Motif ID: ATF4.p2

Z-value: 1.461


Transcription factors associated with ATF4.p2:

Gene SymbolEntrez IDGene Name
ATF4 468 activating transcription factor 4 (tax-responsive enhancer element B67)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF4chr22_+_382465090.019.7e-01Click!


Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_586997 2.529 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr4_+_75699652 1.375 NM_001657
AREG
amphiregulin
chr7_-_140270749 1.225 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr7_-_44992729 1.201 C7orf40
chromosome 7 open reading frame 40
chr5_+_112877251 1.122 NM_022828
YTHDC2
YTH domain containing 2
chr3_-_33734544 1.034 CLASP2
cytoplasmic linker associated protein 2
chr4_+_75529716 1.029 NM_001657
AREG
amphiregulin
chr4_+_170778265 1.026 NM_001829
NM_173872
CLCN3

chloride channel 3

chr3_+_10043139 0.958 FANCD2
Fanconi anemia, complementation group D2
chr7_+_140042932 0.939 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr7_+_151353707 0.884 NM_022087
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr18_+_18767275 0.879 NM_002894
RBBP8
retinoblastoma binding protein 8
chr14_-_54563554 0.878 NM_001008396
NM_007086
WDHD1

WD repeat and HMG-box DNA binding protein 1

chr4_-_186584031 0.876 NM_018359
UFSP2
UFM1-specific peptidase 2
chr1_+_109090868 0.874 STXBP3
syntaxin binding protein 3
chr17_+_54124952 0.870 NM_002876
NM_058216
RAD51C

RAD51 homolog C (S. cerevisiae)

chr3_+_171558188 0.856 SKIL
SKI-like oncogene
chr14_+_67156386 0.849 ARG2
arginase, type II
chr3_-_33734747 0.845 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr12_+_95825131 0.827 NM_001135176
NM_001135177
NM_152905
NEDD1


neural precursor cell expressed, developmentally down-regulated 1


chr19_-_9556166 0.825 NM_001008727
ZNF121
zinc finger protein 121
chr16_+_22732982 0.806 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr9_-_124066838 0.802 RBM18
RNA binding motif protein 18
chr3_+_171558215 0.790 SKIL
SKI-like oncogene
chr14_+_67156323 0.783 NM_001172
ARG2
arginase, type II
chr11_+_4072635 0.779 RRM1
ribonucleotide reductase M1
chr7_+_151353775 0.778 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr9_-_124066901 0.765 NM_033117
RBM18
RNA binding motif protein 18
chr3_+_142143329 0.761 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr7_+_151353759 0.747 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr7_-_158314963 0.747 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr14_-_54563520 0.744 WDHD1
WD repeat and HMG-box DNA binding protein 1
chr1_+_110328955 0.740 AHCYL1
adenosylhomocysteinase-like 1
chr3_+_142569988 0.735 ZBTB38
zinc finger and BTB domain containing 38
chr4_-_84475328 0.732 NM_001166498
NM_006665
HPSE

heparanase

chr11_+_95163256 0.731 NM_014679
CEP57
centrosomal protein 57kDa
chr1_+_110328830 0.730 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr17_+_54997667 0.713 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr8_-_17148637 0.703 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr8_+_26204921 0.698 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_-_8982107 0.698 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr3_-_16281287 0.690 NM_001047434
NM_206831
DPH3

DPH3, KTI11 homolog (S. cerevisiae)

chr17_+_24095135 0.689 NM_004295
TRAF4
TNF receptor-associated factor 4
chr11_+_4072499 0.681 NM_001033
RRM1
ribonucleotide reductase M1
chr3_+_142939827 0.680 RNF7
ring finger protein 7
chr12_+_22669275 0.669 NM_001039481
NM_018638
ETNK1

ethanolamine kinase 1

chr3_+_171558143 0.666 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr5_+_56505412 0.664 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr11_+_4072653 0.663 RRM1
ribonucleotide reductase M1
chr7_-_158314945 0.658 ESYT2
extended synaptotagmin-like protein 2
chrX_-_7855400 0.655 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr1_+_110328941 0.654 AHCYL1
adenosylhomocysteinase-like 1
chr1_+_110329279 0.651 AHCYL1
adenosylhomocysteinase-like 1
chr1_+_110329224 0.651 AHCYL1
adenosylhomocysteinase-like 1
chr8_+_26204960 0.651 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_+_109090789 0.650 NM_007269
STXBP3
syntaxin binding protein 3
chr1_+_110328922 0.643 AHCYL1
adenosylhomocysteinase-like 1
chr12_+_22669352 0.642 ETNK1
ethanolamine kinase 1
chr3_-_151963607 0.641 SIAH2
seven in absentia homolog 2 (Drosophila)
chr3_-_102878301 0.641 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr5_+_56505608 0.638 GPBP1
GC-rich promoter binding protein 1
chr7_-_105712565 0.634 NAMPT
nicotinamide phosphoribosyltransferase
chr16_+_79906084 0.632 GAN
gigaxonin
chr1_-_201162991 0.631 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr1_+_166414706 0.629 NM_001031800
NM_152902
TIPRL

TIP41, TOR signaling pathway regulator-like (S. cerevisiae)

chr3_+_10043123 0.625 FANCD2
Fanconi anemia, complementation group D2
chr11_-_28086263 0.624 KIF18A
kinesin family member 18A
chr4_-_80079393 0.622 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr7_+_16759845 0.618 NM_014399
TSPAN13
tetraspanin 13
chr9_+_110736541 0.616 C9orf6
chromosome 9 open reading frame 6
chr16_+_79906065 0.609 NM_022041
GAN
gigaxonin
chr1_+_110328850 0.608 AHCYL1
adenosylhomocysteinase-like 1
chr3_-_151963653 0.606 NM_005067
SIAH2
seven in absentia homolog 2 (Drosophila)
chr7_+_106991638 0.601 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr6_+_27890772 0.600 NM_003521
HIST1H2BM
histone cluster 1, H2bm
chr22_+_19601619 0.596 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr1_+_109090876 0.593


chr3_+_10043097 0.592 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr1_-_148079357 0.587 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr1_-_156923111 0.586 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_+_47553399 0.583 NM_012120
CD2AP
CD2-associated protein
chr6_-_106880300 0.580 NM_004849
ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr9_+_110736247 0.576 C9orf6
chromosome 9 open reading frame 6
chr8_+_23442413 0.572 SLC25A37
solute carrier family 25, member 37
chr4_-_104338924 0.568 NM_001813
CENPE
centromere protein E, 312kDa
chr1_+_27591738 0.565 NM_005281
GPR3
G protein-coupled receptor 3
chr9_+_124066973 0.564 MRRF
mitochondrial ribosome recycling factor
chr5_-_172130766 0.563 NM_004417
DUSP1
dual specificity phosphatase 1
chr1_-_172103745 0.561 GAS5
growth arrest-specific 5 (non-protein coding)
chr2_+_74610751 0.555 HTRA2
HtrA serine peptidase 2
chr18_+_55718171 0.548 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr21_-_39642808 0.541 HMGN1
high-mobility group nucleosome binding domain 1
chr6_-_53321545 0.541 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr1_-_70443851 0.540 NM_017768
LRRC40
leucine rich repeat containing 40
chr11_+_62405736 0.540 SLC3A2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr8_+_23442307 0.539 NM_016612
SLC25A37
solute carrier family 25, member 37
chr11_-_118693021 0.539 NM_006500
MCAM
melanoma cell adhesion molecule
chr3_+_38181972 0.535 NM_005109
OXSR1
oxidative-stress responsive 1
chr1_-_201162938 0.533 KLHL12
kelch-like 12 (Drosophila)
chr8_+_26204997 0.533 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_+_150112537 0.530 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chrX_-_7855764 0.530 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr1_-_148818629 0.529 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr18_-_257987 0.526 NM_005131
THOC1
THO complex 1
chr4_+_129021465 0.525 NM_001190799
NM_014264
PLK4

polo-like kinase 4

chr3_+_101019357 0.524 NM_032359
C3orf26
chromosome 3 open reading frame 26
chr17_+_30938433 0.524 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr6_-_53321658 0.523 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chrX_+_41078787 0.521 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr3_+_44746101 0.520 NM_145044
ZNF501
zinc finger protein 501
chr20_-_55718351 0.518 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr15_-_70399301 0.516 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr11_-_28086277 0.515 NM_031217
KIF18A
kinesin family member 18A
chr17_+_30938391 0.512 NM_001030006
NM_001282
AP2B1

adaptor-related protein complex 2, beta 1 subunit

chr10_+_85889164 0.506 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr4_-_100703847 0.506 NM_152292
RG9MTD2
RNA (guanine-9-) methyltransferase domain containing 2
chr10_-_33287137 0.499 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr17_+_26446067 0.498 NM_000267
NM_001042492
NM_001128147
NF1


neurofibromin 1


chr19_-_9510257 0.497 NM_024106
ZNF426
zinc finger protein 426
chr7_-_105712646 0.496 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr4_-_113777470 0.495 C4orf21
chromosome 4 open reading frame 21
chr11_+_9439087 0.493 NM_003442
ZNF143
zinc finger protein 143
chr6_-_106880182 0.490 ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr7_+_107318821 0.490 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr7_+_107318852 0.489 DLD
dihydrolipoamide dehydrogenase
chr3_-_151963577 0.489 SIAH2
seven in absentia homolog 2 (Drosophila)
chr2_-_86704446 0.488 RNF103
ring finger protein 103
chr1_+_89871281 0.487 LRRC8C
leucine rich repeat containing 8 family, member C
chr11_-_61341011 0.483 NM_013402
FADS1
fatty acid desaturase 1
chr12_+_49443903 0.483 NM_005171
ATF1
activating transcription factor 1
chr4_+_129021514 0.473 NM_001190801
PLK4
polo-like kinase 4
chr14_+_54563587 0.469 NM_080867
NM_199421
SOCS4

suppressor of cytokine signaling 4

chr22_+_19601721 0.468 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr15_+_38673734 0.467 NM_144508
NM_170589
CASC5

cancer susceptibility candidate 5

chr4_-_110574363 0.465 1/2-SBSRNA4
lncRNA_BC009800
chr19_+_54226941 0.463 NM_033378
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr1_+_51855343 0.459 OSBPL9
oxysterol binding protein-like 9
chr12_+_95825374 0.457 NM_001135175
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr1_-_243092581 0.455 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr3_+_101462375 0.454 NM_018309
TBC1D23
TBC1 domain family, member 23
chr6_-_29703725 0.453 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr15_+_38673509 0.452 CASC5
cancer susceptibility candidate 5
chr4_+_142361494 0.449 NM_014487
ZNF330
zinc finger protein 330
chr3_-_102888090 0.446 NM_000986
RPL24
ribosomal protein L24
chr7_-_26206891 0.446 NM_002137
NM_031243
HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

chr6_-_53321706 0.444 NM_021814
ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr7_-_129379947 0.444 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr19_+_62523636 0.442 NM_213598
ZNF543
zinc finger protein 543
chr4_+_142361523 0.442 ZNF330
zinc finger protein 330
chr11_-_28086222 0.440 KIF18A
kinesin family member 18A
chr5_-_72897132 0.436 NM_023039
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr4_-_170770111 0.434 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr4_-_39044300 0.434 NM_002913
RFC1
replication factor C (activator 1) 1, 145kDa
chr10_-_33287184 0.433 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr3_+_38182120 0.433 OXSR1
oxidative-stress responsive 1
chrX_-_102452461 0.432 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr6_-_121697305 0.430 NM_152730
C6orf170
chromosome 6 open reading frame 170
chr6_-_106880222 0.429 ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr8_+_23442331 0.425 SLC25A37
solute carrier family 25, member 37
chr5_-_1935764 0.421 NM_016358
IRX4
iroquois homeobox 4
chr12_+_132217285 0.420 NM_015394
ZNF10
zinc finger protein 10
chr2_+_24003648 0.416 UBXN2A
UBX domain protein 2A
chr6_-_29703913 0.414 NM_021903
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_46957317 0.411 NM_014774
KIAA0494
KIAA0494
chr7_+_20336849 0.411 ITGB8
integrin, beta 8
chr7_+_129497572 0.411 NM_014997
KLHDC10
kelch domain containing 10
chr15_-_64577122 0.411 NM_006049
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr6_-_27208507 0.410 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr12_-_91063441 0.410 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr11_-_77963517 0.409 NM_024678
NARS2
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr19_-_58354091 0.409 NM_001172674
NM_001172675
NM_032584
ZNF347


