Motif ID: POU2F1..3.p2

Z-value: 5.296


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F2chr19_-_473283990.683.9e-03Click!
POU2F1chr1_+_1654565720.601.3e-02Click!
POU2F3chr11_+_1196161120.371.6e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_23754822 29.614 PRKCB
protein kinase C, beta
chr16_+_23754860 27.585 PRKCB
protein kinase C, beta
chr16_+_23754772 25.112 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr14_-_106084519 16.888 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_105997732 15.559 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_21116283 13.280


chr14_-_105762742 13.187


chr22_+_21065134 11.714 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21340757 11.690


chr22_+_21370394 11.533 IGL@
immunoglobulin lambda locus
chrX_-_48661226 11.287 NM_006875
PIM2
pim-2 oncogene
chr14_-_106184988 10.674 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_-_98021144 10.473 NM_001114094
NM_013314
BLNK

B-cell linker

chr14_-_105845570 10.452 IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_105589467 10.245 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr22_+_21065207 10.126 IGLJ3
immunoglobulin lambda joining 3
chr14_-_106064887 10.111 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr22_+_21407066 9.544


chr6_+_12825022 9.313 PHACTR1
phosphatase and actin regulator 1
chr22_+_21495273 8.841


chr6_-_27222556 8.672 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr14_-_105681377 8.591 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_26291936 8.583 NM_003523
HIST1H2BE
histone cluster 1, H2be
chr6_+_26232351 8.557 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr8_+_56954899 8.282 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr6_-_26232109 8.147 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr22_+_20899155 8.066


chr14_-_105763152 7.890 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_-_33016561 7.880 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr8_+_56954953 7.874 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr8_+_56954946 7.801 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_+_26266311 7.423 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr14_-_106270497 7.389 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr4_-_71751070 7.346 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_-_148126089 7.183 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr1_-_148050534 7.078 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr14_-_105623358 6.776 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_147665783 6.413 HIST2H2BF
histone cluster 2, H2bf
chr4_-_40212670 6.310 NM_019027
RBM47
RNA binding motif protein 47
chr6_+_26325124 6.076 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr6_-_26324850 6.007 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr6_+_26359805 5.950 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr10_-_64246129 5.939 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr14_-_105644300 5.937 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr22_+_20880112 5.914


chr22_+_21543671 5.795 IGLV4-3
immunoglobulin lambda variable 4-3
chr14_-_106241445 5.674 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr10_-_64246080 5.634 EGR2
early growth response 2
chr14_-_105796665 5.469 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr19_-_17377383 5.434 NM_004335
BST2
bone marrow stromal cell antigen 2
chr13_-_45640679 5.421 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_148080888 5.368 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr6_-_27968906 5.320 NM_003514
HIST1H2AM
histone cluster 1, H2am
chr22_+_21065202 5.272


chr5_-_88155360 5.013 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr1_-_153098811 4.998 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr12_-_8656705 4.977 NM_020661
AICDA
activation-induced cytidine deaminase
chr1_+_148089251 4.917 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr22_+_21384862 4.847 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr1_+_154386358 4.812 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_+_26381122 4.697 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr22_+_21042091 4.677 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr3_+_99733432 4.518 NM_005290
GPR15
G protein-coupled receptor 15
chr14_-_106137250 4.504


chr6_+_32515596 4.464 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr22_+_20880159 4.261 IGLV6-57
immunoglobulin lambda variable 6-57
chr3_+_188130967 4.261 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr22_+_21006814 4.090


chr8_+_26491507 4.075 DPYSL2
dihydropyrimidinase-like 2
chr1_+_165564904 3.847 NM_001198783
POU2F1
POU class 2 homeobox 1
chr1_+_165565006 3.800 POU2F1
POU class 2 homeobox 1
chr1_+_148125090 3.794 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr13_-_98757634 3.630 NM_004951
GPR183
G protein-coupled receptor 183
chr3_+_114733907 3.567 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr17_-_59363352 3.555 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr14_-_106170414 3.542 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr12_+_111829121 3.502 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr6_-_27208507 3.355 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chrX_-_80344096 3.341 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chr14_-_105817101 3.245


chr12_+_111829191 3.234 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr22_+_21094094 3.233


chr3_+_120799411 3.119 NM_015900
PLA1A
phospholipase A1 member A
chr6_+_27222839 3.109 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr4_-_74307637 3.063 ANKRD17
ankyrin repeat domain 17
chr6_+_34313007 3.030 HMGA1
high mobility group AT-hook 1
chr6_+_34312979 3.018 HMGA1
high mobility group AT-hook 1
chr14_-_106119742 2.987 IGLJ3
IGHG1
immunoglobulin lambda joining 3
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_108665665 2.985 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr14_-_105862080 2.882 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr8_+_86287161 2.817 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr17_-_16816113 2.803 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr6_+_34312667 2.797 HMGA1
high mobility group AT-hook 1
chr2_-_89400935 2.795 IGKC
immunoglobulin kappa constant
chrX_+_12903145 2.751 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr16_+_84202515 2.732 NM_001134473
KIAA0182
KIAA0182
chr6_+_34312906 2.715 HMGA1
high mobility group AT-hook 1
chr6_+_37245860 2.714 NM_002648
PIM1
pim-1 oncogene
chr6_+_27208763 2.674 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr1_-_226712140 2.639 NM_033445
HIST3H2A
histone cluster 3, H2a
chr20_-_48980858 2.630 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr7_+_50318801 2.616 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr6_+_34312641 2.509 HMGA1
high mobility group AT-hook 1
chr6_-_26151863 2.458 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr10_+_97505398 2.409 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr1_+_226712430 2.348 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr6_-_143307976 2.330 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chrX_+_123062143 2.311 STAG2
stromal antigen 2
chr15_-_64436045 2.310 NM_017858
TIPIN
TIMELESS interacting protein
chr2_-_172458970 2.299 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr14_-_105796268 2.287 ZCWPW2
IGHV3-23
IGKV3-20
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
chr14_-_106202262 2.238 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr15_+_81906983 2.208 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr2_-_236837726 2.205 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr6_-_27890496 2.203 NM_021066
HIST1H2AJ
histone cluster 1, H2aj
chr7_-_112514990 2.192 GPR85
G protein-coupled receptor 85
chr19_-_60611136 2.180 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr14_-_105712630 2.174 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_112515035 2.134 GPR85
G protein-coupled receptor 85
chr14_-_105542441 2.133 IGLJ3
IGHA1
IGHG1
IGHM
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chrX_+_37524190 2.128 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr6_+_34312633 2.116 HMGA1
high mobility group AT-hook 1
chr5_+_68702617 2.099 NM_133340
NM_133341
RAD17

RAD17 homolog (S. pombe)

chr9_+_99303282 2.064 NM_001166116
TMOD1
tropomodulin 1
chr22_+_20715340 2.016


chr4_-_91979113 2.003 NM_183049
TMSL3
thymosin-like 3
chr1_+_202000906 1.979 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chrX_+_80343958 1.974 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr14_-_105657378 1.863 IGHV4-31
immunoglobulin heavy variable 4-31
chr2_-_89294466 1.853 IGKC
immunoglobulin kappa constant
chr7_-_112515068 1.845 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr6_+_27969181 1.789 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr8_-_33490094 1.782 NM_025115
NM_001102401
C8orf41

chromosome 8 open reading frame 41

chr2_-_2313894 1.773 NM_015025
MYT1L
myelin transcription factor 1-like
chr22_-_22426551 1.751 NM_013378
VPREB3
pre-B lymphocyte 3
chr17_-_26665213 1.748 EVI2B
ecotropic viral integration site 2B
chrX_+_37524250 1.717 CYBB
cytochrome b-245, beta polypeptide
chr2_-_175170674 1.716 WIPF1
WAS/WASL interacting protein family, member 1
chr16_+_28850760 1.715 NM_001178098
NM_001770
CD19

CD19 molecule

chr19_-_18253259 1.685


chr12_+_60940404 1.680 NM_006313
USP15
ubiquitin specific peptidase 15
chr17_-_7773477 1.671 NM_004732
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr16_-_73366200 1.671 NM_024306
FA2H
fatty acid 2-hydroxylase
chr6_+_27323458 1.670 NM_005865
PRSS16
protease, serine, 16 (thymus)
chr2_+_96790298 1.649 NM_020184
CNNM4
cyclin M4
chr3_-_122862391 1.617 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr6_+_27890772 1.612 NM_003521
HIST1H2BM
histone cluster 1, H2bm
chr8_+_19840861 1.593 NM_000237
LPL
lipoprotein lipase
chr5_+_68703036 1.578 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr15_-_56145140 1.577 NM_003888
NM_170696
ALDH1A2

aldehyde dehydrogenase 1 family, member A2

chr12_-_31370387 1.574 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr12_-_31370305 1.572 FAM60A
family with sequence similarity 60, member A
chr12_-_31370351 1.568 FAM60A
family with sequence similarity 60, member A
chrX_+_80344215 1.552 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr14_-_105792495 1.537


