Motif ID: BBX

Z-value: 0.874


Transcription factors associated with BBX:

Gene SymbolEntrez IDGene Name
BBX ENSG00000114439.14 BBX



Activity profile for motif BBX.

activity profile for motif BBX


Sorted Z-values histogram for motif BBX

Sorted Z-values for motif BBX



Network of associatons between targets according to the STRING database.



First level regulatory network of BBX

PNG image of the network

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Top targets:


Showing 1 to 20 of 65 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_155484155 2.341 ENST00000509493.1
 FGB
fibrinogen beta chain
chr9_-_116837249 2.109 ENST00000466610.2
 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_155484103 1.795 ENST00000302068.4
 FGB
fibrinogen beta chain
chr4_-_70080449 1.499 ENST00000446444.1
 UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr9_-_5833027 1.171 ENST00000339450.5
 ERMP1
endoplasmic reticulum metallopeptidase 1
chr4_-_186697044 0.958 ENST00000437304.2
 SORBS2
sorbin and SH3 domain containing 2
chr6_+_31895254 0.945 ENST00000299367.5
ENST00000442278.2
 C2

complement component 2

chr11_+_22689648 0.933 ENST00000278187.3
 GAS2
growth arrest-specific 2
chr4_-_186733363 0.881 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2


sorbin and SH3 domain containing 2


chr4_-_186696425 0.751 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2


sorbin and SH3 domain containing 2


chr12_-_52887034 0.718 ENST00000330722.6
 KRT6A
keratin 6A
chr22_+_44319619 0.647 ENST00000216180.3
 PNPLA3
patatin-like phospholipase domain containing 3
chr16_+_56672571 0.608 ENST00000290705.8
 MT1A
metallothionein 1A
chr13_+_50570019 0.597 ENST00000442421.1
 TRIM13
tripartite motif containing 13
chr1_-_59043166 0.366 ENST00000371225.2
 TACSTD2
tumor-associated calcium signal transducer 2
chr14_+_23235886 0.366 ENST00000604262.1
ENST00000431881.2
ENST00000412791.1
ENST00000358043.5
 OXA1L



oxidase (cytochrome c) assembly 1-like



chr1_+_229440129 0.350 ENST00000366688.3
 SPHAR
S-phase response (cyclin related)
chr16_+_28763108 0.342 ENST00000357796.3
ENST00000550983.1
 NPIPB9

nuclear pore complex interacting protein family, member B9

chr5_-_78809950 0.320 ENST00000334082.6
 HOMER1
homer homolog 1 (Drosophila)
chr1_+_55464600 0.304 ENST00000371265.4
 BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.1 GO:0051592 response to calcium ion(GO:0051592)
0.2 2.1 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 1.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.7 GO:0007398 ectoderm development(GO:0007398)
0.1 0.6 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.6 GO:0036503 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503) protein autoubiquitination(GO:0051865)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 3.6 GO:0005792 obsolete microsome(GO:0005792)
0.1 2.9 GO:0030018 Z disc(GO:0030018)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.1 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 2.1 GO:0019862 IgA binding(GO:0019862)
0.0 1.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.6 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.2 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.