Motif ID: TEAD1.p2

Z-value: 5.708


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_126524270.924.6e-07Click!
TEAD3chr6_-_355726940.611.3e-02Click!
TEAD4chr12_+_29392500.391.4e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132314004 26.304 NM_001901
CTGF
connective tissue growth factor
chr5_-_39460687 25.548 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr3_-_135575925 14.807 NM_016201
AMOTL2
angiomotin like 2
chr5_-_39460787 13.858 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_37660568 13.512 NM_003246
THBS1
thrombospondin 1
chr1_+_85819004 12.503 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr6_-_128883125 12.372 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr2_-_160972606 12.278 RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_-_90702490 11.816 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_6298284 11.570 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr10_-_17699309 11.284 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_-_39461054 11.220 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_61121806 10.678 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr7_+_134114701 10.306 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr2_-_189752575 10.132 NM_000393
COL5A2
collagen, type V, alpha 2
chr15_+_61122139 9.944 TPM1
tropomyosin 1 (alpha)
chr11_+_113671744 9.850 NM_006169
NNMT
nicotinamide N-methyltransferase
chr4_+_184257337 9.715 NM_024949
WWC2
WW and C2 domain containing 2
chr5_-_151046680 9.179 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_-_125843092 8.955 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr20_+_34603290 8.616 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr11_-_2907169 8.456 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr8_-_42184194 8.432 PLAT
plasminogen activator, tissue
chr3_-_150569574 8.228 TM4SF1
transmembrane 4 L six family member 1
chr7_+_134114957 8.174 CALD1
caldesmon 1
chr20_+_34603311 8.039 MYL9
myosin, light chain 9, regulatory
chr8_-_42184350 7.963 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chrX_-_10548458 7.874 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr8_+_1759502 7.739 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr7_+_115952279 7.715 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr8_-_13018123 7.370 NM_001164271
DLC1
deleted in liver cancer 1
chr1_-_1283770 7.257 NM_032348
MXRA8
matrix-remodelling associated 8
chr12_-_13044467 7.207 NM_015987
HEBP1
heme binding protein 1
chr1_+_114323552 7.156 NM_020190
OLFML3
olfactomedin-like 3
chr16_-_62573 7.142 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr12_-_13044314 7.039 HEBP1
heme binding protein 1
chr6_-_134538762 6.871 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_8789457 6.820 NM_139157
ST5
suppression of tumorigenicity 5
chr1_-_199613427 6.817 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr10_+_123862430 6.605 TACC2
transforming, acidic coiled-coil containing protein 2
chr6_-_134538526 6.601 SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_158439868 6.561 NM_001105
ACVR1
activin A receptor, type I
chr1_-_199613406 6.469 TNNT2
troponin T type 2 (cardiac)
chr5_-_151046638 6.289 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr18_+_8707368 6.249 NM_015210
KIAA0802
KIAA0802
chr4_-_186970366 6.242 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr5_+_34723420 6.060 NM_001145523
RAI14
retinoic acid induced 14
chr17_-_37828643 6.053 NM_012232
PTRF
polymerase I and transcript release factor
chr8_+_70541412 5.989 NM_001128204
NM_015170
SULF1

sulfatase 1

chr10_+_102782151 5.850 SFXN3
sideroflexin 3
chr10_-_33287184 5.606 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr3_-_115825742 5.572 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_115952325 5.459 CAV1
caveolin 1, caveolae protein, 22kDa
chr15_-_46725087 5.457 NM_000138
FBN1
fibrillin 1
chr2_-_217248967 5.313 IGFBP5
insulin-like growth factor binding protein 5
chr11_-_8788765 5.199 NM_213618
ST5
suppression of tumorigenicity 5
chr3_-_52463070 5.103 NM_003280
TNNC1
troponin C type 1 (slow)
chr10_-_99436889 5.032 NM_021732
AVPI1
arginine vasopressin-induced 1
chr11_-_2127368 5.017 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr13_+_109936080 4.969 COL4A2
collagen, type IV, alpha 2
chr12_-_7136147 4.700 NM_001733
C1R
complement component 1, r subcomponent
chr12_-_8706746 4.677 MFAP5
microfibrillar associated protein 5
chr7_+_115952074 4.509 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chrX_-_6156655 4.427 NM_181332
NLGN4X
neuroligin 4, X-linked
chr12_-_7136189 4.409 C1R
complement component 1, r subcomponent
chr1_+_181422016 4.269 LAMC2
laminin, gamma 2
chr12_-_8706637 4.151 NM_003480
MFAP5
microfibrillar associated protein 5
chr6_+_83130220 4.002 TPBG
trophoblast glycoprotein
chr10_+_102782156 3.929 SFXN3
sideroflexin 3
chr1_-_207892420 3.809 NM_000228
LAMB3
laminin, beta 3
chr3_+_148609841 3.763 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr17_-_15495534 3.755 TRIM16
tripartite motif containing 16
chr2_-_192420168 3.747 NM_004657
SDPR
serum deprivation response
chr12_-_53099269 3.727 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr15_-_58477407 3.721 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr2_-_20075889 3.659 MATN3
matrilin 3
chr1_-_207892296 3.603 NM_001127641
LAMB3
laminin, beta 3
chr4_-_186815116 3.568 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr1_+_26480134 3.552 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr9_+_111927601 3.533 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr7_+_134114912 3.453 CALD1
caldesmon 1
chr11_-_47427263 3.442 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr12_-_8706533 3.441 MFAP5
microfibrillar associated protein 5
chr11_+_57123927 3.378 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr12_-_53099277 3.348 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr21_+_46369606 3.332 COL6A2
collagen, type VI, alpha 2
chr9_+_19039424 3.312 RRAGA
Ras-related GTP binding A
chr6_+_83129641 3.278 NM_006670
TPBG
trophoblast glycoprotein
chr1_-_212791597 3.276 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_-_201411533 3.238 NM_004997
MYBPH
myosin binding protein H
chr15_+_30721161 3.235 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr1_-_16355013 3.223 NM_004431
EPHA2
EPH receptor A2
chr2_-_192419896 3.203 SDPR
serum deprivation response
chr12_-_53099203 3.181 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_+_66580884 3.071 RHOD
ras homolog gene family, member D
chr11_+_66580861 3.046 NM_014578
RHOD
ras homolog gene family, member D
chr12_+_77782648 2.899 SYT1
synaptotagmin I
chr8_+_56177567 2.886 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr12_-_119172339 2.858 NM_025157
PXN
paxillin
chr19_-_49523747 2.846 ZFP112
zinc finger protein 112 homolog (mouse)
chr6_+_123152044 2.833 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr5_-_83052606 2.816 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr12_+_47498778 2.796 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chrX_-_152794592 2.776 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chrX_-_10761729 2.761 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr1_-_212791467 2.761 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr19_-_14467939 2.709 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
GIPC1





GIPC PDZ domain containing family, member 1





chr21_-_26345294 2.639


chr3_-_129023850 2.625 NM_007283
MGLL
monoglyceride lipase
chr12_+_77782579 2.552 NM_005639
SYT1
synaptotagmin I
chr10_+_123738678 2.552 NM_206861
NM_206862
TACC2

transforming, acidic coiled-coil containing protein 2

chr19_-_14467890 2.502 GIPC1
GIPC PDZ domain containing family, member 1
chr12_+_26239755 2.461 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr12_+_77782719 2.444 SYT1
synaptotagmin I
chr5_-_175775966 2.426 CLTB
clathrin, light chain B
chr19_+_55918405 2.413 NM_002975
CLEC11A
C-type lectin domain family 11, member A
chr16_+_55156461 2.406 NM_032935
MT4
metallothionein 4
chr15_+_94670160 2.388 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_-_54387934 2.382 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr19_+_55918450 2.337 CLEC11A
C-type lectin domain family 11, member A
chr6_+_134251957 2.334 TCF21
transcription factor 21
chr21_+_46369617 2.328 COL6A2
collagen, type VI, alpha 2
chr6_+_134251940 2.309 NM_198392
NM_003206
TCF21

transcription factor 21

chr11_+_19328846 2.304 NM_001111018
NAV2
neuron navigator 2
chr11_-_14336606 2.297 NM_001177315
NM_001102669
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chr1_+_181380837 2.295 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr12_+_51728999 2.246 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_+_77781903 2.221 NM_001135805
SYT1
synaptotagmin I
chr1_-_17179694 2.205 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr12_-_54387732 2.200 ITGA7
integrin, alpha 7
chr6_+_158653679 2.199 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr17_-_3518628 2.190 TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr1_-_199704773 2.190 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr9_+_34980715 1.989 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr6_+_144040751 1.951 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr19_+_50041424 1.950 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_+_216585298 1.941 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr5_+_140848905 1.936 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr11_+_2881080 1.910 SLC22A18
solute carrier family 22, member 18
chr8_-_116750427 1.866 TRPS1
trichorhinophalangeal syndrome I
chr17_-_3518568 1.852 TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr4_+_169789327 1.794 NM_001166109
PALLD
palladin, cytoskeletal associated protein
chr22_+_43451600 1.794 PRR5
proline rich 5 (renal)
chr14_-_22974707 1.763 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr22_+_43451351 1.755 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chrX_+_107569671 1.752 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr5_-_16989371 1.721 NM_012334
MYO10
myosin X
chr12_-_78608873 1.662 NM_002583
PAWR
PRKC, apoptosis, WT1, regulator
chr12_-_45506001 1.649 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr4_-_187114863 1.627 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr12_+_27568311 1.609 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chrX_+_48253007 1.608 NM_203474
NM_203475
PORCN

porcupine homolog (Drosophila)

chr5_-_55326358 1.607 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr18_+_3237527 1.595 NM_006471
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr16_-_46052596 1.592 ITFG1
integrin alpha FG-GAP repeat containing 1
chr18_+_3237774 1.582 MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr9_-_16717887 1.570 BNC2
basonuclin 2
chr5_+_140730014 1.565 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr16_-_21344158 1.560 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr8_+_70567634 1.559 SULF1
sulfatase 1
chr5_-_176857158 1.527 PDLIM7
PDZ and LIM domain 7 (enigma)
chr17_+_71229151 1.511 ITGB4
integrin, beta 4
chr1_-_149047329 1.502 NM_000396
CTSK
cathepsin K
chr5_+_34720368 1.485 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr16_+_22432344 1.450 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr15_+_30797466 1.443 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr10_-_33287137 1.433 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr17_-_38421363 1.432 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr14_+_75114692 1.430 NM_017791
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr11_+_7463175 1.420 NM_198474
OLFML1
olfactomedin-like 1
chr12_-_105057940 1.418 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr16_+_15435825 1.411 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr5_+_76150637 1.374 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr7_-_80386258 1.361 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr18_+_3237825 1.332 MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr6_-_3102690 1.323 NM_001069
TUBB2A
tubulin, beta 2A
chr6_+_131508153 1.282 NM_016377
AKAP7
A kinase (PRKA) anchor protein 7
chr3_+_160269734 1.278 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr12_+_118100977 1.269 NM_014365
HSPB8
heat shock 22kDa protein 8
chr6_+_30958672 1.264 DDR1
discoidin domain receptor tyrosine kinase 1
chr4_-_186814852 1.262 SORBS2
sorbin and SH3 domain containing 2
chr19_-_56147971 1.256 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr1_+_86942810 1.247 NM_016009
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr11_-_6600385 1.229 DCHS1
dachsous 1 (Drosophila)
chr18_+_3252110 1.210 NM_033546
MYL12B
myosin, light chain 12B, regulatory
chr1_-_116112921 1.206 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr2_+_151922350 1.202 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr3_-_150858274 1.198 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr4_+_148758014 1.189 TMEM184C
transmembrane protein 184C
chr5_+_179165957 1.184 NM_001142298
SQSTM1
sequestosome 1
chr1_-_148175383 1.181 NM_001145862
MTMR11
myotubularin related protein 11
chr1_+_144236346 1.178 NM_003637
ITGA10
integrin, alpha 10
chr3_+_138020550 1.176 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr18_+_3237815 1.165 MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_+_181258952 1.162 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr9_+_123123364 1.140 GSN
gelsolin
chr7_+_142789476 1.137 ZYX
zyxin
chr11_-_65082705 1.122 LTBP3
latent transforming growth factor beta binding protein 3
chr3_+_171422908 1.108 NM_002740
PRKCI
protein kinase C, iota
chrX_+_48252290 1.099 NM_022825
NM_203473
PORCN

porcupine homolog (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.99 1.44e-04 GO:0048468 cell development
1.73 2.45e-04 GO:0009653 anatomical structure morphogenesis
1.51 1.39e-03 GO:0042221 response to chemical stimulus
2.11 1.67e-03 GO:0032989 cellular component morphogenesis
1.42 2.21e-03 GO:0048856 anatomical structure development
1.97 3.64e-03 GO:0007155 cell adhesion
1.97 3.64e-03 GO:0022610 biological adhesion
2.67 4.23e-03 GO:0061061 muscle structure development
2.05 4.89e-03 GO:0030030 cell projection organization
1.35 7.38e-03 GO:0032502 developmental process
2.97 9.38e-03 GO:0007517 muscle organ development
3.55 1.01e-02 GO:0014706 striated muscle tissue development
2.13 1.49e-02 GO:0048858 cell projection morphogenesis
1.41 1.68e-02 GO:0048731 system development
2.11 1.88e-02 GO:0032990 cell part morphogenesis
2.18 1.99e-02 GO:0048812 neuron projection morphogenesis
2.45 2.26e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.10 2.52e-02 GO:0031175 neuron projection development
2.00 2.53e-02 GO:0000902 cell morphogenesis
2.06 2.59e-02 GO:0006935 chemotaxis
2.06 2.59e-02 GO:0042330 taxis
2.35 2.60e-02 GO:0007411 axon guidance
3.24 3.47e-02 GO:0060537 muscle tissue development
2.16 4.03e-02 GO:0007409 axonogenesis
6.32 4.58e-02 GO:0007044 cell-substrate junction assembly

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.70 4.37e-06 GO:0005576 extracellular region
1.92 1.62e-05 GO:0044421 extracellular region part
2.74 6.98e-05 GO:0015629 actin cytoskeleton
5.33 1.73e-04 GO:0016459 myosin complex
3.84 4.96e-04 GO:0044420 extracellular matrix part
3.31 1.24e-03 GO:0043235 receptor complex
2.31 3.82e-03 GO:0031012 extracellular matrix
1.82 3.95e-03 GO:0005615 extracellular space
1.30 1.36e-02 GO:0071944 cell periphery
4.20 1.43e-02 GO:0005604 basement membrane
14.76 1.69e-02 GO:0001527 microfibril
2.26 3.73e-02 GO:0005578 proteinaceous extracellular matrix
1.29 4.02e-02 GO:0005886 plasma membrane
5.74 4.41e-02 GO:0001725 stress fiber
1.39 4.56e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.96 3.31e-03 GO:0005509 calcium ion binding
2.28 1.75e-02 GO:0003779 actin binding
3.91 1.90e-02 GO:0005201 extracellular matrix structural constituent
6.74 1.96e-02 GO:0050840 extracellular matrix binding
2.92 2.85e-02 GO:0005539 glycosaminoglycan binding
4.86 2.88e-02 GO:0008307 structural constituent of muscle
1.17 3.43e-02 GO:0005515 protein binding
22.13 3.67e-02 GO:0004924 oncostatin-M receptor activity