Motif ID: NR6A1.p2

Z-value: 0.762


Transcription factors associated with NR6A1.p2:

Gene SymbolEntrez IDGene Name
NR6A1 2649 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR6A1chr9_-_126573349-0.533.3e-02Click!


Activity profile for motif NR6A1.p2.

activity profile for motif NR6A1.p2


Sorted Z-values histogram for motif NR6A1.p2

Sorted Z-values for motif NR6A1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR6A1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_224611568 2.526 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr17_-_45619038 2.336 COL1A1
collagen, type I, alpha 1
chr7_+_100037817 1.342 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr6_+_146906520 1.142 NM_006834
RAB32
RAB32, member RAS oncogene family
chr16_+_55199978 0.963 NM_005953
MT2A
metallothionein 2A
chr9_+_123083540 0.942 GSN
gelsolin
chr10_+_89409332 0.915 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr16_-_68317945 0.707 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr9_-_14304036 0.667 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr1_+_19796044 0.641 NM_001032363
C1orf15-NBL1
C1orf151
C1ORF15-NBL1 read-through transcript
chromosome 1 open reading frame 151
chr19_-_6671585 0.639 NM_000064
C3
complement component 3
chr2_-_162638875 0.632 DPP4
dipeptidyl-peptidase 4
chr2_-_162638746 0.543 DPP4
dipeptidyl-peptidase 4
chr9_-_14303899 0.520 NFIB
nuclear factor I/B
chr7_-_149669622 0.434 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr10_+_123744131 0.429 TACC2
transforming, acidic coiled-coil containing protein 2
chr6_+_129245978 0.390 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr9_+_35782405 0.368 NM_003995
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr9_-_14303509 0.357 NFIB
nuclear factor I/B
chr2_-_162638790 0.326 DPP4
dipeptidyl-peptidase 4
chr19_-_48382398 0.303 NM_001130014
NM_002781
PSG5

pregnancy specific beta-1-glycoprotein 5

chrX_+_102727068 0.293 NM_001006935
NM_001006937
NM_024863
TCEAL4


transcription elongation factor A (SII)-like 4


chr6_-_43592670 0.288 YIPF3
Yip1 domain family, member 3
chr19_-_14944729 0.244 NM_005071
SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chrX_-_21686079 0.244 NM_014332
SMPX
small muscle protein, X-linked
chr1_+_224064365 0.214 NM_001136018
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr8_-_125648576 0.214 MTSS1
metastasis suppressor 1
chr14_+_92188546 0.212 RIN3
Ras and Rab interactor 3
chr12_+_7039453 0.196


chr3_-_52287297 0.175 WDR82
WD repeat domain 82
chr19_+_10057972 0.173 C19orf66
chromosome 19 open reading frame 66
chr2_-_162638174 0.173 DPP4
dipeptidyl-peptidase 4
chr8_-_57521702 0.150 NM_001135690
PENK
proenkephalin
chr19_+_10058023 0.147 C19orf66
chromosome 19 open reading frame 66
chr19_-_48401532 0.143 NM_002780
NM_213633
PSG4

pregnancy specific beta-1-glycoprotein 4

chr1_-_151873191 0.124 NM_001024210
S100A13
S100 calcium binding protein A13
chr17_+_72958330 0.124 SEPT9
septin 9
chr11_+_64946820 0.117 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr2_-_31215074 0.107 NM_024572
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_+_224064427 0.106 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr7_+_45899080 0.105 IGFBP1
insulin-like growth factor binding protein 1
chr12_+_107797985 0.101 NM_001917
DAO
D-amino-acid oxidase
chr2_-_97775300 0.098 TMEM131
transmembrane protein 131
chr1_+_143920424 0.095 NM_203458
NOTCH2NL
notch 2 N-terminal like
chr8_-_53789544 0.084 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr1_+_234372454 0.082 NM_003272
GPR137B
G protein-coupled receptor 137B
chr6_-_133076873 0.080 NM_004666
VNN1
vanin 1
chr5_+_134237325 0.073 NM_024715
TXNDC15
thioredoxin domain containing 15
chr19_-_48133089 0.072 NM_002783
PSG7
pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
chr12_+_107480423 0.072 NM_014301
NM_213595
ISCU

iron-sulfur cluster scaffold homolog (E. coli)

chr12_-_6354650 0.068 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr7_+_28497272 0.067 CREB5
cAMP responsive element binding protein 5
chr8_-_93177057 0.066 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr6_-_43592481 0.065 YIPF3
Yip1 domain family, member 3
chr6_-_43592679 0.064 NM_015388
YIPF3
Yip1 domain family, member 3
chrX_-_104352005 0.064 NM_031274
TEX13A
testis expressed 13A
chr1_+_210805319 0.064 NM_001030287
ATF3
activating transcription factor 3
chr11_-_2113297 0.064 IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_134947894 0.064 TF
transferrin
chr17_-_24426752 0.060 NM_004740
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_+_19796119 0.058


chr3_+_46386636 0.055 NM_000579
NM_001100168
CCR5

chemokine (C-C motif) receptor 5

chr2_+_238265519 0.051 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr7_-_97439500 0.050 MGC72080
MGC72080 pseudogene
chr22_-_22252376 0.050 NM_020070
NM_152855
IGLL1

immunoglobulin lambda-like polypeptide 1

chr9_-_21207303 0.046 NM_002173
IFNA16
interferon, alpha 16
chr3_+_134947788 0.046 TF
transferrin
chr3_+_46594079 0.042 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr9_+_139101235 0.042 NM_016219
MAN1B1
mannosidase, alpha, class 1B, member 1
chr17_-_9870292 0.041 NM_001130831
GAS7
growth arrest-specific 7
chr3_+_134947573 0.040 NM_001063
TF
transferrin
chr4_+_41309668 0.040 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_+_26376560 0.036 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr10_+_51507891 0.035 NM_018232
FAM21B
family with sequence similarity 21, member B
chrX_+_48505097 0.033 NM_001080489
GLOD5
glyoxalase domain containing 5
chr12_-_56422120 0.032 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_+_47414028 0.028 NM_018232
FAM21B
family with sequence similarity 21, member B
chr16_+_31274030 0.027 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_+_238265617 0.024 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr6_-_116706828 0.023 TSPYL1
TSPY-like 1
chr14_-_46190690 0.023 NM_080746
RPL10L
ribosomal protein L10-like
chr12_+_2792047 0.022 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr1_+_78284176 0.022 NM_017655
GIPC2
GIPC PDZ domain containing family, member 2
chr18_+_11741470 0.021 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr9_-_21218132 0.017 NM_021268
IFNA17
interferon, alpha 17
chr12_-_10453409 0.017 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr9_-_134219950 0.017 SETX
senataxin
chr14_-_63264445 0.016 NM_030791
SGPP1
sphingosine-1-phosphate phosphatase 1
chr19_-_5797465 0.014 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr12_+_119632213 0.014 NM_001080533
UNC119B
unc-119 homolog B (C. elegans)
chr17_-_40339919 0.013 GFAP
glial fibrillary acidic protein
chr11_+_36274300 0.012 NM_001160167
PRR5L
proline rich 5 like
chr10_+_106004457 0.010 NM_001191002
NM_004832
GSTO1

glutathione S-transferase omega 1

chr16_+_55553262 0.009 NM_000078
CETP
cholesteryl ester transfer protein, plasma
chr22_+_30340152 0.008 SFI1
Sfi1 homolog, spindle assembly associated (yeast)
chr4_-_47709717 0.007 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr11_-_73397929 0.007 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr6_+_30964441 0.007 NM_013994
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_40009513 0.006 NM_022120
OXCT2
3-oxoacid CoA transferase 2
chr9_-_38059082 0.005 SHB
Src homology 2 domain containing adaptor protein B
chr16_+_31273969 0.004 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr14_-_75517844 0.003 NM_003239
TGFB3
transforming growth factor, beta 3
chr19_+_47079089 0.002 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr5_-_41249270 0.002 NM_000065
C6
complement component 6
chr12_-_61832856 0.001 NM_000706
AVPR1A
arginine vasopressin receptor 1A
chr15_+_75074793 0.001 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr22_+_49388427 0.001 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr21_-_36836767 0.001 NM_001146078
CLDN14
claudin 14
chr2_-_210798232 0.001 NM_001608
ACADL
acyl-CoA dehydrogenase, long chain
chr1_+_46151845 0.000 MAST2
microtubule associated serine/threonine kinase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
143.24 2.90e-02 GO:0001970 positive regulation of activation of membrane attack complex
143.24 2.90e-02 GO:0045917 positive regulation of complement activation
143.24 2.90e-02 GO:2000259 positive regulation of protein activation cascade
35.82 4.15e-02 GO:0010953 regulation of protein maturation by peptide bond cleavage
35.82 4.15e-02 GO:0070613 regulation of protein processing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.50 9.58e-04 GO:0005576 extracellular region

Nothing significant found in function category.