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ENCODE cell lines, expression (Ernst 2011)
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Results for BATF
Z-value: 1.39
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Transcription factors associated with BATF
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BATF | hg19_v2_chr14_+_75988768_75988826 | -0.11 | 6.8e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of BATF
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_+_21452804 | 9.61 |
ENST00000269217.6 |
LAMA3 |
laminin, alpha 3 |
| chr18_+_21452964 | 8.61 |
ENST00000587184.1 |
LAMA3 |
laminin, alpha 3 |
| chr1_-_209824643 | 5.12 |
ENST00000391911.1 ENST00000415782.1 |
LAMB3 |
laminin, beta 3 |
| chr12_-_52845910 | 4.85 |
ENST00000252252.3 |
KRT6B |
keratin 6B |
| chr18_+_61442629 | 4.03 |
ENST00000398019.2 ENST00000540675.1 |
SERPINB7 |
serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
| chr2_-_113594279 | 4.01 |
ENST00000416750.1 ENST00000418817.1 ENST00000263341.2 |
IL1B |
interleukin 1, beta |
| chr19_-_51504411 | 3.81 |
ENST00000593490.1 |
KLK8 |
kallikrein-related peptidase 8 |
| chr1_-_151965048 | 3.73 |
ENST00000368809.1 |
S100A10 |
S100 calcium binding protein A10 |
| chr1_+_153003671 | 3.18 |
ENST00000307098.4 |
SPRR1B |
small proline-rich protein 1B |
| chr17_-_39769005 | 3.17 |
ENST00000301653.4 ENST00000593067.1 |
KRT16 |
keratin 16 |
Gene Ontology Analysis
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.7 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 1.6 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.1 | 0.8 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.2 | 0.7 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.2 | 0.5 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 0.0 | 0.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.4 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 0.3 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 0.0 | 0.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.2 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.1 | 2.4 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.0 | 1.6 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
| 0.1 | 0.8 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 0.1 | 0.8 | GO:0000050 | urea cycle(GO:0000050) |
| 0.0 | 0.7 | GO:0007567 | parturition(GO:0007567) |
| 0.0 | 0.5 | GO:0071028 | nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.0 | 0.5 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.5 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.0 | 0.4 | GO:0002076 | osteoblast development(GO:0002076) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 23.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.2 | 11.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 6.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.3 | 5.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 4.6 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 4.3 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 4.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 3.4 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 3.2 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.3 | 3.1 | GO:0030057 | desmosome(GO:0030057) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.6 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.0 | 1.1 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.4 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 0.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.3 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.1 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 0.1 | GO:0070652 | HAUS complex(GO:0070652) |
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 28.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 10.2 | GO:0070268 | cornification(GO:0070268) |
| 1.6 | 6.4 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.1 | 6.2 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.2 | 4.9 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.1 | 4.9 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.2 | 4.7 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.4 | 4.5 | GO:0002934 | desmosome organization(GO:0002934) |
| 1.1 | 4.4 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.2 | 4.4 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 24.5 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.2 | 18.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.3 | 7.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.4 | 7.2 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 6.9 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 1.3 | 6.5 | GO:0052828 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.9 | 3.7 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.7 | 3.4 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.2 | 3.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 3.2 | GO:0044325 | ion channel binding(GO:0044325) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 27.9 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 8.3 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.4 | 5.9 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 4.3 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 4.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.3 | 3.7 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 3.0 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 2.4 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 2.4 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 2.2 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 27.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 11.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 8.4 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 5.3 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.2 | 4.7 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 4.7 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 4.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 3.7 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 3.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |