Motif ID: HNF1A.p2

Z-value: 6.308


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF1Achr12_+_1199009310.977.9e-10Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_105169370 37.330 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr17_-_61655915 32.187 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_74520796 30.525 NM_001134
AFP
alpha-fetoprotein
chr4_+_74488910 28.807 ALB
albumin
chr4_+_74488947 28.438 ALB
albumin
chr14_-_93924663 27.328 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_93924873 26.299 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_+_74488835 25.762 NM_000477
ALB
albumin
chr4_+_74497998 24.922 ALB
albumin
chr7_+_45894480 23.515 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr4_+_74498042 20.974 ALB
albumin
chr11_+_46697345 20.348 F2
coagulation factor II (thrombin)
chr4_-_155731288 20.277 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr4_-_110942576 19.547 CFI
complement factor I
chr8_-_17797127 18.899 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr14_-_93859394 18.702 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr19_-_40995606 18.665 PRODH2
proline dehydrogenase (oxidase) 2
chr9_-_122852356 17.859 NM_001735
C5
complement component 5
chr11_+_46697312 17.830 NM_000506
F2
coagulation factor II (thrombin)
chr6_+_31731667 17.308 APOM
apolipoprotein M
chr14_+_20226762 17.194 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr6_+_31731647 16.749 NM_019101
APOM
apolipoprotein M
chr4_-_110942783 16.714 NM_000204
CFI
complement factor I
chr19_-_40995564 15.590 PRODH2
proline dehydrogenase (oxidase) 2
chr1_+_205344200 14.304 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr19_-_53081383 13.883 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr19_+_11211282 13.618 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr10_+_5126556 13.591 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr15_+_56511466 13.484 NM_000236
LIPC
lipase, hepatic
chr10_+_5126613 13.382 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5126589 13.306 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_-_52315436 13.110 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr10_-_52315390 12.800 A1CF
APOBEC1 complementation factor
chr19_-_53081326 12.718 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr4_-_69852090 12.625 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr17_+_38306339 12.359 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr2_-_88208650 12.188 NM_001443
FABP1
fatty acid binding protein 1, liver
chr15_-_88150823 11.723 ANPEP
alanyl (membrane) aminopeptidase
chr4_+_155703581 11.581 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr17_+_1592879 11.485 NM_000934
NM_001165921
SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr14_-_93829347 10.644 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_93829309 10.381 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_93829113 10.301 NM_016186
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_69996780 10.275 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr14_+_94097513 10.233 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr18_+_27425727 9.910 NM_000371
TTR
transthyretin
chr10_+_101532450 9.775 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_-_47545717 9.763 NM_022748
TNS3
tensin 3
chr16_-_86527608 9.437 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr4_-_186970366 7.612 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr17_+_71065478 7.483 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr11_-_117200618 7.461 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr1_+_17779528 7.456 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_-_100359353 7.206 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chrX_+_70351773 7.137 NM_001097642
GJB1
gap junction protein, beta 1, 32kDa
chr10_+_101532544 6.804 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_+_205328834 6.683 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr8_-_17599438 6.631 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr21_-_46399900 6.420 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr4_+_74493918 6.264 ALB
albumin
chr2_+_101874765 6.259 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_70351812 6.195 GJB1
gap junction protein, beta 1, 32kDa
chr17_+_1593040 5.946 NM_001165920
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr4_-_70115037 5.727 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr8_+_21967008 5.684 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr2_+_101874809 5.206 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr19_-_44135166 5.146 NM_148169
FBXO17
F-box protein 17
chr7_-_50600536 5.143 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr7_-_44547382 5.107 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr7_+_94130673 5.058 PEG10
paternally expressed 10
chr6_-_26038817 5.042 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr4_+_187424111 4.953 NM_000128
F11
coagulation factor XI
chr19_+_50109416 4.820 APOC1
apolipoprotein C-I
chr5_-_147191334 4.783 SPINK1
serine peptidase inhibitor, Kazal type 1
chr5_+_175908948 4.740 NM_017675
CDHR2
cadherin-related family member 2
chr6_+_167624792 4.627 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr19_-_40996040 4.332 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr2_-_168812132 4.265 NM_013233
STK39
serine threonine kinase 39
chr2_+_27573206 4.206 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr20_-_17589122 3.938 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chrX_-_131375217 3.919 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr5_-_147191428 3.912 NM_003122
SPINK1
serine peptidase inhibitor, Kazal type 1
chr2_+_62787534 3.499 NM_001142614
EHBP1
EH domain binding protein 1
chr1_-_228916486 3.386 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr5_+_176446425 3.314 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr16_+_88224175 3.294 DPEP1
dipeptidase 1 (renal)
chrX_+_107569671 3.250 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr6_+_158653679 3.158 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr17_-_202557 3.044 RPH3AL
rabphilin 3A-like (without C2 domains)
chr1_-_228916470 3.003 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr16_+_88224276 2.972 DPEP1
dipeptidase 1 (renal)
chr7_-_156494741 2.929 NM_001165255
MNX1
motor neuron and pancreas homeobox 1
chr6_+_161043214 2.610 NM_000301
NM_001168338
PLG