zinc finger protein 347


chrX_+_101910713 0.409 LOC100287765
hypothetical LOC100287765
chr3_+_44355217 0.408 C3orf23
chromosome 3 open reading frame 23
chr3_+_44354594 0.405 NM_001029840
C3orf23
chromosome 3 open reading frame 23
chr10_+_118990573 0.403 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr8_-_17148474 0.402 CNOT7
CCR4-NOT transcription complex, subunit 7
chr1_+_91739241 0.402 NM_001134420
CDC7
cell division cycle 7 homolog (S. cerevisiae)
chr2_-_278181 0.402 NM_001002919
FAM150B
family with sequence similarity 150, member B
chr9_+_110736493 0.402 NM_017832
C9orf6
chromosome 9 open reading frame 6
chr12_+_52665196 0.401 NM_017409
HOXC10
homeobox C10
chr3_+_170973870 0.400 MYNN
myoneurin
chr18_+_2561587 0.398 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr19_-_9592883 0.398 NM_152289
ZNF561
zinc finger protein 561
chr3_+_142939725 0.398 NM_014245
NM_183237
RNF7

ring finger protein 7

chr6_-_31882558 0.397 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_+_92151599 0.395 NM_016023
OTUD6B
OTU domain containing 6B
chr17_+_20165049 0.394 CCDC144C
coiled-coil domain containing 144C
chr7_-_23537968 0.393 NM_013293
TRA2A
transformer 2 alpha homolog (Drosophila)
chr6_-_106880229 0.393 ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chrX_+_67635348 0.393 NM_001195214
NM_173834
YIPF6

Yip1 domain family, member 6

chr20_+_57948803 0.393 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr12_-_38123027 0.392 NM_001173463
NM_001173464
NM_001173465
NM_017641
KIF21A



kinesin family member 21A



chrX_-_13866565 0.392 NM_001001994
GPM6B
glycoprotein M6B
chr12_-_31773210 0.392 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr11_-_18300246 0.390 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr6_-_42821815 0.389 NM_003192
TBCC
tubulin folding cofactor C
chr17_+_54124928 0.388 RAD51C
RAD51 homolog C (S. cerevisiae)
chr1_+_51474531 0.387 NM_014372
RNF11
ring finger protein 11
chr3_+_44354927 0.387 NM_001029839
NM_173826
C3orf23

chromosome 3 open reading frame 23

chr12_+_67290975 0.385 RAP1B
RAP1B, member of RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.50 4.89e-17 GO:0044260 cellular macromolecule metabolic process
1.36 4.32e-15 GO:0044237 cellular metabolic process
1.42 4.89e-14 GO:0043170 macromolecule metabolic process
1.33 4.76e-13 GO:0044238 primary metabolic process
1.58 1.42e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 5.11e-11 GO:0008152 metabolic process
1.64 9.17e-11 GO:0090304 nucleic acid metabolic process
1.51 9.52e-11 GO:0034641 cellular nitrogen compound metabolic process
1.49 2.48e-10 GO:0006807 nitrogen compound metabolic process
2.08 1.49e-07 GO:0022403 cell cycle phase
1.50 1.94e-07 GO:0044267 cellular protein metabolic process
1.95 4.72e-07 GO:0022402 cell cycle process
1.91 1.50e-06 GO:0033554 cellular response to stress
2.15 4.77e-06 GO:0006974 response to DNA damage stimulus
1.88 1.11e-05 GO:0046907 intracellular transport
1.57 2.24e-05 GO:0006996 organelle organization
2.02 2.28e-05 GO:0000278 mitotic cell cycle
1.74 2.28e-05 GO:0007049 cell cycle
1.37 9.89e-05 GO:0019538 protein metabolic process
2.11 2.07e-04 GO:0000279 M phase
1.89 2.18e-04 GO:0006396 RNA processing
2.24 3.79e-04 GO:0006281 DNA repair
1.91 4.22e-04 GO:0006259 DNA metabolic process
1.37 7.62e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.48 9.35e-04 GO:0016070 RNA metabolic process
2.25 1.04e-03 GO:0051325 interphase
1.46 1.04e-03 GO:0010467 gene expression
1.48 1.33e-03 GO:0034645 cellular macromolecule biosynthetic process
1.37 1.38e-03 GO:0071842 cellular component organization at cellular level
3.07 1.55e-03 GO:0050657 nucleic acid transport
3.07 1.55e-03 GO:0050658 RNA transport
3.07 1.55e-03 GO:0051236 establishment of RNA localization
1.47 1.64e-03 GO:0009059 macromolecule biosynthetic process
1.58 2.70e-03 GO:0044248 cellular catabolic process
2.97 2.92e-03 GO:0006403 RNA localization
1.54 3.28e-03 GO:0051641 cellular localization
1.29 3.51e-03 GO:0071840 cellular component organization or biogenesis
1.58 3.97e-03 GO:0051649 establishment of localization in cell
2.19 4.21e-03 GO:0000087 M phase of mitotic cell cycle
2.19 4.21e-03 GO:0051329 interphase of mitotic cell cycle
1.10 4.81e-03 GO:0009987 cellular process
2.07 9.77e-03 GO:0044257 cellular protein catabolic process
2.11 1.02e-02 GO:0006511 ubiquitin-dependent protein catabolic process
2.12 1.14e-02 GO:0048285 organelle fission
2.14 1.26e-02 GO:0000280 nuclear division
2.14 1.26e-02 GO:0007067 mitosis
1.28 1.30e-02 GO:0016043 cellular component organization
2.93 1.60e-02 GO:0051028 mRNA transport
2.07 1.70e-02 GO:0019941 modification-dependent protein catabolic process
1.74 1.89e-02 GO:0051276 chromosome organization
2.05 2.00e-02 GO:0043632 modification-dependent macromolecule catabolic process
2.64 2.40e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.98 2.44e-02 GO:0030163 protein catabolic process
2.01 3.23e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.45 3.35e-02 GO:0009056 catabolic process
1.60 3.52e-02 GO:0015031 protein transport
1.59 3.86e-02 GO:0045184 establishment of protein localization
1.33 4.25e-02 GO:0044249 cellular biosynthetic process
15.08 4.29e-02 GO:0070584 mitochondrion morphogenesis
1.46 4.80e-02 GO:0033036 macromolecule localization
1.76 4.82e-02 GO:0016071 mRNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.33 1.50e-27 GO:0043231 intracellular membrane-bounded organelle
1.33 2.28e-27 GO:0043227 membrane-bounded organelle
1.23 2.82e-26 GO:0044424 intracellular part
1.22 2.92e-26 GO:0005622 intracellular
1.27 2.20e-23 GO:0043229 intracellular organelle
1.27 4.36e-23 GO:0043226 organelle
1.42 2.52e-18 GO:0005634 nucleus
1.25 1.32e-13 GO:0005737 cytoplasm
1.35 1.69e-12 GO:0044446 intracellular organelle part
1.33 9.00e-12 GO:0044422 organelle part
1.58 3.18e-10 GO:0070013 intracellular organelle lumen
1.59 5.24e-10 GO:0044428 nuclear part
1.56 1.31e-09 GO:0043233 organelle lumen
1.54 3.70e-09 GO:0031974 membrane-enclosed lumen
1.62 4.86e-09 GO:0031981 nuclear lumen
2.20 1.66e-08 GO:0005694 chromosome
2.21 4.40e-07 GO:0044427 chromosomal part
1.66 6.15e-07 GO:0005654 nucleoplasm
1.24 1.98e-06 GO:0044444 cytoplasmic part
1.34 4.27e-04 GO:0043228 non-membrane-bounded organelle
1.34 4.27e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.29 4.87e-04 GO:0032991 macromolecular complex
3.22 1.79e-03 GO:0000776 kinetochore
1.37 2.78e-03 GO:0005829 cytosol
2.64 2.84e-03 GO:0000775 chromosome, centromeric region
1.76 9.36e-03 GO:0030529 ribonucleoprotein complex
1.76 9.55e-03 GO:0005730 nucleolus
2.48 1.81e-02 GO:0000793 condensed chromosome
3.10 2.82e-02 GO:0000777 condensed chromosome kinetochore
12.06 3.50e-02 GO:0005663 DNA replication factor C complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 1.12e-08 GO:0005515 protein binding
1.12 7.30e-08 GO:0005488 binding
1.38 8.23e-07 GO:0003676 nucleic acid binding
1.61 9.17e-07 GO:0005524 ATP binding
1.54 1.18e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.60 1.48e-06 GO:0032559 adenyl ribonucleotide binding
1.59 2.17e-06 GO:0030554 adenyl nucleotide binding
1.46 2.76e-06 GO:0000166 nucleotide binding
1.51 4.09e-06 GO:0032553 ribonucleotide binding
1.51 4.09e-06 GO:0032555 purine ribonucleotide binding
1.50 6.20e-06 GO:0017076 purine nucleotide binding
1.72 1.88e-04 GO:0003723 RNA binding
1.21 1.25e-03 GO:0003824 catalytic activity
1.31 2.05e-02 GO:0003677 DNA binding
1.60 2.12e-02 GO:0019899 enzyme binding