Project
ENCODE cell lines, expression (Ernst 2011)
Navigation
Downloads
Results for WRNIP1
Z-value: 2.07
Motif logo
Transcription factors associated with WRNIP1
Network of associatons between targets according to the STRING database.
First level regulatory network of WRNIP1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_35691017 | 8.02 |
ENST00000378292.3 |
TPM2 |
tropomyosin 2 (beta) |
| chr1_-_20812690 | 7.49 |
ENST00000375078.3 |
CAMK2N1 |
calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| chr14_-_105420241 | 6.81 |
ENST00000557457.1 |
AHNAK2 |
AHNAK nucleoprotein 2 |
| chrX_-_38080077 | 6.02 |
ENST00000378533.3 ENST00000544439.1 ENST00000432886.2 ENST00000538295.1 |
SRPX |
sushi-repeat containing protein, X-linked |
| chr8_+_22437965 | 5.39 |
ENST00000409141.1 ENST00000265810.4 |
PDLIM2 |
PDZ and LIM domain 2 (mystique) |
| chr12_-_77272765 | 5.27 |
ENST00000547435.1 ENST00000552330.1 ENST00000546966.1 ENST00000311083.5 |
CSRP2 |
cysteine and glycine-rich protein 2 |
| chr7_-_41740181 | 5.18 |
ENST00000442711.1 |
INHBA |
inhibin, beta A |
| chr11_+_114128522 | 5.05 |
ENST00000535401.1 |
NNMT |
nicotinamide N-methyltransferase |
| chr3_+_105085734 | 5.02 |
ENST00000306107.5 |
ALCAM |
activated leukocyte cell adhesion molecule |
| chr5_+_135385202 | 5.02 |
ENST00000514554.1 |
TGFBI |
transforming growth factor, beta-induced, 68kDa |
Gene Ontology Analysis
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 43.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.5 | 40.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 39.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 33.9 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.3 | 33.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 23.0 | GO:0003779 | actin binding(GO:0003779) |
| 0.7 | 21.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 19.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 1.2 | 18.8 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.1 | 17.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 70.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.7 | 61.3 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.3 | 53.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.5 | 21.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.4 | 21.7 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.3 | 20.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.9 | 20.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 20.0 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.4 | 19.9 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.1 | 17.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 74.6 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.2 | 63.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.6 | 57.3 | GO:0005604 | basement membrane(GO:0005604) |
| 0.2 | 39.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.3 | 26.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 1.5 | 24.5 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 1.2 | 21.9 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.2 | 18.9 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 18.3 | GO:0044432 | endoplasmic reticulum part(GO:0044432) |
| 1.2 | 16.9 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 42.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.3 | 35.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.5 | 33.5 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.7 | 27.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.9 | 23.2 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.4 | 21.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.5 | 16.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 15.0 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.4 | 14.6 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 13.4 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 21.9 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.4 | 21.1 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.5 | 15.0 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.5 | 14.8 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 1.3 | 14.4 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 1.4 | 12.7 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.4 | 11.9 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.5 | 11.8 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.2 | 11.8 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.3 | 11.5 | GO:0097435 | fibril organization(GO:0097435) |