ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CEBPB Links Ensembl NCBI GeneCards UniProt	ENSG00000172216.4	CEBPB

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPB	hg19_v2_chr20_+_48807351_48807384	0.65	6.9e-03	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr17_-_64216748	7.71	ENST00000585162.1	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr17_+_1665253	6.07	ENST00000254722.4	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665345	5.26	ENST00000576406.1 ENST00000571149.1	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr4_-_155533787	4.79	ENST00000407946.1 ENST00000405164.1 ENST00000336098.3 ENST00000393846.2 ENST00000404648.3 ENST00000443553.1	FGG	fibrinogen gamma chain
chr2_-_216300784	4.24	ENST00000421182.1 ENST00000432072.2 ENST00000323926.6 ENST00000336916.4 ENST00000357867.4 ENST00000359671.1 ENST00000346544.3 ENST00000345488.5 ENST00000357009.2 ENST00000446046.1 ENST00000356005.4 ENST00000443816.1 ENST00000426059.1 ENST00000354785.4	FN1	fibronectin 1
chr3_-_49722523	3.69	ENST00000448220.1	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)
chr5_+_150400124	3.50	ENST00000388825.4 ENST00000521650.1 ENST00000517973.1	GPX3	glutathione peroxidase 3 (plasma)
chr5_-_172756506	3.35	ENST00000265087.4	STC2	stanniocalcin 2
chr6_+_31895467	3.33	ENST00000556679.1 ENST00000456570.1	CFB CFB	complement factor B Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895254	3.31	ENST00000299367.5 ENST00000442278.2	C2	complement component 2
chr1_+_212782012	3.24	ENST00000341491.4 ENST00000366985.1	ATF3	activating transcription factor 3
chr6_+_31895480	3.20	ENST00000418949.2 ENST00000383177.3 ENST00000477310.1	C2 CFB	complement component 2 Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr12_+_57849048	3.10	ENST00000266646.2	INHBE	inhibin, beta E
chr2_-_160654745	3.10	ENST00000259053.4 ENST00000429078.2	CD302	CD302 molecule
chr3_+_12392971	3.04	ENST00000287820.6	PPARG	peroxisome proliferator-activated receptor gamma
chr22_+_35776828	2.75	ENST00000216117.8	HMOX1	heme oxygenase (decycling) 1
chr20_+_56136136	2.75	ENST00000319441.4 ENST00000543666.1	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr16_+_72088376	2.68	ENST00000570083.1 ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5	HP HPR	haptoglobin haptoglobin-related protein
chr17_+_53342311	2.66	ENST00000226067.5	HLF	hepatic leukemia factor
chr5_-_141704566	2.50	ENST00000344120.4 ENST00000434127.2	SPRY4	sprouty homolog 4 (Drosophila)
chrX_+_115567767	2.39	ENST00000371900.4	SLC6A14	solute carrier family 6 (amino acid transporter), member 14
chr3_-_99833333	2.28	ENST00000354552.3 ENST00000331335.5 ENST00000398326.2	FILIP1L	filamin A interacting protein 1-like
chr3_+_157154578	2.11	ENST00000295927.3	PTX3	pentraxin 3, long
chr2_+_211421262	1.86	ENST00000233072.5	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr2_-_175711133	1.86	ENST00000409597.1 ENST00000413882.1	CHN1	chimerin 1
chr14_-_92413727	1.81	ENST00000267620.10	FBLN5	fibulin 5
chr11_+_7506713	1.77	ENST00000329293.3 ENST00000534244.1	OLFML1	olfactomedin-like 1
chr20_+_361261	1.74	ENST00000217233.3	TRIB3	tribbles pseudokinase 3
chr1_+_99127225	1.68	ENST00000370189.5 ENST00000529992.1	SNX7	sorting nexin 7
chr14_-_92413353	1.67	ENST00000556154.1	FBLN5	fibulin 5
chr3_-_66551397	1.63	ENST00000383703.3	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
chr10_+_101542462	1.59	ENST00000370449.4 ENST00000370434.1	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr4_+_71063641	1.58	ENST00000514097.1	ODAM	odontogenic, ameloblast asssociated
chr19_+_11350278	1.57	ENST00000252453.8	C19orf80	chromosome 19 open reading frame 80
chr3_-_66551351	1.54	ENST00000273261.3	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
chr12_-_6451186	1.49	ENST00000540022.1 ENST00000536194.1	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A
chr21_-_44495964	1.46	ENST00000398168.1 ENST00000398165.3	CBS	cystathionine-beta-synthase
chr19_-_51869592	1.36	ENST00000596253.1 ENST00000309244.4	ETFB	electron-transfer-flavoprotein, beta polypeptide
chr16_-_28550348	1.36	ENST00000324873.6	NUPR1	nuclear protein, transcriptional regulator, 1
chr20_+_8112824	1.36	ENST00000378641.3	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr12_-_96390063	1.33	ENST00000541929.1	HAL	histidine ammonia-lyase
chr21_-_44495919	1.33	ENST00000398158.1	CBS	cystathionine-beta-synthase
chr16_-_28550320	1.25	ENST00000395641.2	NUPR1	nuclear protein, transcriptional regulator, 1
chrX_-_106243451	1.25	ENST00000355610.4 ENST00000535534.1	MORC4	MORC family CW-type zinc finger 4
chr12_+_10366016	1.22	ENST00000546017.1 ENST00000535576.1 ENST00000539170.1	GABARAPL1	GABA(A) receptor-associated protein like 1
chr3_+_138067521	1.20	ENST00000494949.1	MRAS	muscle RAS oncogene homolog
chr1_-_36948879	1.17	ENST00000373106.1 ENST00000373104.1 ENST00000373103.1	CSF3R	colony stimulating factor 3 receptor (granulocyte)
chr16_-_57809015	1.16	ENST00000540079.2 ENST00000569222.1	KIFC3	kinesin family member C3
chr4_+_113739244	1.13	ENST00000503271.1 ENST00000503423.1 ENST00000506722.1	ANK2	ankyrin 2, neuronal
chr12_-_6451235	1.12	ENST00000440083.2 ENST00000162749.2	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A
chr1_+_150954493	1.09	ENST00000368947.4	ANXA9	annexin A9
chr12_-_57914275	1.07	ENST00000547303.1 ENST00000552740.1 ENST00000547526.1 ENST00000551116.1 ENST00000346473.3	DDIT3	DNA-damage-inducible transcript 3
chr12_-_96390108	1.01	ENST00000538703.1 ENST00000261208.3	HAL	histidine ammonia-lyase
chrX_+_9431324	1.00	ENST00000407597.2 ENST00000424279.1 ENST00000536365.1 ENST00000441088.1 ENST00000380961.1 ENST00000415293.1	TBL1X	transducin (beta)-like 1X-linked
chr19_-_33360647	0.96	ENST00000590341.1 ENST00000587772.1 ENST00000023064.4	SLC7A9	solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr4_-_139163491	0.93	ENST00000280612.5	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_+_57623869	0.92	ENST00000414700.3 ENST00000557703.1	SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)
chr17_-_76836729	0.89	ENST00000587783.1 ENST00000542802.3 ENST00000586531.1 ENST00000589424.1 ENST00000590546.2	USP36	ubiquitin specific peptidase 36
chr12_+_57623477	0.86	ENST00000557487.1 ENST00000555634.1 ENST00000556689.1	SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)
chr2_+_113885138	0.84	ENST00000409930.3	IL1RN	interleukin 1 receptor antagonist
chr7_-_50860565	0.84	ENST00000403097.1	GRB10	growth factor receptor-bound protein 10
chr19_-_44124019	0.83	ENST00000300811.3	ZNF428	zinc finger protein 428
chr17_-_76836963	0.80	ENST00000312010.6	USP36	ubiquitin specific peptidase 36
chr17_-_79895154	0.78	ENST00000405481.4 ENST00000585215.1 ENST00000577624.1 ENST00000403172.4	PYCR1	pyrroline-5-carboxylate reductase 1
chr7_-_76829125	0.75	ENST00000248598.5	FGL2	fibrinogen-like 2
chr1_-_36945097	0.73	ENST00000331941.5 ENST00000418048.2 ENST00000338937.5 ENST00000440588.2	CSF3R	colony stimulating factor 3 receptor (granulocyte)
chr11_+_73019282	0.70	ENST00000263674.3	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17
chr12_+_56390964	0.68	ENST00000356124.4 ENST00000266971.3 ENST00000394115.2 ENST00000547586.1 ENST00000552258.1 ENST00000548274.1 ENST00000546833.1	SUOX	sulfite oxidase
chr5_-_35230434	0.66	ENST00000504500.1	PRLR	prolactin receptor
chr17_-_79895097	0.66	ENST00000402252.2 ENST00000583564.1 ENST00000585244.1 ENST00000337943.5 ENST00000579698.1	PYCR1	pyrroline-5-carboxylate reductase 1
chr12_+_57914742	0.64	ENST00000551351.1	MBD6	methyl-CpG binding domain protein 6
chr1_+_203595903	0.64	ENST00000367218.3 ENST00000367219.3 ENST00000391954.2	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr19_-_44123734	0.62	ENST00000598676.1	ZNF428	zinc finger protein 428
chr12_+_57624119	0.62	ENST00000555773.1 ENST00000554975.1 ENST00000449049.3 ENST00000393827.4	SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)
chr9_-_13175823	0.60	ENST00000545857.1	MPDZ	multiple PDZ domain protein
chr5_+_52083730	0.58	ENST00000282588.6 ENST00000274311.2	ITGA1 PELO	integrin, alpha 1 pelota homolog (Drosophila)
chr11_-_3078616	0.56	ENST00000401769.3 ENST00000278224.9 ENST00000397114.3 ENST00000380525.4	CARS	cysteinyl-tRNA synthetase
chr3_+_186435137	0.56	ENST00000447445.1	KNG1	kininogen 1
chr1_+_164528866	0.53	ENST00000420696.2	PBX1	pre-B-cell leukemia homeobox 1
chr17_+_56315936	0.52	ENST00000543544.1	LPO	lactoperoxidase
chr19_-_11347173	0.52	ENST00000587656.1	DOCK6	dedicator of cytokinesis 6
chr4_-_153601136	0.52	ENST00000504064.1 ENST00000304385.3	TMEM154	transmembrane protein 154
chr11_+_47279504	0.52	ENST00000441012.2 ENST00000437276.1 ENST00000436029.1 ENST00000467728.1 ENST00000405853.3	NR1H3	nuclear receptor subfamily 1, group H, member 3
chr15_+_96869165	0.51	ENST00000421109.2	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr2_+_65216462	0.51	ENST00000234256.3	SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_+_203595689	0.50	ENST00000357681.5	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr6_+_126102292	0.49	ENST00000368357.3	NCOA7	nuclear receptor coactivator 7
chr12_-_123187890	0.48	ENST00000328880.5	HCAR2	hydroxycarboxylic acid receptor 2
chr1_+_53480598	0.47	ENST00000430330.2 ENST00000408941.3 ENST00000478274.2 ENST00000484100.1 ENST00000435345.2 ENST00000488965.1	SCP2	sterol carrier protein 2
chr2_+_171785012	0.46	ENST00000234160.4	GORASP2	golgi reassembly stacking protein 2, 55kDa
chr10_+_111765562	0.46	ENST00000360162.3	ADD3	adducin 3 (gamma)
chr12_+_57624085	0.45	ENST00000553474.1	SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)
chr6_-_31939734	0.43	ENST00000375356.3	DXO	decapping exoribonuclease
chr16_-_15736881	0.43	ENST00000540441.2	KIAA0430	KIAA0430
chr15_-_61521495	0.41	ENST00000335670.6	RORA	RAR-related orphan receptor A
chr2_+_187350973	0.41	ENST00000544130.1	ZC3H15	zinc finger CCCH-type containing 15
chr12_-_56236690	0.40	ENST00000322569.4	MMP19	matrix metallopeptidase 19
chr20_+_2821340	0.39	ENST00000380445.3 ENST00000380469.3	VPS16	vacuolar protein sorting 16 homolog (S. cerevisiae)
chr2_+_28618532	0.38	ENST00000545753.1	FOSL2	FOS-like antigen 2
chr1_-_149908217	0.38	ENST00000369140.3	MTMR11	myotubularin related protein 11
chr1_+_52682052	0.38	ENST00000371591.1	ZFYVE9	zinc finger, FYVE domain containing 9
chr18_+_46065393	0.36	ENST00000256413.3	CTIF	CBP80/20-dependent translation initiation factor
chr14_+_39735411	0.35	ENST00000603904.1	RP11-407N17.3	cTAGE family member 5 isoform 4
chr1_-_149908710	0.34	ENST00000439741.2 ENST00000361405.6 ENST00000406732.3	MTMR11	myotubularin related protein 11
chr1_+_221051699	0.33	ENST00000366903.6	HLX	H2.0-like homeobox
chr10_-_101190202	0.32	ENST00000543866.1 ENST00000370508.5	GOT1	glutamic-oxaloacetic transaminase 1, soluble
chr19_+_1105110	0.31	ENST00000587648.1	GPX4	glutathione peroxidase 4
chr2_-_43453734	0.30	ENST00000282388.3	ZFP36L2	ZFP36 ring finger protein-like 2
chr19_-_4540486	0.28	ENST00000306390.6	LRG1	leucine-rich alpha-2-glycoprotein 1
chr11_-_102668879	0.28	ENST00000315274.6	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_6644443	0.28	ENST00000396858.1	GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr3_+_138067314	0.27	ENST00000423968.2	MRAS	muscle RAS oncogene homolog
chr22_+_39052632	0.26	ENST00000411557.1 ENST00000396811.2 ENST00000216029.3 ENST00000416285.1	CBY1	chibby homolog 1 (Drosophila)
chr2_+_5832799	0.26	ENST00000322002.3	SOX11	SRY (sex determining region Y)-box 11
chr1_-_23857698	0.25	ENST00000361729.2	E2F2	E2F transcription factor 2
chr6_+_31939608	0.24	ENST00000375331.2 ENST00000375333.2	STK19	serine/threonine kinase 19
chr3_-_138763734	0.24	ENST00000413199.1 ENST00000502927.2	PRR23C	proline rich 23C
chr10_+_57358750	0.23	ENST00000512524.2	MTRNR2L5	MT-RNR2-like 5
chrX_-_43832711	0.23	ENST00000378062.5	NDP	Norrie disease (pseudoglioma)
chr17_-_77813186	0.23	ENST00000448310.1 ENST00000269397.4	CBX4	chromobox homolog 4
chr22_-_39640756	0.22	ENST00000331163.6	PDGFB	platelet-derived growth factor beta polypeptide
chr2_+_187350883	0.21	ENST00000337859.6	ZC3H15	zinc finger CCCH-type containing 15
chr11_+_63655987	0.21	ENST00000509502.2 ENST00000512060.1	MARK2	MAP/microtubule affinity-regulating kinase 2
chr11_-_3078838	0.21	ENST00000397111.5	CARS	cysteinyl-tRNA synthetase
chr6_+_36238237	0.21	ENST00000457797.1 ENST00000394571.2	PNPLA1	patatin-like phospholipase domain containing 1
chr19_-_47288162	0.21	ENST00000594991.1	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5
chr1_-_216978709	0.20	ENST00000360012.3	ESRRG	estrogen-related receptor gamma
chr12_-_123201337	0.19	ENST00000528880.2	HCAR3	hydroxycarboxylic acid receptor 3
chr19_-_47287990	0.18	ENST00000593713.1 ENST00000598022.1 ENST00000434726.2	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5
chr9_+_2621798	0.18	ENST00000382100.3	VLDLR	very low density lipoprotein receptor
chr10_+_95848824	0.17	ENST00000371385.3 ENST00000371375.1	PLCE1	phospholipase C, epsilon 1
chr17_+_56315787	0.16	ENST00000262290.4 ENST00000421678.2	LPO	lactoperoxidase
chr2_-_217559517	0.16	ENST00000449583.1	IGFBP5	insulin-like growth factor binding protein 5
chr16_+_56965960	0.15	ENST00000439977.2 ENST00000344114.4 ENST00000300302.5 ENST00000379792.2	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr16_+_89334512	0.14	ENST00000602042.1	AC137932.1	AC137932.1
chr5_-_35230649	0.13	ENST00000382002.5	PRLR	prolactin receptor
chr5_+_38846101	0.12	ENST00000274276.3	OSMR	oncostatin M receptor
chr5_-_137878887	0.11	ENST00000507939.1 ENST00000572514.1 ENST00000499810.2 ENST00000360541.5	ETF1	eukaryotic translation termination factor 1
chr14_-_25045446	0.10	ENST00000216336.2	CTSG	cathepsin G
chr16_-_4323015	0.10	ENST00000204517.6	TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr5_-_158757895	0.09	ENST00000231228.2	IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr17_+_39846114	0.08	ENST00000586699.1	EIF1	eukaryotic translation initiation factor 1
chr3_+_6902794	0.07	ENST00000357716.4 ENST00000486284.1 ENST00000389336.4 ENST00000403881.1 ENST00000402647.2	GRM7	glutamate receptor, metabotropic 7
chr19_-_54824344	0.06	ENST00000346508.3 ENST00000446712.3 ENST00000432233.3 ENST00000301219.3	LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr3_+_186435065	0.06	ENST00000287611.2 ENST00000265023.4	KNG1	kininogen 1
chr4_+_77870960	0.04	ENST00000505788.1 ENST00000510515.1 ENST00000504637.1	SEPT11	septin 11
chr11_+_92085707	0.04	ENST00000525166.1	FAT3	FAT atypical cadherin 3
chr5_-_145562147	0.03	ENST00000545646.1 ENST00000274562.9 ENST00000510191.1 ENST00000394434.2	LARS	leucyl-tRNA synthetase
chr9_-_117568365	0.03	ENST00000374045.4	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15
chr1_-_150602035	0.03	ENST00000503241.1 ENST00000369016.4 ENST00000339643.5 ENST00000271690.8 ENST00000356527.5 ENST00000362052.7 ENST00000503345.1 ENST00000369014.5 ENST00000369009.3	ENSA	endosulfine alpha
chr17_+_44588877	0.02	ENST00000576629.1	LRRC37A2	leucine rich repeat containing 37, member A2
chr19_+_44455368	0.01	ENST00000591168.1 ENST00000587682.1 ENST00000251269.5	ZNF221	zinc finger protein 221

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.3	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.9	11.3	GO:0043203	axon hillock(GO:0043203)
0.8	9.8	GO:0005577	fibrinogen complex(GO:0005577)
0.7	2.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.4	7.7	GO:0031089	platelet dense granule lumen(GO:0031089)
0.4	3.5	GO:0071953	elastic fiber(GO:0071953)
0.4	2.8	GO:0070552	BRISC complex(GO:0070552)
0.2	1.6	GO:0046581	intercellular canaliculus(GO:0046581)
0.2	0.6	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.1	1.2	GO:0005915	zonula adherens(GO:0005915)
0.0	3.3	GO:0031526	brush border membrane(GO:0031526)
0.0	1.1	GO:0097228	sperm principal piece(GO:0097228)
0.0	1.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	1.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	2.6	GO:0005902	microvillus(GO:0005902)
0.0	7.1	GO:0072562	blood microparticle(GO:0072562)
0.0	0.6	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.6	GO:0010369	chromocenter(GO:0010369)
0.0	0.4	GO:0030897	HOPS complex(GO:0030897)
0.0	2.8	GO:0005901	caveola(GO:0005901)
0.0	1.1	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:1990037	Lewy body core(GO:1990037)
0.0	3.7	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	1.4	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.2	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	1.0	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.7	GO:0031904	endosome lumen(GO:0031904)
0.0	0.9	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	17.2	GO:0005615	extracellular space(GO:0005615)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.3	8.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	3.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	2.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	1.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	4.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	3.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	2.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	2.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	3.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	3.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	2.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	11.3	GO:0071279	cellular response to cobalt ion(GO:0071279)
1.4	4.2	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.2	3.5	GO:0006982	response to lipid hydroperoxide(GO:0006982)