plasminogen

chr16_+_30118036 2.578 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr6_-_52736231 2.521 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr19_-_38052481 2.503 NM_001126335
NM_014270
SLC7A9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr17_-_202617 2.310 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr16_-_56393871 2.276 KIFC3
kinesin family member C3
chr14_+_38805251 2.268 NM_203356
CTAGE5
CTAGE family, member 5
chr6_+_64289585 2.195 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_-_25982418 2.063 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr8_-_18585721 2.001 PSD3
pleckstrin and Sec7 domain containing 3
chr4_+_124537334 1.964 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_12182641 1.950 LRP6
low density lipoprotein receptor-related protein 6
chr4_+_187424336 1.899 F11
coagulation factor XI
chr6_+_167456230 1.821 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr18_-_44723116 1.669 NM_001190823
SMAD7
SMAD family member 7
chr20_+_55569542 1.615 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr3_+_12367993 1.590 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr7_+_120416680 1.588 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr1_-_43196911 1.555 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr15_-_49184764 1.553 NM_207381
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr2_-_162638790 1.533 DPP4
dipeptidyl-peptidase 4
chr2_-_162639297 1.517 NM_001935
DPP4
dipeptidyl-peptidase 4
chrX_-_33056464 1.509 NM_004010
NM_004009
DMD

dystrophin

chr3_-_52269467 1.363 WDR82
WD repeat domain 82
chr20_+_35406497 1.356 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr22_-_41685827 1.330 NM_001184971
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr20_+_61841553 1.294 NM_020062
SLC2A4RG
SLC2A4 regulator
chr16_-_21344158 1.282 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr3_+_189425886 1.203 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_+_131936057 1.178 NM_000045
ARG1
arginase, liver
chr6_+_31815703 1.158 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6ORF26
MSH5



MSH5-C6orf26 read-through transcript
mutS homolog 5 (E. coli)



chr1_-_20014180 1.120 NM_019062
RNF186
ring finger protein 186
chr4_+_3413489 1.099 NM_001528
HGFAC
HGF activator
chr4_+_3413457 1.062 HGFAC
HGF activator
chr1_+_54132447 1.002 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr12_-_69838045 1.001 NM_004616
TSPAN8
tetraspanin 8
chr16_-_56393881 0.935 NM_001130100
NM_005550
KIFC3

kinesin family member C3

chr4_-_166253453 0.919 NM_001100389
TMEM192
transmembrane protein 192
chr7_+_129913271 0.903 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr16_+_20682812 0.896 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr17_-_8364942 0.886 MYH10
myosin, heavy chain 10, non-muscle
chr2_+_105799354 0.850 NCK2
NCK adaptor protein 2
chr1_+_81544432 0.836 LPHN2
latrophilin 2
chr4_-_166253374 0.796 TMEM192
transmembrane protein 192
chr15_+_22772545 0.790 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr9_+_79158164 0.780 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr6_+_155579788 0.764 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr2_+_108271526 0.759 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr20_-_4938913 0.739 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr6_-_109521969 0.737 NM_014454
SESN1
sestrin 1
chr16_+_22432344 0.684 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr5_-_78318112 0.667 NM_000046
ARSB
arylsulfatase B
chr3_-_152449591 0.643 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr20_+_2892918 0.636 PTPRA
protein tyrosine phosphatase, receptor type, A
chr16_-_56389176 0.627 NM_001130099
KIFC3
kinesin family member C3
chr14_+_54291255 0.616 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr17_-_53335748 0.587 NM_017949
CUEDC1
CUE domain containing 1
chr22_+_29696662 0.563


chr15_+_57691382 0.563 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_-_8695974 0.550 ST5
suppression of tumorigenicity 5
chr6_-_119512035 0.525 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr12_-_23993830 0.522 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr12_+_68419446 0.504 NM_175623
NM_175625
RAB3IP

RAB3A interacting protein (rabin3)

chr16_-_70763524 0.500 NM_031293
PMFBP1
polyamine modulated factor 1 binding protein 1
chr4_-_10295412 0.497 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr2_+_105834635 0.491 NM_001004720
NCK2
NCK adaptor protein 2
chr11_-_118405288 0.484 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr5_-_111121150 0.473 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr11_+_118561375 0.468 NM_001168468
NM_024791
PDZD3

PDZ domain containing 3

chr22_+_43476710 0.467 NM_181333
PRR5
proline rich 5 (renal)
chr3_-_193928038 0.460 NM_004113
FGF12
fibroblast growth factor 12
chr12_+_119900931 0.440 NM_000545
HNF1A
HNF1 homeobox A
chr4_-_74704964 0.439 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chrX_+_107174855 0.433 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr12_+_119900677 0.408 HNF1A
HNF1 homeobox A
chr11_+_43622348 0.407


chr20_+_41621119 0.395 SGK2
serum/glucocorticoid regulated kinase 2
chr17_+_41457394 0.384 MAPT
microtubule-associated protein tau
chr1_+_26973804 0.381 ARID1A
AT rich interactive domain 1A (SWI-like)
chr2_+_120487076 0.381 NM_001184938
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr1_-_203868622 0.366 NM_001973
NM_021795
ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr3_+_51550635 0.362 NM_015106
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr20_-_43972061 0.360 PLTP
phospholipid transfer protein
chr19_-_11500912 0.342 NM_001142464
NM_001142465
NM_016581
ECSIT


ECSIT homolog (Drosophila)


chr2_+_97696462 0.331 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr15_+_83724743 0.318 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr2_+_101981888 0.315 NM_173343
IL1R2
interleukin 1 receptor, type II
chr22_-_36836478 0.306 BAIAP2L2
BAI1-associated protein 2-like 2
chr17_+_69781980 0.302 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr3_+_151013126 0.291 NM_007282
NM_183381
RNF13

ring finger protein 13

chr20_+_42463279 0.290 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr21_-_33107813 0.285 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr6_+_54281161 0.274 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr20_+_61841662 0.268 SLC2A4RG
SLC2A4 regulator
chr3_+_63928459 0.262 NM_001128149
ATXN7
ataxin 7
chr3_+_101720753 0.262 TMEM45A
transmembrane protein 45A
chr1_+_178232379 0.251 CEP350
centrosomal protein 350kDa
chr5_-_111119846 0.238 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr3_-_121117647 0.233 GSK3B
glycogen synthase kinase 3 beta
chr6_+_131613196 0.231 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr2_-_1905508 0.224 MYT1L
myelin transcription factor 1-like
chr20_+_42463387 0.221 HNF4A
hepatocyte nuclear factor 4, alpha
chrX_-_21686079 0.207 NM_014332
SMPX
small muscle protein, X-linked
chr16_-_4836198 0.198 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chrY_+_1670485 0.168 NM_005088
AKAP17A
A kinase (PRKA) anchor protein 17A
chrX_+_1670485 0.168 NM_005088
AKAP17A
A kinase (PRKA) anchor protein 17A
chr12_-_112326037 0.167 NM_006843
SDS
serine dehydratase
chr7_-_107230867 0.163 NM_000111
SLC26A3
solute carrier family 26, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.03 1.17e-04 GO:0071702 organic substance transport
31.32 2.68e-04 GO:0051917 regulation of fibrinolysis
12.70 1.06e-03 GO:0030301 cholesterol transport
10.03 1.16e-03 GO:0033500 carbohydrate homeostasis
10.03 1.16e-03 GO:0042593 glucose homeostasis
12.37 1.27e-03 GO:0015918 sterol transport
9.85 1.34e-03 GO:0010951 negative regulation of endopeptidase activity
14.77 2.53e-03 GO:0030195 negative regulation of blood coagulation
34.46 2.94e-03 GO:0051918 negative regulation of fibrinolysis
14.26 3.15e-03 GO:0050819 negative regulation of coagulation
18.14 6.13e-03 GO:0034381 plasma lipoprotein particle clearance
5.89 7.62e-03 GO:0051346 negative regulation of hydrolase activity
12.16 8.41e-03 GO:0097006 regulation of plasma lipoprotein particle levels
51.68 1.22e-02 GO:0015712 hexose phosphate transport
51.68 1.22e-02 GO:0015760 glucose-6-phosphate transport
10.88 1.64e-02 GO:0030193 regulation of blood coagulation
8.32 1.98e-02 GO:0055088 lipid homeostasis
22.97 1.99e-02 GO:0030194 positive regulation of blood coagulation
5.27 2.07e-02 GO:0006869 lipid transport
8.04 2.48e-02 GO:0072376 protein activation cascade
10.09 2.58e-02 GO:0050818 regulation of coagulation
5.64 3.13e-02 GO:0030162 regulation of proteolysis
6.49 3.18e-02 GO:0010466 negative regulation of peptidase activity
2.61 3.63e-02 GO:0006082 organic acid metabolic process
19.69 3.93e-02 GO:0050820 positive regulation of coagulation
4.82 4.41e-02 GO:0010876 lipid localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.16 9.31e-05 GO:0045177 apical part of cell
5.59 2.67e-04 GO:0016324 apical plasma membrane
9.28 1.58e-03 GO:0031983 vesicle lumen
2.57 2.17e-03 GO:0005615 extracellular space
8.47 2.94e-03 GO:0031091 platelet alpha granule
8.80 9.59e-03 GO:0031093 platelet alpha granule lumen
8.62 1.08e-02 GO:0034774 secretory granule lumen
8.27 1.37e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.21 1.39e-02 GO:0044421 extracellular region part
29.54 1.73e-02 GO:0005577 fibrinogen complex
3.07 3.39e-02 GO:0044463 cell projection part
12.53 4.38e-02 GO:0034364 high-density lipoprotein particle

Gene overrepresentation in function category:

enrichment   p-value GO term description
8.75 7.83e-04 GO:0004867 serine-type endopeptidase inhibitor activity
25.06 3.13e-03 GO:0034185 apolipoprotein binding
4.00 5.43e-03 GO:0004857 enzyme inhibitor activity
9.62 7.99e-03 GO:0043498 cell surface binding
5.45 9.70e-03 GO:0004866 endopeptidase inhibitor activity
5.35 1.11e-02 GO:0030414 peptidase inhibitor activity
5.22 1.36e-02 GO:0061135 endopeptidase regulator activity
10.14 2.87e-02 GO:0005504 fatty acid binding