Motif ID: MTF1.p2

Z-value: 4.377


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MTF1chr1_-_38097811-0.155.7e-01Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_55217180 10.392 MT1E
metallothionein 1E
chr16_+_55217085 10.012 NM_175617
MT1E
metallothionein 1E
chr10_+_124211353 8.856 HTRA1
HtrA serine peptidase 1
chr3_-_187025501 8.096 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr16_+_55199978 7.960 NM_005953
MT2A
metallothionein 2A
chr16_+_55273879 7.407 NM_005952
MT1X
metallothionein 1X
chr16_+_55261226 7.287 NM_005951
MT1H
metallothionein 1H
chr16_+_55249355 6.477 NM_005949
MT1F
metallothionein 1F
chr3_-_187025438 6.243 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_+_124210980 6.038 NM_002775
HTRA1
HtrA serine peptidase 1
chr9_+_132309914 5.876 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr16_+_55230078 5.543 NM_005946
MT1A
metallothionein 1A
chr2_-_224612177 5.456 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr1_-_93199586 5.066 NM_001006605
FAM69A
family with sequence similarity 69, member A
chr1_-_9806611 4.595 CLSTN1
calsyntenin 1
chr16_-_55259405 4.447 NM_005950
MT1G
metallothionein 1G
chr16_-_51138306 4.198 NM_001080430
TOX3
TOX high mobility group box family member 3
chr12_+_6179736 3.999 NM_001769
CD9
CD9 molecule
chr20_-_10602139 3.983 JAG1
jagged 1
chr9_+_132310068 3.909 ASS1
argininosuccinate synthase 1
chr3_+_191714533 3.761 NM_001167928
NM_001167929
NM_001167930
NM_001167931
NM_002182
NM_134470
IL1RAP





interleukin 1 receptor accessory protein





chr2_-_220144427 3.702 OBSL1
obscurin-like 1
chr1_-_20685314 3.687 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr21_+_41461924 3.643 BACE2
beta-site APP-cleaving enzyme 2
chr2_+_173000590 3.625 ITGA6
integrin, alpha 6
chr8_+_136538739 3.583 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr8_-_121893468 3.579 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr13_+_97593411 3.561 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr11_-_11986704 3.425 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr19_-_18578577 3.417 CRLF1
cytokine receptor-like factor 1
chr13_+_97593469 3.400 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_-_168812132 3.381 NM_013233
STK39
serine threonine kinase 39
chr4_-_22126437 3.350 NM_145290
GPR125
G protein-coupled receptor 125
chr7_+_32963486 3.301 NM_007270
FKBP9
FK506 binding protein 9, 63 kDa
chr8_-_121893449 3.277 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr9_+_494661 3.238 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr13_-_105985313 3.228 NM_004093
EFNB2
ephrin-B2
chr2_+_235525355 3.141 NM_014521
SH3BP4
SH3-domain binding protein 4
chr13_+_26029799 3.113 NM_006646
WASF3
WAS protein family, member 3
chr3_-_101077605 3.059 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr11_-_114880275 3.023 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr8_+_26427378 3.013 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr11_+_69165018 2.996 NM_053056
CCND1
cyclin D1
chr2_-_160972606 2.994 RBMS1
RNA binding motif, single stranded interacting protein 1
chr19_-_18578631 2.961 NM_004750
CRLF1
cytokine receptor-like factor 1
chr9_-_94936319 2.908 NM_004148
NINJ1
ninjurin 1
chr1_-_223907283 2.907 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr21_+_17807167 2.880 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr11_+_69165119 2.813 CCND1
cyclin D1
chr6_+_142664490 2.793 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr9_-_93225780 2.777 NFIL3
nuclear factor, interleukin 3 regulated
chr8_+_56177567 2.724 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr3_-_135575925 2.714 NM_016201
AMOTL2
angiomotin like 2
chr18_-_20105814 2.696 OSBPL1A
oxysterol binding protein-like 1A
chr9_-_111122826 2.692 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr21_+_41461597 2.662 NM_012105
NM_138991
NM_138992
BACE2


beta-site APP-cleaving enzyme 2


chr9_+_123070234 2.639 GSN
gelsolin
chr2_+_20510312 2.569 NM_004040
RHOB
ras homolog gene family, member B
chr20_-_60375695 2.562 NM_005560
LAMA5
laminin, alpha 5
chr1_+_85819004 2.561 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr22_+_31527678 2.551 TIMP3
TIMP metallopeptidase inhibitor 3
chr12_+_51777684 2.520 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chrX_-_128485062 2.468 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr2_+_113119985 2.467 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr3_+_50167424 2.460 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_61522219 2.428 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr19_+_38377329 2.427 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr12_+_51777715 2.423 IGFBP6
insulin-like growth factor binding protein 6
chr15_-_68933481 2.319 NM_018357
NM_197958
LARP6

La ribonucleoprotein domain family, member 6

chr16_-_4106186 2.305 NM_001116
ADCY9
adenylate cyclase 9
chr8_+_97575317 2.269 SDC2
syndecan 2
chr6_+_17501589 2.257 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr22_+_31527744 2.249 TIMP3
TIMP metallopeptidase inhibitor 3
chr20_+_48240705 2.199 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr1_-_68071635 2.144 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr8_+_97575370 2.138 SDC2
syndecan 2
chr13_+_97593711 2.135 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_-_59022275 2.133 NM_002228
JUN
jun proto-oncogene
chr11_+_696103 2.131 NM_022772
EPS8L2
EPS8-like 2
chr16_-_63713382 2.124 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_+_7486836 2.123 DSP
desmoplakin
chr17_+_32924049 2.114 NM_007026
DUSP14
dual specificity phosphatase 14
chrX_-_128485121 2.114 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr9_-_111300350 2.108 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_19843261 2.107 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr10_-_125843092 2.107 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_-_20288108 2.100 NM_002997
SDC1
syndecan 1
chr8_+_97575244 2.079 SDC2
syndecan 2
chrX_-_102205736 2.076 BEX1
brain expressed, X-linked 1
chr12_-_105056577 2.075 NUAK1
NUAK family, SNF1-like kinase, 1
chr12_-_74711474 2.075 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_126088530 2.073 ITGB5
integrin, beta 5
chr9_-_109291130 2.071 KLF4
Kruppel-like factor 4 (gut)
chr8_+_97575196 2.070 SDC2
syndecan 2
chr2_-_101134146 2.068 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr14_+_20608179 2.047 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr14_-_104515738 2.042 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr2_-_224611568 2.023 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_-_35143900 1.983 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr8_-_48813236 1.949 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr12_-_123023312 1.946 CCDC92
coiled-coil domain containing 92
chr2_-_56004366 1.942 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr12_-_105165805 1.929 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr19_+_43830154 1.919 NM_004924
ACTN4
actinin, alpha 4
chr6_+_53767697 1.919 NM_018214
LRRC1
leucine rich repeat containing 1
chr3_+_134947788 1.915 TF
transferrin
chr19_-_18578467 1.914 CRLF1
cytokine receptor-like factor 1
chr17_-_72093476 1.910 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr11_-_2116775 1.903 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr18_+_54489798 1.903 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr17_-_72093739 1.892 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr11_+_69165159 1.877 CCND1
cyclin D1
chr2_+_9264327 1.876 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr11_+_35596310 1.868 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr14_+_73073570 1.859 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr18_+_54489763 1.858 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr18_+_54489658 1.848 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr13_+_26029879 1.845 WASF3
WAS protein family, member 3
chr2_+_9264360 1.843 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr20_+_48241334 1.828 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr3_+_134947573 1.825 NM_001063
TF
transferrin
chr5_-_122400312 1.811 NM_000943
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chrX_-_102205752 1.806 NM_018476
BEX1
brain expressed, X-linked 1
chr13_+_113587674 1.785 GAS6
growth arrest-specific 6
chr10_-_725522 1.785 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr3_-_51976428 1.784 NM_020418
NM_001174100
NM_033008
PCBP4


poly(rC) binding protein 4


chr7_-_94902149 1.784 NM_000305
NM_001018161
PON2

paraoxonase 2

chrX_-_51256166 1.780 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_+_43446937 1.774 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_38376980 1.773 LRP3
low density lipoprotein receptor-related protein 3
chr6_+_33697023 1.763 NM_002224
ITPR3
inositol 1,4,5-triphosphate receptor, type 3
chr2_-_20075929 1.751 NM_002381
MATN3
matrilin 3
chr16_+_55224034 1.749 NM_176870
MT1M
metallothionein 1M
chr2_-_235070431 1.740 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr11_+_10283171 1.729 NM_001124
ADM
adrenomedullin
chr20_-_55718351 1.725 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr13_-_44048601 1.722 NM_183422
TSC22D1
TSC22 domain family, member 1
chr3_+_37878647 1.701 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr19_+_43447078 1.696 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr11_-_11987198 1.695 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr8_+_26491317 1.674 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr17_-_5344898 1.654 NM_001162371
LOC728392
hypothetical protein LOC728392
chr7_-_80386258 1.643 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_+_136539290 1.642 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr6_-_3697244 1.633 NM_183373
C6orf145
chromosome 6 open reading frame 145
chr9_+_136358134 1.630 NM_002957
RXRA
retinoid X receptor, alpha
chr5_+_34692239 1.629 RAI14
retinoic acid induced 14
chrX_+_102518764 1.627 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr3_+_134947894 1.623 TF
transferrin
chr15_+_97010219 1.622 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr3_-_45162865 1.618 CDCP1
CUB domain containing protein 1
chr3_+_134947940 1.612 TF
transferrin
chr9_-_98841186 1.606 NM_001333
CTSL2
cathepsin L2
chr20_+_48240772 1.600 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr14_-_24588916 1.599 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr21_+_41461962 1.591 BACE2
beta-site APP-cleaving enzyme 2
chr2_+_238060602 1.581 NM_001042467
NM_024101
MLPH

melanophilin

chr15_-_61461127 1.576 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr14_-_68515727 1.576 ACTN1
actinin, alpha 1
chr8_-_67687980 1.574 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

hypothetical LOC645895
chr15_+_97009194 1.572 IGF1R
insulin-like growth factor 1 receptor
chr20_-_3102169 1.556 ProSAPiP1
ProSAPiP1 protein
chr15_-_61460967 1.548 CA12
carbonic anhydrase XII
chr14_-_34169047 1.544 NM_021249
NM_152233
SNX6

sorting nexin 6

chr17_+_1612031 1.538 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_77780177 1.532 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr12_-_88270375 1.529 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr11_-_11987115 1.528 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr19_+_43447262 1.526 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr8_+_22492586 1.519 PDLIM2
PDZ and LIM domain 2 (mystique)
chr3_-_45162847 1.518 CDCP1
CUB domain containing protein 1
chr5_-_79587588 1.515 NM_001174071
NM_001174072
NM_178276
SERINC5


serine incorporator 5


chr1_+_67168470 1.509 NM_001077701
NM_001077704
MIER1

mesoderm induction early response 1 homolog (Xenopus laevis)

chr3_-_45162901 1.500 NM_022842
NM_178181
CDCP1

CUB domain containing protein 1

chr1_-_43196911 1.496 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr9_-_112840064 1.493 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chrX_-_51256035 1.483 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr20_+_309675 1.479 TRIB3
tribbles homolog 3 (Drosophila)
chr13_-_76358433 1.472 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr6_+_123152044 1.471 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr12_-_88270128 1.464 DUSP6
dual specificity phosphatase 6
chr13_+_113546897 1.463 GAS6
growth arrest-specific 6
chr16_+_27232745 1.462 NM_000418
NM_001008699
IL4R

interleukin 4 receptor

chr5_+_65927895 1.462 NM_001164664
NM_198828
MAST4

microtubule associated serine/threonine kinase family member 4

chr17_+_1612056 1.461 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chrX_-_140098941 1.461 LDOC1
leucine zipper, down-regulated in cancer 1
chr10_-_99436889 1.461 NM_021732
AVPI1
arginine vasopressin-induced 1
chr9_-_109291575 1.454 KLF4
Kruppel-like factor 4 (gut)
chr5_-_72780107 1.450 NM_004472
FOXD1
forkhead box D1
chrX_-_140098959 1.449 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr14_+_73105618 1.443 ACOT2
acyl-CoA thioesterase 2
chr19_-_62043867 1.443 NM_001146326
NM_001146327
NM_015363
NM_001146184
NM_001146185
NM_001146187
NM_006210
ZIM2


PEG3



zinc finger, imprinted 2


paternally expressed 3



chr4_+_3737872 1.441 ADRA2C
adrenergic, alpha-2C-, receptor
chr11_+_101485946 1.434 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr17_+_1611983 1.430 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_+_202607554 1.424 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr2_-_254037 1.418 NM_001159597
NM_015677
SH3YL1

SH3 domain containing, Ysc84-like 1 (S. cerevisiae)

chr17_+_45858606 1.417 ACSF2
acyl-CoA synthetase family member 2
chr17_+_1612092 1.413 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_-_220144511 1.407 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.52 1.59e-16 GO:0007399 nervous system development
1.67 5.48e-16 GO:0022008 neurogenesis
1.69 7.74e-16 GO:0048699 generation of neurons
1.59 3.62e-12 GO:0048468 cell development
1.45 4.45e-12 GO:0009653 anatomical structure morphogenesis
1.69 4.63e-12 GO:0030182 neuron differentiation
1.38 6.38e-12 GO:0030154 cell differentiation
1.37 2.16e-11 GO:0048869 cellular developmental process
1.28 2.89e-11 GO:0048856 anatomical structure development
1.27 3.74e-11 GO:0007275 multicellular organismal development
1.82 5.48e-11 GO:0048812 neuron projection morphogenesis
1.72 7.30e-11 GO:0048666 neuron development
1.24 1.09e-10 GO:0032502 developmental process
1.76 2.49e-10 GO:0031175 neuron projection development
1.67 2.84e-10 GO:0030030 cell projection organization
1.75 4.45e-10 GO:0000904 cell morphogenesis involved in differentiation
1.75 4.45e-10 GO:0048858 cell projection morphogenesis
1.43 8.65e-10 GO:0009966 regulation of signal transduction
1.28 8.86e-10 GO:0048731 system development
1.73 1.11e-09 GO:0032990 cell part morphogenesis
1.62 1.30e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.80 1.51e-09 GO:0007409 axonogenesis
1.77 2.79e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.38 3.27e-09 GO:0023051 regulation of signaling
1.63 4.97e-09 GO:0032989 cellular component morphogenesis
1.69 5.95e-09 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.65 7.90e-09 GO:0000902 cell morphogenesis
1.18 7.75e-08 GO:0032501 multicellular organismal process
1.53 1.17e-07 GO:2000026 regulation of multicellular organismal development
1.81 1.40e-07 GO:0007411 axon guidance
1.85 1.77e-07 GO:0060284 regulation of cell development
1.20 6.07e-07 GO:0023052 signaling
1.87 8.79e-07 GO:0051960 regulation of nervous system development
1.44 3.12e-06 GO:0050793 regulation of developmental process
1.50 5.33e-06 GO:0019220 regulation of phosphate metabolic process
1.50 5.33e-06 GO:0051174 regulation of phosphorus metabolic process
2.25 5.60e-06 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.78 5.80e-06 GO:0022603 regulation of anatomical structure morphogenesis
1.51 7.54e-06 GO:0042325 regulation of phosphorylation
2.23 8.43e-06 GO:0022604 regulation of cell morphogenesis
1.87 9.75e-06 GO:0050767 regulation of neurogenesis
1.51 9.79e-06 GO:0045595 regulation of cell differentiation
1.49 5.64e-05 GO:0001932 regulation of protein phosphorylation
1.27 6.26e-05 GO:0048583 regulation of response to stimulus
1.19 9.67e-05 GO:0007165 signal transduction
1.46 1.19e-04 GO:0009719 response to endogenous stimulus
2.12 1.32e-04 GO:0030111 regulation of Wnt receptor signaling pathway
1.36 1.34e-04 GO:0010646 regulation of cell communication
1.87 2.81e-04 GO:0045664 regulation of neuron differentiation
1.39 2.92e-04 GO:0040011 locomotion
2.21 3.60e-04 GO:0031589 cell-substrate adhesion
1.55 4.66e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.46 5.27e-04 GO:0009725 response to hormone stimulus
2.06 5.69e-04 GO:0010975 regulation of neuron projection development
1.97 7.42e-04 GO:0034330 cell junction organization
2.27 8.60e-04 GO:0007160 cell-matrix adhesion
2.41 1.19e-03 GO:0050770 regulation of axonogenesis
1.30 1.65e-03 GO:0051239 regulation of multicellular organismal process
1.24 1.93e-03 GO:0007166 cell surface receptor linked signaling pathway
2.84 2.74e-03 GO:0030177 positive regulation of Wnt receptor signaling pathway
1.50 2.78e-03 GO:0051094 positive regulation of developmental process
1.49 3.52e-03 GO:0072358 cardiovascular system development
