ISMARA results: AR

Project

ENCODE cell lines, expression (Ernst 2011)

Navigation

Downloads

Results for AR_NR3C2

Z-value: 1.30

Motif logo

Transcription factors associated with AR_NR3C2

Gene Symbol	Gene ID	Gene Info
AR Ensembl NCBI GeneCards UniProt	ENSG00000169083.11	AR
NR3C2 Ensembl NCBI GeneCards UniProt	ENSG00000151623.10	NR3C2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
AR	hg19_v2_chrX_+_66764375_66764465	0.29	2.7e-01	Click!
NR3C2	hg19_v2_chr4_-_149365827_149365870, hg19_v2_chr4_-_149363662_149363688	0.16	5.5e-01	Click!

Activity profile of AR_NR3C2 motif

Sorted Z-values of AR_NR3C2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AR_NR3C2

View svg image
View png image

Top targets:

Search:

Show entries

Promoter	Score	Transcript	Gene	Gene Info
chr16_+_56659687	8.85	ENST00000568293.1 ENST00000330439.6	MT1E	metallothionein 1E
chr16_+_56642041	7.52	ENST00000245185.5	MT2A	metallothionein 2A
chr16_+_56642489	6.60	ENST00000561491.1	MT2A	metallothionein 2A
chr16_+_56716336	6.21	ENST00000394485.4 ENST00000562939.1	MT1X	metallothionein 1X
chr8_-_49834299	5.21	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr8_-_49833978	4.83	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr7_-_94285402	3.04	ENST00000428696.2 ENST00000445866.2	SGCE	sarcoglycan, epsilon
chr7_-_94285511	3.03	ENST00000265735.7	SGCE	sarcoglycan, epsilon
chr2_+_238395879	2.84	ENST00000445024.2 ENST00000338530.4 ENST00000409373.1	MLPH	melanophilin
chr2_+_238395803	2.74	ENST00000264605.3	MLPH	melanophilin

Showing 1 to 10 of 79 entries

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	14.1	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	9.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	4.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	4.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network

Showing 1 to 4 of 4 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	20.1	GO:0008270	zinc ion binding(GO:0008270)
1.1	14.1	GO:0046870	cadmium ion binding(GO:0046870)
0.1	9.9	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	5.6	GO:0017022	myosin binding(GO:0017022)
0.1	4.9	GO:0042056	chemoattractant activity(GO:0042056)
0.1	4.9	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	1.1	GO:0035877	death effector domain binding(GO:0035877)
0.1	1.0	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.7	GO:0017080	sodium channel regulator activity(GO:0017080)

Showing 1 to 10 of 19 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	14.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.2	4.9	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators

Showing 1 to 5 of 5 entries

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	14.2	GO:0071294	cellular response to zinc ion(GO:0071294)
2.8	14.1	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
3.3	10.0	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0	6.8	GO:0007160	cell-matrix adhesion(GO:0007160)
1.0	6.2	GO:0036018	cellular response to erythropoietin(GO:0036018)
0.4	5.6	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.6	4.9	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1	4.9	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.4	1.1	GO:0014876	response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2	1.0	GO:0034201	response to oleic acid(GO:0034201)

Showing 1 to 10 of 24 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	30.5	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
1.0	7.6	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	7.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	5.6	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.2	4.9	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	4.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	1.1	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.7	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.5	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.5	GO:0071953	elastic fiber(GO:0071953)

Showing 1 to 10 of 13 entries

Results for AR_NR3C2

Z-value: 1.30

Motif logo

Transcription factors associated with AR_NR3C2

Activity-expression correlation:

Activity profile of AR_NR3C2 motif

Sorted Z-values of AR_NR3C2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AR_NR3C2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category: