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ENCODE cell lines, expression (Ernst 2011)
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Results for MYF6
Z-value: 1.39
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Transcription factors associated with MYF6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYF6 | hg19_v2_chr12_+_81101277_81101321 | -0.10 | 7.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYF6
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_53253112 | 4.82 |
ENST00000568673.1 ENST00000562847.1 ENST00000568147.1 |
TCF4 |
transcription factor 4 |
| chrX_-_38080077 | 4.80 |
ENST00000378533.3 ENST00000544439.1 ENST00000432886.2 ENST00000538295.1 |
SRPX |
sushi-repeat containing protein, X-linked |
| chr18_-_53253323 | 4.49 |
ENST00000540999.1 ENST00000563888.2 |
TCF4 |
transcription factor 4 |
| chr9_+_116298778 | 3.59 |
ENST00000462143.1 |
RGS3 |
regulator of G-protein signaling 3 |
| chr11_+_114168773 | 2.96 |
ENST00000542647.1 ENST00000545255.1 |
NNMT |
nicotinamide N-methyltransferase |
| chr13_-_72440901 | 2.43 |
ENST00000359684.2 |
DACH1 |
dachshund homolog 1 (Drosophila) |
| chr13_-_108518986 | 2.33 |
ENST00000375915.2 |
FAM155A |
family with sequence similarity 155, member A |
| chr1_-_57045228 | 2.08 |
ENST00000371250.3 |
PPAP2B |
phosphatidic acid phosphatase type 2B |
| chr5_-_94620239 | 1.97 |
ENST00000515393.1 |
MCTP1 |
multiple C2 domains, transmembrane 1 |
| chr10_+_89419370 | 1.91 |
ENST00000361175.4 ENST00000456849.1 |
PAPSS2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.4 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.9 | 7.2 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.6 | 6.0 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 4.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.3 | 3.4 | GO:2000680 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.3 | 3.3 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.9 | 2.6 | GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) |
| 0.6 | 2.5 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.1 | 2.5 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.1 | 2.2 | GO:1901881 | positive regulation of protein depolymerization(GO:1901881) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 9.3 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.3 | 3.7 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.7 | 3.0 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 0.9 | 2.6 | GO:0016603 | glutaminyl-peptide cyclotransferase activity(GO:0016603) |
| 0.2 | 2.6 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 2.5 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.2 | 2.4 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.1 | 2.2 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
| 0.7 | 2.0 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 0.6 | 1.9 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 5.3 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 3.0 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.0 | 2.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 2.0 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.9 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 1.7 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 1.5 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 1.5 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 1.5 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.5 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 8.8 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 8.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 5.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 4.8 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 2.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 2.0 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.6 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 1.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.1 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 6.8 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 4.9 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 4.4 | GO:0005604 | basement membrane(GO:0005604) |
| 0.3 | 3.4 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.1 | 3.0 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.4 | 2.8 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.0 | 2.8 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 2.6 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 2.6 | GO:0042641 | actomyosin(GO:0042641) |