1.1	3.2	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.1	3.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.9	2.8	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.9	2.8	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.9	2.7	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.8	2.3	GO:0019557	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.8	7.7	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.8	3.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.8	3.0	GO:2000230	negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5	1.6	GO:0050787	antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) response to antineoplastic agent(GO:0097327)
0.5	6.5	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.5	1.4	GO:0090427	activation of meiosis(GO:0090427)
0.4	2.1	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.4	3.3	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.4	2.8	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.4	1.6	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4	1.1	GO:2000282	negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.4	1.1	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.4	1.1	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.3	3.5	GO:0048251	elastic fiber assembly(GO:0048251)
0.3	1.9	GO:0034201	response to oleic acid(GO:0034201)
0.3	1.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.3	2.6	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.3	3.7	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.3	0.8	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.3	4.8	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.2	1.5	GO:0015811	L-cystine transport(GO:0015811)
0.2	1.4	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2	0.5	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2	2.6	GO:2000194	regulation of female gonad development(GO:2000194)
0.2	3.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.5	GO:0009956	radial pattern formation(GO:0009956)
0.1	0.8	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1	0.7	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1	0.6	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.4	GO:0010585	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1	0.6	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1	0.5	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.1	1.9	GO:0097186	amelogenesis(GO:0097186)
0.1	0.5	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	0.3	GO:0035606	induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1	1.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1	0.3	GO:0061386	soft palate development(GO:0060023) closure of optic fissure(GO:0061386)
0.1	0.2	GO:1905064	cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) phenotypic switching(GO:0036166) negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of phenotypic switching(GO:1900239) negative regulation of vascular smooth muscle cell differentiation(GO:1905064) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1	1.2	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.3	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.8	GO:0046325	negative regulation of glucose import(GO:0046325)
0.1	1.2	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.2	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	1.9	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.3	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.2	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	2.9	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.4	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.3	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0	2.7	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.2	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.2	GO:0001554	luteolysis(GO:0001554)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.4	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.6	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.4	GO:0071027	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.5	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0	0.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	1.4	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.4	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.5	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.4	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.3	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0070942	neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.9	GO:0070527	platelet aggregation(GO:0070527)