1.49 3.52e-03 GO:0072359 circulatory system development
1.10 3.64e-03 GO:0050794 regulation of cellular process
1.46 4.63e-03 GO:0006935 chemotaxis
1.46 4.63e-03 GO:0042330 taxis
1.62 5.21e-03 GO:0001944 vasculature development
1.21 5.29e-03 GO:0048523 negative regulation of cellular process
1.47 6.29e-03 GO:0007417 central nervous system development
1.20 6.71e-03 GO:0042221 response to chemical stimulus
1.86 8.12e-03 GO:0031344 regulation of cell projection organization
1.09 8.59e-03 GO:0065007 biological regulation
1.46 1.09e-02 GO:0043549 regulation of kinase activity
1.27 1.10e-02 GO:0035556 intracellular signal transduction
1.49 1.21e-02 GO:0008285 negative regulation of cell proliferation
1.49 1.21e-02 GO:0023057 negative regulation of signaling
1.50 1.40e-02 GO:0009968 negative regulation of signal transduction
1.56 1.42e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.45 1.48e-02 GO:0051338 regulation of transferase activity
1.54 1.53e-02 GO:0045597 positive regulation of cell differentiation
2.02 1.53e-02 GO:0035023 regulation of Rho protein signal transduction
1.48 1.62e-02 GO:0010648 negative regulation of cell communication
1.23 1.66e-02 GO:0006464 protein modification process
3.03 1.82e-02 GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
1.44 1.91e-02 GO:0019226 transmission of nerve impulse
1.44 1.91e-02 GO:0035637 multicellular organismal signaling
1.09 2.16e-02 GO:0050789 regulation of biological process
1.71 2.20e-02 GO:0014070 response to organic cyclic compound
1.65 2.27e-02 GO:0048011 nerve growth factor receptor signaling pathway
2.19 2.40e-02 GO:0048638 regulation of developmental growth
1.83 2.48e-02 GO:0016311 dephosphorylation
1.30 2.53e-02 GO:0009605 response to external stimulus
1.19 2.54e-02 GO:0048519 negative regulation of biological process
1.87 2.63e-02 GO:0034329 cell junction assembly
1.34 2.64e-02 GO:0031399 regulation of protein modification process
2.13 3.36e-02 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.56 3.36e-02 GO:0051270 regulation of cellular component movement
1.10 3.41e-02 GO:0050896 response to stimulus
1.59 3.47e-02 GO:0035295 tube development
1.43 3.63e-02 GO:0009967 positive regulation of signal transduction
1.30 3.82e-02 GO:0006793 phosphorus metabolic process
1.30 3.82e-02 GO:0006796 phosphate metabolic process
1.96 3.93e-02 GO:0010720 positive regulation of cell development
1.69 4.34e-02 GO:0010562 positive regulation of phosphorus metabolic process
1.69 4.34e-02 GO:0045937 positive regulation of phosphate metabolic process
1.44 4.48e-02 GO:0045859 regulation of protein kinase activity
1.33 4.69e-02 GO:0051128 regulation of cellular component organization
1.70 4.92e-02 GO:0042327 positive regulation of phosphorylation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 4.14e-09 GO:0016020 membrane
1.19 4.09e-07 GO:0071944 cell periphery
1.19 1.06e-06 GO:0005886 plasma membrane
1.09 3.64e-05 GO:0005737 cytoplasm
1.87 1.81e-04 GO:0070161 anchoring junction
1.21 4.86e-04 GO:0044459 plasma membrane part
1.87 7.64e-04 GO:0005912 adherens junction
1.59 1.15e-03 GO:0015629 actin cytoskeleton
1.76 1.56e-03 GO:0031252 cell leading edge
1.25 3.93e-03 GO:0005856 cytoskeleton
1.41 4.58e-03 GO:0030054 cell junction
2.66 8.35e-03 GO:0042641 actomyosin
1.92 1.07e-02 GO:0019898 extrinsic to membrane
1.10 1.51e-02 GO:0044425 membrane part
2.19 1.81e-02 GO:0032580 Golgi cisterna membrane
1.27 3.37e-02 GO:0005794 Golgi apparatus
1.39 3.97e-02 GO:0000139 Golgi membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 8.21e-06 GO:0005515 protein binding
1.54 1.42e-05 GO:0008092 cytoskeletal protein binding
1.53 1.04e-02 GO:0003779 actin binding
1.99 3.15e-02 GO:0019199 transmembrane receptor protein kinase activity
2.37 3.45e-02 GO:0046332 SMAD binding