Motif ID: NFKB1_REL_RELA.p2

Z-value: 4.001


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFKB1chr4_+_1036417620.853.4e-05Click!
RELchr2_+_609622060.656.2e-03Click!
RELAchr11_-_651867900.185.0e-01Click!


Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_4180494 8.072 NM_005755
EBI3
Epstein-Barr virus induced 3
chr19_-_6542012 7.085 CD70
CD70 molecule
chr5_-_149772469 6.386 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr11_+_101693403 6.099 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr22_+_21543671 5.644 IGLV4-3
immunoglobulin lambda variable 4-3
chr14_-_95250155 5.532 NM_001098725
NM_021966
TCL1A

T-cell leukemia/lymphoma 1A

chr6_+_14225932 5.244 CD83
CD83 molecule
chr6_+_32713160 5.066 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr2_-_162883062 4.793 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr14_-_34943574 4.728 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr6_+_116798791 4.687 NM_013352
DSE
dermatan sulfate epimerase
chr22_-_35875890 4.660 NM_000878
IL2RB
interleukin 2 receptor, beta
chr7_+_68702252 4.500 AUTS2
autism susceptibility candidate 2
chr21_+_25933459 4.382 NM_021219
JAM2
junctional adhesion molecule 2
chr5_-_149772563 4.349 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_-_32659958 4.240 HLA-DRB1
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 5
chr6_-_31432934 4.164 HLA-B
major histocompatibility complex, class I, B
chr12_+_6925997 4.085 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr16_+_84490267 3.982 NM_002163
IRF8
interferon regulatory factor 8
chr1_+_111571803 3.975 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr20_+_44180296 3.715 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr11_+_120828058 3.706 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr14_+_102313585 3.680 TRAF3
TNF receptor-associated factor 3
chr19_+_47073029 3.619 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr16_+_49333513 3.618 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr20_-_4743768 3.616 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr12_+_6926014 3.615 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_+_62804036 3.566 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_+_104145421 3.533 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr22_-_35970230 3.439 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_49333461 3.379 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr7_-_24763556 3.365 DFNA5
deafness, autosomal dominant 5
chr19_-_6542082 3.357 CD70
CD70 molecule
chr10_+_12431714 3.345 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr7_-_24763841 3.327 DFNA5
deafness, autosomal dominant 5
chr14_+_75058591 3.318 BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_75058518 3.317 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr22_-_35970133 3.284 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr15_+_83724743 3.222 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr19_-_7672978 3.111 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr6_-_31432954 2.941 NM_005514
HLA-B
major histocompatibility complex, class I, B
chr11_-_57092028 2.919 NM_198183
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr11_-_57092332 2.889 UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr19_-_11549441 2.838 ACP5
acid phosphatase 5, tartrate resistant
chr2_+_95055155 2.819 NM_002371
NM_022438
NM_022439
NM_022440
MAL



mal, T-cell differentiation protein



chr4_+_103641854 2.756 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr20_+_9443225 2.740 NM_012261
C20orf103
chromosome 20 open reading frame 103
chr4_+_103641762 2.727 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr7_-_24764082 2.687 NM_001127454
NM_004403
DFNA5

deafness, autosomal dominant 5

chr6_-_31432877 2.605 HLA-B
major histocompatibility complex, class I, B
chr17_+_69974116 2.599 NM_007261
CD300A
CD300a molecule
chr8_-_95343716 2.568 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr4_+_103641511 2.556 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr6_-_32919751 2.552 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr22_+_21552897 2.547 LOC100290481
immunoglobulin lambda light chain-like
chr1_-_181826633 2.539 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr13_-_45654327 2.460 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_3087026 2.422 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr14_+_102313566 2.367 NM_003300
NM_145725
NM_145726
TRAF3


TNF receptor-associated factor 3


chrX_+_12795111 2.366 NM_016562
TLR7
toll-like receptor 7
chr6_+_31647854 2.329 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr10_+_104144218 2.281 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr6_-_29635680 2.267 NM_006398
UBD
ubiquitin D
chr1_+_201541241 2.233 BTG2
BTG family, member 2
chr19_-_6542136 2.204 NM_001252
CD70
CD70 molecule
chr2_+_237143118 2.200 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr1_-_27834210 2.200 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr12_-_55790355 2.191 NM_001178079
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr21_+_25933637 2.179 JAM2
junctional adhesion molecule 2
chr5_-_142762947 2.171 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_-_93199586 2.164 NM_001006605
FAM69A
family with sequence similarity 69, member A
chr6_+_138230045 2.163 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr8_-_22606653 2.155 NM_004430
EGR3
early growth response 3
chr8_-_70909754 2.143 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr7_+_114349376 2.132 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr5_-_150441150 2.123 NM_006058
TNIP1
TNFAIP3 interacting protein 1
chr6_-_29635456 2.117 UBD
ubiquitin D
chr5_-_150440743 2.103 TNIP1
TNFAIP3 interacting protein 1
chr5_-_150440792 2.074 TNIP1
TNFAIP3 interacting protein 1
chr17_-_31231421 2.067 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chrX_+_78087484 2.063 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr16_+_49288550 2.060 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr8_+_54955962 2.052 NM_003702
RGS20
regulator of G-protein signaling 20
chr8_+_38877909 2.032 NM_021623
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr6_+_31648071 2.016 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr7_+_115952279 2.000 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr19_+_2427122 1.990 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr21_+_25933916 1.964 JAM2
junctional adhesion molecule 2
chr1_-_25129354 1.960 NM_004350
RUNX3
runt-related transcription factor 3
chr12_+_46785922 1.914 NM_001166686
PFKM
phosphofructokinase, muscle
chr1_-_180840016 1.914 NM_002928
RGS16
regulator of G-protein signaling 16
chr14_-_64040072 1.914 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr1_+_201541269 1.912 NM_006763
BTG2
BTG family, member 2
chr4_-_77163609 1.910 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr5_-_142763418 1.910 NM_000176
NM_001020825
NM_001024094
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr2_-_196744507 1.882 STK17B
serine/threonine kinase 17b
chr20_-_57015547 1.876 CTSZ
cathepsin Z
chr6_-_132764257 1.871 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr19_-_48976852 1.870 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr19_-_48977247 1.867 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr20_+_9443426 1.857 C20orf103
chromosome 20 open reading frame 103
chr5_-_171547844 1.842 STK10
serine/threonine kinase 10
chr11_-_3818759 1.841 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr19_+_50196526 1.838 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr3_+_123279439 1.837 NM_006889
CD86
CD86 molecule
chr3_-_58175437 1.834 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr14_-_105644300 1.823 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr1_-_183210155 1.823 FAM129A
family with sequence similarity 129, member A
chr19_+_55614006 1.822 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr20_+_44180355 1.822 CD40
CD40 molecule, TNF receptor superfamily member 5
chr5_-_171547925 1.821 NM_005990
STK10
serine/threonine kinase 10
chr21_+_25933938 1.809 JAM2
junctional adhesion molecule 2
chr4_+_142777172 1.804 NM_000585
NM_172174
IL15

interleukin 15

chr2_+_208103068 1.783 CREB1
cAMP responsive element binding protein 1
chr10_+_30762862 1.757 NM_005204
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr10_+_12431477 1.756 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr15_+_79376295 1.749 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr13_-_45654296 1.746 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_181826292 1.746 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr10_+_30763056 1.740 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr20_+_9443297 1.726 C20orf103
chromosome 20 open reading frame 103
chr3_+_53170254 1.707 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr2_+_208102860 1.699 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr5_-_171547700 1.696 STK10
serine/threonine kinase 10
chr17_+_69974361 1.673 CD300A
CD300a molecule
chr11_+_1846478 1.670 NM_001013253
LSP1
lymphocyte-specific protein 1
chr1_-_207891264 1.659 NM_001017402
LAMB3
laminin, beta 3
chr4_+_103641585 1.654 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr19_+_1018536 1.642 HMHA1
histocompatibility (minor) HA-1
chr1_-_181871447 1.638 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr17_-_7531456 1.634 NM_000546
NM_001126112
NM_001126113
NM_001126114
TP53



tumor protein p53



chr2_+_60962206 1.628 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_+_29799095 1.621 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr3_+_52207214 1.613 ALAS1
aminolevulinate, delta-, synthase 1
chr1_-_181871490 1.604 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr3_+_52207116 1.600 NM_199166
NM_000688
ALAS1

aminolevulinate, delta-, synthase 1

chr3_+_57236769 1.578 NM_012096
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr1_-_181871416 1.567 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr2_+_208102937 1.562 CREB1
cAMP responsive element binding protein 1
chrX_-_30505804 1.557 NM_025159
CXorf21
chromosome X open reading frame 21
chr7_+_115952325 1.546 CAV1
caveolin 1, caveolae protein, 22kDa
chr2_+_208103001 1.543 CREB1
cAMP responsive element binding protein 1
chr2_+_60962228 1.537 NM_002908
REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_+_29963485 1.524


chr11_-_3818713 1.514 RHOG
ras homolog gene family, member G (rho G)
chr11_+_58666749 1.507 NM_001142519
NM_001142520
NM_001142521
FAM111A


family with sequence similarity 111, member A


chr1_-_181871462 1.492 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr14_-_19090251 1.484 NM_001145442
POTEG
POTEM
POTE ankyrin domain family, member G
POTE ankyrin domain family, member M
chr17_-_59172852 1.467 STRADA
STE20-related kinase adaptor alpha
chr6_+_29963328 1.463 HLA-H
major histocompatibility complex, class I, H (pseudogene)
chr14_+_64948332 1.457 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr2_+_60962279 1.446 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr3_+_57236818 1.443 APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr10_+_90740364 1.418 FAS
Fas (TNF receptor superfamily, member 6)
chr2_+_233633279 1.406 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr4_-_185632610 1.401 NM_002199
IRF2
interferon regulatory factor 2
chr6_+_30018265 1.395 HLA-A
major histocompatibility complex, class I, A
chr7_+_7573074 1.388 NM_019005
MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr22_-_22252376 1.377 NM_020070
NM_152855
IGLL1

immunoglobulin lambda-like polypeptide 1

chr5_-_131854325 1.374 NM_002198
IRF1
interferon regulatory factor 1
chr14_-_105762742 1.370


chr8_-_95343696 1.349 GEM
GTP binding protein overexpressed in skeletal muscle
chr10_+_13182061 1.343 NM_001008211
NM_001008212
NM_001008213
NM_021980
OPTN



optineurin



chr1_-_181871508 1.334 NM_005717
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr1_-_207892420 1.329 NM_000228
LAMB3
laminin, beta 3
chr1_-_210939929 1.319 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr1_-_181871473 1.318 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr7_-_129379947 1.316 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr20_-_57015698 1.306 NM_001336
CTSZ
cathepsin Z
chr22_+_21094094 1.299


chr5_+_118632403 1.299 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr9_-_135334003 1.294 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr10_+_90740267 1.285 NM_000043
NM_152871
NM_152872
FAS


Fas (TNF receptor superfamily, member 6)


chr4_-_71751205 1.285 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr6_+_14225836 1.283 NM_001040280
NM_004233
CD83

CD83 molecule

chr14_+_64040979 1.274 NM_001123329
NM_014950
ZBTB1

zinc finger and BTB domain containing 1

chr6_+_36754433 1.271 NM_000389
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr5_+_110587546 1.268 NM_001744
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr6_-_33016561 1.258 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr17_-_16816113 1.248 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr4_-_71751070 1.245 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_196744546 1.241 NM_004226
STK17B
serine/threonine kinase 17b
chr6_+_30082331 1.237 HLA-J
major histocompatibility complex, class I, J (pseudogene)
chr7_+_7573159 1.232 MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr5_-_142763252 1.231 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_+_154389945 1.205 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr15_-_63871598 1.203 NM_001144823
NM_005848
DENND4A

DENN/MADD domain containing 4A

chr9_+_4480193 1.202 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr6_-_31432543 1.184 HLA-B
major histocompatibility complex, class I, B
chr2_+_218790364 1.178 NM_005731
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_235070431 1.158 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chrX_+_64804259 1.157 MSN
moesin
chrX_-_15782826 1.152


chr11_-_76800525 1.137 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr17_+_77783432 1.136 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chrX_-_15782842 1.129 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_64327197 1.123 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr14_-_105763152 1.108 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_+_233633348 1.103 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chrX_+_64804235 1.102 NM_002444
MSN
moesin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.84 1.13e-07 GO:0006955 immune response
2.45 2.08e-05 GO:0051249 regulation of lymphocyte activation
1.74 5.79e-05 GO:0002682 regulation of immune system process
1.53 6.39e-05 GO:0002376 immune system process
2.23 4.36e-04 GO:0002694 regulation of leukocyte activation
1.88 4.57e-04 GO:0002684 positive regulation of immune system process
2.47 4.89e-04 GO:0051251 positive regulation of lymphocyte activation
2.43 5.48e-04 GO:0045088 regulation of innate immune response
1.28 6.64e-04 GO:0007165 signal transduction
2.37 1.07e-03 GO:0002696 positive regulation of leukocyte activation
2.14 1.55e-03 GO:0050865 regulation of cell activation
2.33 1.74e-03 GO:0050867 positive regulation of cell activation
1.60 2.53e-03 GO:0006952 defense response
1.24 4.73e-03 GO:0023052 signaling
2.29 6.82e-03 GO:0050863 regulation of T cell activation
3.12 7.74e-03 GO:0034130 toll-like receptor 1 signaling pathway
3.12 7.74e-03 GO:0034134 toll-like receptor 2 signaling pathway
1.22 9.72e-03 GO:0051716 cellular response to stimulus
1.86 9.91e-03 GO:0045087 innate immune response
1.48 1.24e-02 GO:0043067 regulation of programmed cell death
1.48 1.43e-02 GO:0042981 regulation of apoptosis
1.74 1.51e-02 GO:0050776 regulation of immune response
1.48 1.52e-02 GO:0010941 regulation of cell death
5.14 1.61e-02 GO:0060603 mammary gland duct morphogenesis
2.98 1.65e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.15 1.71e-02 GO:0050794 regulation of cellular process
2.79 1.86e-02 GO:0002224 toll-like receptor signaling pathway
1.29 1.89e-02 GO:0048522 positive regulation of cellular process
2.69 2.33e-02 GO:0002758 innate immune response-activating signal transduction
2.66 2.86e-02 GO:0002218 activation of innate immune response
1.31 3.06e-02 GO:0048523 negative regulation of cellular process
1.27 3.15e-02 GO:0048518 positive regulation of biological process
2.33 3.52e-02 GO:0050870 positive regulation of T cell activation
3.03 3.66e-02 GO:0034138 toll-like receptor 3 signaling pathway
2.82 4.20e-02 GO:0008063 Toll signaling pathway
2.82 4.20e-02 GO:0034142 toll-like receptor 4 signaling pathway
2.66 4.31e-02 GO:0002221 pattern recognition receptor signaling pathway
2.99 4.69e-02 GO:0002756 MyD88-independent toll-like receptor signaling pathway
5.14 4.82e-02 GO:0060330 regulation of response to interferon-gamma
5.14 4.82e-02 GO:0060334 regulation of interferon-gamma-mediated signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
10.28 3.71e-03 GO:0033256 I-kappaB/NF-kappaB complex
1.28 2.01e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.34 4.27e-02 GO:0003823 antigen binding