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ENCODE cell lines, expression (Ernst 2011)
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Results for NFIA
Z-value: 0.96
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Transcription factors associated with NFIA
Network of associatons between targets according to the STRING database.
First level regulatory network of NFIA
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_129932974 | 2.16 |
ENST00000445470.2 ENST00000222482.4 ENST00000492072.1 ENST00000473956.1 ENST00000493259.1 ENST00000486598.1 |
CPA4 |
carboxypeptidase A4 |
| chr18_+_61143994 | 1.93 |
ENST00000382771.4 |
SERPINB5 |
serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| chr12_-_52911718 | 1.83 |
ENST00000548409.1 |
KRT5 |
keratin 5 |
| chr11_-_122931881 | 1.81 |
ENST00000526110.1 ENST00000227378.3 |
HSPA8 |
heat shock 70kDa protein 8 |
| chr19_+_41725088 | 1.79 |
ENST00000301178.4 |
AXL |
AXL receptor tyrosine kinase |
| chr4_+_169552748 | 1.65 |
ENST00000504519.1 ENST00000512127.1 |
PALLD |
palladin, cytoskeletal associated protein |
| chr17_-_10325261 | 1.63 |
ENST00000403437.2 |
MYH8 |
myosin, heavy chain 8, skeletal muscle, perinatal |
| chr14_+_73704201 | 1.63 |
ENST00000340738.5 ENST00000427855.1 ENST00000381166.3 |
PAPLN |
papilin, proteoglycan-like sulfated glycoprotein |
| chr7_-_41742697 | 1.61 |
ENST00000242208.4 |
INHBA |
inhibin, beta A |
| chr4_-_111558135 | 1.51 |
ENST00000394598.2 ENST00000394595.3 |
PITX2 |
paired-like homeodomain 2 |
Gene Ontology Analysis
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.2 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 3.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 2.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 2.4 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 1.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.9 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.6 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.6 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 1.3 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.5 | 2.9 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.6 | 2.5 | GO:0097325 | melanocyte proliferation(GO:0097325) |
| 0.5 | 2.5 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.0 | 2.5 | GO:0007601 | visual perception(GO:0007601) |
| 0.1 | 2.3 | GO:0030318 | melanocyte differentiation(GO:0030318) |
| 0.0 | 2.3 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.2 | 2.0 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.1 | 1.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 1.7 | GO:0015688 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | GO:0032982 | myosin filament(GO:0032982) |
| 0.2 | 2.6 | GO:0033643 | host cell part(GO:0033643) |
| 0.4 | 2.5 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.2 | 2.5 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 2.4 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 2.0 | GO:0045095 | keratin filament(GO:0045095) |
| 0.5 | 1.6 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 1.6 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 1.6 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 1.5 | GO:0001533 | cornified envelope(GO:0001533) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 2.9 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.2 | 2.5 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.2 | 2.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 2.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 2.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 2.3 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 2.3 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 2.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 2.0 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.1 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 2.4 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 2.4 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 1.8 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 1.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 1.2 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 1.1 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 1.0 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.1 | 0.9 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.9 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |