
1.43	1.69e-02	GO:0016477	cell migration
1.27	1.73e-02	GO:0008104	protein localization
1.34	1.79e-02	GO:0045595	regulation of cell differentiation
1.57	1.88e-02	GO:0050767	regulation of neurogenesis
1.54	1.89e-02	GO:0051960	regulation of nervous system development
1.08	1.90e-02	GO:0050794	regulation of cellular process
1.27	2.13e-02	GO:0032879	regulation of localization
1.16	2.28e-02	GO:0071841	cellular component organization or biogenesis at cellular level
1.28	3.40e-02	GO:0050793	regulation of developmental process
1.84	3.63e-02	GO:0010720	positive regulation of cell development
1.17	3.70e-02	GO:0048523	negative regulation of cellular process
1.29	4.01e-02	GO:0051128	regulation of cellular component organization
1.57	4.04e-02	GO:0048514	blood vessel morphogenesis
1.43	4.07e-02	GO:0090066	regulation of anatomical structure size

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.14	3.82e-11	GO:0070161	anchoring junction
2.15	5.91e-10	GO:0005912	adherens junction
1.96	2.62e-08	GO:0031252	cell leading edge
1.09	4.00e-07	GO:0005737	cytoplasm
1.51	4.25e-07	GO:0030054	cell junction
1.30	1.31e-06	GO:0005856	cytoskeleton
1.11	1.57e-06	GO:0016020	membrane
1.36	1.70e-06	GO:0005794	Golgi apparatus
2.10	9.48e-06	GO:0005925	focal adhesion
2.05	1.79e-05	GO:0005924	cell-substrate adherens junction
2.01	3.22e-05	GO:0030055	cell-substrate junction
1.60	4.14e-05	GO:0015629	actin cytoskeleton
2.30	4.31e-05	GO:0031256	leading edge membrane
1.43	5.44e-05	GO:0044431	Golgi apparatus part
1.34	1.48e-04	GO:0042995	cell projection
1.46	2.00e-04	GO:0000139	Golgi membrane
1.66	1.99e-03	GO:0005911	cell-cell junction
1.09	2.39e-03	GO:0044444	cytoplasmic part
1.94	6.31e-03	GO:0030027	lamellipodium
1.82	9.80e-03	GO:0019898	extrinsic to membrane
1.28	1.25e-02	GO:0031982	vesicle
1.72	1.61e-02	GO:0031253	cell projection membrane
1.28	1.89e-02	GO:0031410	cytoplasmic vesicle
1.12	2.25e-02	GO:0071944	cell periphery
1.04	4.97e-02	GO:0005622	intracellular

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.54	9.85e-08	GO:0008092	cytoskeletal protein binding
1.52	2.39e-05	GO:0030695	GTPase regulator activity
1.59	4.28e-05	GO:0003779	actin binding
1.50	4.92e-05	GO:0060589	nucleoside-triphosphatase regulator activity
1.57	7.39e-04	GO:0005083	small GTPase regulator activity
1.08	3.55e-03	GO:0005515	protein binding
1.91	1.68e-02	GO:0005088	Ras guanyl-nucleotide exchange factor activity
2.00	2.89e-02	GO:0005089	Rho guanyl-nucleotide exchange factor activity
1.64	3.88e-02	GO:0005085	guanyl-nucleotide exchange factor activity