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ENCODE cell lines, expression (Ernst 2011)
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Results for AGCACCA
Z-value: 1.76
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miRNA associated with seed AGCACCA
Network of associatons between targets according to the STRING database.
First level regulatory network of AGCACCA
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_94023873 | 5.85 |
ENST00000297268.6 |
COL1A2 |
collagen, type I, alpha 2 |
| chr2_+_189839046 | 5.73 |
ENST00000304636.3 ENST00000317840.5 |
COL3A1 |
collagen, type III, alpha 1 |
| chr15_+_81071684 | 5.33 |
ENST00000220244.3 ENST00000394685.3 ENST00000356249.5 |
KIAA1199 |
KIAA1199 |
| chr3_-_120170052 | 4.81 |
ENST00000295633.3 |
FSTL1 |
follistatin-like 1 |
| chr7_+_130126012 | 4.42 |
ENST00000341441.5 |
MEST |
mesoderm specific transcript |
| chr9_+_137533615 | 4.37 |
ENST00000371817.3 |
COL5A1 |
collagen, type V, alpha 1 |
| chr15_-_48937982 | 4.35 |
ENST00000316623.5 |
FBN1 |
fibrillin 1 |
| chr21_-_28338732 | 4.20 |
ENST00000284987.5 |
ADAMTS5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| chr2_-_238323007 | 3.88 |
ENST00000295550.4 |
COL6A3 |
collagen, type VI, alpha 3 |
| chr1_-_103574024 | 3.87 |
ENST00000512756.1 ENST00000370096.3 ENST00000358392.2 ENST00000353414.4 |
COL11A1 |
collagen, type XI, alpha 1 |
Gene Ontology Analysis
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 23.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 14.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 6.0 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 5.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 4.8 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.1 | 4.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.6 | 4.3 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.0 | 4.1 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 3.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.7 | 3.6 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 36.4 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 14.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 6.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.8 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 5.6 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 4.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 4.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 3.1 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 2.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 2.1 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 19.6 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 2.1 | 19.0 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 3.2 | 9.7 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 7.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.3 | 5.7 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 5.4 | GO:0005924 | cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) |
| 0.5 | 4.6 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 0.3 | 3.9 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 3.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 3.5 | GO:0005901 | caveola(GO:0005901) |
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 17.6 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 2.1 | 8.2 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 1.4 | 6.9 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.7 | 5.7 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.9 | 4.3 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
| 0.0 | 4.0 | GO:0030509 | BMP signaling pathway(GO:0030509) |
| 0.8 | 3.9 | GO:0035989 | tendon development(GO:0035989) |
| 0.4 | 3.8 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.1 | 3.6 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.0 | 3.5 | GO:0007498 | mesoderm development(GO:0007498) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 39.1 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 6.6 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 6.1 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 4.4 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 3.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 3.2 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 3.0 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 3.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 2.7 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 2.3 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |