Motif ID: AAUGCCC

Z-value: 0.545


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365a-3p MIMAT0000710
hsa-miR-365b-3p MIMAT0022834



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_123603137 0.434 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
 MYLK



myosin light chain kinase



chr6_-_134639180 0.432 ENST00000367858.5
 SGK1
serum/glucocorticoid regulated kinase 1
chr15_+_52121822 0.387 ENST00000558455.1
ENST00000308580.7
 TMOD3

tropomodulin 3 (ubiquitous)

chr12_+_72666407 0.370 ENST00000261180.4
 TRHDE
thyrotropin-releasing hormone degrading enzyme
chr7_-_83824169 0.316 ENST00000265362.4
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr21_-_28217721 0.314 ENST00000284984.3
 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr10_-_62149433 0.277 ENST00000280772.2
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr9_-_117880477 0.265 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
 TNC





tenascin C





chr2_+_46926048 0.254 ENST00000306503.5
 SOCS5
suppressor of cytokine signaling 5
chr5_-_43313574 0.240 ENST00000325110.6
ENST00000433297.2
 HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr11_+_34642656 0.233 ENST00000257831.3
ENST00000450654.2
 EHF

ets homologous factor

chr1_-_153588334 0.215 ENST00000476873.1
 S100A14
S100 calcium binding protein A14
chr8_+_54764346 0.207 ENST00000297313.3
ENST00000344277.6
 RGS20

regulator of G-protein signaling 20

chr9_-_14314066 0.199 ENST00000397575.3
 NFIB
nuclear factor I/B
chr15_+_96873921 0.194 ENST00000394166.3
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_+_133861790 0.189 ENST00000395003.1
 PHF15
jade family PHD finger 2
chr2_-_183903133 0.188 ENST00000361354.4
 NCKAP1
NCK-associated protein 1
chr4_-_11431389 0.186 ENST00000002596.5
 HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr10_+_1095416 0.185 ENST00000358220.1
 WDR37
WD repeat domain 37
chr4_-_149365827 0.163 ENST00000344721.4
 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr1_+_2160134 0.154 ENST00000378536.4
 SKI
v-ski avian sarcoma viral oncogene homolog
chr1_-_23857698 0.152 ENST00000361729.2
 E2F2
E2F transcription factor 2
chr3_-_33481835 0.144 ENST00000283629.3
 UBP1
upstream binding protein 1 (LBP-1a)
chr2_-_200322723 0.140 ENST00000417098.1
 SATB2
SATB homeobox 2
chr7_-_150652924 0.137 ENST00000330883.4
 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr10_-_105615164 0.122 ENST00000355946.2
ENST00000369774.4
 SH3PXD2A

SH3 and PX domains 2A

chr22_+_32340481 0.119 ENST00000397492.1
 YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr16_-_79634595 0.115 ENST00000326043.4
ENST00000393350.1
 MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

chr14_-_99737565 0.113 ENST00000357195.3
 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr7_-_111846435 0.110 ENST00000437633.1
ENST00000428084.1
 DOCK4

dedicator of cytokinesis 4

chr10_+_52751010 0.110 ENST00000373985.1
 PRKG1
protein kinase, cGMP-dependent, type I
chrX_-_109561294 0.110 ENST00000372059.2
ENST00000262844.5
 AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr5_-_142783175 0.110 ENST00000231509.3
ENST00000394464.2
 NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr11_+_64073699 0.107 ENST00000405666.1
ENST00000468670.1
 ESRRA

estrogen-related receptor alpha

chr2_+_46524537 0.106 ENST00000263734.3
 EPAS1
endothelial PAS domain protein 1
chr3_-_48632593 0.103 ENST00000454817.1
ENST00000328333.8
 COL7A1

collagen, type VII, alpha 1

chr7_-_14029515 0.092 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
 ETV1


ets variant 1


chr1_-_244013384 0.091 ENST00000366539.1
 AKT3
v-akt murine thymoma viral oncogene homolog 3
chr2_-_153574480 0.091 ENST00000410080.1
 PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr11_-_27528301 0.087 ENST00000524596.1
ENST00000278193.2
 LIN7C

lin-7 homolog C (C. elegans)

chr17_+_68165657 0.086 ENST00000243457.3
 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr5_+_74632993 0.080 ENST00000287936.4
 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr3_-_113465065 0.079 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
 NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr2_+_173600671 0.077 ENST00000409036.1
 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_-_151217001 0.077 ENST00000262187.5
 RHEB
Ras homolog enriched in brain
chr15_+_41523335 0.076 ENST00000334660.5
 CHP1
calcineurin-like EF-hand protein 1
chr17_-_19771216 0.067 ENST00000395544.4
 ULK2
unc-51 like autophagy activating kinase 2
chr10_-_103874692 0.066 ENST00000361198.5
 LDB1
LIM domain binding 1
chrX_+_69664706 0.057 ENST00000194900.4
ENST00000374360.3
 DLG3

discs, large homolog 3 (Drosophila)

chr12_+_56137064 0.056 ENST00000257868.5
ENST00000546799.1
 GDF11

growth differentiation factor 11

chr11_-_102714534 0.055 ENST00000299855.5
 MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr3_-_55523966 0.055 ENST00000474267.1
 WNT5A
wingless-type MMTV integration site family, member 5A
chr11_-_68609377 0.055 ENST00000265641.5
ENST00000376618.2
 CPT1A

carnitine palmitoyltransferase 1A (liver)

chr1_-_155211017 0.055 ENST00000536770.1
ENST00000368373.3
 GBA

glucosidase, beta, acid

chr13_-_21476900 0.054 ENST00000400602.2
ENST00000255305.6
 XPO4

exportin 4

chr12_-_67072714 0.054 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
 GRIP1




glutamate receptor interacting protein 1




chr1_+_2985760 0.052 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
 PRDM16


PR domain containing 16


chr20_-_39317868 0.052 ENST00000373313.2
 MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr2_-_157189180 0.048 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
 NR4A2




nuclear receptor subfamily 4, group A, member 2




chr2_-_43453734 0.048 ENST00000282388.3
 ZFP36L2
ZFP36 ring finger protein-like 2
chr1_-_38325256 0.047 ENST00000373036.4
 MTF1
metal-regulatory transcription factor 1
chr20_-_1974692 0.046 ENST00000217305.2
ENST00000539905.1
 PDYN

prodynorphin

chr9_+_128024067 0.044 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
 GAPVD1









GTPase activating protein and VPS9 domains 1









chr13_+_114238997 0.042 ENST00000538138.1
ENST00000375370.5
 TFDP1

transcription factor Dp-1

chr22_+_21271714 0.042 ENST00000354336.3
 CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr15_-_64995399 0.041 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
 OAZ2



ornithine decarboxylase antizyme 2



chrX_+_73641286 0.041 ENST00000587091.1
 SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr3_+_14989076 0.041 ENST00000413118.1
ENST00000425241.1
 NR2C2

nuclear receptor subfamily 2, group C, member 2

chr3_+_101292939 0.039 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
 PCNP


PEST proteolytic signal containing nuclear protein


chr3_+_152552685 0.039 ENST00000305097.3
 P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr1_+_156589051 0.039 ENST00000255039.1
 HAPLN2
hyaluronan and proteoglycan link protein 2
chr10_+_22605304 0.038 ENST00000456711.1
ENST00000444869.1
ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
 COMMD3

COMMD3-BMI1


COMM domain containing 3

COMMD3-BMI1 readthrough


chr7_+_139044621 0.038 ENST00000354926.4
 C7orf55-LUC7L2
C7orf55-LUC7L2 readthrough
chr4_+_41992489 0.037 ENST00000264451.7
 SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr17_+_36508111 0.036 ENST00000331159.5
ENST00000577233.1
 SOCS7

suppressor of cytokine signaling 7

chr11_+_66036004 0.036 ENST00000311481.6
ENST00000527397.1
 RAB1B

RAB1B, member RAS oncogene family

chr10_+_22610124 0.036 ENST00000376663.3
 BMI1
BMI1 polycomb ring finger oncogene
chr2_+_192542850 0.035 ENST00000410026.2
 NABP1
nucleic acid binding protein 1
chr10_+_101419187 0.034 ENST00000370489.4
 ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr1_+_64239657 0.033 ENST00000371080.1
ENST00000371079.1
 ROR1

receptor tyrosine kinase-like orphan receptor 1

chr2_-_208634287 0.032 ENST00000295417.3
 FZD5
frizzled family receptor 5
chr1_-_35658736 0.031 ENST00000357214.5
 SFPQ
splicing factor proline/glutamine-rich
chr3_-_48885228 0.030 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
 PRKAR2A



protein kinase, cAMP-dependent, regulatory, type II, alpha



chr11_+_63606373 0.030 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
 MARK2




MAP/microtubule affinity-regulating kinase 2




chr22_-_42017021 0.029 ENST00000263256.6
 DESI1
desumoylating isopeptidase 1
chr4_+_139936905 0.029 ENST00000280614.2
 CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr20_+_56884752 0.028 ENST00000244040.3
 RAB22A
RAB22A, member RAS oncogene family
chr1_+_161284047 0.027 ENST00000367975.2
ENST00000342751.4
ENST00000432287.2
ENST00000392169.2
ENST00000513009.1
 SDHC




succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa




chr12_-_89918522 0.027 ENST00000529983.2
 GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr8_+_1449532 0.026 ENST00000421627.2
 DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chrX_-_83442915 0.024 ENST00000262752.2
ENST00000543399.1
 RPS6KA6

ribosomal protein S6 kinase, 90kDa, polypeptide 6

chr12_+_66217911 0.024 ENST00000403681.2
 HMGA2
high mobility group AT-hook 2
chr1_-_155881156 0.023 ENST00000539040.1
ENST00000368323.3
 RIT1

Ras-like without CAAX 1

chr10_-_120101804 0.021 ENST00000369183.4
ENST00000369172.4
 FAM204A

family with sequence similarity 204, member A

chr2_+_155554797 0.021 ENST00000295101.2
 KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr10_-_120514720 0.021 ENST00000369151.3
ENST00000340214.4
 CACUL1

CDK2-associated, cullin domain 1

chr18_+_43753974 0.019 ENST00000282059.6
ENST00000321319.6
 C18orf25

chromosome 18 open reading frame 25

chr2_-_39348137 0.017 ENST00000426016.1
 SOS1
son of sevenless homolog 1 (Drosophila)
chr8_+_59323823 0.017 ENST00000399598.2
 UBXN2B
UBX domain protein 2B
chr1_+_202976493 0.015 ENST00000367242.3
 TMEM183A
transmembrane protein 183A
chr1_-_205719295 0.015 ENST00000367142.4
 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_-_39339777 0.014 ENST00000397572.2
 MYCBP
MYC binding protein
chr12_-_75905374 0.014 ENST00000438169.2
ENST00000229214.4
 KRR1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr17_-_40273348 0.014 ENST00000225916.5
 KAT2A
K(lysine) acetyltransferase 2A
chr12_+_2162447 0.014 ENST00000335762.5
ENST00000399655.1
 CACNA1C

calcium channel, voltage-dependent, L type, alpha 1C subunit

chr4_-_103748880 0.013 ENST00000453744.2
ENST00000349311.8
 UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr2_+_131862900 0.013 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
 PLEKHB2


pleckstrin homology domain containing, family B (evectins) member 2


chr1_+_36273743 0.012 ENST00000373210.3
 AGO4
argonaute RISC catalytic component 4
chr12_+_56401268 0.012 ENST00000262032.5
 IKZF4
IKAROS family zinc finger 4 (Eos)
chr9_+_130548297 0.012 ENST00000373264.4
 CDK9
cyclin-dependent kinase 9
chr12_-_89919965 0.012 ENST00000548729.1
 POC1B-GALNT4
POC1B-GALNT4 readthrough
chr7_+_6414128 0.009 ENST00000348035.4
ENST00000356142.4
 RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

chr17_-_56084578 0.009 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
 SRSF1



serine/arginine-rich splicing factor 1



chr9_+_131445928 0.008 ENST00000372692.4
 SET
SET nuclear oncogene
chr12_+_69864129 0.008 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
 FRS2









fibroblast growth factor receptor substrate 2









chr1_+_145611010 0.008 ENST00000369291.5
 RNF115
ring finger protein 115
chr7_-_32931387 0.007 ENST00000304056.4
 KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr8_-_57906362 0.007 ENST00000262644.4
 IMPAD1
inositol monophosphatase domain containing 1
chr12_-_82153087 0.004 ENST00000547623.1
ENST00000549396.1
 PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr11_+_48002076 0.003 ENST00000418331.2
ENST00000440289.2
 PTPRJ

protein tyrosine phosphatase, receptor type, J

chr7_+_28452130 0.002 ENST00000357727.2
 CREB5
cAMP responsive element binding protein 5
chrX_+_77359671 0.002 ENST00000373316.4
 PGK1
phosphoglycerate kinase 1
chr3_+_51575596 0.002 ENST00000409535.2
 RAD54L2
RAD54-like 2 (S. cerevisiae)
chr19_+_46850251 0.001 ENST00000012443.4
 PPP5C
protein phosphatase 5, catalytic subunit
chr18_+_32073253 0.000 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA


dystrobrevin, alpha



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.1 0.4 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0009642 response to light intensity(GO:0009642) response to vitamin E(GO:0033197)
0.0 0.2 GO:0060839 radial pattern formation(GO:0009956) lymphatic endothelial cell fate commitment(GO:0060838) endothelial cell fate commitment(GO:0060839) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.2 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)