0.0	1.2	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.3	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	1.5	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.0	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.0	1.0	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0014050	negative regulation of glutamate secretion(GO:0014050)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	7.7	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.9	2.8	GO:0004122	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.9	2.8	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.9	2.7	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6	1.9	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.6	2.3	GO:0016841	ammonia-lyase activity(GO:0016841)
0.5	2.6	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.5	1.9	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.4	2.7	GO:0030492	hemoglobin binding(GO:0030492)
0.4	2.8	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4	1.1	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.4	1.4	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3	2.7	GO:0050692	DBD domain binding(GO:0050692)
0.3	3.5	GO:0008430	selenium binding(GO:0008430)
0.3	0.8	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.3	2.4	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3	2.1	GO:0001849	complement component C1q binding(GO:0001849)
0.3	0.8	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.2	6.5	GO:0001848	complement binding(GO:0001848)
0.2	0.5	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.4	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.1	0.3	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	0.7	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	1.6	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.1	0.5	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.6	GO:0004925	prolactin receptor activity(GO:0004925)
0.1	0.6	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	0.3	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	1.7	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.4	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.1	10.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.0	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.1	4.2	GO:0016504	peptidase activator activity(GO:0016504)
0.1	0.3	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1	1.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	1.2	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1	0.4	GO:0008142	oxysterol binding(GO:0008142)
0.1	1.2	GO:0050811	GABA receptor binding(GO:0050811)
0.1	1.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	6.4	GO:0005179	hormone activity(GO:0005179)
0.0	3.7	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.2	GO:0038025	glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.0	1.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	1.1	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.8	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	5.8	GO:0030674	protein binding, bridging(GO:0030674)
0.0	1.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	3.5	GO:0005178	integrin binding(GO:0005178)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	3.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.5	GO:0001972	retinoic acid binding(GO:0001972)
0.0	3.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.7	GO:0004601	peroxidase activity(GO:0004601)
0.0	0.0	GO:0004819	glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0	1.3	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.2	GO:0032183	SUMO binding(GO:0032183)
0.0	1.4	GO:0009055	electron carrier activity(GO:0009055)
0.0	3.1	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0050321	tau-protein kinase activity(GO:0050321)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	9.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	2.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	3.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	2.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	3.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	3.7	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	1.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	3.8	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	10.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	2.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	3.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	2.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.6	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.8	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.7	PID RHOA REG PATHWAY	Regulation of RhoA activity