chr8_+_19841010 1.533 LPL
lipoprotein lipase
chr5_-_66528330 1.521 NM_005582
CD180
CD180 molecule
chr6_+_34312625 1.496 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr9_-_94226380 1.491 NM_005014
OMD
osteomodulin
chr1_-_42738535 1.475 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr8_+_19841120 1.456 LPL
lipoprotein lipase
chr11_-_11331411 1.448 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr16_-_73365975 1.439 FA2H
fatty acid 2-hydroxylase
chrX_+_80344253 1.435 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr19_+_757401 1.361 PTBP1
polypyrimidine tract binding protein 1
chr12_-_120270035 1.334 ANAPC5
anaphase promoting complex subunit 5
chr6_-_168222645 1.312 NM_024919
FRMD1
FERM domain containing 1
chr15_-_81037554 1.282 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr11_+_22646229 1.268 NM_177553
GAS2
growth arrest-specific 2
chr4_-_71751205 1.250 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr13_-_50925134 1.250 INTS6
integrator complex subunit 6
chr2_-_152393128 1.215 ARL5A
ADP-ribosylation factor-like 5A
chr6_+_27883877 1.207 NM_003509
HIST1H2AI
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H3f
chr20_+_34019942 1.175 NM_080834
C20orf152
chromosome 20 open reading frame 152
chr1_-_85946676 1.174 NM_001170670
NM_017953
ZNHIT6

zinc finger, HIT-type containing 6

chr4_-_77163609 1.172 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr20_+_62266270 1.164 NM_004535
MYT1
myelin transcription factor 1
chr14_-_106289751 1.159 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr6_+_34312554 1.150 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr15_+_89279502 1.116 UNC45A
unc-45 homolog A (C. elegans)
chr17_-_38529638 1.113 NM_007298
BRCA1
breast cancer 1, early onset
chr2_-_238861830 1.102 NM_022817
PER2
period homolog 2 (Drosophila)
chr19_-_19142090 1.102 NM_001145785
MEF2B
myocyte enhancer factor 2B
chr11_+_63829616 1.096 NM_004451
ESRRA
estrogen-related receptor alpha
chr4_-_176970407 1.089 GPM6A
glycoprotein M6A
chr1_+_221168388 1.076 NM_032890
DISP1
dispatched homolog 1 (Drosophila)
chr1_-_163680941 1.073 NM_006917
RXRG
retinoid X receptor, gamma
chr2_-_152393209 1.069 NM_001037174
NM_012097
NM_177985
ARL5A


ADP-ribosylation factor-like 5A


chr19_-_19142053 1.043 MEF2B
myocyte enhancer factor 2B
chr14_-_105524207 1.041 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_-_122862447 1.033 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_-_54860678 1.029 IRF3
interferon regulatory factor 3
chr8_+_7789608 1.014 NM_004942
DEFB4A
defensin, beta 4A
chr19_+_45996881 1.013 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr7_-_100021689 1.010 NM_002319
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_-_43763488 1.009 MRPS18A
mitochondrial ribosomal protein S18A
chr6_-_43763517 0.987 NM_001193343
NM_018135
MRPS18A

mitochondrial ribosomal protein S18A

chr15_+_47249700 0.979 NM_002044
GALK2
galactokinase 2
chr9_+_19280748 0.965 NM_017925
DENND4C
DENN/MADD domain containing 4C
chr1_-_68735314 0.941 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
9.31 3.33e-14 GO:0071824 protein-DNA complex subunit organization
10.43 5.20e-14 GO:0006334 nucleosome assembly
9.71 5.72e-14 GO:0034728 nucleosome organization
10.18 9.23e-14 GO:0031497 chromatin assembly
9.50 9.67e-14 GO:0065004 protein-DNA complex assembly
7.68 3.68e-12 GO:0006333 chromatin assembly or disassembly
7.97 2.41e-11 GO:0006323 DNA packaging
7.01 1.12e-10 GO:0071103 DNA conformation change
3.47 1.63e-07 GO:0006325 chromatin organization
3.20 7.98e-07 GO:0034621 cellular macromolecular complex subunit organization
3.58 1.99e-06 GO:0034622 cellular macromolecular complex assembly
2.88 4.82e-06 GO:0051276 chromosome organization
2.55 9.02e-06 GO:0006955 immune response
1.99 5.21e-04 GO:0002376 immune system process
2.24 7.60e-04 GO:0043933 macromolecular complex subunit organization
2.37 1.09e-03 GO:0065003 macromolecular complex assembly
1.72 1.97e-02 GO:0006996 organelle organization
5.32 4.61e-02 GO:0042113 B cell activation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
15.65 3.63e-19 GO:0000786 nucleosome
5.91 4.22e-14 GO:0000785 chromatin
9.71 4.93e-14 GO:0032993 protein-DNA complex
3.28 2.53e-07 GO:0044427 chromosomal part
2.98 5.89e-07 GO:0005694 chromosome
1.46 2.12e-02 GO:0043228 non-membrane-bounded organelle
1.46 2.12e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.26 3.82e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
10.56 8.10e-07 GO:0003823 antigen binding
1.64 1.16e-03 GO:0003677 DNA binding
1.46 5.81e-03 GO:0003676 nucleic acid binding